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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Hand-Foot Syndrome
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Accession:DOID:9005708 term browser browse the term
Definition:Chemotherapy-induced dermal side effects that are associated with the use of various CYTOSTATIC AGENTS. Symptoms range from mild ERYTHEMA and/or PARESTHESIA to severe ulcerative dermatitis with debilitating pain involving typically palmoplantar and intertriginous areas. These cutaneous manifestations are sometimes accompanied by nail anomalies.
Synonyms:exact_synonym: Chemotherapy Induced Acral Erythema;   Chemotherapy Induced Palmoplantar Erythrodysesthesia;   Chemotherapy-Induced Acral Erythemas;   Chemotherapy-Induced Palmoplantar Erythrodysesthesias;   Hand-Foot Syndromes
 primary_id: MESH:D060831;   RDO:0010051
 xref: EFO:1001893


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Hand-Foot Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KDR kinase insert domain receptor treatment ISO DNA:polymorphism:cds:p.H472Q(human) RGD PMID:20630084 RGD:8552374 NCBI chr 8:41,809,116...41,856,379
Ensembl chr 8:41,809,122...41,856,336 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17412
    syndrome 9899
      Hand-Foot Syndrome 1
Path 2
Term Annotations click to browse term
  disease 17412
    Pathological Conditions, Signs and Symptoms 11803
      Signs and Symptoms 9742
        Neurologic Manifestations 9422
          sensory system disease 6515
            skin disease 3710
              dermatitis 454
                Drug Eruptions 70
                  Hand-Foot Syndrome 1
paths to the root