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ONTOLOGY REPORT - ANNOTATIONS


Term:blood vessel endothelial cell proliferation involved in sprouting angiogenesis
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Accession:GO:0002043 term browser browse the term
Definition:The multiplication or reproduction of blood vessel endothelial cells, resulting in the expansion of a cell population contributing to sprouting angiogenesis.
Synonyms:related_synonym: blood vessel endothelial cell proliferation during sprouting angiogenesis


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blood vessel endothelial cell proliferation involved in sprouting angiogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in ISO (PMID:18787191) BHF-UCL PMID:18787191 NCBI chrNW_004955409:9,432,835...9,439,680
Ensembl chrNW_004955409:9,432,841...9,440,303
JBrowse link
G Epha2 EPH receptor A2 acts_upstream_of_or_within ISO (PMID:19443703) MGI PMID:19443703 NCBI chrNW_004955527:2,120,447...2,151,932
Ensembl chrNW_004955527:2,120,266...2,152,781
JBrowse link
G Itgb1bp1 integrin subunit beta 1 binding protein 1 involved_in ISO (PMID:20616313) UniProt PMID:20616313 NCBI chrNW_004955487:5,134,135...5,146,449
Ensembl chrNW_004955487:5,134,135...5,146,449
JBrowse link
G Sema5a semaphorin 5A involved_in ISO (PMID:19850054) UniProt PMID:19850054 NCBI chrNW_004955504:6,343,747...6,691,945
Ensembl chrNW_004955504:6,350,866...6,762,104
JBrowse link
negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dll4 delta like canonical Notch ligand 4 involved_in ISO (PMID:23388056) UniProt PMID:23388056 NCBI chrNW_004955416:7,807,049...7,816,346
Ensembl chrNW_004955416:7,807,049...7,817,420
JBrowse link
G Il12a interleukin 12A acts_upstream_of ISO (PMID:30106099) ARUK-UCL PMID:30106099 NCBI chrNW_004955448:10,611,131...10,617,911 JBrowse link
G Il12b interleukin 12B acts_upstream_of ISO (PMID:30106099) ARUK-UCL PMID:30106099 NCBI chrNW_004955408:13,302,506...13,316,300
Ensembl chrNW_004955408:13,304,219...13,312,620
JBrowse link
G Mmrn2 multimerin 2 involved_in ISO (PMID:25745997) ComplexPortal PMID:25745997 NCBI chrNW_004955510:5,943,126...5,957,679
Ensembl chrNW_004955510:5,945,043...5,958,352
JBrowse link
G Ngfr nerve growth factor receptor involved_in ISO (PMID:26268439) BHF-UCL PMID:26268439 NCBI chrNW_004955451:12,030,303...12,047,305
Ensembl chrNW_004955451:12,030,252...12,047,305
JBrowse link
G Pdcd10 programmed cell death 10 involved_in ISO (PMID:23388056) UniProt PMID:23388056 NCBI chrNW_004955448:16,866,577...16,887,215
Ensembl chrNW_004955448:16,864,031...16,887,626
JBrowse link
G Thbs1 thrombospondin 1 involved_in ISO (PMID:25660232) BHF-UCL PMID:25660232 NCBI chrNW_004955416:6,490,034...6,506,419
Ensembl chrNW_004955416:6,489,451...6,506,419
JBrowse link
positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr1 angiotensin II receptor type 1 involved_in ISO (PMID:25850724) BHF-UCL PMID:25850724 NCBI chrNW_004955474:8,733,942...8,781,305
Ensembl chrNW_004955474:8,733,942...8,781,255
JBrowse link
G Apela apelin receptor early endogenous ligand involved_in ISO (PMID:28890073) UniProt PMID:28890073 NCBI chrNW_004955403:40,257,467...40,266,275 JBrowse link
G Aplnr apelin receptor involved_in ISO (PMID:28890073) UniProt PMID:28890073 NCBI chrNW_004955511:2,321,445...2,324,417
Ensembl chrNW_004955511:2,322,920...2,324,068
JBrowse link
G Fgfbp1 fibroblast growth factor binding protein 1 involved_in ISO (PMID:27121396) BHF-UCL PMID:27121396 NCBI chrNW_004955480:8,088,670...8,091,882
Ensembl chrNW_004955480:8,088,670...8,091,882
JBrowse link
G Gata2 GATA binding protein 2 involved_in ISO (PMID:27780851) BHF-UCL PMID:27780851 NCBI chrNW_004955429:15,326,551...15,334,774
Ensembl chrNW_004955429:15,327,113...15,336,460
JBrowse link
G Hmox1 heme oxygenase 1 involved_in ISO (PMID:24844779) BHF-UCL PMID:24844779 NCBI chrNW_004955405:43,124,447...43,128,873
Ensembl chrNW_004955405:43,124,510...43,130,979
JBrowse link
G Jcad junctional cadherin 5 associated involved_in ISO (PMID:28705794) BHF-UCL PMID:28705794 NCBI chrNW_004955429:21,954,274...22,038,953
Ensembl chrNW_004955429:21,954,149...22,035,754
JBrowse link
G Ppp1r16b protein phosphatase 1 regulatory subunit 16B involved_in ISO (PMID:25007873) GO_Central PMID:25007873 NCBI chrNW_004955445:17,864,103...17,961,295
Ensembl chrNW_004955445:17,863,556...17,962,052
JBrowse link
G Vegfa vascular endothelial growth factor A involved_in
acts_upstream_of
ISO (PMID:24844779)
(PMID:30106099)
BHF-UCL
ARUK-UCL
PMID:24844779 PMID:30106099 NCBI chrNW_004955437:9,527,445...9,541,908 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12572
    cellular process 12010
      cell population proliferation 1959
        epithelial cell proliferation 484
          endothelial cell proliferation 165
            blood vessel endothelial cell proliferation involved in sprouting angiogenesis 20
              negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis 7
              positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis 9
              regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis + 16
Path 2
Term Annotations click to browse term
  biological_process 12572
    developmental process 5945
      anatomical structure development 5623
        multicellular organism development 4600
          system development 4003
            circulatory system development 1164
              vasculature development 735
                blood vessel development 700
                  blood vessel morphogenesis 593
                    angiogenesis 489
                      sprouting angiogenesis 128
                        blood vessel endothelial cell proliferation involved in sprouting angiogenesis 20
                          negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis 7
                          positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis 9
                          regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis + 16
paths to the root