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Ontology Browser
Term:
G protein-coupled receptor activity (GO:0004930)
Annotations: Rat: (1948) Mouse: (747) Human: (898) Chinchilla: (228) Bonobo: (649) Dog: (1250) Squirrel: (1040) Pig: (1736)
Parent Terms Term With Siblings Child Terms
acetylcholine receptor activity +   
apolipoprotein A-I receptor activity  
axon guidance receptor activity  
collagen receptor activity +   
complement receptor activity +   
cytokine receptor activity +   
cytokinin receptor activity +  
death receptor activity +   
G protein-coupled receptor activity +   
Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
GABA receptor activity +   
glutamate receptor activity +   
hedgehog receptor activity  
ICAM-3 receptor activity  
immunoglobulin receptor activity +   
latrotoxin receptor activity  
mechanoreceptor activity 
MHC class I receptor activity +   
MHC class Ib receptor activity +   
MHC class II receptor activity  
netrin receptor activity +   
neuregulin receptor activity  
neurotensin receptor activity, non-G protein-coupled  
non-tyrosine kinase fibroblast growth factor receptor activity  
nucleotide receptor activity +   
olfactory receptor activity +   
opsonin receptor activity +   
osmosensor activity +   
reelin receptor activity  
semaphorin receptor activity  
serotonin receptor activity +   
sulfonylurea receptor activity  
taste receptor activity +   
tiggrin receptor activity 
transmembrane receptor protein kinase activity +   
transmembrane receptor protein phosphatase activity +   
Wnt receptor activity  
 bioactive lipid receptor activity +   
 cannabinoid receptor activity  
 choriogonadotropin hormone receptor activity  
 corticotrophin-releasing factor receptor activity  
 ecdysis-triggering hormone receptor activity 
 G protein-coupled adenosine receptor activity  
 G protein-coupled amine receptor activity +   
 G protein-coupled bile acid receptor activity  
 G protein-coupled chemoattractant receptor activity +   
 G protein-coupled chemorepellent receptor activity 
 G protein-coupled cytokinin receptor activity 
 G protein-coupled estrogen receptor activity  
 G protein-coupled folate receptor activity 
 G protein-coupled GABA receptor activity  
 G protein-coupled glucose receptor activity 
 G protein-coupled glutamate receptor activity +   
 G protein-coupled neurotransmitter receptor activity +   
 G protein-coupled nucleotide receptor activity 
 G protein-coupled olfactory receptor activity  
 G protein-coupled opioid receptor activity +   
 G protein-coupled peptide receptor activity +   
 G protein-coupled photoreceptor activity  
 G protein-coupled purinergic nucleotide receptor activity +   
 G protein-coupled pyrimidinergic nucleotide receptor activity +   
 G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential +   
 gastric inhibitory peptide receptor activity  
 gonadotropin-releasing hormone receptor activity  
 GPCR taste receptor activity +  
 growth hormone secretagogue receptor activity  
 growth hormone-releasing hormone receptor activity  
 icosanoid receptor activity +   
 luteinizing hormone receptor activity  
 mast cell secretagogue receptor activity  
 melanin-concentrating hormone receptor activity  
 melatonin receptor activity  
 nicotinic acid receptor activity  
 parathyroid hormone receptor activity  
 pheromone receptor activity +   
 pituitary adenylate cyclase-activating polypeptide receptor activity  
 platelet activating factor receptor activity  
 prosaposin receptor activity  
 secretin receptor activity  
 thyroid-stimulating hormone receptor activity  
 thyrotropin-releasing hormone receptor activity  
 vasoactive intestinal polypeptide receptor activity  

Synonyms
Exact Synonyms: G protein linked receptor activity ;   GPCR activity ;   ligand-dependent GPCR activity
Narrow Synonyms: EBV-induced receptor ;   Epstein-Barr Virus-induced receptor activity ;   G-protein coupled receptor activity, unknown ligand ;   Mas proto-oncogene receptor activity ;   RDC1 receptor activity ;   SREB receptor ;   orphan G protein coupled receptor activity ;   orphan GPCR activity ;   super conserved receptor expressed in brain receptor activity
Alternate IDs: GO:0001622 ;   GO:0001623 ;   GO:0001624 ;   GO:0001625 ;   GO:0016526
Xrefs: Wikipedia:GPCR ;   reactome:R-HSA-114552 "G12/13 activation by PAR" ;   reactome:R-HSA-114558 "Gq activation by PAR" ;   reactome:R-HSA-167408 "The high affinity receptor complex binds to G-protein"
Definition Sources: GOC:bf, http://www.iuphar-db.org, Wikipedia:GPCR

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