Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:fasciolopsiasis
go back to main search page
Accession:DOID:888 term browser browse the term
Definition:A parasitic helminthiasis infectious disease that involves parasitic infection of the intestine by Fasciolopsis buski. The symptoms include diarrhea, abdominal pain, fever, ascites, anasarca and intestinal obstruction. (DO)
Synonyms:exact_synonym: fasciolopsiases;   infection by Fasciolopsis buski;   infectious disease by Fasciolopsis
 broad_synonym: Trematode Infection;   Trematode Infections
 primary_id: MESH:D014201
 xref: ICD10CM:B66.5;   ICD9CM:121.4;   NCI:C128388
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
clonorchiasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fas Fas cell surface death receptor IEP mRNA, protein:increased expression:liver RGD PMID:18427836 RGD:2315733 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Faslg Fas ligand IEP mRNA, protein:increased expression:liver RGD PMID:18427836 RGD:2315733 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Il33 interleukin 33 ISO mRNA,protein:increased expression:liver, serum:
protein:increased expression:serum:		 RGD PMID:26944417 PMID:26944417 RGD:39939001, RGD:39939001 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373 		JBrowse link
G Tlr2 toll-like receptor 2 ISO RGD PMID:28784165 RGD:15090810 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
fascioliasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctsb cathepsin B IEP protein:decreased activity:liver (rat) RGD PMID:19696938 RGD:2315504 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500 		JBrowse link
G Glud1 glutamate dehydrogenase 1 IEP protein:increased expression:serum RGD PMID:10431747 RGD:6484593 NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957 		JBrowse link
hepatosplenic schistosomiasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd209a CD209a molecule ISO mRNA,protein:decreased expression:spleen,liver (mouse) RGD PMID:29386115 PMID:24729611 RGD:39938990, RGD:39938995 NCBI chr12:1,822,663...1,828,246
Ensembl chr12:1,822,663...1,828,246 		JBrowse link
G Clec4m C-type lectin domain family 4 member M ISO RGD PMID:18981244 RGD:39938988 NCBI chr12:1,915,902...1,924,529
Ensembl chr12:1,915,919...1,924,539 		JBrowse link
G Krt18 keratin 18 disease_progression ISO protein:increased expression:serum (mouse, human) RGD PMID:21357724 RGD:21406434 NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166 		JBrowse link
G Mir146a microRNA 146a ISO miRNA:increased expression:liver, hepatic stellate cell (mouse)
miRNA:increased expression:liver, macrophage (mouse)
miRNA:increased expression:liver (mouse)		 RGD PMID:25116007 PMID:27780686 PMID:25051829 RGD:126925174, RGD:126925179, RGD:126925180 NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610 		JBrowse link
G Serpinf1 serpin family F member 1 ISO RGD PMID:9038736 RGD:30296660 NCBI chr10:60,250,198...60,262,593
Ensembl chr10:60,249,708...60,262,646 		JBrowse link
opisthorchiasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actr3 actin related protein 3 ISO RGD PMID:25809205 RGD:11570559 NCBI chr13:36,800,739...36,843,837
Ensembl chr13:36,800,093...36,844,124 		JBrowse link
G Mir192 microRNA 192 ISO RNA:increased expression:urine RGD PMID:26456596 RGD:41404678 NCBI chr 1:203,564,946...203,565,055
Ensembl chr 1:203,564,946...203,565,055 		JBrowse link
schistosomiasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor ISO protein:decreased expression:lung (mouse) RGD PMID:23369670 RGD:7243187 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Bud31 BUD31 homolog IEP Protein:increased expression:serum (human) RGD PMID:22686541 RGD:10058982 NCBI chr12:9,462,838...9,470,387
Ensembl chr12:9,462,441...9,470,509 		JBrowse link
G Il33 interleukin 33 ISO mRNA,protein:increased expression:liver RGD PMID:29554131 RGD:39938854 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373 		JBrowse link
G Mir146a microRNA 146a disease_progression ISO miRNA:altered expression: blood serum (mouse) RGD PMID:32443549 RGD:126925171 NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610 		JBrowse link
G Prdx1 peroxiredoxin 1 ISO CTD Direct Evidence: therapeutic CTD PMID:19041905 NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856 		JBrowse link
G Rassf1 Ras association domain family member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23527093 NCBI chr 8:108,225,023...108,236,164
Ensembl chr 8:108,225,023...108,236,164 		JBrowse link
G RT1-Db1 RT1 class II, locus Db1 treatment ISO DNA:polymorphism: :HLA-DRB1*13 RGD PMID:16709874 RGD:36049813 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258 		JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 ISO RGD PMID:32404867 RGD:39128195 NCBI chr18:27,332,119...27,338,371
Ensembl chr18:27,332,119...27,338,335 		JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23527093 NCBI chr 7:17,520,827...17,571,850
Ensembl chr 7:17,521,919...17,571,839 		JBrowse link
