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Gene: SI (sucrase-isomaltase) Pan paniscus

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Symbol:

Name:

sucrase-isomaltase

RGD ID:

11702913

Description:

ENCODES a protein that exhibits beta-fructofuranosidase activity (ortholog); oligo-1,6-glucosidase activity (ortholog); INVOLVED IN carbohydrate utilization (ortholog); intestinal epithelial cell maturation (ortholog); response to cortisone (ortholog); PARTICIPATES IN congenital sucrase-isomaltase deficiency pathway; glycogen storage disease type III pathway; glycogen storage disease type IV pathway; ASSOCIATED WITH colitis (ortholog); congenital sucrase-isomaltase deficiency (ortholog); exocrine pancreatic insufficiency (ortholog); FOUND IN apical plasma membrane (ortholog); brush border (ortholog); brush border membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

sucrase-isomaltase, intestinal

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SI (sucrase-isomaltase)	NCBI	Ortholog
Mus musculus (house mouse):	Sis (sucrase isomaltase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Si (sucrase-isomaltase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Si (sucrase-isomaltase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SI (sucrase-isomaltase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Si (sucrase-isomaltase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SI (sucrase-isomaltase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SI (sucrase-isomaltase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Si (sucrase-isomaltase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	162,877,001 - 162,976,815 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	162,881,729 - 162,981,543 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	161,961,038 - 162,104,054 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	170,057,282 - 170,156,983 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	170,057,750 - 170,154,502 (-)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

colitis (ISO)

congenital sucrase-isomaltase deficiency (ISO)

exocrine pancreatic insufficiency (ISO)

Experimental Diabetes Mellitus (ISO)

genetic disease (ISO)

Insulin Resistance (ISO)

prostate cancer (ISO)

Reperfusion Injury (ISO)

Starvation (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

carbohydrate metabolic process (IEA)

carbohydrate utilization (ISO)

intestinal epithelial cell maturation (ISO)

response to cortisone (ISO)

response to food (ISO)

response to fructose (ISO)

response to glucocorticoid (ISO)

response to insulin (ISO)

response to muscle activity (ISO)

response to nutrient (ISO)

response to peptide hormone (ISO)

response to starvation (ISO)

response to sucrose (ISO)

response to triglyceride (ISO)

response to vitamin A (ISO)

sucrose catabolic process (IEA)

Cellular Component

apical plasma membrane (IEA,ISO)

brush border (ISO)

brush border membrane (ISO)

endoplasmic reticulum (ISO)

Golgi cisterna (ISO)

membrane (IEA)

microvillus membrane (ISO)

multivesicular body (ISO)

nuclear envelope (ISO)

vesicle (ISO)

Molecular Function

alpha-1,4-glucosidase activity (IEA)

alpha-glucosidase activity (IEA)

beta-fructofuranosidase activity (ISO)

carbohydrate binding (IEA)

catalytic activity (IEA)

hydrolase activity, acting on glycosyl bonds (IEA)

hydrolase activity, hydrolyzing O-glycosyl compounds (IEA)

oligo-1,6-glucosidase activity (IEA,ISO)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

congenital sucrase-isomaltase deficiency pathway (ISO)

glycogen storage disease type III pathway (ISO)

glycogen storage disease type IV pathway (ISO)

glycogen storage disease type VI pathway (ISO)

starch and sucrose metabolic pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

SI
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	162,877,001 - 162,976,815 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	162,881,729 - 162,981,543 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	161,961,038 - 162,104,054 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	170,057,282 - 170,156,983 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	170,057,750 - 170,154,502 (-)	Ensembl	panpan1.1		panPan2

