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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of cell proliferation involved in heart morphogenesis
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Accession:GO:2000136 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of cell proliferation involved in heart morphogenesis.



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regulation of cell proliferation involved in heart morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eng endoglin NOT|involved_in ISO (MGI:3721185|PMID:17628518) RGD PMID:17628518 MGI:3721185 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230
JBrowse link
canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctnnb1 catenin beta 1 involved_in ISO
IEA
(MGI:2446944|PMID:12464179)
GO_REF:0000107
RGD
Ensembl
PMID:12464179 GO_REF:0000107 MGI:2446944 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Lrp6 LDL receptor related protein 6 acts_upstream_of_or_within ISO MGI:2156191 (MGI:4413394|PMID:19705442) RGD PMID:19705442 MGI:4413394 NCBI chr 4:167,266,581...167,400,155
Ensembl chr 4:167,270,353...167,400,497
JBrowse link
negative regulation of cell proliferation involved in heart morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:20702560)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:20702560 GO_REF:0000024 GO_REF:0000107 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Tbx3 T-box transcription factor 3 involved_in ISO (PMID:22130515) RGD PMID:22130515 NCBI chr12:36,879,924...36,894,849
Ensembl chr12:36,881,445...36,893,708
JBrowse link
negative regulation of cell proliferation involved in heart valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISO (MGI:3851675|PMID:19409885) RGD PMID:19409885 MGI:3851675 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809
JBrowse link
G Notch1 notch receptor 1 involved_in ISO (MGI:6158728|PMID:26491108) RGD PMID:26491108 MGI:6158728 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Notch1 notch receptor 1 acts_upstream_of_or_within ISO (MGI:4438134|PMID:19620969) RGD PMID:19620969 MGI:4438134 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
positive regulation of cardioblast proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase involved_in ISO (PMID:21474815) RGD PMID:21474815 NCBI chr20:7,554,921...7,559,174
Ensembl chr20:7,554,921...7,559,174
JBrowse link
positive regulation of cell proliferation involved in heart morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp10 bone morphogenetic protein 10 involved_in IEA
ISO
GO_REF:0000107
UniProtKB:P31266 (MGI:3701380|PMID:17336907)
Ensembl
RGD
PMID:17336907 GO_REF:0000107 MGI:3701380 NCBI chr 4:119,872,066...119,877,694
Ensembl chr 4:119,872,045...119,878,627
JBrowse link
G Naca nascent polypeptide associated complex subunit alpha involved_in ISO (MGI:4867362|PMID:21071677) RGD PMID:21071677 MGI:4867362 NCBI chr 7:468,862...481,992
Ensembl chr 7:469,723...481,992
JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region involved_in ISO (MGI:3701380|PMID:17336907) RGD PMID:17336907 MGI:3701380 NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353
JBrowse link
G Sox9 SRY-box transcription factor 9 acts_upstream_of_or_within ISO MGI:2385468|MGI:2450311 (MGI:3709829|PMID:17350610) RGD PMID:17350610 MGI:3709829 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994
JBrowse link
positive regulation of cell proliferation involved in heart valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smad4 SMAD family member 4 involved_in IEA
ISO
GO_REF:0000107
(MGI:4946551|PMID:21330551)
Ensembl
RGD
PMID:21330551 GO_REF:0000107 MGI:4946551 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438
JBrowse link
positive regulation of cell proliferation involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in IEA
ISO
GO_REF:0000107
(MGI:3039210|PMID:15070745)
Ensembl
RGD
PMID:15070745 GO_REF:0000107 MGI:3039210 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
positive regulation of secondary heart field cardioblast proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eya1 EYA transcriptional coactivator and phosphatase 1 acts_upstream_of_or_within ISO MGI:102780 (MGI:5002778|PMID:21364285) RGD PMID:21364285 MGI:5002778 NCBI chr 5:4,863,501...5,101,483
