MGAM (maltase-glucoamylase) - Rat Genome Database

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Gene: MGAM (maltase-glucoamylase) Pan paniscus
Analyze
Symbol: MGAM
Name: maltase-glucoamylase
RGD ID: 11694373
Description: ENCODES a protein that exhibits alpha-1,4-glucosidase activity (inferred); alpha-glucosidase activity (inferred); amylase activity (inferred); INVOLVED IN carbohydrate metabolic process (inferred); dextrin catabolic process (inferred); maltose catabolic process (inferred); PARTICIPATES IN congenital sucrase-isomaltase deficiency pathway; glycogen storage disease type III pathway; glycogen storage disease type IV pathway; ASSOCIATED WITH Hereditary Pancreatitis (ortholog); RASopathy (ortholog); Sengers syndrome (ortholog); FOUND IN apical plasma membrane (inferred); membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC100969261; maltase-glucoamylase (alpha-glucosidase); maltase-glucoamylase, intestinal; maltase-glucoamylase, intestinal-like
RGD Orthologs
Human
Mouse
Rat
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26178,776,569 - 178,886,094 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1730,785,638 - 30,896,349 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07133,929,152 - 134,028,684 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17146,398,798 - 146,499,566 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7146,398,798 - 146,498,714 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
MGAM
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26178,776,569 - 178,886,094 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1730,785,638 - 30,896,349 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07133,929,152 - 134,028,684 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17146,398,798 - 146,499,566 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7146,398,798 - 146,498,714 (+)Ensemblpanpan1.1panPan2
MGAM
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387141,986,518 - 142,106,747 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7141,907,813 - 142,106,747 (+)EnsemblGRCh38hg38GRCh38
GRCh377141,695,679 - 141,806,547 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367141,342,148 - 141,453,016 (+)NCBINCBI36Build 36hg18NCBI36
Build 347141,148,862 - 141,259,730NCBI
Celera7136,417,024 - 136,479,472 (+)NCBICelera
Cytogenetic Map7q34NCBI
HuRef7135,992,049 - 136,101,675 (+)NCBIHuRef
CHM1_17141,629,942 - 141,740,779 (+)NCBICHM1_1
T2T-CHM13v2.07143,304,624 - 143,421,799 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27141,033,874 - 141,144,746 (+)NCBI
Mgam
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39640,605,765 - 40,746,057 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl640,605,765 - 40,746,057 (+)EnsemblGRCm39 Ensembl
GRCm38640,628,831 - 40,769,123 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl640,628,831 - 40,769,123 (+)EnsemblGRCm38mm10GRCm38
MGSCv37640,578,830 - 40,719,122 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36640,628,670 - 40,698,729 (+)NCBIMGSCv36mm8
Celera640,615,341 - 40,755,282 (+)NCBICelera
Cytogenetic Map6B1NCBI
cM Map618.82NCBI
Mgam2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8470,590,706 - 70,682,462 (+)NCBIGRCr8
mRatBN7.2469,624,024 - 69,715,782 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl469,637,799 - 69,683,742 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0469,018,592 - 69,114,027 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl468,849,033 - 68,996,961 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04133,815,579 - 133,882,511 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4468,404,350 - 68,492,162 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1468,474,973 - 68,767,490 (+)NCBI
Celera464,614,198 - 64,702,998 (+)NCBICelera
Cytogenetic Map4q23NCBI
MGAM
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1167,124,343 - 7,218,035 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl167,125,114 - 7,260,241 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha167,983,615 - 8,077,307 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0167,045,872 - 7,139,573 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl167,045,909 - 7,120,389 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1166,999,418 - 7,091,186 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0166,841,628 - 6,935,377 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0166,909,377 - 7,003,078 (-)NCBIUU_Cfam_GSD_1.0
Mgam