SI
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	164,978,898 - 165,090,232 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	164,978,898 - 165,078,496 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	164,696,686 - 164,796,284 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	166,179,380 - 166,278,976 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	3	166,179,388 - 166,278,984	NCBI
Celera	3	163,095,850 - 163,195,264 (-)	NCBI		Celera
Cytogenetic Map	3	q26.1	NCBI
HuRef	3	162,066,552 - 162,166,109 (-)	NCBI		HuRef
CHM1_1	3	164,659,546 - 164,759,127 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	3	167,761,814 - 167,873,135 (-)	NCBI		T2T-CHM13v2.0

Sis
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	72,795,890 - 72,875,196 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	72,795,890 - 72,875,196 (-)	Ensembl		GRCm39 Ensembl
GRCm38	3	72,888,557 - 72,967,863 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	72,888,557 - 72,967,863 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	72,692,482 - 72,770,788 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	72,976,489 - 73,055,789 (-)	NCBI		MGSCv36	mm8
Celera	3	73,012,488 - 73,086,863 (-)	NCBI		Celera
Cytogenetic Map	3	E3	NCBI
cM Map	3	32.59	NCBI

Si
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	159,804,568 - 159,884,902 (-)	NCBI		GRCr8
mRatBN7.2	2	157,505,893 - 157,586,228 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	157,506,342 - 157,585,260 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	164,628,371 - 164,709,000 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	162,678,862 - 162,759,493 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	157,311,634 - 157,392,265 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	170,220,794 - 170,301,348 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	170,221,245 - 170,301,348 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	189,563,145 - 189,643,699 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	163,520,975 - 163,601,280 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	163,470,937 - 163,551,243 (-)	NCBI
Celera	2	151,764,945 - 151,845,208 (-)	NCBI		Celera
RH 3.4 Map	2	1027.6	RGD
Cytogenetic Map	2	q32	NCBI

Si
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955448	14,685,963 - 14,777,338 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955448	14,686,315 - 14,777,298 (-)	NCBI	ChiLan1.0	ChiLan1.0

SI
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	34	30,284,869 - 30,373,749 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	34	30,284,858 - 30,373,780 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	34	39,346,430 - 39,434,804 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	34	30,347,263 - 30,435,400 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	34	30,346,966 - 30,434,636 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	34	30,290,443 - 30,378,872 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	34	30,241,911 - 30,330,433 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	34	30,511,922 - 30,599,883 (-)	NCBI		UU_Cfam_GSD_1.0

Si
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	96,367,610 - 96,445,267 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936707	1,153,538 - 1,228,220 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936707	1,153,538 - 1,228,220 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SI
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	104,296,283 - 104,379,478 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	104,296,281 - 104,379,558 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	112,716,702 - 112,812,308 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SI
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	15	24,480,060 - 24,582,468 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	15	24,482,865 - 24,582,394 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666063	33,458,175 - 33,557,570 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Si
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624730	42,984,431 - 43,112,819 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624730	42,984,277 - 43,112,819 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003817701	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000032550 ⟹ ENSPPAP00000009903

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	3	170,057,750 - 170,154,502 (-)	Ensembl

RefSeq Acc Id:

XM_003817701 ⟹ XP_003817749

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	2	162,877,001 - 162,976,815 (-)	NCBI
NHGRI_mPanPan1	3	162,881,729 - 162,981,543 (-)	NCBI
Mhudiblu_PPA_v0	3	161,961,038 - 162,104,054 (-)	NCBI
PanPan1.1	3	170,057,282 - 170,156,983 (-)	NCBI

Sequence:

