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Ontology Browser

Term:
immunoglobulin light chain amyloidosis (DOID:0080933)
Annotations: Rat: (3) Mouse: (4) Human: (3) Chinchilla: (1) Bonobo: (3) Dog: (3) Squirrel: (2) Pig: (2)
Parent Terms Term With Siblings Child Terms
amyloidosis +     
heart disease +     
kidney disease +     
liver disease +     
3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 Deficiency  
3-Hydroxyacyl-CoA Dehydrogenase Deficiency  
3-methylglutaconic aciduria +   
46,XX Sex Reversal with Dysgenesis of Kidneys, Adrenals, and Lungs  
5-Nucleotidase Syndrome 
6-Phosphogluconolactonase Deficiency 
aceruloplasminemia  
Acetylcarnitine Deficiency 
Acholinesterasemia 
Acid Phosphatase Deficiency  
Acute Heart Injury  
Acute Reversible Leukoencephalopathy with Increased Urinary Alpha-ketoglutarate  
agenesis of corpus callosum, cardiac, ocular, and genital syndrome  
AIDS-Associated Nephropathy  
Alcoholic Liver Diseases +   
alpha 1-antitrypsin deficiency  
Alpha-Fetoprotein Deficiency  
Alsing Syndrome 
alveolar echinococcosis  
amino acid metabolic disorder +   
Amino Acid Transport Disorders, Inborn +   
Amyloid Neuropathies +   
Angiotensin I-Converting Enzyme, Benign Serum Increase  
anuria +   
apolipoprotein A-IV associated amyloidosis 
Arene Oxide Detoxification Defect 
Arnold Stickler Bourne Syndrome 
aromatase excess syndrome  
Aryl Hydrocarbon Hydroxylase Inducibility 
atheroembolism of kidney 
autoimmune cardiomyopathy 
Autoimmune Interstitial Lung, Joint, and Kidney Disease  
Bifid Nose with or without Anorectal and Renal Anomalies  
bilirubin metabolic disorder +   
Blue Diaper Syndrome 
Budd-Chiari syndrome +   
Butyrylcholinesterase Deficiency  
Butyrylcholinesterase Deficiency, Fluoride-Resistant, Japanese Type  
CAKUT1  
capillariasis 
carbohydrate metabolic disorder +   
carbohydrate metabolism disease +   
CARBONIC ANHYDRASE VA DEFICIENCY, HYPERAMMONEMIA DUE TO  
Carcinoid Heart Disease 
cardiac arrest +   
Cardiac Arrhythmias +   
Cardiac Fibrosis  
Cardiac Output, High  
Cardiac Output, Low  
cardiac tuberculosis +  
Cardiomegaly +   
cardiomyopathy +   
Carnitine Acetyltransferase Deficiency  
Carnitine Palmitoyltransferase II Deficiency, Infantile  
carotenemia +   
cerebral amyloid angiopathy +   
CHITOTRIOSIDASE DEFICIENCY  
Chromate Resistance 
chronic atrial and intestinal dysrhythmia  
clonorchiasis  
COACH syndrome +   
Combined Congenital Deficiency of Intrinsic Factor and R Binder 
Combined Defect of Growth Factors 
Combined Exocrine Pancreatic Insufficiency 
Combined Immunodeficiency and Megaloblastic Anemia with or without Hyperhomocysteinemia  
Complement Factor H Deficiency  
congenital heart disease +   
congenital leptin deficiency  
congenital secretory chloride diarrhea 1  
congenital secretory sodium diarrhea 3  
congestive heart failure +   
Copper Deficiency, Familial Benign 
Coumarin Sensitivity  
Cyanosis and Hepatic Disease 
cystic echinococcosis  
cystic kidney disease +   
cysticercosis +  
cytochrome-c oxidase deficiency disease +   
Deafness Hyperuricemia Neurologic Ataxia 
Defect in Hyaluronan Metabolism 
Defect in Hydroxylation of Diphenylhydantoin 
Deficient N-Hydroxylation of Amobarbital 
Deoxyribose-5-Phosphate Aldolase Deficiency 
diabetes insipidus +   
Diabetic Nephropathies  
dialysis-related amyloidosis 
Dimauro Disease  
dioctophymiasis 
dopamine beta-hydroxylase deficiency  
DYSOSTOSIS MULTIPLEX, AIN-NAZ TYPE  
Efavirenz, Poor Metabolism of  
endocarditis +   
endocardium disease +   
enterokinase deficiency  
Ethanolaminosis 
Familial Amyloidosis +   
familial erythrocytosis 8  
familial hypocalciuric hypercalcemia +   
Familial Hypokalemia +   
familial juvenile hyperuricemic nephropathy +   
fatty liver disease +   
Focal Nodular Hyperplasia 
FUCOSYLTRANSFERASE 6 DEFICIENCY  
Glomerular Diseases +   