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511813,297,685 - 13,452,233 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365925,778,487 - 5,841,770 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MGAM
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl187,871,532 - 7,970,169 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1187,871,529 - 7,997,137 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2188,315,646 - 8,340,414 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MGAM
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121110,684,981 - 110,837,138 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl21110,697,544 - 110,837,133 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660727,372,472 - 7,534,516 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mgam
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476521,943,138 - 22,130,381 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476521,936,667 - 22,131,182 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Ensembl Acc Id: ENSPPAT00000029200   ⟹   ENSPPAP00000007128
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl7146,398,798 - 146,498,714 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000029212   ⟹   ENSPPAP00000007138
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl7146,398,798 - 146,498,714 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000029218   ⟹   ENSPPAP00000007141
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl7146,398,798 - 146,498,714 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000029220   ⟹   ENSPPAP00000007143
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl7146,398,798 - 146,498,714 (+)Ensembl
RefSeq Acc Id: XM_034965120   ⟹   XP_034821011
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26178,776,569 - 178,886,094 (+)NCBI
NHGRI_mPanPan1730,785,638 - 30,896,349 (+)NCBI
Mhudiblu_PPA_v07133,929,152 - 134,028,684 (+)NCBI
RefSeq Acc Id: XM_055115468   ⟹   XP_054971443
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26178,786,213 - 178,886,057 (+)NCBI
NHGRI_mPanPan1730,796,468 - 30,896,315 (+)NCBI
Protein Sequences
Protein RefSeqs XP_034821011 (Get FASTA)   NCBI Sequence Viewer  
  XP_054971443 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000007128.1
  ENSPPAP00000007138.1
  ENSPPAP00000007141.1
  ENSPPAP00000007143.1
RefSeq Acc Id: XP_034821011   ⟸   XM_034965120
- Peptide Label: isoform X1
- UniProtKB: A0A2R8ZRH5 (UniProtKB/TrEMBL),   A0A2R8ZRI3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSPPAP00000007128   ⟸   ENSPPAT00000029200
Ensembl Acc Id: ENSPPAP00000007143   ⟸   ENSPPAT00000029220
Ensembl Acc Id: ENSPPAP00000007141   ⟸   ENSPPAT00000029218
Ensembl Acc Id: ENSPPAP00000007138   ⟸   ENSPPAT00000029212
RefSeq Acc Id: XP_054971443   ⟸   XM_055115468
- Peptide Label: isoform X2
- UniProtKB: A0A2R8ZQC5 (UniProtKB/TrEMBL)
Protein Domains
P-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000026007 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000029200.1 UniProtKB/TrEMBL
  ENSPPAT00000029212.1 UniProtKB/TrEMBL
  ENSPPAT00000029218.1 UniProtKB/TrEMBL
  ENSPPAT00000029220.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.1180 UniProtKB/TrEMBL
  4.10.110.10 UniProtKB/TrEMBL
  Glycosidases UniProtKB/TrEMBL
  glycosyl hydrolase (family 31) UniProtKB/TrEMBL
InterPro Gal_mutarotase_sf_dom UniProtKB/TrEMBL
  Glyco_hydro_31 UniProtKB/TrEMBL
  Glyco_hydro_31_AS UniProtKB/TrEMBL
  Glyco_hydro_31_C UniProtKB/TrEMBL
  Glyco_hydro_31_CS UniProtKB/TrEMBL
  Glyco_hydro_31_N_dom UniProtKB/TrEMBL
  Glyco_hydro_b UniProtKB/TrEMBL
  Glycoside_hydrolase_SF UniProtKB/TrEMBL
  P_trefoil_CS UniProtKB/TrEMBL
  P_trefoil_dom UniProtKB/TrEMBL
  P_trefoil_dom_sf UniProtKB/TrEMBL
NCBI Gene MGAM ENTREZGENE
PANTHER ALPHA-GLUCOSIDASE UniProtKB/TrEMBL
  P-TYPE DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
Pfam Gal_mutarotas_2 UniProtKB/TrEMBL
  Glyco_hydro_31 UniProtKB/TrEMBL
  Glyco_hydro_31_3rd UniProtKB/TrEMBL
  Trefoil UniProtKB/TrEMBL
PROSITE GLYCOSYL_HYDROL_F31_1 UniProtKB/TrEMBL
  GLYCOSYL_HYDROL_F31_2 UniProtKB/TrEMBL
  P_TREFOIL_1 UniProtKB/TrEMBL
  P_TREFOIL_2 UniProtKB/TrEMBL
SMART SM00018 UniProtKB/TrEMBL
Superfamily-SCOP Glycosyl hydrolase domain UniProtKB/TrEMBL
  SSF51445 UniProtKB/TrEMBL
  SSF57492 UniProtKB/TrEMBL
  SSF74650 UniProtKB/TrEMBL
UniProt A0A2R8ZQC5 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8ZRH5 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8ZRI3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-05-08 MGAM  maltase-glucoamylase  LOC100969261  maltase-glucoamylase, intestinal-like  Data merged from RGD:11996190 737654 PROVISIONAL