show sequence

TTATTTTGGCAGCCTTATCCAAGTCTGGTACAACATAGCAAAGAGAACAGGCTATGAAATAAGA
TGGCAAGAAAGAAATTTAGTGGATTGGAAATCTCTCTGATTGTCCTCTTTGTCATAGTTACTAT
AATAGCTATTGCCTTAATTGTTGTTTTAGCAACTAAAACACCTGCTGTTGATGAAATTAGTGAT
TCTACTTCAACTCCAGCTACTAATCGTGTGACTACAAATCCTGATTCAGGAAAATGTCCAAATG
TGTTAAATGATCCTGTCAATGTGAGAATAAACTGCATTCCAGAACAATTCCCAACAGAGGGAAT
TTGTGCACAGAGAGGCTGCTGCTGGAGGCCGTGGAATGACTCTCTTATTCCTTGGTGCTTCTTC
GTTGATAATCATGGTTATAACGTTCAAGACATGACAACAACAAGTATTGGAGTTGAAGCCAAAT
TAAACAGGATACCTTCACCTACACTATTTGGAAATGACATCAACAGTGTTCTCTTCACAACTCA
AAATCAGACACCCAATCGTTTCCGGTTCAAGATTACTGATCCAAATAATAGAAGATATGAAGTT
CCTCATCAGTATGTACAAGAGTTTACTGGACCCACAGTTTCTGATACATTGTATGATGTGAAGG
TTGCCCAAAACCCATTTAGCATCCAAGTTATTAGGAAAAGCAATGGTAAAACTTTGTTTGACAC
CAGCATTGGTCCCTTAGTGTACTCTGACCAGTACTTGCAGCTCTCAACCCGTCTTCCAAGTGAT
TATATTTATGGTATTGGAGAACAGGTTCATAAGAGATTTCGTCATGATTTATCCTGGAAAACAT
GGCCAATTTTTACTCGAGACCAACTTCCTGGTGATAATAATAATAATTTATACGGCCATCAAAC
ATTCTTTATGTGTATTGAAGATACATCTGGAAAGTCATTCGGTGTTTTTTTAATGAATAGCAAT
GCAATGGAGATTTTTATCCAGCCTACACCAATAGTAACATATAGAGTTACCGGTGGCATTCTGG
ATTTTTACATCCTTCTAGGAGATACACCAGAACAAGTAGTTCAACAGTATCAACAGCTTGTTGG
ACTACCAGCAATGCCAGCATATTGGAATCTTGGATTCCAACTAAGTCGCTGGAATTATAAGTCA
CTAGATGTAGTGAAAGAAGTGGTAAGGAGAAACCGGGAAGCTGGCATACCATTTGATACACAGG
TCACTGATATTGACTACATGGAAGACAAGAAAGACTTTACTTATGATCAAGTTGCATTTAACGG
ACTCCCTCAATTTGTGCAAGATTTGCATGACCATGGACAGAAATATGTCATCATCTTGGACCCT
GCAATTTCCATAGGTCGACGTGCCAATGGAACAACATATGCAACCTATGAGAGGGGAAACACAC
AACATGTGTGGATAAATGAGTCAGATGGAAGTACACCAATTATTGGAGAGGTATGGCCAGGATT
AACAGTATACCCTGATTTCACTAATCCAAACTGCATTGATTGGTGGGCAAATGAATGCAGTATT
TTCCATCAGGAAGTGCAATATGATGGACTTTGGATTGACATGAATGAAGTTTCCAGCTTTATTC
AAGGTTCAACAAAAGGATGTAATGTAAACAAATTGAATTATCCACCGTTTACTCCTGATATTCT
TGACAAACTCATGTATTCCAAAACAATTTGCATGGATGCTGTGCAGAACTGGGGTAAACAGTAT
GATGTTCACAGCCTCTATGGATACAGCATGGCTATAGCCACAGAGCAAGCTGTACAAAAAGTTT
TTCCTAATAAGAGAAGCTTCATTCTTACCCGCTCAACATTTGCTGGATCTGGAAGACATGCTGC
ACATTGGTTAGGAGACAATACTGCTTCATGGGAACAAATGGAATGGTCTATAACTGGAATGCTG
GAGTTCAGTTTGTTTGGAATACCTTTGGTTGGAGCAGACATCTGTGGATTTGTGGCTGAAACCA
