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ONTOLOGY REPORT - ANNOTATIONS

Term:alpha-1,4-glucosidase activity
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Accession:GO:0004558 term browser browse the term
Definition:Catalysis of the hydrolysis of terminal, non-reducing alpha-(1->4)-linked alpha-D-glucose residues with release of alpha-D-glucose.
Synonyms:broad_synonym: lysosomal alpha-glucosidase activity
 related_synonym: acid maltase activity;   alpha-D-glucosidase activity;   alpha-D-glucoside glucohydrolase activity;   alpha-glucopyranosidase activity;   alpha-glucosidase II;   alpha-glucoside hydrolase activity;   glucoinvertase activity;   glucosidoinvertase activity;   glucosidosucrase activity;   maltase-glucoamylase activity
 alt_id: GO:0004562;   GO:0016982
 xref: EC:3.2.1.20;   MetaCyc:MALTODEXGLUCOSID-RXN;   Reactome:R-HSA-5659879 "Defective SI does not hydrolyze iMal";   Reactome:R-HSA-5659899 "Defective SI does not hydrolyze maltotriose";   Reactome:R-HSA-5659922 "Defective SI does not hydrolyze Mal";   reactome:R-HSA-189053 "Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose";   reactome:R-HSA-189102 "maltose + H2O => 2 D-glucose (maltase-glucoamylase)";   reactome:R-HSA-191101 "maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase)";   reactome:R-HSA-191108 "maltose + H2O => 2 D-glucose (sucrase-isomaltase)";   reactome:R-HSA-191116 "maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase)";   reactome:R-HSA-5659861 "isomaltose + H2O => 2 D-glucose (sucrase-isomaltase)"


show annotations for term's descendants           Sort by:
alpha-1,4-glucosidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GAA alpha glucosidase enables ISO
IEA		 RGD
Ensembl
TreeGrafter		 PMID:2193931 PMID:8702598 PMID:8710802 GO_REF:0000107 GO_REF:0000118 RGD:1599504 RGD:1599506 RGD:1625498 NCBI chr17:74,188,296...74,206,593
Ensembl chr17:79,723,699...79,741,839 		JBrowse link
G LOC100984344 calpain-3 enables IEA TreeGrafter GO_REF:0000118 NCBI chr15:21,227,371...21,372,406
Ensembl chr15:39,476,302...39,528,820
Ensembl chr15:39,476,302...39,528,820 		JBrowse link
G MGAM maltase-glucoamylase enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:133,929,152...134,028,684
Ensembl chr 7:146,398,798...146,498,714 		JBrowse link
G MGAM2 maltase-glucoamylase 2 (putative) enables IEA TreeGrafter GO_REF:0000118 NCBI chr 7:134,033,704...134,146,212
Ensembl chr 7:146,509,175...146,616,397 		JBrowse link
G SI sucrase-isomaltase enables IEA TreeGrafter GO_REF:0000118 NCBI chr 3:161,961,038...162,104,054
Ensembl chr 3:170,057,750...170,154,502 		JBrowse link
maltose alpha-glucosidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC3A1 solute carrier family 3 member 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chr2A:44,371,328...44,419,611
Ensembl chr2A:45,307,885...45,355,386 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 17494
    catalytic activity 5388
      hydrolase activity 2314
        hydrolase activity, acting on glycosyl bonds 129
          hydrolase activity, hydrolyzing O-glycosyl compounds 100
            glucosidase activity 15
              alpha-glucosidase activity 8
                alpha-1,4-glucosidase activity 6
                  maltose alpha-glucosidase activity 1
paths to the root