Ensembl chr 5:4,955,543...5,101,483
JBrowse link
G Gng5 G protein subunit gamma 5 acts_upstream_of_or_within ISO (MGI:5604689|PMID:24599258) RGD PMID:24599258 MGI:5604689 NCBI chr 2:235,394,680...235,403,177
Ensembl chr 1:77,292,043...77,292,513
JBrowse link
G Six1 SIX homeobox 1 acts_upstream_of_or_within ISO MGI:109344 (MGI:5002778|PMID:21364285) RGD PMID:21364285 MGI:5002778 NCBI chr 6:91,746,739...91,751,975
Ensembl chr 6:91,746,739...91,751,975
JBrowse link
G Tbx1 T-box transcription factor 1 acts_upstream_of_or_within ISO (MGI:4943633|PMID:19745164) RGD PMID:19745164 MGI:4943633 NCBI chr11:82,409,275...82,419,058
Ensembl chr11:82,409,275...82,418,380
JBrowse link
G Tbx5 T-box transcription factor 5 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2387851 (MGI:5437816|PMID:22898775)
Ensembl
RGD
PMID:22898775 GO_REF:0000107 MGI:5437816 NCBI chr12:36,686,344...36,739,253
Ensembl chr12:36,688,014...36,734,885
JBrowse link
regulation of cardioblast proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Notch1 notch receptor 1 IMP RGD PMID:18824567 RGD:2325311 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
regulation of secondary heart field cardioblast proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctnnb1 catenin beta 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4438134|PMID:19620969)
GO_REF:0000107
RGD
Ensembl
PMID:19620969 GO_REF:0000107 MGI:4438134 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 involved_in IEA
ISO
GO_REF:0000107
(MGI:4413411|PMID:19008477)
Ensembl
RGD
PMID:19008477 GO_REF:0000107 MGI:4413411 NCBI chr16:32,917,826...32,919,880
Ensembl chr16:32,917,823...32,919,891
JBrowse link
G Hes1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:4354447|PMID:19609448)
Ensembl
RGD
PMID:19609448 GO_REF:0000107 MGI:4354447 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
JBrowse link
G Isl1 ISL LIM homeobox 1 acts_upstream_of_or_within ISO MGI:2447758 (MGI:4438134|PMID:19620969) RGD PMID:19620969 MGI:4438134 NCBI chr 2:48,079,412...48,090,704
Ensembl chr 2:48,080,522...48,095,584
JBrowse link
smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mks1 MKS transition zone complex subunit 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:4821832 (MGI:5811184|PMID:27340223)
Ensembl
RGD
PMID:27340223 GO_REF:0000107 MGI:5811184 NCBI chr10:72,655,921...72,667,007
Ensembl chr10:72,655,921...72,666,655
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20094
    cellular process 18691
      cell population proliferation 2293
        regulation of cell population proliferation 1931
          regulation of cell proliferation involved in heart morphogenesis 22
            negative regulation of cell proliferation involved in heart morphogenesis + 4
            positive regulation of cell proliferation involved in heart morphogenesis + 7
            regulation of cardioblast proliferation + 12
            regulation of cell proliferation involved in heart valve morphogenesis + 3
            regulation of cell proliferation involved in outflow tract morphogenesis + 3
Path 2
Term Annotations click to browse term
  biological_process 20094
    developmental process 7006
      anatomical structure development 6444
        multicellular organism development 5224
          system development 4484
            circulatory system development 1328
              heart development 719
                heart morphogenesis 287
                  cell proliferation involved in heart morphogenesis 24
                    regulation of cell proliferation involved in heart morphogenesis 22
                      negative regulation of cell proliferation involved in heart morphogenesis + 4
                      positive regulation of cell proliferation involved in heart morphogenesis + 7
                      regulation of cardioblast proliferation + 12
                      regulation of cell proliferation involved in heart valve morphogenesis + 3
                      regulation of cell proliferation involved in outflow tract morphogenesis + 3
paths to the root