CAGAAGAACTTTGCAGAAGATGGATGCAACTTGGGGCATTTTATCCATTTTCCAGAAACCATAA
TTCTGACGGATATGAACATCAGGATCCTGCATTTTTTGGGCAGAATTCACTTTTGGTTAAATCA
TCAAGGCAGTATTTAACTATTCGCTACACCTTATTACCCTTCCTCTACACTCTGTTTTATAAAG
CCCATGTGTTTGGAGAAACAGTAGCAAGACCAGTTCTTCATGAGTTTTATGAGGATACGAACAG
CTGGATTGAGGACACTGAGTTTTTGTGGGGCCCTGCATTACTTATTACTCCTGTTCTAAAACAG
GGAGCAGATACTGTGAGTGCCTACATCCCTGATGCTATTTGGTATGATTATGAATCTGGTGCAA
AAAGGCCATGGAGGAAACAACGGGTTGATATGTATCTTCCAGCAGACAAAATAGGATTACATCT
TAGAGGAGGTTATATCATCCCCATTCAAGAACCAGATGTAACAACAACAGCAAGCCGTAAGAAT
CCTCTAGGACTTATAGTCGCGTTAGGTGAAAACAACACAGCCAAAGGAGACTTTTTCTGGGATG
ATGGAGAAACTAAAGATACCATACAAAATGGCAACTACATATTATACACATTTTCAGTTTCTAA
TAACACATTAGATATTGTGTGCACACATTCATCATATCAGGAAGGAACTACCTTAGCATTTCAG
ACTGTAAAAATCCTTGGGTTGACAGACAGTGTTACAGAAGTTAGAGTGGCGGAAAATAATCAAC
CAATGAACGCTCATTCCAATTTCACTTATGATGCTTCTAACCAGGTTCTCCTAATTGCAGATCT
CAAACTTAATCTTGGAAGAAACTTTAGTGTTCAATGGAATCAAATTTTCTCAGAAAATGAAAGA
TTTAATTGTTATCCAGATGCAGATTTGGCAACTGAACAAAAGTGCACACAACGTGGCTGTGTAT
GGCGAACGGGTTCTTCTCTATCGAAAGCACCTGAGTGTTACTTTCCCAGACAAGATAACTCTTA
TTCAGTCAACTCAGCTCGCTATTCATCCATGGGTATAACAGCTGACCTCCAACTAAATACTGCA
AATGCCAGAATAAAGTTACCTTCTGACCCCATCTCAACTCTTCGTGTGGAGGTGAAATATCACA
AAAATGATATGTTGCAGTTTAAGATTTATGATCCCCAAAAGAAGAGATATGAAGTACCAGTACC
GTTAAACATTCCAACCACCCCAATAAGTACTTATGAAGACAGACTTTATGATGTGGAAATCAAG
GAAAATCCTTTTGGCATCCAGATTCGACGGAGAAGCAGTGGAAGAGTCATTTGGGATTCTTGGC
TGCCTGGATTTGCTTTTAATGACCAGTTCATTCAAATATCGACTCGCCTGCCATCAGAATATAT
ATATGGTTTTGGGGAAGTGGAACATACAGCATTTAAGCGAGATCTGAACTGGAATACTTGGGGA
ATGTTCACAAGAGACCAACCCCCTGGTTACAAACTTAATTCCTATGGATTTCATCCCTATTACA
TGGCTCTGGAAGAGGAGGGCAATGCTCATGGTGTTTTCTTACTCAACAGCAATGCAATGGATGT
TACATTCCAGCCAACTCCTGCTCTAACTTACCGTACAGTTGGAGGGATCTTGGATTTTTATATG
TTTTTGGGCCCAACTCCAGAAGTTGCAACAAAGCAATACCATGAAGTAATTGGCCATCCAGTCA
TGCCAGCTTATTGGGCTTTGGGATTCCAATTATGTCGTTATGGATATGCAAATACTTCAGAGGT
TCGGGAATTATATGACGCTATGGTGGCTGCTAACATCCCCTATGATGTTCAGTACACAGACATT
GACTACATGGAAAGGCAGCTAGACTTTACAATTGGTGAAGCATTCCAGGACCTTCCTCAGTTTG
TTGACAAAATAAGAGGAGAAGGAATGAGATACATTATTATCCTGGATCCAGCAATTTCAGGAAA
TGAAACAAAGACTTACCCTGCATTTGAAAGAGGACAGCAGAATGATGTCTTTGTCAAATGGCCA
