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ONTOLOGY REPORT - ANNOTATIONS

Term:radial spoke
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Accession:GO:0001534 term browser browse the term
Definition:Protein complex that links the outer microtubule doublet of a 9+2 type ciliary or flagellar axoneme with the sheath that surrounds the central pair of microtubules. Composed of a stalk that attaches to each doublet microtubule and a globular structure (spoke head) that projects toward the central pair of microtubules.
Comment:Radial spokes are involved in some types of beating motions of the cilium. The radial spoke is usually a T-shaped structure comprised of a short base that attaches to the A-microtubule of an axonemal outer microtubule doublet (MTD) of a cilium, an elongated stalk, a neck complex, and an orthogonal head structure that extends perpendicularly towards the inner sheath and the central pair (CP) microtubules. Groups of radial spokes (RSs) repeat along the MTD with regular spacing. In most organisms, each group of radial spokes is comprised of a triplet of spokes: RS1, RS2, and RS3. In some organisms (e.g. Chlamydomonas and Sarcophaga bullata), each group contains a doublet of radial spokes: RS1 and RS2, while RS3 is represented only as a stump (referred to as RS3S) attached to the A-microtubule but lacking the rest of the stalk structure and entirely lacking the head structure. {xref="PMID:9450971", xref="GOC:krc", xref="PMID:34871179", xref="PMID:25694453"}
Synonyms:xref: Wikipedia:Radial_spoke


show annotations for term's descendants           Sort by:
radial spoke term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cfap119 cilia and flagella associated protein 119 part_of IDA (PMID:37601242) MGI PMID:37601242 NCBI chr 7:127,182,527...127,187,819
Ensembl chr 7:127,181,555...127,187,767 		JBrowse link
G Cfap206 cilia and flagella associated protein 206 part_of ISS UniProt GO_REF:0000024 NCBI chr 4:34,688,574...34,730,263
Ensembl chr 4:34,688,559...34,730,206 		JBrowse link
G Cfap61 cilia and flagella associated protein 61 part_of ISA (PMID:34792097) MGI PMID:34792097 NCBI chr 2:145,776,677...146,056,955
Ensembl chr 2:145,776,704...146,056,959 		JBrowse link
G Dnajb13 DnaJ heat shock protein family (Hsp40) member B13 part_of IDA (PMID:36417862) UniProt PMID:36417862 NCBI chr 7:100,152,218...100,182,834
Ensembl chr 7:100,150,923...100,164,167 		JBrowse link
G Dydc1 DPY30 domain containing 1 part_of IDA (PMID:36417862) UniProt PMID:36417862 NCBI chr14:40,794,834...40,814,154
Ensembl chr14:40,794,868...40,814,154 		JBrowse link
G Iqub IQ motif and ubiquitin domain containing part_of IDA (PMID:36417862) UniProt PMID:36417862 NCBI chr 6:24,444,864...24,515,066
Ensembl chr 6:24,444,864...24,515,066 		JBrowse link
G Nme5 NME/NM23 family member 5 part_of IDA (PMID:36417862) UniProt PMID:36417862 NCBI chr18:34,695,687...34,712,168
Ensembl chr18:34,695,687...34,712,168 		JBrowse link
G Ropn1l ropporin 1-like part_of IDA (PMID:36417862) UniProt PMID:36417862 NCBI chr15:31,441,356...31,453,835
Ensembl chr15:31,441,357...31,453,883 		JBrowse link
G Rsph1 radial spoke head 1 homolog (Chlamydomonas) part_of IDA (PMID:36417862) UniProt PMID:36417862 NCBI chr17:31,473,993...31,496,270
Ensembl chr17:31,473,993...31,496,357 		JBrowse link
G Rsph14 radial spoke head homolog 14 (Chlamydomonas) part_of IDA (PMID:36417862) UniProt PMID:36417862 NCBI chr10:74,793,309...74,868,475
Ensembl chr10:74,793,309...74,868,418 		JBrowse link
G Rsph4a radial spoke head 4 homolog A (Chlamydomonas) part_of ISS UniProt GO_REF:0000024 NCBI chr10:33,781,107...33,792,017
Ensembl chr10:33,781,107...33,792,017 		JBrowse link
G Rsph6a radial spoke head 6 homolog A (Chlamydomonas) part_of IDA (PMID:36417862) UniProt PMID:36417862 NCBI chr 7:18,788,603...18,808,384
Ensembl chr 7:18,788,615...18,808,372 		JBrowse link
G Rsph9 radial spoke head 9 homolog (Chlamydomonas) part_of IDA (PMID:36417862) UniProt PMID:36417862 NCBI chr17:46,432,964...46,455,171
Ensembl chr17:46,432,961...46,455,142 		JBrowse link
radial spoke head term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rsph1 radial spoke head 1 homolog (Chlamydomonas) part_of IDA (PMID:34871179) UniProt PMID:34871179 NCBI chr17:31,473,993...31,496,270
Ensembl chr17:31,473,993...31,496,357 		JBrowse link
