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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:multiple chemical sensitivity
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Accession:DOID:4661 term browser browse the term
Definition:A syndrome that is an adverse physical reaction to low levels of many common chemicals. (DO)
Synonyms:exact_synonym: 20th century disease;   chemical AIDS;   idiopathic environmental illness;   idiopathic environmental intolerance;   idiopathic environmental intolerances;   multiple chemical sensitivities;   multiple chemical sensitivity syndrome;   total allergy syndrome
 primary_id: MESH:D018777
 xref: EFO:0007382
For additional species annotation, visit the Alliance of Genome Resources.


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multiple chemical sensitivity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 susceptibility ISO DNA:polymorphism: :CYP2C19*2(human) RGD PMID:23936614 RGD:124713563 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23967348 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sord sorbitol dehydrogenase ISO ClinVar Annotator: match by term: Idiopathic environmental intolerance ClinVar PMID:8622605 PMID:25741868 PMID:32367058 PMID:32457452 PMID:33201363 More... NCBI chr 3:109,184,697...109,216,133
Ensembl chr 3:109,184,676...109,216,133 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 21128
    syndrome 10833
      multiple chemical sensitivity 3
Path 2
Term Annotations click to browse term
  disease 21128
    disease of anatomical entity 18211
      Immune & Inflammatory Diseases 5566
        immune system disease 4773
          allergic disease 611
            Environmental Illness 5
              multiple chemical sensitivity 3
paths to the root