AACACCAATGACATTTGTTGGGCAAAGGTTTGGCCAGATTTGCCCAACATAACAATAGATAAAA
CTCTAACGGAAGATGAAGCTGTTAATGCTTCCAGAGCTCATGTAGCTTTCCCAGATTTCTTCAG
GACTTCCACAGCAGAGTGGTGGGCCAGAGAAATTGTGGACTTTTACAATGAAAAGATGAAGTTT
GATGGTTTGTGGATTGATATGAATGAGCCATCAAGTTTTGTAAATGGAACAACTACTAATCAAT
GCAGAAATGACGAACTAAATTATCCACCTTATTTCCCAGAACTCACAAAAAGAACCGATGGATT
ACATTTCAGAACAATTTGCATGGAAGCTGAGCAGATTCTTAGTGATGGAACATCAGTTTTACAT
TACGATGTTCACAATCTCTATGGATGGTCACAGATGAAACCTACTCATGATGCATTGCAGAAGA
CAACTGGAAAAAGAGGGATTGTAATTTCTCGTTCCACGTATCCTACTAGTGGACGATGGGGAGG
ACACTGGCTTGGAGACAACTATGCACGATGGGACAACATGGACAAATCAATCATTGGTATGATG
GAATTTAGTCTGTTTGGAATATCATATACTGGAGCAGACATCTGTGGTTTTTTCAACAACTCAG
AATATCATCTCTGTACCCGCTGGATGCAACTTGGAGCATTTTATCCATACTCAAGGAATCACAA
CATTGCAAATACTAGAAGACAAGATCCCGCTTCCTGGAATGAAACTTTTGCTGAAATGTCAAGG
AATATTCTAAATATTAGATACACCTTATTGCCCTATTTCTACACACAAATGCATGAAATTCATG
CTAATGGTGGCACTGTTATCCGACCCCTTTTGCATGAGTTCTTTGATGAAAAACCAACCTGGGA
TATATTCAAGCAGTTCTTATGGGGTCCAGCATTTATGGTTACCCCAGTACTGGAACCTTATGTT
CAAACTGTAAATGCCTACGTCCCCAATGCTCGGTGGTTTGACTACCATACAGGCAAAGATATTG
GCGTCAGAGGACAATTTCAAACATTTAATGCTTCTTATGACACAATAAACCTACATGTCCGTGG
TGGTCACATCCTACCATGTCAAGAGCCAGCTCAAAACACATTTTACAGTCGACAAAAACACATG
AATCTCATTGTTGCTGCAGATGACAATCAGACGGCACAGGGTTCTCTGTTTTGGGATGATGGAG
AGAGTATAGACACCTATGAAAGAGACCTATATTTATCTGTACAATTTAATTTAAACCAGACCAC
CTTAACAAGCACTATATTGAAGAGAGGTTACATAAATAAAAGTGAAACGAGGCTTGGGTCCGTT
CATGTATGGGGGAAAGGAACTACTCCTGTCAATGCAGTTACTCTAACGTATAACGGAAATACAA
ATTCGCTTCCTTTTAATGAAGACAGTACCAACATGATATTACATATTGATCTCACCACACACAA
TGTTACTCTAGAAGAACCAATAGAAATCAACTGGTCATGAAGATCACCATCAATTTTAGTTGTC
AATGGGAAAAAACACCAGGATTTAAGTTTCACAGCACTTACAACTTTCCCTCTTCACTTGGTTA
TTGTACTCTACAAAATATAGCTTTCATAACATCGAAAAGCTATTTTGTAGCATACATCAATGAT
AATGCTAATTTTATAATAGTAATGTGACTTGGATTCAATTTTAAGGCATATTTAACAAATTTGA
ATAGCCCTATTTATCCTTGTTAAGTATCAGCTACAATTGTAAACTAGTTACTAAATATGTATGT
AAATAGCTAAGATATAATTTAAACGTGATTTTTAAATTAAATAAAATTTTTATGTAATTATAAA
TTATATACTATATTTTTCTCAACGTTTAGCAGATTTAAGATATGTAACAACAATTATTTGAAGA
TTTAATTATTTCTTAGTATGTACATTTAATTAGAAAAAGAGAATAAAAAATGTAAGTGTA