Glucocorticoid Receptor Deficiency  
Glucose-Stimulated Secretory Diarrhea, with Common Variable Immunodeficiency 
Glycogen Storage Disease 0, Liver  
glycogen storage disease IX +   
glycogen storage disease VI  
Glycoprotein Storage Disease  
Glyoxalase II Deficiency  
GM1 gangliosidosis type 1  
Goodpasture syndrome +   
Gordon Holmes syndrome  
granulomatosis with polyangiitis +   
Greenberg dysplasia  
GROWTH RETARDATION, INTELLECTUAL DEVELOPMENTAL DISORDER, HYPOTONIA, AND HEPATOPATHY  
GSD IV, Nonprogressive Hepatic 
Hantavirus hemorrhagic fever with renal syndrome +   
heart aneurysm +   
heart conduction disease +   
heart lipoma +  
Heart Neoplasms +  
Heart Rupture +   
heart valve disease +   
Hepatic Insufficiency +   
Hepatic Porphyrias +   
hepatic tuberculosis 
hepatic vascular disease +   
hepatitis +   
Hepatomegaly +   
hepatopulmonary syndrome  
hepatorenal syndrome  
Hereditary Hyperbilirubinemia +   
Herrmann Syndrome 
heterophyiasis 
Hydranencephaly with Renal Aplasia-Dysplasia  
hydronephrosis +   
Hypercalcemia, Infantile, 1  
Hyperoxaluria +   
hyperphosphatemic familial tumoral calcinosis +   
hyperprolactinemia +   
hypertensive heart disease  
hyperuricemia +   
Hypoadiponectinemia  
hypoinsulinemic hypoglycemia with hemihypertrophy  
hypophosphatemic nephrolithiasis/osteoporosis +   
Ichthyosis, Mental Retardation, Dwarfism, and Renal Impairment 
immunodeficiency 43  
immunoglobulin heavy chain amyloidosis 
immunoglobulin heavy-and-light chain 
immunoglobulin light chain amyloidosis  
An amyloidosis that is characterized by misfolded and aggregated amyloidogenic immunoglobulin light chains produced by marrow clonal plasma cells. (DO)
Infundibulopelvic Dysgenesis 
Inosine Triphosphatase Deficiency  
INTERSTITIAL LUNG AND LIVER DISEASE  
intrahepatic cholestasis +   
isolated elevated serum creatine phosphokinase levels  
isolated hyperchlorhidrosis  
Jejunal Atresia with Renal Adysplasia 
Joubert syndrome 5  
Joubert syndrome 6  
Joubert syndrome 9  
Kallikrein, Decreased Urinary Activity of  
kidney cortex disease +   
kidney failure +   
kidney hypertrophy 
Kidney Neoplasms +   
kidney papillary necrosis 
Lachiewicz Sibley Syndrome 
Lactate Dehydrogenase B Deficiency  
Lactic Aciduria due to D-Lactic Acid  
Leptin Receptor Deficiency  
lethal congenital glycogen storage disease of heart  
Leukotriene C4 Synthase Deficiency  
lipid metabolism disorder +   
Lipoprotein Glomerulopathy  
Liver Abscess +   
liver carcinoma in situ 
liver cirrhosis +   
Liver Fibrocystic Disease and Polydactyly 
liver inflammatory pseudotumor 
Liver Injury +   
Liver Neoplasms +   
Lymphedema-Distichiasis Syndrome with Renal Disease and Diabetes Mellitus  
lysosomal storage disease +   
Malonic Aciduria  
Mannose 6-Phosphate Receptor Recognition Defect, Lebanese Type 
Mannose-Binding Protein Deficiency  
maturity-onset diabetes of the young +   
Medium Chain 3-Ketoacyl-CoA Thiolase Deficiency 
metabolic acidosis +   
Metabolic Brain Diseases, Inborn +   
metal metabolism disorder +   
Methemoglobin Reductase Deficiency 
Methylmalonyl-Coenzyme A Mutase Deficiency 
mineral metabolism disease +   
mitochondrial DNA depletion syndrome 6  
mitochondrial metabolism disease +   
MITOCHONDRIAL SHORT-CHAIN ENOYL-COA HYDRATASE 1 DEFICIENCY  
Monocarboxylate Transporter 1 Deficiency  
Monocyte Esterase Deficiency  
Muckle-Wells syndrome  
Myeloperoxidase Deficiency  
Myocardial Ischemia +   
myocardial stunning  
N Acetyltransferase Deficiency +   
neonatal diabetes mellitus with congenital hypothyroidism  
nephritis +   
nephrocalcinosis +   
nephrogenic diabetes insipidus +   
nephrolithiasis +   
Nephropathy with Pretibial Epidermolysis Bullosa and Deafness  
nephrosclerosis +   
NEURODEVELOPMENTAL DISORDER WITH MICROCEPHALY, CATARACTS, AND RENAL ABNORMALITIES  
Nonfunctional L-Gulonolactone Oxidase 
