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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Myocardial Ischemia
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Accession:DOID:9007102 term browser browse the term
Definition:A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
Synonyms:exact_synonym: Ischemic Heart Disease;   Ischemic Heart Diseases;   Myocardial Ischemias
 related_synonym: Ischemic heart disease, susceptibility to;   SUPEROXIDE DISMUTASE, ELEVATED EXTRACELLULAR
 primary_id: MESH:D017202;   RDO:0004847
For additional species annotation, visit the Alliance of Genome Resources.


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Myocardial Ischemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acot2 acyl-CoA thioesterase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 6:107,460,596...107,468,324
Ensembl chr 6:107,460,668...107,467,487
JBrowse link
G Actb actin, beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr12:13,715,843...13,718,813
Ensembl chr12:13,715,843...13,718,841
JBrowse link
G Acvr1b activin A receptor type 1B IEP RGD PMID:14993131 RGD:1580888 NCBI chr 7:142,817,174...142,858,365
Ensembl chr 7:142,817,157...142,860,572
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO CTD Direct Evidence: therapeutic CTD PMID:16155579 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Adm adrenomedullin ISO protein:increased expression:plasma RGD PMID:15350700 RGD:1625302 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259
JBrowse link
G Adm2 adrenomedullin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16987513 NCBI chr 7:130,296,895...130,298,641
Ensembl chr 7:130,296,897...130,298,644
JBrowse link
G Adrb1 adrenoceptor beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9554809 NCBI chr 1:277,537,585...277,538,985
Ensembl chr 1:277,537,585...277,538,985
JBrowse link
G Adrb2 adrenoceptor beta 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9554809 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834
JBrowse link
G Ager advanced glycosylation end product-specific receptor ISO associated with Diabetes Mellitus, Type 2;DNA:SNP:promoter:-374T>A (human) RGD PMID:15896660 RGD:8695969 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Agt angiotensinogen ISO CTD Direct Evidence: marker/mechanism CTD PMID:16775501 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Ak1 adenylate kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 3:11,652,143...11,659,135 JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B IDA protein:increased activity:heart RGD PMID:16567803 RGD:1626092 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member IDA RGD PMID:18787169 RGD:7241592 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 6:108,146,552...108,167,185
Ensembl chr 6:108,146,582...108,167,185
JBrowse link
G Aldoa aldolase, fructose-bisphosphate A ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 1:198,228,387...198,233,988
Ensembl chr 1:198,228,387...198,233,588
JBrowse link
G Anxa5 annexin A5 IEP RGD PMID:8056721 RGD:7241858 NCBI chr 2:123,162,477...123,194,730
Ensembl chr 2:123,162,461...123,193,130
JBrowse link
G Aplp2 amyloid beta precursor like protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 8:32,298,526...32,328,821
Ensembl chr 8:32,298,532...32,328,839
JBrowse link
G Apob apolipoprotein B ISO RGD PMID:9603795 RGD:1578415 NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997
JBrowse link
G Apoe apolipoprotein E susceptibility ISO DNA:polymorphism:promoter:-219G>T (human) RGD PMID:17006673 RGD:1601238 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Areg amphiregulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr14:18,521,921...18,531,179
Ensembl chr14:18,521,930...18,531,179
JBrowse link
G Arntl aryl hydrocarbon receptor nuclear translocator-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 1:178,039,002...178,137,469
Ensembl chr 1:178,039,063...178,137,465
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 2:204,003,742...204,032,023
Ensembl chr 2:204,003,742...204,032,023
JBrowse link
G Axin2 axin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394407 NCBI chr10:97,212,483...97,238,824
Ensembl chr10:97,212,432...97,239,642
JBrowse link
G Bax BCL2 associated X, apoptosis regulator treatment IEP RGD PMID:22014268 RGD:10054500 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator treatment IEP RGD PMID:22014268 RGD:10054500 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 4:140,703,619...140,709,319
Ensembl chr 4:140,703,619...140,709,319
JBrowse link
G C1qb complement C1q B chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 5:155,246,444...155,251,995
Ensembl chr 5:155,246,447...155,252,003
JBrowse link
G Cacna2d2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 IEP protein:decreased expression:heart RGD PMID:28469787 RGD:13513983 NCBI chr 8:116,154,661...116,285,643
Ensembl chr 8:116,154,736...116,284,985
JBrowse link
G Calr calreticulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr19:25,956,771...25,961,666
Ensembl chr19:25,956,771...25,961,666
JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 2:230,900,907...231,132,207
Ensembl chr 2:230,901,126...231,132,039
JBrowse link
G Canx calnexin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr10:35,800,942...35,833,939
Ensembl chr10:35,800,942...35,833,861
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 IEP
ISO
protein:increased expression:plasma, heart (rat)
CTD Direct Evidence: marker/mechanism
CTD PMID:16214533, PMID:10068207 RGD:8549542 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355
JBrowse link
G Ccna2 cyclin A2 ISO RGD PMID:17382628 RGD:10054468 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccnd1 cyclin D1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccnd2 cyclin D2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 4:159,674,885...159,697,207
Ensembl chr 4:159,674,885...159,697,207
JBrowse link
G Cd36 CD36 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cd38 CD38 molecule IDA
ISO
protein:increased activity:ventricle myocardium
CTD Direct Evidence: marker/mechanism
CTD PMID:16214533, PMID:12111041 RGD:2307243 NCBI chr14:71,714,768...71,754,990
Ensembl chr14:71,715,269...71,754,672
JBrowse link
G Cd40 CD40 molecule treatment IDA RGD PMID:19565716 RGD:11352677 NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704
JBrowse link
G Cd40lg CD40 ligand treatment IDA
IEP
protein:increased expression:myocardium (rat) RGD PMID:19565716, PMID:19204010 RGD:11352677, RGD:11352684 NCBI chr  X:159,703,703...159,714,886
Ensembl chr  X:159,703,578...159,716,562
JBrowse link
G Cdh2 cadherin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr18:8,146,971...8,366,037
Ensembl chr18:8,146,971...8,360,684
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr11:89,008,008...89,009,146
Ensembl chr11:89,008,008...89,009,146
JBrowse link
G Ces3a carboxylesterase 3a ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr19:37,070,705...37,079,411 JBrowse link
G Cirbp cold inducible RNA binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 7:12,400,066...12,405,054
Ensembl chr 7:12,401,207...12,405,022
JBrowse link
G Clec10a C-type lectin domain containing 10A ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr10:56,764,927...56,769,447
Ensembl chr10:56,764,927...56,769,457
JBrowse link
G Cox5b cytochrome c oxidase subunit 5B ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 9:43,259,706...43,262,039
Ensembl chr 9:43,259,709...43,262,040
JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 7:130,395,211...130,404,731
Ensembl chr 7:130,395,194...130,405,347
JBrowse link
G Crk CRK proto-oncogene, adaptor protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr10:63,829,731...63,855,999
Ensembl chr10:63,829,807...63,852,780
JBrowse link
G Crp C-reactive protein IEP
ISO
protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
CTD PMID:11840375, PMID:21122204 RGD:5128547 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Cryab crystallin, alpha B IDA RGD PMID:11945023 RGD:704398 NCBI chr 8:55,178,543...55,182,546
Ensembl chr 8:55,178,289...55,182,545
JBrowse link
G Ctnnb1 catenin beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394407 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Ctsc cathepsin C ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 1:151,918,514...151,949,979
Ensembl chr 1:151,918,571...151,949,983
JBrowse link
G Cttnbp2 cortactin binding protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 4:42,932,897...43,096,454
Ensembl chr 4:42,932,903...43,096,399
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr19:10,644,267...10,654,861
Ensembl chr19:10,644,244...10,653,800
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Dcn decorin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 7:38,742,250...38,782,282
Ensembl chr 7:38,742,051...38,782,323
JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 8:55,062,549...55,087,832
Ensembl chr 8:55,062,551...55,087,832
JBrowse link
G Dnm1l dynamin 1-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr11:88,830,968...88,882,271
Ensembl chr11:88,830,957...88,880,198
JBrowse link
G Dusp1 dual specificity phosphatase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Dusp6 dual specificity phosphatase 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 7:41,475,163...41,479,393
Ensembl chr 7:41,475,163...41,479,392
JBrowse link
G Edn1 endothelin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10462014 PMID:11707688 PMID:16306806 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Ednra endothelin receptor type A ISO RGD PMID:14729387 RGD:1580946 NCBI chr19:33,928,356...33,991,703
Ensembl chr19:33,928,356...33,991,703
JBrowse link
G Ednrb endothelin receptor type B ISO RGD PMID:14729387 RGD:1580946 NCBI chr15:88,004,775...88,036,354
Ensembl chr15:88,006,977...88,036,354
JBrowse link
G Egr2 early growth response 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr20:22,452,170...22,461,018
Ensembl chr20:22,454,463...22,459,025
JBrowse link
G Eif2a eukaryotic translation initiation factor 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:19041636 NCBI chr 2:148,722,343...148,755,781
Ensembl chr 2:148,722,231...148,755,520
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19041636 NCBI chr 4:98,648,513...98,709,695
Ensembl chr 4:98,648,545...98,709,694
JBrowse link
G Eif4e eukaryotic translation initiation factor 4E IDA RGD PMID:16439989 RGD:10401145 NCBI chr 2:243,819,616...243,853,987
Ensembl chr 2:243,820,661...243,852,631
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 IDA RGD PMID:16439989 RGD:10401145 NCBI chr16:68,954,860...68,968,248
Ensembl chr16:68,954,875...68,968,248
JBrowse link
G Eif4g1 eukaryotic translation initiation factor 4 gamma, 1 IEP RGD PMID:16439989 RGD:10401145 NCBI chr11:83,907,659...83,927,683
Ensembl chr11:83,908,109...83,926,524
JBrowse link
G Eln elastin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr12:24,978,478...25,021,864
Ensembl chr12:24,978,483...25,021,863
JBrowse link
G Ensa endosulfine alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 2:197,752,544...197,759,882
Ensembl chr 2:197,752,544...197,759,882
JBrowse link
G Ephx1 epoxide hydrolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29298899 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G Ephx2 epoxide hydrolase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29298899 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 ISO RGD PMID:15685397 RGD:1580988 NCBI chr10:86,367,596...86,391,728
Ensembl chr10:86,367,596...86,391,728
JBrowse link
G F2rl1 F2R like trypsin receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 2:25,222,324...25,235,275
Ensembl chr 2:25,222,328...25,235,275
JBrowse link
G F3 coagulation factor III, tissue factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:16286589 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G F5 coagulation factor V ISO DNA:mutation, haplotype: :1691G>A (human) RGD PMID:19524925 RGD:4892673 NCBI chr13:82,479,997...82,535,540
Ensembl chr13:82,479,998...82,535,534
JBrowse link
G Fabp5 fatty acid binding protein 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 2:93,981,662...93,985,322
Ensembl chr 2:93,981,656...93,985,378
JBrowse link
G Fev FEV transcription factor, ETS family member ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 9:82,142,981...82,146,855
Ensembl chr 9:82,142,981...82,146,874
JBrowse link
G Fez2 fasciculation and elongation protein zeta 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 6:963,903...1,003,955
Ensembl chr 6:963,907...1,004,001
JBrowse link
G Fgf1 fibroblast growth factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr18:32,273,830...32,359,831
Ensembl chr18:32,273,770...32,359,824
JBrowse link
G Fgf2 fibroblast growth factor 2 ISO CTD Direct Evidence: therapeutic CTD PMID:12173832 PMID:14583313 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Fxyd1 FXYD domain-containing ion transport regulator 1 IDA RGD PMID:14597563 RGD:9685466 NCBI chr 1:89,484,197...89,488,279
Ensembl chr 1:89,484,199...89,488,223
JBrowse link
G Gas5 growth arrest specific 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr13:78,852,523...78,855,844 JBrowse link
G Gatm glycine amidinotransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 3:114,711,570...114,728,155
Ensembl chr 3:114,711,562...114,728,410
JBrowse link
G Gbp2 guanylate binding protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 2:248,276,795...248,293,784
Ensembl chr 2:248,276,709...248,293,784
JBrowse link
G Gch1 GTP cyclohydrolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr15:23,935,011...23,968,971
Ensembl chr15:23,934,585...23,969,011
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gdf15 growth differentiation factor 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978
JBrowse link
G Ghr growth hormone receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 2:53,149,225...53,413,954
Ensembl chr 2:53,150,370...53,413,638
JBrowse link
G Ghrl ghrelin and obestatin prepropeptide disease_progression
treatment
IEP
ISO
mRNA,protein:increased expression:plasma,myocardia: RGD PMID:16626506, PMID:16626506 RGD:12907503, RGD:12907503 NCBI chr 4:145,674,157...145,678,066
Ensembl chr 4:145,674,157...145,678,066
JBrowse link
G Ghsr growth hormone secretagogue receptor IEP mRNA,protein:increased expression,increased activity:myocardia: RGD PMID:16626506 RGD:12907503 NCBI chr 2:113,065,953...113,071,265
Ensembl chr 2:113,066,885...113,070,261
JBrowse link
G Gk glycerol kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr  X:54,227,291...54,303,897
Ensembl chr  X:54,227,397...54,303,864
JBrowse link
G Gna12 G protein subunit alpha 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr12:15,890,202...15,971,212
Ensembl chr12:15,890,170...15,971,212
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 9:27,366,404...27,381,004
Ensembl chr 9:27,368,272...27,452,902
JBrowse link
G Gstm2 glutathione S-transferase mu 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 2:210,778,041...210,782,807
Ensembl chr 2:210,720,704...210,782,856
JBrowse link
G Gstp1 glutathione S-transferase pi 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Gyg1 glycogenin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 2:104,916,734...104,958,219
Ensembl chr 2:104,916,738...104,958,034
JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 6:27,589,840...27,628,921
Ensembl chr 6:27,589,657...27,629,175
JBrowse link
G Hfe homeostatic iron regulator susceptibility ISO RGD PMID:11545759 RGD:1582695 NCBI chr17:43,661,276...43,669,327
Ensembl chr17:43,661,222...43,669,985
JBrowse link
G Hgf hepatocyte growth factor ISO CTD Direct Evidence: therapeutic CTD PMID:12447174 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha IEP mRNA, protein:increased expression:myocardium (rat) RGD PMID:17335664 RGD:9068465 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hivep2 HIVEP zinc finger 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 1:8,129,354...8,333,890
Ensembl chr 1:8,310,577...8,333,885
JBrowse link
G Hk1 hexokinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr20:31,911,460...31,979,780
Ensembl chr20:31,912,262...31,956,649
JBrowse link
G Hk2 hexokinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 4:113,559,396...113,609,897
Ensembl chr 4:113,559,427...113,610,243
JBrowse link
G Hmgb1 high mobility group box 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 2:200,452,623...200,480,785
Ensembl chr 2:200,452,624...200,479,423
JBrowse link
G Hmox1 heme oxygenase 1 susceptibility ISO
IEP
CTD Direct Evidence: marker/mechanism CTD PMID:16214533, PMID:15064108, PMID:15734859 RGD:1598399, RGD:1582713 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 6:99,433,575...99,436,288
Ensembl chr 6:99,433,550...99,436,289
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr18:27,731,072...27,749,235
Ensembl chr18:27,731,072...27,749,235
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 IEP protein:increased expression:heart RGD PMID:12872233 RGD:1624250 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 3:148,214,623...148,216,715
Ensembl chr 3:148,215,540...148,216,718
JBrowse link
G Id3 inhibitor of DNA binding 3, HLH protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 5:154,489,603...154,491,172
Ensembl chr 5:154,489,590...154,491,223
JBrowse link
G Ifngr1 interferon gamma receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 1:15,062,380...15,080,815
Ensembl chr 1:15,062,432...15,080,907
JBrowse link
G Igf1 insulin-like growth factor 1 severity ISO
IDA
CTD Direct Evidence: marker/mechanism CTD PMID:16214533, PMID:16793032, PMID:16698918 RGD:1598425, RGD:1598426 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr14:87,457,647...87,465,374
Ensembl chr14:87,457,647...87,465,374
JBrowse link
G Il1a interleukin 1 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16286589 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Il6st interleukin 6 signal transducer ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 2:44,279,199...44,319,427
Ensembl chr 2:44,289,393...44,314,944
JBrowse link
G Irf1 interferon regulatory factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr10:39,109,530...39,116,532
Ensembl chr10:39,109,522...39,116,531
JBrowse link
G Itgav integrin subunit alpha V ISO RGD PMID:11997283 RGD:1582453 NCBI chr 3:71,113,269...71,205,958
Ensembl chr 3:71,114,100...71,202,411
JBrowse link
G Jak2 Janus kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15746188 PMID:16214533 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr19:26,092,972...26,094,756
Ensembl chr19:26,092,974...26,094,756
JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 IEP RGD PMID:26591689 RGD:12790977 NCBI chr 1:102,103,093...102,107,134
Ensembl chr 1:102,103,094...102,106,127
JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 IEP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:16214533, PMID:9399952, PMID:26591689 RGD:1598652, RGD:12790977 NCBI chr 4:176,783,287...176,789,143
Ensembl chr 4:176,782,498...176,789,304
JBrowse link
G Kcnk2 potassium two pore domain channel subfamily K member 2 IEP mRNA:increased expression:heart left ventricle, epicardium, endocardium (rat) RGD PMID:24705172 RGD:9831164 NCBI chr13:107,690,111...107,886,476
Ensembl chr13:107,690,087...107,886,476
JBrowse link
G Kcnmb1 potassium calcium-activated channel subfamily M regulatory beta subunit 1 no_association ISO RGD PMID:16155733 RGD:1581719 NCBI chr10:18,910,586...18,922,856
Ensembl chr10:18,906,010...18,919,639
JBrowse link
G Kdr kinase insert domain receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183
JBrowse link
G Kitlg KIT ligand ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 7:42,269,784...42,351,054
Ensembl chr 7:42,269,784...42,351,054
JBrowse link
G Klf4 Kruppel like factor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 5:72,283,311...72,287,669
Ensembl chr 5:72,283,313...72,287,669
JBrowse link
G Lepr leptin receptor susceptibility ISO DNA:polymorphism: :p.Q223R (human) RGD PMID:19337797 RGD:2311129 NCBI chr 5:120,503,475...120,682,281
Ensembl chr 5:120,564,645...120,682,221
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta IDA RGD PMID:12371906 RGD:629541 NCBI chr19:53,635,449...53,643,970
Ensembl chr19:53,629,779...53,646,058
JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 IDA RGD PMID:20550965 RGD:7243113 NCBI chr10:45,089,455...45,110,802
Ensembl chr10:47,182,433...47,203,753
JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr17:56,109,403...56,129,925
Ensembl chr17:56,109,549...56,129,919
JBrowse link
G Mapk14 mitogen activated protein kinase 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Mapre1 microtubule-associated protein, RP/EB family, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 3:149,221,346...149,249,469
Ensembl chr 3:149,221,377...149,249,273
JBrowse link
G Mb myoglobin susceptibility IDA
ISO
RGD PMID:12935692, PMID:15762290 RGD:1582426, RGD:1582393 NCBI chr 7:118,101,633...118,108,864
Ensembl chr 7:118,101,634...118,108,864
JBrowse link
G Meox2 mesenchyme homeobox 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 6:56,625,768...56,689,195
Ensembl chr 6:56,625,650...56,689,238
JBrowse link
G Mfn1 mitofusin 1 treatment IEP RGD PMID:27491814 RGD:12910831 NCBI chr 2:118,929,738...118,971,689
Ensembl chr 2:118,929,738...118,973,698
JBrowse link
G Mfn2 mitofusin 2 treatment IEP RGD PMID:27491814 RGD:12910831 NCBI chr 5:164,684,244...164,715,414
Ensembl chr 5:164,684,509...164,714,145
JBrowse link
G Mpo myeloperoxidase ISO Acute Coronary Syndrome; protein:increased expression:plasma RGD PMID:21226709 RGD:5130961 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Msn moesin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr  X:65,226,834...65,294,192
Ensembl chr  X:65,226,748...65,295,810
JBrowse link
G Msr1 macrophage scavenger receptor 1 disease_progression ISO mRNA:increased expression:blood, mononuclear cell RGD PMID:17945237 RGD:2306126 NCBI chr16:56,817,714...56,900,025
Ensembl chr16:56,813,791...56,900,052
JBrowse link
G Mx2 MX dynamin like GTPase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr11:38,035,306...38,066,185
Ensembl chr11:38,035,450...38,059,950
JBrowse link
G Ncl nucleolin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 9:93,369,119...93,377,643
Ensembl chr 9:93,368,932...93,377,643
JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 8:79,323,408...79,408,842
Ensembl chr 8:79,323,408...79,408,833
JBrowse link
G Nfkbia NFKB inhibitor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nos3 nitric oxide synthase 3 susceptibility ISO DNA:duplication, snp:intron, cds:g.IVS4?-?+27, p.E298D (human)
ClinVar Annotator: match by term: Ischemic heart disease, susceptibility to
CTD Direct Evidence: therapeutic
ClinVar
CTD
PMID:9737779 PMID:9894802 PMID:10475066 PMID:10510054 PMID:10514107 PMID:11026457 PMID:11354626 PMID:11394896 PMID:11745998 PMID:12354446 PMID:15007011 PMID:16059745 PMID:16813604 PMID:17165044 PMID:24033266, PMID:15007011 RGD:7777100 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Nppa natriuretic peptide A ISO CTD Direct Evidence: marker/mechanism CTD PMID:1830552 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705
JBrowse link
G Nptn neuroplastin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 8:63,379,062...63,445,694
Ensembl chr 8:63,379,087...63,445,686
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 7:142,899,358...142,920,216
Ensembl chr 7:142,905,758...142,920,216
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase treatment IEP RGD PMID:27491814 RGD:12910831 NCBI chr11:74,717,600...74,793,902
Ensembl chr11:74,720,254...74,793,803
JBrowse link
G P4hb prolyl 4-hydroxylase subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr10:109,736,459...109,748,070
Ensembl chr10:109,736,458...109,747,987
JBrowse link
G Pde4b phosphodiesterase 4B ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 5:121,759,236...122,136,814
Ensembl chr 5:121,952,977...122,136,814
JBrowse link
G Pdha1 pyruvate dehydrogenase E1 subunit alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr  X:37,329,779...37,343,410
Ensembl chr  X:37,329,779...37,343,410
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 4:30,546,772...30,556,774
Ensembl chr 4:30,546,664...30,556,814
JBrowse link
G Pdlim5 PDZ and LIM domain 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 2:247,815,214...247,989,198
Ensembl chr 2:247,818,243...247,988,462
JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr12:45,026,948...45,031,148
Ensembl chr12:45,026,886...45,031,145
JBrowse link
G Penk proenkephalin treatment IEP RGD PMID:21247719 RGD:10003103 NCBI chr 5:17,056,412...17,061,762
Ensembl chr 5:17,056,419...17,061,837
JBrowse link
G Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr17:70,632,778...70,713,736
Ensembl chr17:70,684,134...70,713,726
JBrowse link
G Pfkm phosphofructokinase, muscle ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 7:139,702,066...139,722,132
Ensembl chr 7:139,685,573...139,722,132
JBrowse link
G Pgf placental growth factor ISO RGD PMID:18192038 RGD:6483613 NCBI chr 6:108,994,016...109,004,598
Ensembl chr 6:108,994,018...109,004,598
JBrowse link
G Pgm1 phosphoglucomutase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 5:118,743,632...118,803,055
Ensembl chr 5:118,743,632...118,803,055
JBrowse link
G Pla2g2a phospholipase A2 group IIA ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 5:157,282,650...157,285,295
Ensembl chr 5:157,282,669...157,285,328
JBrowse link
G Plcd1 phospholipase C, delta 1 IEP protein:decreased expression:heart RGD PMID:15276620 RGD:2300429 NCBI chr 8:127,753,514...127,782,070
Ensembl chr 8:127,753,539...127,782,070
JBrowse link
G Pomc proopiomelanocortin ISO CTD Direct Evidence: marker/mechanism CTD PMID:10908253 NCBI chr 6:28,382,937...28,388,771
Ensembl chr 6:28,382,962...28,388,967
JBrowse link
G Ppat phosphoribosyl pyrophosphate amidotransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr14:33,580,541...33,614,919
Ensembl chr14:33,580,541...33,614,919
JBrowse link
G Ppm1b protein phosphatase, Mg2+/Mn2+ dependent, 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 6:8,219,385...8,280,127
Ensembl chr 6:8,218,696...8,280,124
JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr10:37,534,449...37,554,861
Ensembl chr10:37,535,871...37,554,664
JBrowse link
G Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha IDA
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:16214533, PMID:16214533 RGD:1580707 NCBI chr14:100,311,224...100,360,879
Ensembl chr14:100,311,173...100,360,879
JBrowse link
G Prdx6 peroxiredoxin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr13:79,077,567...79,088,113
Ensembl chr13:79,077,033...79,088,127
JBrowse link
G Prkcd protein kinase C, delta IEP mRNA, protein:increased expression, altered phosphorylation:heart RGD PMID:16924416 RGD:1642550 NCBI chr16:6,655,131...6,675,746
Ensembl chr16:6,655,120...6,675,746
JBrowse link
G Prkce protein kinase C, epsilon ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 6:9,483,400...9,973,396
Ensembl chr 6:9,790,422...9,973,396
JBrowse link
G Psmb5 proteasome 20S subunit beta 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr15:33,259,039...33,263,634
Ensembl chr15:33,259,043...33,263,659
JBrowse link
G Ptpra protein tyrosine phosphatase, receptor type, A ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 3:122,976,066...123,084,585
Ensembl chr 3:122,976,104...123,084,863
JBrowse link
G Pygb glycogen phosphorylase B ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 3:146,581,063...146,629,504
Ensembl chr 3:146,582,752...146,634,535
JBrowse link
G Pygm glycogen phosphorylase, muscle associated IDA RGD PMID:10498852 RGD:1599991 NCBI chr 1:221,756,325...221,771,142
Ensembl chr 1:221,756,286...221,771,143
JBrowse link
G Rab12 RAB12, member RAS oncogene family ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 9:114,683,985...114,709,613
Ensembl chr 9:114,684,039...114,709,546
JBrowse link
G Rab1b RAB1B, member RAS oncogene family ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 1:220,483,529...220,491,469
Ensembl chr 1:220,480,834...220,491,469
JBrowse link
G Rab5a RAB5A, member RAS oncogene family ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 9:5,910...6,065 JBrowse link
G Rab7a RAB7A, member RAS oncogene family ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 4:119,910,461...119,963,065
Ensembl chr 4:119,910,478...119,959,173
JBrowse link
G Ralbp1 ralA binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 9:113,579,107...113,598,477
Ensembl chr 9:113,579,107...113,598,480
JBrowse link
G Ramp2 receptor activity modifying protein 2 IEP mRNA:increased expression:ventricle myocardium RGD PMID:16987513 RGD:1642684 NCBI chr10:89,166,170...89,168,962
Ensembl chr10:89,166,890...89,168,965
JBrowse link
G Rgcc regulator of cell cycle ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr15:61,551,861...61,564,695
Ensembl chr15:61,551,861...61,564,695
JBrowse link
G Rhoc ras homolog family member C ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 2:207,271,692...207,278,010
Ensembl chr 2:207,271,853...207,279,314
JBrowse link
G Rln3 relaxin 3 ISO CTD Direct Evidence: therapeutic CTD PMID:16112403 NCBI chr19:25,164,497...25,166,528
Ensembl chr19:25,164,497...25,166,528
JBrowse link
G Rpl17 ribosomal protein L17 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr18:70,969,733...70,972,839
Ensembl chr18:70,970,596...70,975,494
JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 6:45,655,947...45,669,083
Ensembl chr 6:45,655,954...45,669,148
JBrowse link
G RT1-N3 RT1 class Ib, locus N3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr20:3,166,793...3,170,945
Ensembl chr20:3,167,079...3,170,945
JBrowse link
G RT1-S3 RT1 class Ib, locus S3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr20:3,176,124...3,180,825
Ensembl chr20:3,176,107...3,179,818
JBrowse link
G Rtn1 reticulon 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 6:94,951,016...95,177,477
Ensembl chr 6:94,951,020...95,061,174
JBrowse link
G Rxrg retinoid X receptor gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr13:85,818,473...85,868,555
Ensembl chr13:85,818,427...85,868,552
JBrowse link
G Ryr2 ryanodine receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr17:65,533,998...65,955,606
Ensembl chr17:65,535,403...65,955,606
JBrowse link
G S100a1 S100 calcium binding protein A1 ISO protein:increased expression:serum (human) RGD PMID:10924368 RGD:1579977 NCBI chr 2:189,900,505...189,905,348
Ensembl chr 2:189,900,667...189,903,219
JBrowse link
G Sele selectin E ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr13:82,355,234...82,365,323