Schistosomiasis Japonica term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd1d1 CD1d1 molecule treatment ISO RGD PMID:33283278 RGD:127345110 NCBI chr 2:172,423,582...172,427,089
Ensembl chr 2:172,423,582...172,427,089 		JBrowse link
G Il18 interleukin 18 treatment ISO RGD PMID:19467215 RGD:14696662 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il33 interleukin 33 treatment
severity		 ISO protein:increased expression:serum RGD PMID:22590860 PMID:25944738 PMID:25944738 RGD:39939027, RGD:40400890, RGD:40400890 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373 		JBrowse link
G Mir223 microRNA 223 treatment ISO RNA:increased expression:plasma: RGD PMID:24330517 PMID:24330517 RGD:21408589, RGD:21408589 NCBI chr  X:61,141,887...61,141,996
Ensembl chr  X:61,141,887...61,141,996 		JBrowse link
G Pdcd1 programmed cell death 1 severity ISO protein:increased expression:CD4 T cell RGD PMID:27792733 PMID:27792733 PMID:27792733 RGD:40818413, RGD:40818413, RGD:40818413 NCBI chr 9:94,418,786...94,431,945
Ensembl chr 9:94,418,791...94,431,937 		JBrowse link
G RT1-Ba RT1 class II, locus Ba susceptibility ISO DNA:polymorphisms: : RGD PMID:16042197 RGD:14398841 NCBI chr20:4,575,134...4,579,727
Ensembl chr20:4,575,134...4,579,744 		JBrowse link
G Serpinh1 serpin family H member 1 ISO mRNA,protein:increased expression:liver, serum (mouse) RGD PMID:31612672 RGD:41412161 NCBI chr 1:153,643,500...153,650,853
Ensembl chr 1:153,643,510...153,650,801 		JBrowse link
Schistosomiasis Mansoni term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 ISO mRNA:increased expression:macrophage RGD PMID:22927819 RGD:14367882 NCBI chr 8:71,877,850...71,957,107
Ensembl chr 8:71,877,850...71,957,107 		JBrowse link
G Cd40 CD40 molecule treatment ISO RGD PMID:10623823 RGD:11520789 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534 		JBrowse link
G Cd86 CD86 molecule ISO protein:increased expression:peripheral blood, eosinophil (human) RGD PMID:17308795 RGD:11354987 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818 		JBrowse link
G Ihh Indian hedgehog signaling molecule ISO RGD PMID:23121638 RGD:12910981 NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532 		JBrowse link
G Il13 interleukin 13 treatment IMP RGD PMID:10903803 RGD:8549615 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737 		JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 exacerbates ISO RGD PMID:27487182 RGD:151356963 NCBI chr17:53,382,908...53,403,216
Ensembl chr17:53,383,131...53,403,216 		JBrowse link
G Nos2 nitric oxide synthase 2 ISO CTD Direct Evidence: therapeutic CTD PMID:9673227 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Sod1 superoxide dismutase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16564582 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Tlr9 toll-like receptor 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19797157 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796 		JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 ISO RGD PMID:21332515 RGD:126925988 NCBI chr 9:12,763,819...12,779,285
Ensembl chr 9:12,763,819...12,779,203 		JBrowse link
G Tslp thymic stromal lymphopoietin treatment ISO RGD PMID:22882457 RGD:38596354 NCBI chr18:24,447,409...24,454,244
Ensembl chr18:24,449,844...24,453,548 		JBrowse link
urinary schistosomiasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd1d1 CD1d1 molecule ISO protein:increased expression:B cell (human) RGD PMID:22347409 RGD:127345101 NCBI chr 2:172,423,582...172,427,089
Ensembl chr 2:172,423,582...172,427,089 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 susceptibility ISO DNA:SNPs:multiple:Gabonese(human) RGD PMID:22288822 RGD:7204674 NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963 		JBrowse link
G Il5 interleukin 5 resistance ISO RGD PMID:9697734 RGD:7241010 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 severity ISO DNA:SNP:enhancer: (rs324013) RGD PMID:18273035 RGD:7243977 NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19051
    disease by infectious agent 2249
      parasitic infectious disease 327
        parasitic helminthiasis infectious disease 83
          fasciolopsiasis 41
            clonorchiasis 4
            dicrocoeliasis 0
            echinostomiasis 0
            fascioliasis 2
            fascioloidiasis 0
            heterophyiasis 0
            opisthorchiasis 2
            paragonimiasis 0
            philophthalmiasis 0
            schistosomiasis + 34
Path 2
Term Annotations click to browse term
  disease 19051
    disease by infectious agent 2249
      parasitic infectious disease 327
        parasitic helminthiasis infectious disease 83
          Trematode Infections 41
            fasciolopsiasis 41
              clonorchiasis 4
              dicrocoeliasis 0
              echinostomiasis 0
              fascioliasis 2
              fascioloidiasis 0
              heterophyiasis 0
              opisthorchiasis 2
              paragonimiasis 0
              philophthalmiasis 0
              schistosomiasis + 34
paths to the root