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RGD uses the Human Disease Ontology (DO, for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:multiple chemical sensitivity
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Accession:DOID:4661 term browser browse the term
Definition:An acquired disorder characterized by recurrent symptoms, referable to multiple organ systems, occurring in response to demonstrable exposure to many chemically unrelated compounds at doses below those established in the general population to cause harmful effects. (Cullen MR. The worker with multiple chemical sensitivities: an overview. Occup Med 1987;2(4):655-61)
Synonyms:exact_synonym: 20th century disease;   Idiopathic Environmental Intolerances;   Multiple Chemical Sensitivities;   chemical AIDS;   idiopathic environmental illness;   idiopathic environmental intolerance;   multiple chemical sensitivity syndrome;   total allergy syndrome
 primary_id: MESH:D018777
 alt_id: RDO:0007229
For additional species annotation, visit the Alliance of Genome Resources.

show annotations for term's descendants           Sort by:
multiple chemical sensitivity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 susceptibility ISO DNA:polymorphism: :CYP2C19*2(human) RGD PMID:23936614 RGD:124713563 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
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G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23967348 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17435
    syndrome 8262
      multiple chemical sensitivity 2
Path 2
Term Annotations click to browse term
  disease 17435
    disease of anatomical entity 16766
      Immune & Inflammatory Diseases 4049
        immune system disease 3407
          allergic disease 602
            Environmental Illness 3
              multiple chemical sensitivity 2
paths to the root