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ONTOLOGY REPORT - ANNOTATIONS

Term:osmosensor activity
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Accession:GO:0005034 term browser browse the term
Definition:Sensing extracellular osmolarity to initiate a change in cell activity, and spanning the membrane of the cell.


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osmosensor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 enables ISO MGI:2667379 (PMID:11025659), (PMID:12777254) RGD PMID:11025659 PMID:12777254 NCBI chr12:41,938,533...41,977,517
Ensembl chr12:41,938,560...41,977,517 		JBrowse link
osmolarity-sensing monoatomic cation channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Scn7a sodium voltage-gated channel alpha subunit 7 enables IDA
ISO		 PMID:21084682
(MGI:3628881|PMID:11992118)		 RGD PMID:11992118 PMID:21084682 MGI:3628881, RGD:401966867 NCBI chr 3:51,335,841...51,438,308
Ensembl chr 3:51,335,841...51,438,256 		JBrowse link
G Tmem63a transmembrane protein 63a enables ISO (MGI:6378787|PMID:27045885) RGD PMID:27045885 MGI:6378787 NCBI chr13:92,662,872...92,696,186
Ensembl chr13:92,663,968...92,696,183 		JBrowse link
G Tmem63b transmembrane protein 63B enables ISO (MGI:6378298|PMID:31243992), (MGI:6378787|PMID:27045885), (MGI:6514514|PMID:32375046) RGD PMID:27045885 PMID:31243992 PMID:32375046 MGI:6378298 MGI:6378787 MGI:6514514 NCBI chr 9:15,313,867...15,340,722
Ensembl chr 9:15,320,432...15,340,720 		JBrowse link
G Tmem63c transmembrane protein 63c enables ISS
ISO		 GO_REF:0000024
(MGI:6378787|PMID:27045885)		 UniProt
RGD		 PMID:27045885 GO_REF:0000024 MGI:6378787 NCBI chr 6:106,667,389...106,738,778
Ensembl chr 6:106,672,934...106,736,990 		JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 IDA RGD PMID:18279313 RGD:10047048 NCBI chr 5:4,379,862...4,434,133
Ensembl chr 5:4,379,999...4,433,570 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21010
    small molecule sensor activity 42
      osmosensor activity 6
        osmolarity-sensing monoatomic cation channel activity 5
Path 2
Term Annotations click to browse term
  molecular_function 21010
    molecular transducer activity 2637
      signaling receptor activity 2637
        transmembrane signaling receptor activity 2427
          osmosensor activity 6
            osmolarity-sensing monoatomic cation channel activity 5
paths to the root