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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:clonorchiasis
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Accession:DOID:13767 term browser browse the term
Definition:A parasitic helminthiasis infectious disease that involves parasitic infection of the bile ducts of the liver by Clonorchis sinensis. The symptoms include abdominal pain, nausea, diarrhea, and eosinophilia. In long-standing infections, cholangitis, cholelithiasis, pancreatitis, and cholangiocarcinoma can develop. (DO)
Synonyms:exact_synonym: clonorchiases;   oriental liver fluke disease
 primary_id: MESH:D003003
 xref: EFO:0007210;   ICD10CM:B66.1;   ICD9CM:121.1
For additional species annotation, visit the Alliance of Genome Resources.


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clonorchiasis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fas Fas cell surface death receptor IEP mRNA, protein:increased expression:liver RGD PMID:18427836 RGD:2315733 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Faslg Fas ligand IEP mRNA, protein:increased expression:liver RGD PMID:18427836 RGD:2315733 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Il33 interleukin 33 ISO mRNA,protein:increased expression:liver, serum:
protein:increased expression:serum:		 RGD PMID:26944417 PMID:26944417 RGD:39939001, RGD:39939001 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373 		JBrowse link
G Tlr2 toll-like receptor 2 ISO RGD PMID:28784165 RGD:15090810 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18969
    disease of anatomical entity 18249
      endocrine system disease 6821
        liver disease 2958
          clonorchiasis 4
Path 2
Term Annotations click to browse term
  disease 18969
    disease by infectious agent 2215
      parasitic infectious disease 327
        parasitic helminthiasis infectious disease 83
          Trematode Infections 41
            fasciolopsiasis 41
              clonorchiasis 4
paths to the root