hide sequence

Protein Sequences


Protein RefSeqs	XP_003817749	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000009903.1

RefSeq Acc Id:

XP_003817749 ⟸ XM_003817701

- UniProtKB:

A0A2R9A1Y1 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MARKKFSGLEISLIVLFVIVTIIAIALIVVLATKTPAVDEISDSTSTPATNRVTTNPDSGKCPN
VLNDPVNVRINCIPEQFPTEGICAQRGCCWRPWNDSLIPWCFFVDNHGYNVQDMTTTSIGVEAK
LNRIPSPTLFGNDINSVLFTTQNQTPNRFRFKITDPNNRRYEVPHQYVQEFTGPTVSDTLYDVK
VAQNPFSIQVIRKSNGKTLFDTSIGPLVYSDQYLQLSTRLPSDYIYGIGEQVHKRFRHDLSWKT
WPIFTRDQLPGDNNNNLYGHQTFFMCIEDTSGKSFGVFLMNSNAMEIFIQPTPIVTYRVTGGIL
DFYILLGDTPEQVVQQYQQLVGLPAMPAYWNLGFQLSRWNYKSLDVVKEVVRRNREAGIPFDTQ
VTDIDYMEDKKDFTYDQVAFNGLPQFVQDLHDHGQKYVIILDPAISIGRRANGTTYATYERGNT
QHVWINESDGSTPIIGEVWPGLTVYPDFTNPNCIDWWANECSIFHQEVQYDGLWIDMNEVSSFI
QGSTKGCNVNKLNYPPFTPDILDKLMYSKTICMDAVQNWGKQYDVHSLYGYSMAIATEQAVQKV
FPNKRSFILTRSTFAGSGRHAAHWLGDNTASWEQMEWSITGMLEFSLFGIPLVGADICGFVAET
TEELCRRWMQLGAFYPFSRNHNSDGYEHQDPAFFGQNSLLVKSSRQYLTIRYTLLPFLYTLFYK
AHVFGETVARPVLHEFYEDTNSWIEDTEFLWGPALLITPVLKQGADTVSAYIPDAIWYDYESGA
KRPWRKQRVDMYLPADKIGLHLRGGYIIPIQEPDVTTTASRKNPLGLIVALGENNTAKGDFFWD
DGETKDTIQNGNYILYTFSVSNNTLDIVCTHSSYQEGTTLAFQTVKILGLTDSVTEVRVAENNQ
PMNAHSNFTYDASNQVLLIADLKLNLGRNFSVQWNQIFSENERFNCYPDADLATEQKCTQRGCV
WRTGSSLSKAPECYFPRQDNSYSVNSARYSSMGITADLQLNTANARIKLPSDPISTLRVEVKYH
KNDMLQFKIYDPQKKRYEVPVPLNIPTTPISTYEDRLYDVEIKENPFGIQIRRRSSGRVIWDSW
LPGFAFNDQFIQISTRLPSEYIYGFGEVEHTAFKRDLNWNTWGMFTRDQPPGYKLNSYGFHPYY
MALEEEGNAHGVFLLNSNAMDVTFQPTPALTYRTVGGILDFYMFLGPTPEVATKQYHEVIGHPV
MPAYWALGFQLCRYGYANTSEVRELYDAMVAANIPYDVQYTDIDYMERQLDFTIGEAFQDLPQF
VDKIRGEGMRYIIILDPAISGNETKTYPAFERGQQNDVFVKWPNTNDICWAKVWPDLPNITIDK
TLTEDEAVNASRAHVAFPDFFRTSTAEWWAREIVDFYNEKMKFDGLWIDMNEPSSFVNGTTTNQ
CRNDELNYPPYFPELTKRTDGLHFRTICMEAEQILSDGTSVLHYDVHNLYGWSQMKPTHDALQK
TTGKRGIVISRSTYPTSGRWGGHWLGDNYARWDNMDKSIIGMMEFSLFGISYTGADICGFFNNS
EYHLCTRWMQLGAFYPYSRNHNIANTRRQDPASWNETFAEMSRNILNIRYTLLPYFYTQMHEIH
ANGGTVIRPLLHEFFDEKPTWDIFKQFLWGPAFMVTPVLEPYVQTVNAYVPNARWFDYHTGKDI
GVRGQFQTFNASYDTINLHVRGGHILPCQEPAQNTFYSRQKHMNLIVAADDNQTAQGSLFWDDG
ESIDTYERDLYLSVQFNLNQTTLTSTILKRGYINKSETRLGSVHVWGKGTTPVNAVTLTYNGNT
NSLPFNEDSTNMILHIDLTTHNVTLEEPIEINWS