G Rsph3a radial spoke 3A homolog (Chlamydomonas) part_of ISS UniProt GO_REF:0000024 NCBI chr17:8,164,446...8,198,388
Ensembl chr17:8,164,446...8,198,656 		JBrowse link
G Rsph3b radial spoke 3B homolog (Chlamydomonas) part_of IDA (PMID:34871179) UniProt PMID:34871179 NCBI chr17:7,172,115...7,215,755
Ensembl chr17:7,171,812...7,216,081 		JBrowse link
G Rsph4a radial spoke head 4 homolog A (Chlamydomonas) part_of IMP
IDA		 (PMID:26506310)
(PMID:34871179)		 MGI
UniProt		 PMID:26506310 PMID:34871179 NCBI chr10:33,781,107...33,792,017
Ensembl chr10:33,781,107...33,792,017 		JBrowse link
G Rsph6a radial spoke head 6 homolog A (Chlamydomonas) part_of ISA
IDA
IPI		 (PMID:11237735)
(PMID:34871179)
(PMID:30185526)		 MGI
UniProt		 PMID:11237735 PMID:30185526 PMID:34871179 NCBI chr 7:18,788,603...18,808,384
Ensembl chr 7:18,788,615...18,808,372 		JBrowse link
G Rsph9 radial spoke head 9 homolog (Chlamydomonas) part_of IDA (PMID:34871179) UniProt PMID:34871179 NCBI chr17:46,432,964...46,455,171
Ensembl chr17:46,432,961...46,455,142 		JBrowse link
radial spoke head 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rsph1 radial spoke head 1 homolog (Chlamydomonas) part_of IDA (PMID:34871179) MGI PMID:34871179 NCBI chr17:31,473,993...31,496,270
Ensembl chr17:31,473,993...31,496,357 		JBrowse link
G Rsph3b radial spoke 3B homolog (Chlamydomonas) part_of IDA (PMID:34871179) MGI PMID:34871179 NCBI chr17:7,172,115...7,215,755
Ensembl chr17:7,171,812...7,216,081 		JBrowse link
G Rsph4a radial spoke head 4 homolog A (Chlamydomonas) part_of IDA (PMID:32203505), (PMID:34871179) MGI PMID:32203505 PMID:34871179 NCBI chr10:33,781,107...33,792,017
Ensembl chr10:33,781,107...33,792,017 		JBrowse link
G Rsph9 radial spoke head 9 homolog (Chlamydomonas) part_of IDA (PMID:34871179) MGI PMID:34871179 NCBI chr17:46,432,964...46,455,171
Ensembl chr17:46,432,961...46,455,142 		JBrowse link
radial spoke head 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rsph4a radial spoke head 4 homolog A (Chlamydomonas) part_of IDA (PMID:32203505) MGI PMID:32203505 NCBI chr10:33,781,107...33,792,017
Ensembl chr10:33,781,107...33,792,017 		JBrowse link
radial spoke head 3 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rsph1 radial spoke head 1 homolog (Chlamydomonas) part_of IDA (PMID:34871179) MGI PMID:34871179 NCBI chr17:31,473,993...31,496,270
Ensembl chr17:31,473,993...31,496,357 		JBrowse link
G Rsph3b radial spoke 3B homolog (Chlamydomonas) part_of IDA (PMID:34871179) MGI PMID:34871179 NCBI chr17:7,172,115...7,215,755
Ensembl chr17:7,171,812...7,216,081 		JBrowse link
G Rsph4a radial spoke head 4 homolog A (Chlamydomonas) part_of IDA (PMID:32203505), (PMID:34871179) MGI PMID:32203505 PMID:34871179 NCBI chr10:33,781,107...33,792,017
Ensembl chr10:33,781,107...33,792,017 		JBrowse link
G Rsph9 radial spoke head 9 homolog (Chlamydomonas) part_of IDA (PMID:34871179) MGI PMID:34871179 NCBI chr17:46,432,964...46,455,171
Ensembl chr17:46,432,961...46,455,142 		JBrowse link
radial spoke stalk term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cfap61 cilia and flagella associated protein 61 part_of IPI
ISS		 (PMID:34792097) MGI
UniProt		 PMID:34792097 GO_REF:0000024 NCBI chr 2:145,776,677...146,056,955
Ensembl chr 2:145,776,704...146,056,959 		JBrowse link
G Cfap91 cilia and flagella associated protein 91 part_of ISS UniProt GO_REF:0000024 NCBI chr16:38,118,116...38,162,222
Ensembl chr16:38,118,116...38,162,505 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 28568
    protein-containing complex 6115
      radial spoke 16
        radial spoke 1 + 4
        radial spoke 2 + 1
        radial spoke 3 + 4
        radial spoke base + 0
        radial spoke head + 6
        radial spoke neck 0
        radial spoke stalk 2
Path 2
Term Annotations click to browse term
  cellular_component 28568
    cellular anatomical structure 19603
      intracellular anatomical structure 14908
        cytoplasm 12090
          cytoplasmic region 353
            plasma membrane bounded cell projection cytoplasm 311
              ciliary plasm 211
                axoneme 210
                  radial spoke 16
                    radial spoke 1 + 4
                    radial spoke 2 + 1
                    radial spoke 3 + 4
                    radial spoke base + 0
                    radial spoke head + 6
                    radial spoke neck 0
                    radial spoke stalk 2
paths to the root