Nonspherocytic Hemolytic Anemia due to Glucose Phosphate Isomerase Deficiency  
Nonspherocytic Hemolytic Anemia, due to Hexokinase Deficiency  
nutrition disease +   
obstructive nephropathy  
opisthorchiasis  
orthostatic proteinuria 
overhydrated hereditary stomatocytosis  
paragonimiasis 
Parasitic Liver Diseases +   
peliosis hepatis  
pericardium disease +   
perinephritis 
permanent neonatal diabetes mellitus +   
peroxisomal disease +   
Phenacetin O-Deethylase, Deficiency of  
Phenol Sulfotransferase Deficiency 
Phosphoenolpyruvate Carboxykinase Deficiency +   
phosphoglycerate kinase 1 deficiency  
Phosphohydroxylysinuria  
plasma protein metabolism disease +   
Pneumopericardium 
polycystic echinococcosis 
polycystic liver disease +   
Poor Drug Metabolism, CYP2C19-Related  
Poor Drug Metabolism, CYP2D6-Related  
Poor Metabolism of Proguanil  
porphyria +   
Postpericardiotomy Syndrome 
Premature Atherosclerosis with Deafness, Nephropathy, Diabetes Mellitus, Photomyoclonus, and Degenerative Neurologic Disease 
progeria +   
proteinuria +   
Pseudo-TORCH Syndrome 2  
purine-pyrimidine metabolic disorder +   
pyelitis +   
pyrimidine metabolic disorder +   
Radiation Nephropathy  
Radio Renal Syndrome 
Recurrent Infections, with Encephalopathy, Hepatic Dysfunction, and Cardiovascular Malformations  
renal agenesis +   
renal artery disease +   
renal artery obstruction +   
Renal Dysplasia - Limb Defects Syndrome 
renal fibrosis +   
renal hypertension +   
renal hypoplasia +   
renal infectious disease 
Renal Ischemia  
Renal Nutcracker Syndrome 
renal osteodystrophy  
renal tuberculosis  
Renal Tubular Dysgenesis  
renal tubular transport disease +   
Renal Tubulopathy, Diabetes Mellitus, and Cerebellar Ataxia due to Duplication of Mitochondrial DNA 
renal-hepatic-pancreatic dysplasia +   
Reperfusion Injury +   
Retinohepatoendocrinologic Syndrome 
Retinol-Binding Protein Deficiency 
rheumatic heart disease +   
secondary hyperparathyroidism of renal origin 
SEDOHEPTULOKINASE DEFICIENCY  
Selig Benacerraf Greene Syndrome 
sepiapterin reductase deficiency  
serum amyloid A amyloidosis 
Siegler Brewer Carey Syndrome 
Spastic Paraplegia, Sensorineural Deafness, Mental Retardation, and Progressive Nephropathy 
Squalene Synthase Deficiency  
steroid inherited metabolic disorder +   
Stomatocytosis II  
stricture or kinking of ureter 
Succinic Acidemia 
SULFIDE:QUINONE OXIDOREDUCTASE DEFICIENCY  
Thiamine Metabolism Dysfunction Syndrome 4 (Bilateral Striatal Degeneration and Progressive Polyneuropathy Type)  
Thiamine Metabolism Dysfunction Syndrome 5 (Episodic Encephalopathy Type)  
thiopurine S-methyltransferase deficiency +   
Thrombocytopenia with Elevated Serum Iga and Renal Disease 
Thyrocerebral-Retinal Syndrome 
Thyrotropin-Releasing Hormone Deficiency  
toxocariasis +   
Transcobalamin I Deficiency  
transthyretin amyloidosis  
Trichohepatoneurodevelopmental Syndrome  
trimethylaminuria  
Trypsinogen Deficiency  
type 1 diabetes mellitus 2  
tyrosinemia type II  
uremia +   
Uridine-Cytidineuria  
variant ABeta2M amyloidosis 
Ventricular Dysfunction +   
Ventricular Outflow Obstruction +   
visceral leishmaniasis  
vitamin metabolic disorder +   
warfarin resistance  
warfarin sensitivity +   
Webb-Dattani Syndrome  
Weinstein Kliman Scully Syndrome 
Wiedemann Oldigs Oppermann Syndrome 
wild-type amyloidosis 
Wilson disease +   
Yorifuji Okuno Syndrome 
Zellweger syndrome +   

Synonyms
Exact Synonyms: AL Amyloidosis ;   Light chain amyloidosis ;   Primary Amyloidosis ;   Primary Systemic Amyloidosis ;   primary amyloid
Primary IDs: MESH:D000075363
Alternate IDs: DOID:9005869
Xrefs: ICD10CM:E85.81
Definition Sources: https://pubmed.ncbi.nlm.nih.gov/26771835/ "DO" "DO", https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841939/ "DO" "DO"

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