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RGD uses the Human Disease Ontology (DO, for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:heart disease
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Accession:DOID:114 term browser browse the term
Definition:A cardiovascular system disease that involves the heart. (DO)
Synonyms:exact_synonym: cardiac disease;   cardiac diseases;   heart diseases
 narrow_synonym: Abnormal cardiac atrium morphology
 primary_id: MESH:D006331
 xref: EFO:0003777;   HP:0005120;   ICD10CM:I51.9;   ICD9CM:429.9;   NCI:C3079
For additional species annotation, visit the Alliance of Genome Resources.

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    Term Annotations click to browse term
      disease 19072
        disease of anatomical entity 18365
          cardiovascular system disease 5562
            heart disease 3443
              Acute Heart Injury 2
              Carcinoid Heart Disease 0
              Cardiac Arrhythmias + 762
              Cardiac Fibrosis + 64
              Cardiac Output, Low 3
              Cardiomegaly + 943
              GM1 gangliosidosis type 1 5
              Heart Neoplasms + 3
              Heart Rupture + 2
              High Cardiac Output 1
              Myocardial Ischemia + 948
              Pneumopericardium 0
              Postpericardiotomy Syndrome 0
              Ventricular Dysfunction + 73
              Ventricular Outflow Obstruction + 446
              agenesis of corpus callosum, cardiac, ocular, and genital syndrome 1
              autoimmune cardiomyopathy 0
              cardiac tuberculosis + 0
              cardiomyopathy + 1407
              chronic atrial and intestinal dysrhythmia 1
              congenital heart disease + 1385
              congestive heart failure + 554
              cystic echinococcosis 5
              cysticercosis + 0
              endocarditis + 1
              endocardium disease + 107
              heart aneurysm + 5
              heart conduction disease + 465
              heart lipoma + 0
              heart valve disease + 539
              heterophyiasis 0
              hypertensive heart disease 2
              immunoglobulin light chain amyloidosis 3
              lethal congenital glycogen storage disease of heart 25
              myocardial stunning 4
              pericardium disease + 6
              toxocariasis + 3
              transthyretin amyloidosis 8
              wild-type amyloidosis 0
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