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ONTOLOGY REPORT - ANNOTATIONS

Term:acetyl-CoA C-acetyltransferase activity
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Accession:GO:0003985 term browser browse the term
Definition:Catalysis of the reaction: 2 acetyl-CoA = CoA + acetoacetyl-CoA.
Synonyms:related_synonym: acetoacetyl-CoA thiolase activity;   acetyl coenzyme A thiolase activity
 xref: EC:2.3.1.9;   MetaCyc:ACETYL-COA-ACETYLTRANSFER-RXN;   RHEA:21036;   UM-BBD_enzymeID:e0144;   reactome:R-HSA-70844 "alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA";   reactome:R-HSA-73916 "2 acetyl-CoA <=> acetoacetyl-CoA + CoA";   reactome:R-HSA-74181 "acetoacetyl-CoA + CoA <=> 2 acetyl-CoA";   reactome:R-HSA-8848215 "ACAT2 condenses 2 Ac-CoA to form ACA-CoA"


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acetyl-CoA C-acetyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaa1a acetyl-Coenzyme A acyltransferase 1A enables TAS (PMID:11461119) MGI PMID:11461119 NCBI chr 9:119,170,113...119,179,361
Ensembl chr 9:119,168,742...119,179,365 		JBrowse link
G Acaa1b acetyl-Coenzyme A acyltransferase 1B enables IEA UniProt GO_REF:0000003 MGI:2152096 NCBI chr 9:118,977,111...118,986,149
Ensembl chr 9:118,977,091...118,986,161 		JBrowse link
G Acaa2 acetyl-CoA acyltransferase 2 enables ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr18:74,912,283...74,939,278
Ensembl chr18:74,912,268...74,939,279 		JBrowse link
G Acat1 acetyl-Coenzyme A acetyltransferase 1 enables ISO
IDA
IBA		 (PMID:12114517), (PMID:7592824) MGI
RGD
GO_Central		 PMID:2478525 PMID:7592824 PMID:12114517 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 RGD:631716 NCBI chr 9:53,491,822...53,521,650
Ensembl chr 9:53,491,822...53,521,682 		JBrowse link
G Acat2 acetyl-Coenzyme A acetyltransferase 2 enables ISO
IBA		 MGI
RGD
GO_Central		 PMID:10806397 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 RGD:2326086 NCBI chr17:13,161,929...13,179,612
Ensembl chr17:13,161,777...13,179,634 		JBrowse link
G Acat3 acetyl-Coenzyme A acetyltransferase 3 enables ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 NCBI chr17:13,142,720...13,159,482
Ensembl chr17:13,142,700...13,159,487 		JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta enables IDA (PMID:32513690) MGI PMID:32513690 NCBI chr 5:30,360,251...30,389,591
Ensembl chr 5:30,360,246...30,389,591 		JBrowse link
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Term Annotations click to browse term
  molecular_function 28831
    catalytic activity 5721
      transferase activity 2294
        acyltransferase activity 723
          acyltransferase activity, transferring groups other than amino-acyl groups 236
            C-acyltransferase activity 22
              acetyl-CoA C-acyltransferase activity 9
                acetyl-CoA C-acetyltransferase activity 7
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