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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:vulva squamous cell carcinoma
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Accession:DOID:2101 term browser browse the term
Definition:A vulva carcinoma and has_material_basis_in squamous cells and is located_in the epidermis of the vulvar tissue. (DO)
Synonyms:exact_synonym: squamous cell carcinoma of vulva;   vulvar epidermoid carcinoma;   vulvar squamous cell carcinoma
 xref: NCI:C4052;   ORDO:494448
For additional species annotation, visit the Alliance of Genome Resources.



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vulva squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc25a cell division cycle 25A ISO protein:increased expression:vulva RGD PMID:20500813 RGD:2729590 NCBI chr 8:109,864,356...109,882,734
Ensembl chr 8:109,864,478...109,882,701
JBrowse link
G Cdc25b cell division cycle 25B disease_progression ISO protein:increased expression:vulva RGD PMID:20500813 RGD:2729590 NCBI chr 3:118,407,127...118,417,272
Ensembl chr 3:118,407,128...118,417,272
JBrowse link
G Cdc25c cell division cycle 25C disease_progression ISO protein:increased expression:vulva RGD PMID:20500813 RGD:2729590 NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185
JBrowse link
G Sfn stratifin ISO DNA, mRNA:hypermethylation, decreased expression:vulva RGD PMID:11896620 RGD:2299936 Ensembl chr 5:145,826,201...145,831,314 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17240
    disease of cellular proliferation 7045
      Neoplasms by Histologic Type 4774
        cell type cancer 3406
          carcinoma 2925
            vulva carcinoma 4
              vulva squamous cell carcinoma 4
                Bartholin's gland squamous cell carcinoma + 0
                vulva verrucous carcinoma 0
                vulvar basaloid squamous cell carcinoma 0
                vulvar keratinizing squamous cell carcinoma 0
                vulvar keratoacanthoma-like carcinoma 0
                vulvar non-keratinizing squamous cell carcinoma 0
Path 2
Term Annotations click to browse term
  disease 17240
    disease of anatomical entity 16581
      Urogenital Diseases 4360
        Female Urogenital Diseases and Pregnancy Complications 2047
          Female Urogenital Diseases 1742
            female reproductive system disease 1738
              Female Genital Neoplasms 704
                female reproductive organ cancer 519
                  vulva cancer 10
                    vulva carcinoma 4
                      vulva squamous cell carcinoma 4
                        Bartholin's gland squamous cell carcinoma + 0
                        vulva verrucous carcinoma 0
                        vulvar basaloid squamous cell carcinoma 0
                        vulvar keratinizing squamous cell carcinoma 0
                        vulvar keratoacanthoma-like carcinoma 0
                        vulvar non-keratinizing squamous cell carcinoma 0
paths to the root