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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:vulva carcinoma
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Accession:DOID:1294 term browser browse the term
Definition:A vulva cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells. (DO)
Synonyms:exact_synonym: carcinoma of vulva;   vulvar carcinoma
 xref: EFO:0002921;   NCI:C4866
For additional species annotation, visit the Alliance of Genome Resources.


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vulva squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc25a cell division cycle 25A ISO protein:increased expression:vulva RGD PMID:20500813 RGD:2729590 NCBI chr 8:109,864,356...109,882,734
Ensembl chr 8:109,864,478...109,882,701 		JBrowse link
G Cdc25b cell division cycle 25B disease_progression ISO protein:increased expression:vulva RGD PMID:20500813 RGD:2729590 NCBI chr 3:118,407,127...118,417,272
Ensembl chr 3:118,407,128...118,417,272 		JBrowse link
G Cdc25c cell division cycle 25C disease_progression ISO protein:increased expression:vulva RGD PMID:20500813 RGD:2729590 NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185 		JBrowse link
G Sfn stratifin ISO DNA, mRNA:hypermethylation, decreased expression:vulva RGD PMID:11896620 RGD:2299936 NCBI chr 5:145,826,722...145,827,994
Ensembl chr 5:145,826,201...145,831,314 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18969
    disease of cellular proliferation 7691
      cancer 5508
        cell type cancer 3761
          carcinoma 3202
            vulva carcinoma 4
              Bartholin's gland carcinoma + 0
              labia majora carcinoma 0
              labia minora carcinoma 0
              vulva adenocarcinoma + 0
              vulva basal cell carcinoma 0
              vulva squamous cell carcinoma + 4
              vulvar clear cell hidradenocarcinoma 0
              vulvar eccrine porocarcinoma 0
              vulvar sebaceous carcinoma 0
Path 2
Term Annotations click to browse term
  disease 18969
    disease of anatomical entity 18249
      Urogenital Diseases 5233
        Female Urogenital Diseases and Pregnancy Complications 2456
          Female Urogenital Diseases 2003
            female reproductive system disease 2000
              Female Genital Neoplasms 845
                Vulvar Neoplasms 19
                  vulva cancer 11
                    vulva carcinoma 4
                      Bartholin's gland carcinoma + 0
                      labia majora carcinoma 0
                      labia minora carcinoma 0
                      vulva adenocarcinoma + 0
                      vulva basal cell carcinoma 0
                      vulva squamous cell carcinoma + 4
                      vulvar clear cell hidradenocarcinoma 0
                      vulvar eccrine porocarcinoma 0
                      vulvar sebaceous carcinoma 0
paths to the root