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ONTOLOGY REPORT - ANNOTATIONS

Term:smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation
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Accession:GO:0003271 term browser browse the term
Definition:The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened contributing to the modulation of the frequency, rate or extent of cardioblast proliferation in the secondary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
Synonyms:exact_synonym: hedgehog signaling pathway involved in regulation of second heart field cardioblast proliferation;   hh signaling pathway involved in regulation of second heart field cardioblast proliferation;   smoothened receptor signaling pathway involved in regulation of second heart field cardioblast proliferation;   smoothened receptor signaling pathway involved in regulation of secondary heart field cardioblast proliferation;   smoothened receptor signalling pathway involved in regulation of secondary heart field cardioblast proliferation


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smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mks1 MKS transition zone complex subunit 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:4821832 (PMID:27340223)		 Ensembl
RGD		 PMID:27340223 GO_REF:0000107 NCBI chr10:72,655,921...72,667,007
Ensembl chr10:72,655,921...72,666,655 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20228
    cellular process 19289
      signal transduction 7199
        cell surface receptor signaling pathway 2842
          smoothened signaling pathway 172
            smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation 1
Path 2
Term Annotations click to browse term
  biological_process 20228
    developmental process 7076
      anatomical structure development 6578
        multicellular organism development 5302
          system development 4587
            circulatory system development 1374
              heart development 745
                heart morphogenesis 297
                  cell proliferation involved in heart morphogenesis 21
                    regulation of cell proliferation involved in heart morphogenesis 19
                      regulation of cardioblast proliferation 12
                        regulation of secondary heart field cardioblast proliferation 11
                          smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation 1
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