Ensembl chr13:82,355,471...82,365,341
JBrowse link
G Selp selectin P ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr13:82,428,914...82,464,629
Ensembl chr13:82,429,063...82,464,628
JBrowse link
G Serpina1 serpin family A member 1 ISO associated with Aortic Aneurysm, Abdominal;DNA:polymorphism: :p.E342K (human) RGD PMID:10063411 RGD:1643148 NCBI chr 6:127,610,241...127,632,265
Ensembl chr 6:127,610,243...127,632,265
JBrowse link
G Serpinf1 serpin family F member 1 ISO associated with chronic kidney disease;protein:increased expression:blood (human) RGD PMID:11045282 RGD:30296653 NCBI chr10:62,241,750...62,254,145
Ensembl chr10:62,241,756...62,254,287
JBrowse link
G Sfrp4 secreted frizzled-related protein 4 IEP RGD PMID:20528676 RGD:4107721 NCBI chr17:47,383,983...47,394,065
Ensembl chr17:47,297,489...47,394,328
JBrowse link
G Slc6a6 solute carrier family 6 member 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 4:123,638,619...123,713,469
Ensembl chr 4:123,642,210...123,713,464
JBrowse link
G Slc8a1 solute carrier family 8 member A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 6:4,244,076...4,564,262
Ensembl chr 6:4,258,991...4,520,604
JBrowse link
G Slc9a1 solute carrier family 9 member A1 IDA RGD PMID:17356886 RGD:1625560 NCBI chr 5:151,573,122...151,626,360
Ensembl chr 5:151,573,092...151,627,316
JBrowse link
G Snap23 synaptosome associated protein 23 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 3:112,333,972...112,362,960 JBrowse link
G Socs3 suppressor of cytokine signaling 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr10:106,973,863...106,976,969
Ensembl chr10:106,975,178...106,976,040
JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533, PMID:15681709 RGD:1581233 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sod3 superoxide dismutase 3 IDA
ISO
ClinVar Annotator: match by term: Superoxide dismutase, elevated extracellular ClinVar PMID:7662997 PMID:8034674 PMID:14662715, PMID:16840738 RGD:1580843 NCBI chr14:60,958,583...60,971,143
Ensembl chr14:60,958,592...60,964,324
JBrowse link
G Sparc secreted protein acidic and cysteine rich ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr10:40,742,390...40,764,232
Ensembl chr10:40,742,400...40,764,185
JBrowse link
G Stat5a signal transducer and activator of transcription 5A ISO CTD Direct Evidence: marker/mechanism CTD PMID:15746188 NCBI chr10:88,764,732...88,789,060
Ensembl chr10:88,764,732...88,789,057
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 1:198,100,586...198,104,106
Ensembl chr 1:198,100,586...198,104,109
JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr20:3,979,302...3,989,669
Ensembl chr20:3,979,035...3,989,669
JBrowse link
G Tcf7l2 transcription factor 7 like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394407 NCBI chr 1:276,686,911...276,730,517
Ensembl chr 1:276,659,542...276,730,514
Ensembl chr 1:276,659,542...276,730,514
JBrowse link
G Tfrc transferrin receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr11:71,397,423...71,419,263
Ensembl chr11:71,397,383...71,419,223
JBrowse link
G Tgoln2 trans-golgi network protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 4:100,475,415...100,483,229
Ensembl chr 4:100,475,416...100,483,168
JBrowse link
G Tle4 TLE family member 4, transcriptional corepressor ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 1:231,394,606...231,531,396
Ensembl chr 1:231,393,379...231,530,786
JBrowse link
G Tle5 TLE family member 5, transcriptional modulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 7:11,012,843...11,018,156
Ensembl chr 7:11,013,681...11,018,160
JBrowse link
G Tmed2 transmembrane p24 trafficking protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr12:37,471,259...37,480,344
Ensembl chr12:37,471,260...37,480,297
JBrowse link
G Tmpo thymopoietin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 7:31,847,412...31,872,416
Ensembl chr 7:31,847,410...31,872,423
JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 PMID:16775501 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnnt2 troponin T2, cardiac type ISO CTD Direct Evidence: marker/mechanism CTD PMID:10789933 NCBI chr13:52,662,974...52,680,992
Ensembl chr13:52,662,996...52,680,990
JBrowse link
G Ttn titin IDA RGD PMID:12221049 RGD:1580780 NCBI chr 3:63,565,160...63,837,815 JBrowse link
G Tuba1a tubulin, alpha 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 7:140,637,287...140,640,953
Ensembl chr 7:140,637,287...140,640,953
JBrowse link
G Txnip thioredoxin interacting protein IDA RGD PMID:16172122 RGD:1580789 NCBI chr 2:198,683,168...198,686,971
Ensembl chr 2:198,683,159...198,686,974
JBrowse link
G Txnrd1 thioredoxin reductase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link
G Ugcg UDP-glucose ceramide glucosyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 5:76,376,722...76,419,564
Ensembl chr 5:76,386,836...76,419,560
JBrowse link
G Uqcrfs1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr17:35,677,984...35,682,262
Ensembl chr17:35,677,984...35,682,259
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link
G Vegfa vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:9860779 PMID:14503966 PMID:14583313 PMID:15347709 PMID:16214533 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Zeb1 zinc finger E-box binding homeobox 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr17:54,656,627...54,714,920
Ensembl chr17:54,658,463...54,714,914
JBrowse link
G Zfp36 zinc finger protein 36 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 1:85,380,088...85,382,565
Ensembl chr 1:85,380,088...85,382,569
JBrowse link
Acute Coronary Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actg1 actin, gamma 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21751358 NCBI chr10:109,518,429...109,521,288
Ensembl chr 3:75,643,054...75,644,954
Ensembl chr10:75,643,054...75,644,954
JBrowse link
G Ager advanced glycosylation end product-specific receptor ISO protein:increased expression:serum (human) RGD PMID:21663912 RGD:5508825 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Alb albumin treatment ISO RGD PMID:20716836 RGD:11036086 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Arhgdib Rho GDP dissociation inhibitor beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:21751358 NCBI chr 4:170,913,920...170,932,789
Ensembl chr 4:170,913,923...170,932,618
JBrowse link
G Capzb capping actin protein of muscle Z-line subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:21751358 NCBI chr 5:157,642,742...157,742,487
Ensembl chr 5:157,642,751...157,742,478
JBrowse link
G Cd40 CD40 molecule ISO DNA:SNP:5' utr:rs1883832 (human) RGD PMID:21091218 RGD:5490523 NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704
JBrowse link
G Cd40lg CD40 ligand treatment ISO associated with Anxiety Disorders;protein:increased expression:serum RGD PMID:20170788, PMID:31624788 RGD:5490548, RGD:21081509 NCBI chr  X:159,703,703...159,714,886
Ensembl chr  X:159,703,578...159,716,562
JBrowse link
G Ckb creatine kinase B ISO CTD Direct Evidence: marker/mechanism CTD PMID:15966572 NCBI chr 6:136,142,956...136,145,838
Ensembl chr 6:136,142,956...136,145,837
JBrowse link
G Ckm creatine kinase, M-type ISO CTD Direct Evidence: marker/mechanism CTD PMID:15966572 NCBI chr 1:80,321,507...80,331,841
Ensembl chr 1:80,321,585...80,331,841
JBrowse link
G Crp C-reactive protein ISO CTD Direct Evidence: marker/mechanism
protein:increased expression: :
CTD PMID:15966572 PMID:23305094, PMID:18973750, PMID:21794939 RGD:6907401, RGD:9491837 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Eno1 enolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21751358 NCBI chr 5:167,288,223...167,299,610
Ensembl chr 5:167,288,223...167,299,609
JBrowse link
G F12 coagulation factor XII ISO ClinVar Annotator: match by term: FACTOR XII POLYMORPHISM ClinVar PMID:9490684 PMID:11843842 PMID:20303064 PMID:24033266 PMID:25741868 NCBI chr17:9,736,577...9,744,420
Ensembl chr17:9,736,577...9,744,420
JBrowse link
G F2 coagulation factor II ISO RGD PMID:21496882 RGD:5147784 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031
JBrowse link
G Fasn fatty acid synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23305094 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21751358 NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962
JBrowse link
G Gsn gelsolin ISO CTD Direct Evidence: marker/mechanism CTD PMID:21751358 NCBI chr 3:14,456,106...14,508,922
Ensembl chr 3:14,467,330...14,508,911
JBrowse link
G Gstp1 glutathione S-transferase pi 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21751358 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A ISO DNA:SNP: :190G>C(human) RGD PMID:21849784 RGD:7257650 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21751358 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21751358 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23305094 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Itgb3 integrin subunit beta 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15840736 NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410
JBrowse link
G Ldhb lactate dehydrogenase B ISO CTD Direct Evidence: marker/mechanism CTD PMID:21751358 NCBI chr 4:176,701,980...176,719,999
Ensembl chr 4:176,701,983...176,720,012
JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20981132 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Pappa1 pappalysin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11586954 NCBI chr 5:80,919,932...81,153,904
Ensembl chr 5:80,920,568...81,150,940
JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21751358 NCBI chr 3:113,376,983...113,400,707
Ensembl chr 3:113,376,983...113,400,707
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 ISO protein:increased expression:coronary artery, intima (human) RGD PMID:22336504 RGD:6767292 NCBI chr10:94,850,971...94,913,202 JBrowse link
G Pla2g7 phospholipase A2 group VII disease_progression ISO RGD PMID:22024276 RGD:6482773 NCBI chr 9:19,935,754...19,978,013
Ensembl chr 9:19,935,768...19,978,013
JBrowse link
G Pon1 paraoxonase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26241956 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Psmb1 proteasome 20S subunit beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21751358 NCBI chr 1:57,470,878...57,491,359
Ensembl chr 1:57,470,632...57,489,727
JBrowse link
G Rab7b Rab7b, member RAS oncogene family ISO CTD Direct Evidence: marker/mechanism CTD PMID:21751358 NCBI chr13:48,456,143...48,483,714
Ensembl chr13:48,455,923...48,482,138
JBrowse link
G S100b S100 calcium binding protein B ISO protein:increased expression:serum RGD PMID:21663912 RGD:5508825 NCBI chr20:13,130,633...13,142,856
Ensembl chr20:13,130,636...13,142,856
JBrowse link
G Serpinc1 serpin family C member 1 ISO CTD Direct Evidence: therapeutic CTD PMID:7923645 NCBI chr13:78,806,107...78,820,375
Ensembl chr13:78,805,347...78,833,192
JBrowse link
G Slc34a1 solute carrier family 34 member 1 ISO ClinVar Annotator: match by term: FACTOR XII POLYMORPHISM ClinVar PMID:9490684 PMID:11843842 PMID:20303064 PMID:24033266 PMID:25741868 NCBI chr17:9,747,766...9,762,739
Ensembl chr17:9,747,752...9,762,813
JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21751358 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Tlr4 toll-like receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20981132 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20981132 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnni3 troponin I3, cardiac type ISO CTD Direct Evidence: marker/mechanism CTD PMID:15966572 NCBI chr 1:72,882,806...72,886,490
Ensembl chr 1:72,882,806...72,886,488
JBrowse link
G Tnnt2 troponin T2, cardiac type ISO CTD Direct Evidence: marker/mechanism CTD PMID:15966572 NCBI chr13:52,662,974...52,680,992
Ensembl chr13:52,662,996...52,680,990
JBrowse link
G Tpm4 tropomyosin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21751358 NCBI chr16:19,385,810...19,399,851
Ensembl chr16:19,385,736...19,399,903
JBrowse link
G Tuba1c tubulin, alpha 1C ISO CTD Direct Evidence: marker/mechanism CTD PMID:21751358 NCBI chr 7:140,716,113...140,723,717
Ensembl chr 7:140,716,113...140,723,714
JBrowse link
G Tubb1 tubulin, beta 1 class VI ISO CTD Direct Evidence: marker/mechanism CTD PMID:21751358 NCBI chr 3:172,550,252...172,558,089
Ensembl chr 3:172,550,258...172,558,114
JBrowse link
G Vcl vinculin ISO CTD Direct Evidence: marker/mechanism CTD PMID:21751358 NCBI chr15:3,455,211...3,544,738
Ensembl chr15:3,455,211...3,544,702
JBrowse link
G Vim vimentin ISO CTD Direct Evidence: marker/mechanism CTD PMID:21751358 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
JBrowse link
acute myocardial infarction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 ISO RGD PMID:26476955 RGD:11552746 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G Cacng4 calcium voltage-gated channel auxiliary subunit gamma 4 ISO mRNA:decreased expression:blood: RGD PMID:27746059 RGD:13524557 NCBI chr10:95,954,160...96,015,484
Ensembl chr10:95,951,234...96,015,499
JBrowse link
G Casp3 caspase 3 treatment IEP RGD PMID:26550220 RGD:13782284 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp7 caspase 7 treatment IEP RGD PMID:26550220 RGD:13782284 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta treatment IEP RGD PMID:26591365 RGD:13792778 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 IEP RGD PMID:24837094 RGD:40813741 NCBI chr 9:47,133,483...47,184,316
Ensembl chr 9:47,134,034...47,182,170
JBrowse link
G Il33 interleukin 33 IEP RGD PMID:24837094 RGD:40813741 NCBI chr 1:248,112,611...248,147,030
Ensembl chr 1:248,132,090...248,147,029
JBrowse link
G Mir146a microRNA 146a ISO miRNA:increased expression:peripheral blood mononuclear cell, plasma RGD PMID:31866771 RGD:21081515 NCBI chr10:28,962,476...28,962,570
Ensembl chr10:28,962,476...28,962,570
JBrowse link
G Mir155 microRNA 155 ISO miRNA:decreased expression:peripheral blood mononuclear cell, plasma RGD PMID:31866771 RGD:21081515 NCBI chr11:24,176,603...24,176,667
Ensembl chr11:24,176,603...24,176,667
JBrowse link
G Mir21 microRNA 21 ISO miRNA:increased expression:peripheral blood mononuclear cell, plasma RGD PMID:31866771 RGD:21081515 NCBI chr10:73,902,210...73,902,301
Ensembl chr10:73,902,210...73,902,301
JBrowse link
G Mir223 microRNA 223 treatment IMP RGD PMID:29689569 RGD:25823140 NCBI chr  X:65,367,812...65,367,921
Ensembl chr  X:65,367,812...65,367,921
JBrowse link
G Serping1 serpin family G member 1 ISO
IEP
mRNA:increased expression:heart RGD PMID:26476955, PMID:26476955 RGD:11552746, RGD:11552746 NCBI chr 3:72,161,230...72,171,109
Ensembl chr 3:72,161,189...72,171,078
JBrowse link
Angina Pectoris term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 ISO RGD PMID:11527135 RGD:5129114 NCBI chr 1:277,537,585...277,538,985
Ensembl chr 1:277,537,585...277,538,985
JBrowse link
G Adrb2 adrenoceptor beta 2 ISO RGD PMID:11527135 RGD:5129114 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834
JBrowse link
G Avp arginine vasopressin ISO CTD Direct Evidence: marker/mechanism CTD PMID:11128043 PMID:11791009 NCBI chr 3:123,117,482...123,119,460
Ensembl chr 3:123,117,492...123,119,460
JBrowse link
G Cpb2 carboxypeptidase B2 ISO RGD PMID:12624641 RGD:1598479 NCBI chr15:57,290,849...57,339,762
Ensembl chr15:57,290,849...57,339,760
JBrowse link
G Mir146a microRNA 146a ISO miRNA:increased expression:peripheral blood mononuclear cell, plasma RGD PMID:31866771 RGD:21081515 NCBI chr10:28,962,476...28,962,570
Ensembl chr10:28,962,476...28,962,570
JBrowse link
G Mir155 microRNA 155 ISO miRNA:decreased expression:peripheral blood mononuclear cell, plasma RGD PMID:31866771 RGD:21081515 NCBI chr11:24,176,603...24,176,667
Ensembl chr11:24,176,603...24,176,667
JBrowse link
G Mir21 microRNA 21 ISO miRNA:increased expression:peripheral blood mononuclear cell, plasma RGD PMID:31866771 RGD:21081515 NCBI chr10:73,902,210...73,902,301
Ensembl chr10:73,902,210...73,902,301
JBrowse link
G Plau plasminogen activator, urokinase ISO CTD Direct Evidence: therapeutic CTD PMID:1730212 NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819
JBrowse link
G Spp1 secreted phosphoprotein 1 ISO RGD PMID:16421174 RGD:1581390 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
Angina, Stable term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F7 coagulation factor VII ISO protein:increased activity:plasma (human) RGD PMID:17357481 RGD:11049525 NCBI chr16:81,824,610...81,834,923
Ensembl chr16:81,824,111...81,834,945
JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20981132 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Tlr4 toll-like receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20981132 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20981132 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
anterolateral myocardial infarction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edn1 endothelin 1 ISO protein:increased expression:aortic root, coronary sinus, plasma (human) RGD PMID:12581682 RGD:8661757 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Serpine1 serpin family E member 1 disease_progression ISO protein:decreased expression, decreased activity:heart: RGD PMID:12615902, PMID:12615902 RGD:13208541, RGD:13208541 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
Cardiac Allograft Vasculopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F3 coagulation factor III, tissue factor IEP RGD PMID:9916935 RGD:11341701 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G Pdgfd platelet derived growth factor D ISO RGD PMID:19213942 RGD:9854642 NCBI chr 8:4,441,010...4,666,754
Ensembl chr 8:4,440,876...4,669,014
JBrowse link
Cardiogenic Shock term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epo erythropoietin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19337937 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Plat plasminogen activator, tissue type ISO CTD Direct Evidence: therapeutic CTD PMID:1430592 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21062213 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
coronary aneurysm term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing ISO associated with Mucocutaneous Lymph Node Syndrome;protein:increased expression:serum RGD PMID:22683371 RGD:8694456 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Gja1 gap junction protein, alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15548583 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Itpkc inositol-trisphosphate 3-kinase C ISO CTD Direct Evidence: marker/mechanism CTD PMID:18084290 NCBI chr 1:84,018,857...84,040,433
Ensembl chr 1:84,018,859...84,040,433
JBrowse link
G Mill1 MHC I like leukocyte 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10899738 NCBI chr 1:79,631,266...79,657,943
Ensembl chr 1:79,631,668...79,657,941
JBrowse link
G Mmp12 matrix metallopeptidase 12 susceptibility ISO RGD PMID:12103254 RGD:1582363 NCBI chr 8:5,594,717...5,616,494
Ensembl chr 8:5,606,592...5,616,493
JBrowse link
coronary artery disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 ISO RGD
GAD
PMID:11086027, PMID:15118671 RGD:1600951, RGD:1331525 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015
JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 ISO DNA:nonsense mutation:exon:p.R1141X (3421C>T) (human) RGD PMID:12176944 RGD:11038788 NCBI chr 1:101,954,786...102,013,252
Ensembl chr 1:101,959,540...102,013,243
JBrowse link
G Abcc9 ATP binding cassette subfamily C member 9 ISS OMIM:300464 | OMIM:607339 | OMIM:608316 | OMIM:608318 | OMIM:608320 | OMIM:608901 | OMIM:610938 | OMIM:610947 | OMIM:611139 | OMIM:612030 | OMIM:614293 | OMIM:614466 MouseDO NCBI chr 4:176,806,098...176,928,540
Ensembl chr 4:176,805,431...176,922,424
JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11099417 PMID:11138003 NCBI chr 6:7,935,771...7,961,207
Ensembl chr 6:7,935,771...7,961,207
JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11099417 NCBI chr 6:7,961,413...7,980,708
Ensembl chr 6:7,961,413...7,980,708
JBrowse link
G Abo ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr 3:4,374,679...4,394,374
Ensembl chr 3:4,374,602...4,394,428
JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 susceptibility ISO DNA:polymorphisms: :41A>G, 734C>T, IVS4-57_58ins48bp RGD PMID:16195894 RGD:1601112 NCBI chr 1:47,972,399...47,992,654
Ensembl chr 1:47,972,399...47,992,653
JBrowse link
G Ace angiotensin I converting enzyme susceptibility ISO DNA:deletion:intron:IVS16+1464-1751del (human)
CTD Direct Evidence: marker/mechanism
CTD PMID:14989558, PMID:12975417, PMID:15118671 RGD:1566498, RGD:1331525 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Acp1 acid phosphatase 1 ISO RGD PMID:19246900 RGD:2313179 NCBI chr 6:49,836,064...49,851,714
Ensembl chr 6:49,836,075...49,851,714
JBrowse link
G Adamts7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr 8:97,535,777...97,575,661
Ensembl chr 8:97,535,777...97,575,655
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO protein:decreased expression:adipose tissue RGD PMID:17878891 RGD:5686802 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Adrb3 adrenoceptor beta 3 no_association ISO DNA:missense mutation:cds:p.W64R (human)
DNA:missense mutation:cds:p.W64R rs4994 (human)
RGD PMID:9126344, PMID:11229427 RGD:1559325, RGD:5684412 NCBI chr16:69,003,541...69,006,632
Ensembl chr16:69,003,868...69,006,632
JBrowse link
G Adtrp androgen-dependent TFPI-regulating protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378986 NCBI chr17:22,619,913...22,688,296
Ensembl chr17:22,619,891...22,688,307
JBrowse link
G Ager advanced glycosylation end product-specific receptor susceptibility ISO DNA:polymorphism:cds:p.G82S (human)
associated with Mucocutaneous Lymph Node Syndrome
RGD PMID:20668462, PMID:22337222 RGD:6767569, RGD:8695960 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Agt angiotensinogen ISO GAD PMID:15118671 RGD:1331525 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Agtr1a angiotensin II receptor, type 1a susceptibility ISO DNA:polymorphism:3' utr:1166A>C RGD
GAD
PMID:12975417, PMID:15118671 RGD:1566498, RGD:1331525 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077
JBrowse link
G Ahsg alpha-2-HS-glycoprotein susceptibility ISO associated with Diabetes Mellitus, Type 2;DNA:SNPs RGD PMID:17062776, PMID:17062776 RGD:1625792, RGD:1625792 NCBI chr11:81,711,269...81,717,594 JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO RGD PMID:18054314 RGD:5509083 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein ISO DNA:snps:multiple (human) RGD PMID:19596330 RGD:2313883 NCBI chr12:6,854,930...6,879,112
Ensembl chr12:6,854,920...6,879,154
JBrowse link
G Angptl4 angiopoietin-like 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27135400 NCBI chr 7:18,627,814...18,634,043
Ensembl chr 7:18,627,808...18,634,079
JBrowse link
G Anks1a ankyrin repeat and sterile alpha motif domain containing 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr20:7,484,550...7,636,498
Ensembl chr20:7,484,550...7,636,497
JBrowse link
G Apcs amyloid P component, serum ISO CTD Direct Evidence: marker/mechanism CTD PMID:12714198 NCBI chr13:91,426,621...91,427,417
Ensembl chr13:91,426,479...91,427,575
JBrowse link
G Aph1b aph-1 homolog B, gamma secretase subunit ISO DNA:SNP:CDS:p.F217L (rs1047552) (human) RGD PMID:18987747 RGD:13703124 NCBI chr 8:72,508,008...72,598,921
Ensembl chr 8:72,476,425...72,629,265
JBrowse link
G Apoa1 apolipoprotein A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27135400, PMID:2128269, PMID:15118671 RGD:1601188, RGD:1331525 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Apoa2 apolipoprotein A2 ISO protein:decreased expression:serum RGD PMID:17923573 RGD:2313956 NCBI chr13:89,596,872...89,598,805
Ensembl chr13:89,597,138...89,598,802
JBrowse link
G Apoa5 apolipoprotein A5 no_association ISO DNA:polymorphism:promoter:-1131T>C (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphism:promoter:-1131T>C, c.56C>G (human)
CTD PMID:24097064, PMID:15177130, PMID:15306190 RGD:2313322, RGD:1578412 NCBI chr 8:50,559,079...50,561,720
Ensembl chr 8:50,559,126...50,561,736
JBrowse link
G Apob apolipoprotein B no_association ISO RGD
GAD
PMID:9585673, PMID:15118671, PMID:1732399 RGD:1578418, RGD:1331525, RGD:1578417 NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997
JBrowse link
G Apoc3 apolipoprotein C3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24097064, PMID:14709372, PMID:15118671, PMID:15059615 RGD:1578443, RGD:1331525, RGD:1626412 NCBI chr 8:50,529,318...50,531,498
Ensembl chr 8:50,529,318...50,531,498
JBrowse link
G Apoe apolipoprotein E susceptibility ISO
IMP
DNA:snp, missense mutation:promoter, cds:g.-219G>T, p.C112R (human)
associated with Diabetes Mellitus, Non-Insulin Dependent;DNA:SNP:promoter:-219G>T (human)
DNA:missense mutation:cds:p.C112R (human)
RGD
GAD
PMID:14563588, PMID:28808185, PMID:15118671, PMID:15059615, PMID:12860263 RGD:1580039, RGD:13703132, RGD:1331525, RGD:1626412, RGD:1578449 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Apom apolipoprotein M susceptibility ISO DNA:SNP:promoter:g.-778T>C(rs805296)(human) RGD PMID:17674965 RGD:2314241 NCBI chr20:5,120,473...5,123,073
Ensembl chr20:5,120,474...5,123,073
JBrowse link
G Ar androgen receptor ISO GAD PMID:15118671 RGD:1331525 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22751097 NCBI chr 7:41,114,606...41,223,138
Ensembl chr 7:41,114,697...41,220,579
JBrowse link
G Bche butyrylcholinesterase susceptibility ISO DNA:polymorphism: :p.A539T (human) RGD PMID:17852836 RGD:2306777 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
G Brinp3 BMP/retinoic acid inducible neural specific 3 ISO DNA:SNP: :rs12732361(human), associated with male. RGD PMID:27461004 RGD:14398490 NCBI chr13:63,526,486...63,959,390
Ensembl chr13:63,526,486...63,959,332
JBrowse link
G Btnl2 butyrophilin-like 2 susceptibility ISO associated with Mucocutaneous Lymph Node Syndrome; DNA:SNP: :rs 2395158(human) RGD PMID:19882345 RGD:9685030 NCBI chr20:4,140,184...4,156,365
Ensembl chr20:4,141,878...4,154,978
JBrowse link
G Cbs cystathionine beta synthase ISO CBS variant c.844ins68 RGD PMID:12855221 RGD:1600626 NCBI chr20:10,361,987...10,386,663
Ensembl chr20:10,361,988...10,386,751
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 IEP
ISO
protein:increased expression:myocardium (rat)
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Coronary artery disease, modifier of
protein:increased expression:serum (human)
CTD
ClinVar
PMID:11500196 PMID:15466648 PMID:16352737 PMID:16596675 PMID:16934270 PMID:18940815, PMID:16297799, PMID:9537339 RGD:8549513, RGD:8549577 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl26 C-C motif chemokine ligand 26 susceptibility ISO protein:decreased expression:plasma (human) RGD PMID:16620281 RGD:11081161 NCBI chr12:24,157,182...24,161,870
Ensembl chr12:24,158,766...24,161,869
JBrowse link
G Ccr1 C-C motif chemokine receptor 1 ISO RGD PMID:12742282 RGD:5508477 NCBI chr 8:132,996,646...133,002,201
Ensembl chr 8:132,996,649...133,002,201
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 ISO RGD PMID:12426226 RGD:1581178
G Ccr5 C-C motif chemokine receptor 5 IEP mRNA:increased expression:heart (rat) RGD PMID:17449418 RGD:4890438 NCBI chr 8:133,192,398...133,215,599
Ensembl chr 8:133,197,032...133,215,614
JBrowse link
G Cd14 CD14 molecule no_association ISO DNA:SNP:promoter RGD PMID:18157711 RGD:2314154 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153
JBrowse link
G Cd40lg CD40 ligand ISO
IEP
protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
associated with Mucocutaneous Lymph Node Syndrome;DNA:SNP: :rs4810485 (human)
protein:increased expression:coronary artery, serum
associated with Kidney Failure, Chronic
CTD PMID:16368305, PMID:17635572, PMID:22645426, PMID:23819214, PMID:16494885 RGD:2314209, RGD:8547776, RGD:7248750, RGD:7248436 NCBI chr  X:159,703,703...159,714,886
Ensembl chr  X:159,703,578...159,716,562
JBrowse link
G Cdh5 cadherin 5 ISO RGD PMID:14695457 RGD:1598391 NCBI chr19:1,025,122...1,074,333
Ensembl chr19:1,023,683...1,074,365
JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B ISO CTD Direct Evidence: marker/mechanism CTD PMID:23104008 NCBI chr 5:107,834,353...107,857,428
Ensembl chr 5:107,845,951...107,858,104
JBrowse link
G Cela2a chymotrypsin like elastase 2A ISO ClinVar Annotator: match by term: Coronary artery disease ClinVar PMID:31358993 NCBI chr 5:160,374,031...160,383,782
Ensembl chr 5:160,374,031...160,383,782
JBrowse link
G Chi3l1 chitinase 3 like 1 ISO protein:increased secretion:serum (human) RGD PMID:17627189 RGD:4892665 NCBI chr13:51,022,844...51,030,797
Ensembl chr13:51,022,681...51,030,802
JBrowse link
G Clcn6 chloride voltage-gated channel 6 susceptibility ISO DNA:SNP: :rs3737964(human) RGD PMID:26740945 RGD:14696742 NCBI chr 5:164,811,815...164,844,554
Ensembl chr 5:164,811,816...164,844,586
JBrowse link
G Clu clusterin ISO associated with Mucocutaneous Lymph Node Syndrome;protein:decreased expression:plasma RGD PMID:20711835 RGD:9068393 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
JBrowse link
G Crp C-reactive protein ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
CTD PMID:24868163, PMID:19615354 RGD:2313344 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Cst3 cystatin C ISO protein:increased expression:serum (human) RGD PMID:17983622 RGD:2314352 NCBI chr 3:143,219,671...143,223,544
Ensembl chr 3:143,219,686...143,223,615
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 ISS OMIM:300464 | OMIM:607339 | OMIM:608316 | OMIM:608318 | OMIM:608320 | OMIM:608901 | OMIM:610938 | OMIM:610947 | OMIM:611139 | OMIM:612030 | OMIM:614293 | OMIM:614466 MouseDO NCBI chr 8:128,740,756...128,754,514
Ensembl chr 8:128,740,756...128,754,514
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Cyba cytochrome b-245 alpha chain ISO RGD
GAD
PMID:14709372, PMID:15118671 RGD:1578443, RGD:1331525 NCBI chr19:55,249,634...55,257,824
Ensembl chr19:55,249,616...55,257,876
JBrowse link
G Ddah2 dimethylarginine dimethylaminohydrolase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17267746 NCBI chr20:5,049,260...5,052,573
Ensembl chr20:5,049,496...5,052,585
JBrowse link
G Dsp desmoplakin ISO ClinVar Annotator: match by term: Coronary artery disease ClinVar PMID:25741868 PMID:28492532 PMID:30311386 NCBI chr17:27,286,811...27,334,453
Ensembl chr17:27,286,796...27,334,379
JBrowse link
G Ece1 endothelin converting enzyme 1 ISO protein:increased expression:smooth muscle cell,macrophage RGD PMID:10973835, PMID:8994440 RGD:1580909, RGD:7244168 NCBI chr 5:156,215,469...156,318,652
Ensembl chr 5:156,215,417...156,318,671
JBrowse link
G Edn1 endothelin 1 treatment
severity
ISO
IMP
protein:increased expression:atherosclerotic lesions (human)
associated with Hypertension;DNA:missense mutation:cds:p.L198N (human)
RGD PMID:7968078, PMID:11927217, PMID:18923236 RGD:4144886, RGD:8662294, RGD:8661705 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Eng endoglin severity ISO protein:increased expression:plasma (human) RGD PMID:21667051 RGD:7248776 NCBI chr 3:11,679,530...11,717,486
Ensembl chr 3:11,679,530...11,717,485
JBrowse link
G Ephx2 epoxide hydrolase 2 ISO RGD PMID:14732757 RGD:1580982 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
G Epo erythropoietin ISO CTD Direct Evidence: therapeutic CTD PMID:25245553 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit susceptibility ISO DNA:SNP: :rs13181(human) RGD PMID:27566080 RGD:12880440 NCBI chr 1:80,293,574...80,307,334
Ensembl chr 1:80,293,566...80,307,344
JBrowse link
G Esr1 estrogen receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9396482 PMID:20559769, PMID:16159931 RGD:1580335 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20559769, PMID:16099331 RGD:1581014 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G F2 coagulation factor II treatment ISO RGD PMID:14961168 RGD:10449426 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031
JBrowse link
G F7 coagulation factor VII ISO associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:increased activity:plasma (human)
DNA:polymorphisms:cds:R353Q (human)
RGD PMID:10599031, PMID:8522401, PMID:11334615 RGD:2312400, RGD:2312408, RGD:2312397 NCBI chr16:81,824,610...81,834,923
Ensembl chr16:81,824,111...81,834,945
JBrowse link
G Fabp2 fatty acid binding protein 2 ISO associated with Diabetes Mellitus, Type 2 (MeSH:D003924) RGD PMID:15059615 RGD:1626412 NCBI chr 2:227,080,912...227,083,654
Ensembl chr 2:227,080,924...227,083,501
JBrowse link
G Fcgr2a Fc fragment of IgG receptor IIa ISO DNA:polymorphism: :p.H131R (human) RGD PMID:20973705 RGD:5147917 NCBI chr13:91,146,878...91,163,691
Ensembl chr13:91,168,973...91,198,036
Ensembl chr13:91,168,973...91,198,036
JBrowse link
G Fcgr3a Fc fragment of IgG receptor IIIa susceptibility ISO DNA:SNP:exon:p.F158V (rs396991)(human) RGD PMID:15910853 RGD:5508464 NCBI chr13:89,385,775...89,396,047
Ensembl chr13:89,385,859...89,396,051
JBrowse link
G Fgb fibrinogen beta chain ISO RGD PMID:8565160 RGD:1580382 NCBI chr 2:182,028,044...182,035,026
Ensembl chr 2:182,027,115...182,038,178
JBrowse link
G Fgf2 fibroblast growth factor 2 ISO associated with Diabetes Mellitus RGD PMID:14585103 RGD:2315879 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Gck glucokinase susceptibility ISO DNA:SNP:promoter:-30G>A (human) RGD PMID:15173029 RGD:2301876 NCBI chr14:86,149,146...86,191,589
Ensembl chr14:86,148,928...86,190,659
JBrowse link
G Gdf15 growth differentiation factor 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20855664 NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978
JBrowse link
G Gja4 gap junction protein, alpha 4 ISO RGD PMID:15059615 RGD:1626412 NCBI chr 5:145,374,688...145,377,221
Ensembl chr 5:145,374,690...145,377,221
JBrowse link
G Gnb3 G protein subunit beta 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16141801 NCBI chr 4:157,352,558...157,359,237
Ensembl chr 4:157,352,372...157,358,262
JBrowse link
G Gpx1 glutathione peroxidase 1 ISO cardiovascular complications in type 2 diabetics
DNA:repeat:exon
RGD PMID:16338763, PMID:12655278 RGD:1600708, RGD:1600677 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gsr glutathione-disulfide reductase ISO cardiovascular complications in type 2 diabetics RGD PMID:16338763 RGD:1600708 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gstm1 glutathione S-transferase mu 1 susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent
DNA:deletion
RGD PMID:19102712, PMID:16620396 RGD:2306625, RGD:2306633 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstt1 glutathione S-transferase theta 1 susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent
DNA:deletion
RGD PMID:19102712, PMID:16620396 RGD:2306625, RGD:2306633 NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526
JBrowse link
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22751097 NCBI chr 2:181,045,694...181,103,321
Ensembl chr 2:181,045,703...181,102,918
JBrowse link
G Hectd4 HECT domain E3 ubiquitin protein ligase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22751097 NCBI chr12:40,712,078...40,860,930
Ensembl chr12:40,713,841...40,822,159
JBrowse link
G Hfe homeostatic iron regulator no_association ISO RGD PMID:12746412 RGD:1582673 NCBI chr17:43,661,276...43,669,327
Ensembl chr17:43,661,222...43,669,985
JBrowse link
G Hgf hepatocyte growth factor ISO RGD PMID:11669408 RGD:8548610 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Hhipl1 HHIP-like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr 6:132,218,583...132,242,852
Ensembl chr 6:132,219,088...132,240,356
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase ISO RGD PMID:12742282 RGD:5508477 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hmox1 heme oxygenase 1 no_association
susceptibility
ISO DNA:repeat:promoter
CTD Direct Evidence: marker/mechanism
CTD PMID:12136229, PMID:14691581, PMID:12377749, PMID:12136229 RGD:1580470, RGD:1580454, RGD:1598401 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hp haptoglobin ISO protein:increased expression:serum RGD PMID:884791 RGD:1626363 NCBI chr19:42,096,255...42,100,805
Ensembl chr19:42,097,995...42,100,804
JBrowse link
G Hs3st1 heparan sulfate-glucosamine 3-sulfotransferase 1 ISO ClinVar Annotator: match by term: Coronary artery disease ClinVar PMID:15266341 PMID:15965027 PMID:16024819 PMID:16410828 PMID:17179217 PMID:17558387 PMID:17568005 PMID:19122651 PMID:19303047 PMID:19858363 PMID:21152010 PMID:22090374 PMID:28126521 NCBI chr14:75,880,410...75,881,346
Ensembl chr14:75,852,060...75,882,693
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 severity ISO RGD PMID:11222468 RGD:1624218 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
G Il10 interleukin 10 no_association
susceptibility
ISO DNA:SNPs:promoter:-592C>A (rs1800872), -819C>T (rs1800871) (human)
DNA:SNP:promoter:-1082A>G (rs1800896) (human)
RGD PMID:16460885, PMID:29525679, PMID:29525679 RGD:1598621, RGD:14975129, RGD:14975129 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il15 interleukin 15 ISO associated with Hypertension;protein:increased expression:serum RGD PMID:16109314 RGD:1626610 NCBI chr19:23,542,606...23,624,366
Ensembl chr19:23,542,889...23,554,594
JBrowse link
G Il1b interleukin 1 beta ISO mRNA:increased expression:peripheral blood (human) RGD PMID:22780915 RGD:7175093 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 severity ISO DNA:polymorphisms: :-27307T>A, -27614C>A (human) RGD PMID:20602249 RGD:5144241 NCBI chr 9:47,133,483...47,184,316
Ensembl chr 9:47,134,034...47,182,170
JBrowse link
G Il6 interleukin 6 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:increased expression:extracellular space (human) RGD PMID:19368923 RGD:2307251 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20524934 NCBI chr  X:156,716,469...156,726,367
Ensembl chr  X:156,716,604...156,725,977
JBrowse link
G Irs1 insulin receptor substrate 1 ISO DNA:polymorphism:exon:G972R
CTD Direct Evidence: marker/mechanism
CTD PMID:10591678, PMID:10591678 RGD:1624974 NCBI chr 9:88,033,668...88,086,488
Ensembl chr 9:88,033,668...88,086,488
JBrowse link
G Itga2 integrin subunit alpha 2 no_association ISO RGD PMID:15227729 RGD:1582294 NCBI chr 2:46,996,904...47,097,011
Ensembl chr 2:47,000,323...47,096,961
JBrowse link
G Jcad junctional cadherin 5 associated ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378988 NCBI chr17:55,667,754...55,709,738
Ensembl chr17:55,670,331...55,709,740
JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 ISS OMIM:300464 | OMIM:607339 | OMIM:608316 | OMIM:608318 | OMIM:608320 | OMIM:608901 | OMIM:610938 | OMIM:610947 | OMIM:611139 | OMIM:612030 | OMIM:614293 | OMIM:614466 MouseDO NCBI chr 4:176,783,287...176,789,143
Ensembl chr 4:176,782,498...176,789,304
JBrowse link
G Khdc3 KH domain containing 3, subcortical maternal complex member ISS OMIM:300464 | OMIM:607339 | OMIM:608316 | OMIM:608318 | OMIM:608320 | OMIM:608901 | OMIM:610938 | OMIM:610947 | OMIM:611139 | OMIM:612030 | OMIM:614293 | OMIM:614466 MouseDO NCBI chr 8:79,781,941...79,783,845
Ensembl chr 8:79,781,983...79,783,592
JBrowse link
G Kl Klotho ISO CTD Direct Evidence: marker/mechanism
DNA:SNP:promoter: -G395>A (human)
CTD PMID:12669274, PMID:16979405, PMID:16579981 RGD:1581721, RGD:1581723 NCBI chr12:942,974...987,206
Ensembl chr12:943,006...987,551
JBrowse link
G Ldlr low density lipoprotein receptor no_association ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 PMID:27135400, PMID:16459141 RGD:1581823 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903
JBrowse link
G Lepr leptin receptor susceptibility ISO DNA:SNP:cds:p.Q223R(human) RGD PMID:27257426 RGD:21079462 NCBI chr 5:120,503,475...120,682,281
Ensembl chr 5:120,564,645...120,682,221
JBrowse link
G Lipa lipase A, lysosomal acid type ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378988 NCBI chr 1:252,816,536...252,959,348
Ensembl chr 1:252,816,527...252,849,904
JBrowse link
G Lipc lipase C, hepatic type no_association ISO associated with Diabetes Mellitus, Insulin-Dependent; DNA:transition:promoter:-480C>T (human) RGD
GAD
PMID:11916946, PMID:15118671, PMID:12689525, PMID:15099346 RGD:2308839, RGD:1331525, RGD:1600664, RGD:1600663 NCBI chr 8:77,272,582...77,398,485
Ensembl chr 8:77,272,570...77,398,248
JBrowse link
G Lipg lipase G, endothelial type ISO RGD PMID:16354105 RGD:1580865 NCBI chr18:70,903,528...70,924,434
Ensembl chr18:70,901,710...70,924,708
JBrowse link
G Lmod1 leiomodin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28530674 NCBI chr13:52,147,099...52,189,835
Ensembl chr13:52,147,555...52,190,228
JBrowse link
G LOC102551309 uncharacterized LOC102551309 ISO DNA:SNP: :rs56001051(human) RGD PMID:31175347 RGD:14696712 NCBI chr 5:164,875,558...164,885,606
Ensembl chr 5:164,874,832...164,883,933
JBrowse link
G Lox lysyl oxidase IDA RGD PMID:12393934 RGD:1581886 NCBI chr18:47,500,320...47,577,819
Ensembl chr18:47,500,330...47,577,819
JBrowse link
G Lpl lipoprotein lipase ISO RGD PMID:8641022 RGD:1580537 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link
G Lrp6 LDL receptor related protein 6 ISS OMIM:300464 | OMIM:607339 | OMIM:608316 | OMIM:608318 | OMIM:608320 | OMIM:608901 | OMIM:610938 | OMIM:610947 | OMIM:611139 | OMIM:612030 | OMIM:614293 | OMIM:614466 MouseDO NCBI chr 4:168,194,054...168,323,962
Ensembl chr 4:168,194,927...168,323,751
JBrowse link
G Lrp8 LDL receptor related protein 8 no_association
onset
ISO DNA:missense mutation:cds:p.R952Q (human) RGD PMID:18592168, PMID:17847002 RGD:2306125, RGD:2306124 NCBI chr 5:127,404,348...127,476,636
Ensembl chr 5:127,404,450...127,476,641
JBrowse link
G Lta lymphotoxin alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:15266304, PMID:15973460 RGD:1580414 NCBI chr20:4,851,889...4,854,677
Ensembl chr20:4,852,496...4,854,677
JBrowse link
G Lum lumican ISO RGD PMID:11890723 RGD:1582121 NCBI chr 7:38,820,058...38,826,862
Ensembl chr 7:38,819,771...38,826,862
JBrowse link
G Mef2a myocyte enhancer factor 2a ISO
ISS
OMIM:300464 | OMIM:607339 | OMIM:608316 | OMIM:608318 | OMIM:608320 | OMIM:608901 | OMIM:610938 | OMIM:610947 | OMIM:611139 | OMIM:612030 | OMIM:614293 | OMIM:614466 MouseDO PMID:15811259 RGD:1580548 NCBI chr 1:128,207,715...128,341,681
Ensembl chr 1:128,209,971...128,341,263
JBrowse link
G Mia3 MIA SH3 domain ER export factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr13:101,727,434...101,770,127
Ensembl chr13:101,727,935...101,761,541
JBrowse link
G Mir146a microRNA 146a ISO CTD Direct Evidence: marker/mechanism
miRNA:increased expression:peripheral blood mononuclear cell, plasma
CTD PMID:20524934, PMID:31866771 RGD:21081515 NCBI chr10:28,962,476...28,962,570
Ensembl chr10:28,962,476...28,962,570
JBrowse link
G Mir146b microRNA 146b ISO CTD Direct Evidence: marker/mechanism CTD PMID:20524934 NCBI chr 1:266,089,488...266,089,575
Ensembl chr 1:266,089,488...266,089,575
JBrowse link
G Mir155 microRNA 155 ISO miRNA:decreased expression:peripheral blood mononuclear cell, plasma RGD PMID:31866771 RGD:21081515 NCBI chr11:24,176,603...24,176,667
Ensembl chr11:24,176,603...24,176,667
JBrowse link
G Mir21 microRNA 21 ISO miRNA:increased expression:peripheral blood mononuclear cell, plasma RGD PMID:31866771 RGD:21081515 NCBI chr10:73,902,210...73,902,301
Ensembl chr10:73,902,210...73,902,301
JBrowse link
G Mir223 microRNA 223 treatment ISO RGD PMID:25350775 RGD:11076984 NCBI chr  X:65,367,812...65,367,921
Ensembl chr  X:65,367,812...65,367,921
JBrowse link
G Mmp1 matrix metallopeptidase 1 severity ISO DNA:insertion, haplotype:promoter:g.-1607insG rs799750 (human) RGD PMID:15619398, PMID:17893005 RGD:1582527, RGD:7207049 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mmp12 matrix metallopeptidase 12 susceptibility ISO RGD PMID:10807873 RGD:1582366 NCBI chr 8:5,594,717...5,616,494
Ensembl chr 8:5,606,592...5,616,493
JBrowse link
G Mmp3 matrix metallopeptidase 3 ISO DNA:insertion, haplotype:promoter:g.-1613insA rs3025058 (human)
CTD Direct Evidence: marker/mechanism
associated with Mucocutaneous Lymph Node Syndrome
CTD PMID:8662692, PMID:17893005, PMID:16100452 RGD:7207049, RGD:8693322 NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579
JBrowse link
G Mmp9 matrix metallopeptidase 9 susceptibility
treatment
ISO
IEP
RGD PMID:15191941, PMID:26261622 RGD:1582644, RGD:11344965 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mras muscle RAS oncogene homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr 8:107,629,028...107,656,851
Ensembl chr 8:107,629,028...107,681,512
JBrowse link
G Mrps6 mitochondrial ribosomal protein S6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr11:32,208,246...32,263,999
Ensembl chr11:32,211,115...32,263,899
JBrowse link
G Mthfr methylenetetrahydrofolate reductase no_association
susceptibility
ISO DNA:transition:cds:g.677C>T (human) RGD PMID:15648053, PMID:12387655 RGD:1580579, RGD:6893453 NCBI chr 5:164,844,642...164,864,360
Ensembl chr 5:164,845,925...164,860,910
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase ISO RGD PMID:17283255 RGD:1642340 NCBI chr 6:52,122,085...52,156,473
Ensembl chr 6:52,122,085...52,156,472
JBrowse link
G Nat2 N-acetyltransferase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21572414 NCBI chr16:23,960,709...23,991,570
Ensembl chr16:23,961,067...23,991,570
JBrowse link
G Ngf nerve growth factor ISO RGD PMID:11935372 RGD:1580935 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
JBrowse link
G Ngfr nerve growth factor receptor ISO RGD PMID:11935372 RGD:1580935 NCBI chr10:83,389,828...83,408,061
Ensembl chr10:83,389,847...83,408,061
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 ISO DNA:polymorphisms: :p.G908R, 3020_3021insC (human) RGD PMID:21565239 RGD:5508725 NCBI chr19:19,342,061...19,389,366
Ensembl chr19:19,332,594...19,377,492
JBrowse link
G Nos2 nitric oxide synthase 2 ISO associated with Mucocutaneous Lymph Node Syndrome; protein:increased expression:neutrophil, monocyte RGD PMID:14764920 RGD:1580941 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nos3 nitric oxide synthase 3 susceptibility ISO DNA:duplication:intron:IVS4?-?+27 (human)
CTD Direct Evidence: marker/mechanism
DNA:snp:promoter:g.-786T>C (human)
DNA:snp:cds:c.894G>T (human)
CTD PMID:10510054 PMID:14989558 PMID:17267746 PMID:19696404, PMID:8564837, PMID:19761682, PMID:16284093 RGD:7421529, RGD:7771578, RGD:7771567 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Nppa natriuretic peptide A ISO DNA:snp:cds:c.2238T>C (human)
associated with Diabetes Mellitus, Type 2;DNA:SNP:exon: 2238T>C,rs5065 (human)
RGD PMID:12514664, PMID:22170009 RGD:1579982, RGD:7247716 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705
JBrowse link
G Nppb natriuretic peptide B ISO CTD Direct Evidence: marker/mechanism CTD PMID:18022110 NCBI chr 5:164,796,176...164,797,538
Ensembl chr 5:164,796,185...164,797,531
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 ISO DNA:missense mutation:cds:p.N363S (human) RGD PMID:12623935 RGD:1580790 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 severity ISO DNA:snp:3' utr:T>C (human)
DNA:missense mutation:cds:p.K167N (human)
RGD PMID:12810610, PMID:15562935 RGD:1580995, RGD:1580994 NCBI chr 4:163,239,853...163,261,937
Ensembl chr 4:163,239,849...163,261,958
JBrowse link
G Pappa1 pappalysin 1 severity ISO CTD Direct Evidence: marker/mechanism CTD PMID:11586954, PMID:16055491 RGD:1642327 NCBI chr 5:80,919,932...81,153,904
Ensembl chr 5:80,920,568...81,150,940
JBrowse link
G Parl presenilin associated, rhomboid-like susceptibility ISO DNA:missense mutation:cds:p.L262V (human) RGD PMID:18758826 RGD:12902623 NCBI chr11:84,517,368...84,544,463
Ensembl chr11:84,517,368...84,544,462
JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 PMID:27135400 NCBI chr 5:126,031,368...126,053,726
Ensembl chr 5:126,031,368...126,053,726
JBrowse link
G Pdgfd platelet derived growth factor D ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378988 NCBI chr 8:4,441,010...4,666,754
Ensembl chr 8:4,440,876...4,669,014
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 no_association ISO DNA:missense mutations:cds:p.N536S, p.G670R (human)
CTD Direct Evidence: marker/mechanism
DNA:missense mutation:cds:p.L125V (human)
DNA:polymorphism:5' utr:g.53G>A (human)
CTD PMID:28530674, PMID:11795274, PMID:10780329, PMID:12732396 RGD:2311656, RGD:6771225, RGD:1581010 NCBI chr10:94,850,971...94,913,202 JBrowse link
G Phactr1 phosphatase and actin regulator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 PMID:22751097 PMID:26098115 NCBI chr17:23,245,423...23,761,207 JBrowse link
G Pla2g7 phospholipase A2 group VII disease_progression
susceptibility
ISO DNA:polymorphism: :p.A379V (human) RGD PMID:17070179, PMID:15115767 RGD:6482777, RGD:6482781 NCBI chr 9:19,935,754...19,978,013
Ensembl chr 9:19,935,768...19,978,013
JBrowse link
G Plpp3 phospholipid phosphatase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr 5:124,690,214...124,765,499
Ensembl chr 5:124,690,214...124,765,498
JBrowse link
G Pnpla3 patatin-like phospholipase domain containing 3 ISO associated with type 2 diabetes mellitus;DNA:SNP: :rs738409 (p.I148M) (human) RGD PMID:31377187 RGD:14981594 NCBI chr 7:125,034,760...125,056,165
Ensembl chr 7:125,034,764...125,055,976
JBrowse link
G Pon1 paraoxonase 1 susceptibility ISO DNA:missense mutation:cds:p.Q192R (human)
CTD Direct Evidence: marker/mechanism|therapeutic
ClinVar Annotator: match by term: Coronary artery spasm 2, susceptibility to
protein:increased activity:serum (human)
CTD
ClinVar
PMID:7916578 PMID:8098250 PMID:8675673 PMID:8770857 PMID:9215303 PMID:9385372 PMID:9443884 PMID:11238489 PMID:11810302 PMID:11888590 PMID:12082503 PMID:15241482 PMID:21170047 PMID:21629682, PMID:10729395, PMID:15785307, PMID:11917194 RGD:1580196, RGD:8547681, RGD:1580203 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Pon2 paraoxonase 2 severity ISO DNA:missense mutation:cds:p.C311S (human) RGD PMID:12454802 RGD:1580217 NCBI chr 4:30,344,705...30,380,119
Ensembl chr 4:30,344,709...30,380,119
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha susceptibility ISO DNA:snp:intron: (human) RGD PMID:16043164 RGD:1580228 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma ISO protein:decreased expression:carotid artery, macrophage, smooth muscle cell (human) RGD PMID:21709632 RGD:8552814 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Prkag2 protein kinase AMP-activated non-catalytic subunit gamma 2 ISO ClinVar Annotator: match by term: Coronary artery disease ClinVar PMID:25741868 PMID:28492532 PMID:30311386 NCBI chr 4:6,559,153...6,799,888
Ensembl chr 4:6,559,545...6,799,632
JBrowse link
G Procr protein C receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:28530674 NCBI chr 3:151,285,321...151,289,581
Ensembl chr 3:151,285,249...151,289,595
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14642682 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Pth parathyroid hormone ISO protein:increased expression:serum (human) RGD PMID:23460043 RGD:7242420 NCBI chr 1:178,215,829...178,218,761
Ensembl chr 1:178,215,829...178,218,761
JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 ISO DNA: snp: cds: rs2476601 RGD PMID:21846984 RGD:6484553 NCBI chr 2:206,342,066...206,390,348
Ensembl chr 2:206,342,066...206,390,348
JBrowse link
G Rnf213 ring finger protein 213 ISO ClinVar Annotator: match by term: Coronary artery disease ClinVar PMID:25741868 PMID:30311386 NCBI chr10:108,527,351...108,626,372
Ensembl chr10:108,527,740...108,624,688
JBrowse link
G Sele selectin E susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:mutation: :p.S128R (human) RGD PMID:17578587 RGD:2313596 NCBI chr13:82,355,234...82,365,323
Ensembl chr13:82,355,471...82,365,341
JBrowse link
G Selp selectin P ISO ClinVar Annotator: match by term: Premature coronary artery disease ClinVar NCBI chr13:82,428,914...82,464,629
Ensembl chr13:82,429,063...82,464,628
JBrowse link
G Serpina1 serpin family A member 1 ISO protein:increased expression:serum RGD PMID:7832094 RGD:1643149 NCBI chr 6:127,610,241...127,632,265
Ensembl chr 6:127,610,243...127,632,265
JBrowse link
G Serpine1 serpin family E member 1 susceptibility ISO DNA:insertion:promoter: (human) RGD PMID:9484978 RGD:1580190 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Serpinf2 serpin family F member 2 ISO RGD PMID:9184412 RGD:1625532 NCBI chr10:62,264,247...62,272,353
Ensembl chr10:62,264,788...62,273,119
JBrowse link
G Sh2b3 SH2B adaptor protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr12:40,261,990...40,265,757
Ensembl chr12:40,244,081...40,265,757
JBrowse link
G Soat2 sterol O-acyltransferase 2 susceptibility ISO DNA:polymorphisms: :p.E41G, p.T734I, IVS4-57_-58ins48bp (human) RGD PMID:16195894 RGD:1601112 NCBI chr 7:143,754,892...143,767,989
Ensembl chr 7:143,754,892...143,767,989
JBrowse link
G Sod1 superoxide dismutase 1 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent RGD PMID:16338763 RGD:1600708 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod3 superoxide dismutase 3 ISO RGD PMID:10811593 RGD:1580853 NCBI chr14:60,958,583...60,971,143
Ensembl chr14:60,958,592...60,964,324
JBrowse link
G Sort1 sortilin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr 2:211,078,092...211,156,312
Ensembl chr 2:211,078,334...211,156,312
JBrowse link
G Spp1 secreted phosphoprotein 1 ISO In type 2 diabetic patients RGD PMID:21034455 RGD:6903271 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member ISO GAD PMID:15118671 RGD:1331525 NCBI chr20:3,979,302...3,989,669
Ensembl chr20:3,979,035...3,989,669
JBrowse link
G Tcf21 transcription factor 21 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 PMID:22751097 NCBI chr 1:23,906,717...23,909,576
Ensembl chr 1:23,906,717...23,909,566
JBrowse link
G Tek TEK receptor tyrosine kinase ISO protein:increased expression:plasma RGD PMID:12814387 RGD:1601489 NCBI chr 5:113,725,717...113,852,799
Ensembl chr 5:113,725,717...113,852,799
JBrowse link
G Tert telomerase reverse transcriptase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16890917 NCBI chr 1:32,250,876...32,275,330
Ensembl chr 1:32,251,714...32,272,476
JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO GAD PMID:15118671 RGD:1331525 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Thbd thrombomodulin severity ISO RGD PMID:17012137 RGD:1601638 NCBI chr 3:142,748,673...142,752,325
Ensembl chr 3:142,748,674...142,752,325
JBrowse link
G Tlr4 toll-like receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20524934, PMID:15632890 RGD:1580736 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tnf tumor necrosis factor ISO RGD PMID:15059615 RGD:1626412 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B ISO protein:increased expression:serum RGD PMID:15926884 RGD:1620893 NCBI chr 7:93,798,580...93,826,586
Ensembl chr 7:93,798,545...93,826,665
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A severity ISO RGD PMID:19845893 RGD:5131425 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tnni3 troponin I3, cardiac type ISO RGD PMID:12221049 RGD:1580780 NCBI chr 1:72,882,806...72,886,490
Ensembl chr 1:72,882,806...72,886,488
JBrowse link
G Tp53 tumor protein p53 ISO DNA:misssense mutation: :p.R72P (rs1042522) (human) RGD PMID:29482350 RGD:14995930 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Traf6 TNF receptor associated factor 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20524934 NCBI chr 3:91,252,829...91,271,607
Ensembl chr 3:91,252,829...91,271,607
JBrowse link
G Trib1 tribbles pseudokinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24097064 NCBI chr 7:99,954,492...99,961,026
Ensembl chr 7:99,954,492...99,961,026
JBrowse link
G Ttn titin ISO RGD PMID:12221049 RGD:1580780 NCBI chr 3:63,565,160...63,837,815 JBrowse link
G Vdr vitamin D receptor severity ISO DNA:SNP (human) RGD PMID:9761785 RGD:4889864 NCBI chr 7:139,344,452...139,394,138
Ensembl chr 7:139,342,063...139,394,166
JBrowse link
G Vegfa vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:14668888 PMID:15937083, PMID:15754021 RGD:1580569 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Vim vimentin ISO protein:increased expression:monocyte RGD PMID:21938407 RGD:6480617 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
JBrowse link
G Vtn vitronectin ISO RGD PMID:15678274 RGD:1580816 NCBI chr10:65,767,960...65,771,040
Ensembl chr10:65,767,053...65,771,038
JBrowse link
G Wdr12 WD repeat domain 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr 9:66,851,499...66,878,534
Ensembl chr 9:66,851,940...66,877,972
JBrowse link
G Wrn WRN RecQ like helicase ISO RGD PMID:11186893 RGD:1580824 NCBI chr16:62,483,773...62,619,018
Ensembl chr16:62,483,761...62,615,375
JBrowse link
G Zc3hc1 zinc finger, C3HC-type containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr 4:57,684,678...57,706,613
Ensembl chr 4:57,684,678...57,706,613
JBrowse link
Coronary Artery Disease, Autosomal Dominant 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mef2a myocyte enhancer factor 2a ISO ClinVar Annotator: match by term: Coronary artery disease/myocardial infarction
ClinVar Annotator: match by OMIM:608320
OMIM
ClinVar
PMID:14645853 PMID:15496429 PMID:15841183 NCBI chr 1:128,207,715...128,341,681
Ensembl chr 1:128,209,971...128,341,263
JBrowse link
Coronary Artery Disease, Autosomal Dominant 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrp6 LDL receptor related protein 6 ISO ClinVar Annotator: match by term: Coronary artery disease, autosomal dominant 2
ClinVar Annotator: match by OMIM:610947
OMIM
ClinVar
PMID:17332414 PMID:23703864 PMID:25741868 NCBI chr 4:168,194,054...168,323,962
Ensembl chr 4:168,194,927...168,323,751
JBrowse link
Coronary Artery Disease, Development of, in HIV term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl2 C-C motif chemokine ligand 2 ISO ClinVar Annotator: match by null ClinVar PMID:11500196 PMID:15466648 PMID:16352737 PMID:16596675 PMID:18940815 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
coronary artery vasospasm term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgap9 Rho GTPase activating protein 9 ISO ClinVar Annotator: match by term: Coronary artery spasm 3, susceptibility to
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
PMID:19911011 NCBI chr 7:70,612,650...70,620,900
Ensembl chr 7:70,612,103...70,620,890
JBrowse link
G Nos3 nitric oxide synthase 3 ISO ClinVar Annotator: match by term: Coronary artery spasm 1, susceptibility to
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
CTD
PMID:9737779 PMID:9894802 PMID:10359729 PMID:10475066 PMID:10510054 PMID:10514107 PMID:11026457 PMID:11354626 PMID:11394896 PMID:11745998 PMID:15007011 PMID:16059745 PMID:16813604 PMID:17165044 PMID:24033266 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Pon1 paraoxonase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11810302 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
Coronary Disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 ISO ClinVar Annotator: match by term: Coronary heart disease in familial hypercholesterolemia, protection against
ClinVar Annotator: match by term: Early-onset coronary artery disease
ClinVar PMID:11238261 PMID:12624133 PMID:16372134 PMID:16429166 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015
JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19060911 NCBI chr 6:7,935,771...7,961,207
Ensembl chr 6:7,935,771...7,961,207
JBrowse link
G Abo ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase ISO ClinVar Annotator: match by term: Three Vessel Coronary Disease ClinVar NCBI chr 3:4,374,679...4,394,374
Ensembl chr 3:4,374,602...4,394,428
JBrowse link
G Ace angiotensin I converting enzyme susceptibility ISO DNA:deletion:intron:IVS16+1464-1751del (human)
CTD Direct Evidence: marker/mechanism
CTD PMID:8170965, PMID:9488209 RGD:8142364 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Ace2 angiotensin I converting enzyme 2 susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism: :8790G>A (human) RGD PMID:18753062 RGD:2313798 NCBI chr  X:32,050,734...32,095,860
Ensembl chr  X:32,049,931...32,096,016
JBrowse link
G Ada adenosine deaminase ISO protein:increased expression:leukocyte RGD PMID:17259686 RGD:1624286 NCBI chr 3:160,115,840...160,139,947
Ensembl chr 3:160,115,842...160,139,947
JBrowse link
G Adamts13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 ISO protein:decreased activity:plasma (human)
ClinVar Annotator: match by term: Three Vessel Coronary Disease
ClinVar PMID:25741868, PMID:12670342 RGD:10449044 NCBI chr 3:5,519,921...5,558,390
Ensembl chr 3:5,519,990...5,558,166
JBrowse link
G Adamts7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 ISO ClinVar Annotator: match by term: Three Vessel Coronary Disease ClinVar NCBI chr 8:97,535,777...97,575,661
Ensembl chr 8:97,535,777...97,575,655
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing disease_progression ISO associated with Diabetes mellitus, Type2; RGD PMID:22207678, PMID:22019747 RGD:5686379, RGD:5686406 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Adrb2 adrenoceptor beta 2 susceptibility ISO DNA:polymorphism: :p.Q27E RGD PMID:12682000 RGD:1601128 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834
JBrowse link
G Adrb3 adrenoceptor beta 3 susceptibility ISO associated with Diabetes Mellitus, Type 2; DNA:missense mutation:cds:p.W64R rs4994(human) RGD
GAD
PMID:10421225, PMID:20536507, PMID:15118671 RGD:1559326, RGD:5684776, RGD:1331525 NCBI chr16:69,003,541...69,006,632
Ensembl chr16:69,003,868...69,006,632
JBrowse link
G Ager advanced glycosylation end product-specific receptor susceptibility ISO protein:decreased expression:plasma (human)
associated with Heart Failure; protein:increased expression:plasma (human)
RGD PMID:23396398, PMID:20685687 RGD:7243186, RGD:7244134 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Agtr1a angiotensin II receptor, type 1a susceptibility
no_association
ISO DNA:polymorphism:3' utr:1166A>C
DNA:polymorphism:3' utr:1166A>C (human)
RGD PMID:9456365, PMID:9857918 RGD:1601152, RGD:1566499 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077
JBrowse link
G Apoa4 apolipoprotein A4 susceptibility
no_association
ISO DNA:missense mutation:cds:p.T347S (human) RGD PMID:12676816, PMID:9013087 RGD:1578411, RGD:5685683 NCBI chr 8:50,536,983...50,539,371
Ensembl chr 8:50,537,009...50,539,376
JBrowse link
G Apob apolipoprotein B ISO CTD Direct Evidence: marker/mechanism CTD PMID:17658632 NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997
JBrowse link
G Apoc2 apolipoprotein C2 susceptibility ISO RGD PMID:7590197 RGD:1601205 NCBI chr 1:80,589,023...80,593,991
Ensembl chr 1:80,589,023...80,594,136
JBrowse link
G Apoc3 apolipoprotein C3 no_association
susceptibility
ISO DNA:polymorphism:promoter:-482C>T
ClinVar Annotator: match by term: Coronary heart disease
associated with Diabetes Mellitus, Non-Insulin-Dependent
ClinVar PMID:19074352 PMID:24941081 PMID:24941082 PMID:25962519 PMID:28406212, PMID:16321685, PMID:17654446 RGD:1601224, RGD:2306754 NCBI chr 8:50,529,318...50,531,498
Ensembl chr 8:50,529,318...50,531,498
JBrowse link
G Apoe apolipoprotein E onset ISO DNA:polymorphisms, haplotype:promoter, cds:g.-219G>T, p.C112R, p.R158C (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:10736278 PMID:11862316, PMID:11862316 RGD:1578479, RGD:1578479 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Ccdc92 coiled-coil domain containing 92 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28869590 NCBI chr12:37,210,735...37,237,848
Ensembl chr12:37,211,316...37,237,848
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 resistance ISO DNA:polymorphisms:multiple (human) RGD PMID:16055130 RGD:1581176 NCBI chr 8:133,192,398...133,215,599
Ensembl chr 8:133,197,032...133,215,614
JBrowse link
G Cd14 CD14 molecule ISO protein:increased expression:monocyte RGD PMID:10831941 RGD:2314175 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153
JBrowse link
G Cd36 CD36 molecule susceptibility ISO mRNA:increased expression:monocyte
CTD Direct Evidence: marker/mechanism
CTD
OMIM
PMID:18067591 RGD:6893507 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cd40lg CD40 ligand treatment IDA RGD PMID:23819214 RGD:7248750 NCBI chr  X:159,703,703...159,714,886
Ensembl chr  X:159,703,578...159,716,562
JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B ISO ClinVar Annotator: match by term: Three Vessel Coronary Disease ClinVar NCBI chr 5:107,834,353...107,857,428
Ensembl chr 5:107,845,951...107,858,104
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 susceptibility ISO DNA:polymorphism: :p.V249I (human)
CTD Direct Evidence: marker/mechanism
CTD
OMIM
PMID:11532900 RGD:4891901 NCBI chr 8:128,740,756...128,754,514
Ensembl chr 8:128,740,756...128,754,514
JBrowse link
G Cyba cytochrome b-245 alpha chain ISO RGD PMID:10488959 RGD:1580275 NCBI chr19:55,249,634...55,257,824
Ensembl chr19:55,249,616...55,257,876
JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 resistance ISO DNA:polymorphism:promoter:-50G>T (human) RGD PMID:17429317 RGD:1625377 NCBI chr 5:119,546,458...119,564,843
Ensembl chr 5:119,546,461...119,564,846
JBrowse link
G Dnah11 dynein, axonemal, heavy chain 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19060911 NCBI chr 6:145,784,893...146,099,212
Ensembl chr 6:145,785,275...146,099,053
JBrowse link
G Ephx2 epoxide hydrolase 2 ISO RGD PMID:16595607 RGD:1580981 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
G Esr2 estrogen receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17367797 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G F12 coagulation factor XII ISO protein:decreased activity:: RGD PMID:18021303 RGD:11041785 NCBI chr17:9,736,577...9,744,420
Ensembl chr17:9,736,577...9,744,420
JBrowse link
G F13a1 coagulation factor XIII A1 chain ISO RGD PMID:11391716 RGD:1581030 NCBI chr17:28,504,650...28,680,015
Ensembl chr17:28,504,623...28,680,362
JBrowse link
G Fgf2 fibroblast growth factor 2 ISO associated with Diabetes Mellitus RGD PMID:15451784 RGD:2315870 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 ISO mRNA, protein:increased expression:ventricle myocardium RGD PMID:16139132 RGD:2313728 NCBI chr12:9,033,993...9,205,886
Ensembl chr12:9,034,308...9,205,905
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:increased activity:serum RGD PMID:16772340 RGD:2315604 NCBI chr20:14,019,723...14,045,781
Ensembl chr20:14,019,723...14,025,068
JBrowse link
G Gp1ba glycoprotein Ib platelet subunit alpha ISO RGD PMID:14592833 RGD:1580433 NCBI chr10:57,260,680...57,263,546
Ensembl chr10:57,260,680...57,263,546
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase disease_progression ISO RGD PMID:15809366 RGD:5508474 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hmox1 heme oxygenase 1 ISO RGD PMID:15869055 RGD:1598404 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hnf1a HNF1 homeobox A ISO CTD Direct Evidence: marker/mechanism CTD PMID:28869590 NCBI chr12:47,407,811...47,433,342
Ensembl chr12:47,407,811...47,433,342
JBrowse link
G Hp haptoglobin severity ISO RGD PMID:16673012 RGD:1626344 NCBI chr19:42,096,255...42,100,805
Ensembl chr19:42,097,995...42,100,804
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A ISO DNA:SNPs: : -110A>C (rs1008438), 190G>C (rs1043618) (human) RGD PMID:19333379 RGD:7257652 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 ISO RGD PMID:12059985 RGD:1624217 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
G Igf1 insulin-like growth factor 1 ISO RGD PMID:15521962 RGD:1626121 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igfals insulin-like growth factor binding protein, acid labile subunit ISO RGD PMID:15521962 RGD:1626121 NCBI chr10:14,240,308...14,243,554
Ensembl chr10:14,240,219...14,243,597
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 ISO RGD PMID:15521962 RGD:1626121 NCBI chr14:87,457,647...87,465,374
Ensembl chr14:87,457,647...87,465,374
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 ISO RGD PMID:15521962 RGD:1626121 NCBI chr 9:80,154,230...80,166,813
Ensembl chr 9:80,150,211...80,167,033
JBrowse link
G Il18 interleukin 18 ISO ClinVar Annotator: match by term: Three Vessel Coronary Disease ClinVar NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il1b interleukin 1 beta ISO DNA:polymorphism RGD PMID:15379752 RGD:1626636 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Irs1 insulin receptor substrate 1 ISO ClinVar Annotator: match by term: Coronary artery disease, susceptibility to
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
PMID:1311924 PMID:7623569 PMID:8104271 PMID:8647950 PMID:10084586 PMID:10430617 PMID:10591678 PMID:10843189 PMID:12843189 PMID:14671192 PMID:14707024 PMID:15240653 PMID:28869590 NCBI chr 9:88,033,668...88,086,488
Ensembl chr 9:88,033,668...88,086,488
JBrowse link
G Itga2 integrin subunit alpha 2 no_association ISO RGD PMID:9684730 RGD:1582306 NCBI chr 2:46,996,904...47,097,011
Ensembl chr 2:47,000,323...47,096,961
JBrowse link
G Itgb3 integrin subunit beta 3 ISO DNA:polymorphism:exon RGD PMID:10583927 RGD:5128478 NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410
JBrowse link
G Kalrn kalirin, RhoGEF kinase ISO ClinVar Annotator: match by OMIM:608901
ClinVar Annotator: match by term: CORONARY ARTERY DISEASE, EARLY-ONSET
ClinVar PMID:17357071 PMID:25741868 NCBI chr11:69,484,293...70,025,682
Ensembl chr11:69,484,293...70,025,633
JBrowse link
G Kat2b lysine acetyltransferase 2B severity ISO DNA:snp:promoter:g.-2481G>C (human) RGD PMID:21062767 RGD:9590309 NCBI chr 9:4,440,982...4,492,949 JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 no_association ISO RGD PMID:12964027 RGD:1581699 NCBI chr 4:176,783,287...176,789,143
Ensembl chr 4:176,782,498...176,789,304
JBrowse link
G Kdr kinase insert domain receptor ISO mRNA, protein:increased expression:ventricle myocardium RGD PMID:16139132 RGD:2313728 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183
JBrowse link
G Ldlr low density lipoprotein receptor ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Three Vessel Coronary Disease
ClinVar Annotator: match by term: Early-onset coronary artery disease
CTD
ClinVar
PMID:9430375 PMID:9712531 PMID:10422804 PMID:11810272 PMID:11845603 PMID:17765246 PMID:19318025 PMID:20506408 PMID:21382890 PMID:21642693 PMID:23375686 PMID:24033266 PMID:25647241 PMID:25741868 PMID:28161202 PMID:28492532 PMID:28895539 PMID:29353225 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903
JBrowse link
G Lgals2 galectin 2 susceptibility ISO RGD PMID:17040205 RGD:1581853 NCBI chr 7:120,071,122...120,077,612
Ensembl chr 7:120,071,124...120,077,612
JBrowse link
G Lipc lipase C, hepatic type susceptibility ISO associated with Obesity and Diabetes; DNA:transition:promoter:-514C>T (human) RGD PMID:16570154 RGD:2308824 NCBI chr 8:77,272,582...77,398,485
Ensembl chr 8:77,272,570...77,398,248
JBrowse link
G Lpl lipoprotein lipase IEP
ISO
ClinVar Annotator: match by term: Coronary heart disease ClinVar PMID:8199176 PMID:8541837 PMID:8872057 PMID:10364086 PMID:10517255 PMID:21146168 PMID:24033266, PMID:27000070 RGD:13794381 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link
G Lrp1 LDL receptor related protein 1 susceptibility ISO RGD PMID:15121769 RGD:1581911 NCBI chr 7:70,846,313...70,927,028
Ensembl chr 7:70,846,344...70,926,903
JBrowse link
G Maco1 macoilin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19060911 NCBI chr 5:153,122,780...153,184,940
Ensembl chr 5:153,122,781...153,184,940
JBrowse link
G Mb myoglobin severity ISO RGD PMID:15976963 RGD:1582388 NCBI chr 7:118,101,633...118,108,864
Ensembl chr 7:118,101,634...118,108,864
JBrowse link
G Mgp matrix Gla protein susceptibility ISO RGD PMID:16973975 RGD:1582502 NCBI chr 4:170,856,783...170,860,105
Ensembl chr 4:170,856,751...170,860,225
JBrowse link
G Mif macrophage migration inhibitory factor IEP coronary occlusion; mRNA:increased expression:myocardium RGD PMID:20367970 RGD:4890973 NCBI chr20:13,715,219...13,732,980
Ensembl chr20:13,732,198...13,732,859
JBrowse link
G Mmp1 matrix metallopeptidase 1 susceptibility ISO DNA:insertion:promoter:g.-1607insG (human) RGD PMID:14499230 RGD:1582537 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mmp3 matrix metallopeptidase 3 susceptibility ISO CTD Direct Evidence: marker/mechanism OMIM
CTD
NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579
JBrowse link
G Mras muscle RAS oncogene homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:28869590 NCBI chr 8:107,629,028...107,656,851
Ensembl chr 8:107,629,028...107,681,512
JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16792904 NCBI chr 5:164,844,642...164,864,360
Ensembl chr 5:164,845,925...164,860,910
JBrowse link
G Mttp microsomal triglyceride transfer protein susceptibility ISO DNA:polymorphism:promoter:-493G>T RGD PMID:15136504 RGD:1625487 NCBI chr 2:243,366,181...243,407,608
Ensembl chr 2:243,366,181...243,407,608
JBrowse link
G Myh15 myosin, heavy chain 15 ISO DNA:snp:exon:EX28T>C rs3900940 (human) RGD PMID:18073581 RGD:2317145 NCBI chr11:54,205,771...54,344,662
Ensembl chr11:54,204,775...54,344,615
JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 susceptibility ISO DNA:missense mutation, nonsense mutations:cds:p.R46L, p.Y142X, p.C679X (human) RGD PMID:16554528 RGD:1581000 NCBI chr 5:126,031,368...126,053,726
Ensembl chr 5:126,031,368...126,053,726
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 ISO ClinVar Annotator: match by term: Three Vessel Coronary Disease ClinVar PMID:8532023 NCBI chr10:94,850,971...94,913,202 JBrowse link
G Pla2g7 phospholipase A2 group VII ISO CTD Direct Evidence: marker/mechanism CTD PMID:21356620, PMID:15699277 RGD:6482780 NCBI chr 9:19,935,754...19,978,013
Ensembl chr 9:19,935,768...19,978,013
JBrowse link
G Plau plasminogen activator, urokinase ISO CTD Direct Evidence: therapeutic CTD PMID:1730212 PMID:9181759 NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819
JBrowse link
G Pltp phospholipid transfer protein susceptibility ISO protein:increased expression:serum (human) RGD PMID:14695459 RGD:1581038 NCBI chr 3:161,304,469...161,322,289
Ensembl chr 3:161,304,469...161,322,289
JBrowse link
G Pon1 paraoxonase 1 severity
no_association
ISO protein:decreased expression:serum
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Coronary artery disease, susceptibility to
DNA:missense mutation:cds:p.Q192R (human)
associated with Diabetes Mellitus, Type 2;DNA:missense mutation:cds:p.Q192R (human)
CTD
ClinVar
PMID:7916578 PMID:8098250 PMID:8675673 PMID:8770857 PMID:9011577 PMID:9215303 PMID:9385372 PMID:9443884 PMID:9661650 PMID:11238489 PMID:11335891 PMID:11788650 PMID:11810302 PMID:11888590 PMID:11889198 PMID:11918623 PMID:12082503 PMID:15241482 PMID:16353344 PMID:16882531 PMID:21170047, PMID:19005291, PMID:15214960, PMID:9215303 RGD:2313267, RGD:8547675, RGD:1580201 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Pon2 paraoxonase 2 susceptibility ISO DNA:missense mutation:cds:p.C311S (human) RGD PMID:9443862 RGD:1580216 NCBI chr 4:30,344,705...30,380,119
Ensembl chr 4:30,344,709...30,380,119
JBrowse link
G Retn resistin ISO protein:increased expression:blood RGD PMID:17175295 RGD:7207156 NCBI chr12:2,201,909...2,203,649
Ensembl chr12:2,201,891...2,204,249
JBrowse link
G Scarb1 scavenger receptor class B, member 1 ISO RGD PMID:15967843 RGD:1580004 NCBI chr12:36,694,952...36,761,445
Ensembl chr12:36,694,960...36,761,455
JBrowse link
G Selp selectin P ISO protein:altered expression:serum RGD PMID:11597943 RGD:1580074 NCBI chr13:82,428,914...82,464,629
Ensembl chr13:82,429,063...82,464,628
JBrowse link
G Serpinf2 serpin family F member 2 ISO protein:increased expression:blood RGD PMID:15771120 RGD:1625529 NCBI chr10:62,264,247...62,272,353
Ensembl chr10:62,264,788...62,273,119
JBrowse link
G Tcf7l2 transcription factor 7 like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28869590 NCBI chr 1:276,686,911...276,730,517
Ensembl chr 1:276,659,542...276,730,514
Ensembl chr 1:276,659,542...276,730,514
JBrowse link
G Tert telomerase reverse transcriptase ISO ClinVar Annotator: match by term: Coronary artery disease, susceptibility to ClinVar PMID:16890917 NCBI chr 1:32,250,876...32,275,330
Ensembl chr 1:32,251,714...32,272,476
JBrowse link
G Thbd thrombomodulin ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:plasma RGD PMID:17200788 RGD:2312456 NCBI chr 3:142,748,673...142,752,325
Ensembl chr 3:142,748,674...142,752,325
JBrowse link
G Vegfa vascular endothelial growth factor A ISO mRNA, protein:increased expression:ventricle myocardium RGD PMID:16139132 RGD:2313728 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16549638 NCBI chr 1:199,338,785...199,341,306
Ensembl chr 1:199,337,138...199,341,302
JBrowse link
G Vwf von Willebrand factor ISO RGD PMID:11864703 RGD:1580647 NCBI chr 4:158,085,059...158,219,525
Ensembl chr 4:158,088,505...158,219,523
JBrowse link
G Zc3hc1 zinc finger, C3HC-type containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28869590 NCBI chr 4:57,684,678...57,706,613
Ensembl chr 4:57,684,678...57,706,613
JBrowse link
Coronary Occlusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 disease_progression ISO RGD PMID:26315408 RGD:14367880 NCBI chr 8:77,640,234...77,719,488
Ensembl chr 8:77,640,222...77,719,489
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A ISO mRNA:increased expression:heart: RGD PMID:21439970 RGD:7257651 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
coronary restenosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme ISO CTD Direct Evidence: marker/mechanism CTD PMID:9236417 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO CTD Direct Evidence: therapeutic CTD PMID:12138120 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Bche butyrylcholinesterase susceptibility ISO DNA:polymorphism: :p.A539T (human) RGD PMID:17275003 RGD:2306778 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
G Cdh13 cadherin 13 IEP protein:increased expression:artery, smooth muscle cell RGD PMID:12376824 RGD:2293553 NCBI chr19:50,848,793...51,971,618
Ensembl chr19:50,848,736...51,972,103
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 ISO protein:increased expression:plasma RGD PMID:14578618 RGD:1598500 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 ISO RGD PMID:14578618 RGD:1598500 NCBI chr  X:71,614,346...71,616,997
Ensembl chr  X:71,614,346...71,616,997
JBrowse link
G F2r coagulation factor II (thrombin) receptor ISO RGD PMID:14529396 RGD:1581036 NCBI chr 2:26,118,760...26,135,340
Ensembl chr 2:26,118,760...26,135,340
JBrowse link
G Hmox1 heme oxygenase 1 susceptibility ISO RGD PMID:16020495, PMID:14529548 RGD:1598402, RGD:1580472 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Itgb2 integrin subunit beta 2 ISO RGD PMID:11703955 RGD:1581185 NCBI chr20:11,777,773...11,815,647
Ensembl chr20:11,777,783...11,815,647
JBrowse link
G Lox lysyl oxidase IDA RGD PMID:15218472 RGD:1581881 NCBI chr18:47,500,320...47,577,819
Ensembl chr18:47,500,330...47,577,819
JBrowse link
G Mapk1 mitogen activated protein kinase 1 IDA RGD PMID:15583728 RGD:1582284 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mbl2 mannose binding lectin 2 susceptibility ISO DNA:polymorphisms:5' utr, exon:multiple (human) RGD PMID:15790942 RGD:1582150 NCBI chr 1:248,435,069...248,442,669
Ensembl chr 1:248,723,397...248,729,962
JBrowse link
G Mmp3 matrix metallopeptidase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8662692 NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579
JBrowse link
G Mmp7 matrix metallopeptidase 7 treatment IEP RGD PMID:21139058 RGD:9685362 NCBI chr 8:5,893,253...5,900,965
Ensembl chr 8:5,893,249...5,901,049
JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16489563 NCBI chr 5:164,844,642...164,864,360
Ensembl chr 5:164,845,925...164,860,910
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor treatment IDA RGD PMID:7955204 RGD:10059621 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Npy5r neuropeptide Y receptor Y5 IEP mRNA, protein:increased expression:carotid artery RGD PMID:12689918 RGD:1625501 NCBI chr16:24,796,685...24,805,730
Ensembl chr16:24,797,124...24,805,079
JBrowse link
G Spp1 secreted phosphoprotein 1 ISO RGD PMID:12114325, PMID:16373617 RGD:1581358, RGD:1581366 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:16319143, PMID:16319143 RGD:1580322 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tp53 tumor protein p53 ISO RGD PMID:14740296 RGD:1580742 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Ucp3 uncoupling protein 3 susceptibility ISO DNA:polymorphism:promoter:-55C>T (human) RGD PMID:17786284 RGD:2313513 NCBI chr 1:165,482,912...165,495,895
Ensembl chr 1:165,482,155...165,496,206
JBrowse link
coronary stenosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apln apelin ISO protein:decreased expression:plasma RGD PMID:19015606 RGD:2313942 NCBI chr  X:134,856,719...134,866,210
Ensembl chr  X:134,856,726...134,866,210
JBrowse link
G Edn1 endothelin 1 treatment ISO RGD PMID:10854676 RGD:8661796 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Hrh2 histamine receptor H 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12721106 NCBI chr17:10,912,959...10,931,389
Ensembl chr17:10,921,507...10,952,441
JBrowse link
G Igf1 insulin-like growth factor 1 IEP mRNA:increased expression:myocyte: RGD PMID:8102103 RGD:10046053 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igf1r insulin-like growth factor 1 receptor IEP mRNA:increased expression:myocyte: RGD PMID:8102103 RGD:10046053 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Itgav integrin subunit alpha V IDA RGD PMID:11922905 RGD:1582454 NCBI chr 3:71,113,269...71,205,958
Ensembl chr 3:71,114,100...71,202,411
JBrowse link
G Mdk midkine IDA RGD PMID:10683378 RGD:1299187 NCBI chr 3:80,841,003...80,843,895
Ensembl chr 3:80,841,005...80,842,916
JBrowse link
G Myh7 myosin heavy chain 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12721106 NCBI chr15:33,605,769...33,657,761
Ensembl chr15:33,634,422...33,656,089
JBrowse link
G Nppa natriuretic peptide A ISO CTD Direct Evidence: marker/mechanism CTD PMID:12721106 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 ISO DNA:missense mutations:cds:p.L125V, p.S563N (human) RGD PMID:10571959 RGD:1598382 NCBI chr10:94,850,971...94,913,202 JBrowse link
G Prkce protein kinase C, epsilon ISO CTD Direct Evidence: marker/mechanism CTD PMID:16782078 NCBI chr 6:9,483,400...9,973,396
Ensembl chr 6:9,790,422...9,973,396
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B ISO protein:increased expression:serum RGD PMID:15569000 RGD:1624167 NCBI chr 7:93,798,580...93,826,586
Ensembl chr 7:93,798,545...93,826,665
JBrowse link
coronary thrombosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itgb3 integrin subunit beta 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8598867 NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410
JBrowse link
G Plat plasminogen activator, tissue type ISO CTD Direct Evidence: therapeutic CTD PMID:1452937 PMID:8172379 PMID:15301905 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
JBrowse link
Hypertension Resistant to Conventional Therapy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gstm1 glutathione S-transferase mu 1 susceptibility ISO DNA:deletion:cds: (human) RGD PMID:19279659 RGD:7495846 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Nos3 nitric oxide synthase 3 ISO ClinVar Annotator: match by term: Hypertension resistant to conventional therapy ClinVar PMID:9737779 PMID:9894802 PMID:10475066 PMID:10510054 PMID:10514107 PMID:11026457 PMID:11354626 PMID:11394896 PMID:11745998 PMID:15007011 PMID:16059745 PMID:16813604 PMID:17165044 PMID:24033266 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
intermediate coronary syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme ISO mRNA:increased expression:ventricular myocardium (human)
mRNA:increased expression:myocardium
RGD PMID:15131005, PMID:11451295 RGD:8142363, RGD:8548894 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Agt angiotensinogen ISO mRNA:increased expression:myocardium RGD PMID:11451295 RGD:8548894 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Agtr1a angiotensin II receptor, type 1a ISO mRNA:increased expression:myocardium RGD PMID:11451295 RGD:8548894 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077
JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO protein:increased serine phosphorylation:platelet RGD PMID:20467748 RGD:5509094 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Apoa4 apolipoprotein A4 ISO protein:decreased expression:blood plasma (human) RGD PMID:20367977 RGD:5685646 NCBI chr 8:50,536,983...50,539,371
Ensembl chr 8:50,537,009...50,539,376
JBrowse link
G Bdnf brain-derived neurotrophic factor ISO RGD PMID:16186425 RGD:4891111 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Crp C-reactive protein disease_progression ISO RGD PMID:9761079 RGD:9491780 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Edn1 endothelin 1 ISO associated with Coronary Artery Disease;protein:increased expression:coronary sinus, plasma (human) RGD PMID:14556009 RGD:8661755 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G F7 coagulation factor VII ISO protein:increased expression:plasma (human) RGD PMID:10653827 RGD:2312399 NCBI chr16:81,824,610...81,834,923
Ensembl chr16:81,824,111...81,834,945
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase ISO RGD PMID:18333374 RGD:5508458 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Itga2 integrin subunit alpha 2 susceptibility ISO RGD PMID:15104219 RGD:1582303 NCBI chr 2:46,996,904...47,097,011
Ensembl chr 2:47,000,323...47,096,961
JBrowse link
G Itih4 inter-alpha-trypsin inhibitor heavy chain 4 ISO RGD PMID:10486281 RGD:1582334 NCBI chr16:6,970,367...6,985,538
Ensembl chr16:6,970,342...6,985,579
JBrowse link
G Mmp1 matrix metallopeptidase 1 ISO RGD PMID:14675588 RGD:1582536 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Pappa1 pappalysin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11586954 NCBI chr 5:80,919,932...81,153,904
Ensembl chr 5:80,920,568...81,150,940
JBrowse link
G Plau plasminogen activator, urokinase ISO CTD Direct Evidence: therapeutic CTD PMID:2382605 NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819
JBrowse link
G Selp selectin P ISO protein:increased expression:serum RGD PMID:21162967 RGD:6219003 NCBI chr13:82,428,914...82,464,629
Ensembl chr13:82,429,063...82,464,628
JBrowse link
G Serpinc1 serpin family C member 1 treatment ISO RGD PMID:8122184 RGD:11035255 NCBI chr13:78,806,107...78,820,375
Ensembl chr13:78,805,347...78,833,192
JBrowse link
G Sod3 superoxide dismutase 3 ISO RGD PMID:14592844 RGD:1580841 NCBI chr14:60,958,583...60,971,143
Ensembl chr14:60,958,592...60,964,324
JBrowse link
G Txn1 thioredoxin 1 ISO RGD PMID:15749180 RGD:1580784 NCBI chr 5:75,049,735...75,057,731
Ensembl chr 5:75,049,747...75,057,752
JBrowse link
Medial Coronary Sclerosis of Infancy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 ISO ClinVar Annotator: match by term: Coronary sclerosis, medial, of infancy ClinVar PMID:15940697 PMID:25741868 NCBI chr 1:21,748,201...21,813,205
Ensembl chr 1:21,748,261...21,813,371
JBrowse link
Microvascular Angina term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdkrb1 bradykinin receptor B1 ISO mRNA:increased expression:blood, mononuclear cell RGD PMID:17852785 RGD:4890450 NCBI chr 6:129,437,423...129,441,553
Ensembl chr 6:129,438,158...129,440,574
JBrowse link
G Bdkrb2 bradykinin receptor B2 ISO mRNA:increased expression:blood, mononuclear cell RGD PMID:17852785 RGD:4890450 NCBI chr 6:129,399,468...129,429,676
Ensembl chr 6:129,399,468...129,429,676
JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO DNA:transition:cds:g.677C>T (human)
CTD Direct Evidence: marker/mechanism
CTD PMID:17491230, PMID:17491230 RGD:4891159 NCBI chr 5:164,844,642...164,864,360
Ensembl chr 5:164,845,925...164,860,910
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B ISO protein:decreased expression:serum RGD PMID:15648548 RGD:1620974 NCBI chr 7:93,798,580...93,826,586
Ensembl chr 7:93,798,545...93,826,665
JBrowse link
myocardial infarction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc9 ATP binding cassette subfamily C member 9 ISO ClinVar Annotator: match by term: Myocardial infarction, susceptibility to ClinVar PMID:16563363 PMID:23861362 PMID:24033266 PMID:25741868 PMID:28492532 NCBI chr 4:176,806,098...176,928,540
Ensembl chr 4:176,805,431...176,922,424
JBrowse link
G Ace angiotensin I converting enzyme treatment
susceptibility
ISO
IEP
IMP
ClinVar Annotator: match by term: Heart attack
CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Type 1;DNA:deletion:intron:IVS16+1464-1751del (human)
associated with Myocardial Reperfusion Injury
ClinVar
CTD
PMID:1313972 PMID:1319114 PMID:1328889 PMID:1386652 PMID:1976655 PMID:2847529 PMID:2849100 PMID:7593601 PMID:7729604 PMID:7854377 PMID:7909524 PMID:8131299 PMID:8131300 PMID:8136829 PMID:8170965 PMID:8208911 PMID:8298638 PMID:8314010 PMID:8541160 PMID:8644984 PMID:8675669 PMID:9120002 PMID:9236417 PMID:9259580 PMID:9699903 PMID:9737775 PMID:9916793 PMID:10099885 PMID:10636736 PMID:10643899 PMID:10841123 PMID:11687636 PMID:11956052 PMID:12220450 PMID:12666117 PMID:14657821 PMID:14872014 PMID:15110771 PMID:15277638 PMID:15381116 PMID:15531537 PMID:15534175 PMID:15635071 PMID:19221299, PMID:15118671, PMID:23959549, PMID:15671045, PMID:7555560, PMID:21975128 RGD:1331525, RGD:9685449, RGD:1558664, RGD:7829785, RGD:6893480 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Ace2 angiotensin I converting enzyme 2 treatment IEP
IDA
mRNA:increased expression:myocardium RGD PMID:15671045, PMID:23959549 RGD:1558664, RGD:9685449 NCBI chr  X:32,050,734...32,095,860
Ensembl chr  X:32,049,931...32,096,016
JBrowse link
G Acta2 actin alpha 2, smooth muscle ISO CTD Direct Evidence: marker/mechanism CTD PMID:24358288 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 IEP RGD PMID:15625312 RGD:9681751 NCBI chr11:25,342,119...25,350,938
Ensembl chr11:25,342,126...25,350,974
JBrowse link
G Add1 adducin 1 no_association ISO DNA:missense mutation:cds:p.G460W (human) RGD PMID:17082469, PMID:16420563 RGD:5147995, RGD:5148001 NCBI chr14:81,367,466...81,426,610
Ensembl chr14:81,367,468...81,426,496
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing disease_progression IEP RGD PMID:21326342 RGD:5686351 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Adipor1 adiponectin receptor 1 ISO mRNA, protein:decreased expression:heart left ventricle RGD PMID:16415076 RGD:1625764 NCBI chr13:51,240,470...51,260,233
Ensembl chr13:51,240,911...51,260,228
JBrowse link
G Adipor2 adiponectin receptor 2 ISO mRNA, protein:decreased expression:heart left ventricle RGD PMID:16415076 RGD:1625764 NCBI chr 4:151,412,135...151,480,108
Ensembl chr 4:151,414,684...151,428,894
JBrowse link
G Adora1 adenosine A1 receptor ISO CTD Direct Evidence: therapeutic CTD PMID:12160945 NCBI chr13:51,042,111...51,076,913
Ensembl chr13:51,042,248...51,076,852
JBrowse link
G Adora3 adenosine A3 receptor ISO CTD Direct Evidence: therapeutic CTD PMID:12160945 PMID:20132822 NCBI chr 2:208,336,909...208,379,217
Ensembl chr 2:208,373,154...208,376,803
JBrowse link
G Adra2b adrenoceptor alpha 2B ISO RGD PMID:12535806 RGD:1559314 NCBI chr 3:119,805,941...119,809,987
Ensembl chr 3:119,805,941...119,809,987
JBrowse link
G Adrb1 adrenoceptor beta 1 ISO
IMP
GAD
RGD
PMID:15118671, PMID:17143192 RGD:1331525, RGD:7241557 NCBI chr 1:277,537,585...277,538,985
Ensembl chr 1:277,537,585...277,538,985
JBrowse link
G Adrb2 adrenoceptor beta 2 susceptibility ISO
IEP
DNA:polymorphisms: :p.G16R, p.Q27E, p.T164I
mRNA:decreased expression:heart
RGD PMID:15520258, PMID:12400771 RGD:1601126, RGD:8548519 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834
JBrowse link
G Ager advanced glycosylation end product-specific receptor susceptibility IEP
ISO
mRNA:increased expression:left ventricle myocardium (rat)
DNA:polymorphism:promoter:-429T>C (human)
RGD PMID:19910580, PMID:16728681 RGD:2325647, RGD:1625333 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Agt angiotensinogen susceptibility IDA
ISO
CTD Direct Evidence: marker/mechanism
associated with Coronary Artery Disease;DNA:polymorphism: :p.M235T (human)
associated with hypertension;DNA:polymorphism: :p.M235T