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Ensembl Acc Id:

ENSPPAP00000009903 ⟸ ENSPPAT00000032550

Protein Domains

P-type

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000028177	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000032550.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.1180	UniProtKB/TrEMBL
	4.10.110.10	UniProtKB/TrEMBL
	Glycosidases	UniProtKB/TrEMBL
	glycosyl hydrolase (family 31)	UniProtKB/TrEMBL
InterPro	Gal_mutarotase_sf_dom	UniProtKB/TrEMBL
	Glyco_hydro_31	UniProtKB/TrEMBL
	Glyco_hydro_31_AS	UniProtKB/TrEMBL
	Glyco_hydro_31_C	UniProtKB/TrEMBL
	Glyco_hydro_31_CS	UniProtKB/TrEMBL
	Glyco_hydro_31_N_dom	UniProtKB/TrEMBL
	Glyco_hydro_b	UniProtKB/TrEMBL
	Glycoside_hydrolase_SF	UniProtKB/TrEMBL
	P_trefoil_CS	UniProtKB/TrEMBL
	P_trefoil_dom	UniProtKB/TrEMBL
	P_trefoil_dom_sf	UniProtKB/TrEMBL
KEGG Report	pps:100973298	UniProtKB/TrEMBL
NCBI Gene	SI	ENTREZGENE
PANTHER	ALPHA-GLUCOSIDASE	UniProtKB/TrEMBL
	P-TYPE DOMAIN-CONTAINING PROTEIN	UniProtKB/TrEMBL
Pfam	Gal_mutarotas_2	UniProtKB/TrEMBL
	Glyco_hydro_31	UniProtKB/TrEMBL
	Glyco_hydro_31_3rd	UniProtKB/TrEMBL
	Trefoil	UniProtKB/TrEMBL
PROSITE	GLYCOSYL_HYDROL_F31_1	UniProtKB/TrEMBL
	GLYCOSYL_HYDROL_F31_2	UniProtKB/TrEMBL
	P_TREFOIL_1	UniProtKB/TrEMBL
	P_TREFOIL_2	UniProtKB/TrEMBL
SMART	SM00018	UniProtKB/TrEMBL
Superfamily-SCOP	Glycosyl hydrolase domain	UniProtKB/TrEMBL
	SSF51445	UniProtKB/TrEMBL
	SSF57492	UniProtKB/TrEMBL
	SSF74650	UniProtKB/TrEMBL
UniProt	A0A2R9A1Y1	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB