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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Amyloid Plaques
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Accession:DOID:9005832 term browser browse the term
Definition:Accumulations of extracellularly deposited AMYLOID FIBRILS within tissues.
Synonyms:exact_synonym: Amyloid Deposit;   Neuritic Plaque;   Neuritic Plaques;   Senile Plaque;   amyloid deposits;   amyloid plaque;   senile plaques
 primary_id: MESH:D058225
 alt_id: OMIM:269800


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Amyloid Plaques term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:19818510 PMID:29729307 PMID:31939705 PMID:33096116 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Bche butyrylcholinesterase ISO RGD PMID:22157615 RGD:5687325 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148 		JBrowse link
G Bdnf brain-derived neurotrophic factor ISO RGD PMID:15014117 RGD:10059349 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Maob monoamine oxidase B ISO CTD Direct Evidence: marker/mechanism CTD PMID:7816197 NCBI chr  X:5,907,327...6,010,996
Ensembl chr  X:5,907,266...6,011,003 		JBrowse link
G Psen1 presenilin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:33096116 NCBI chr 6:103,323,052...103,375,088
Ensembl chr 6:103,323,120...103,371,650 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18976
    Pathological Conditions, Signs and Symptoms 13376
      Anatomical Pathological Conditions 2664
        Amyloid Plaques 5
          Dementia/Parkinsonism with Non-Alzheimer Amyloid Plaques 0
paths to the root