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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:dipicolinic acid
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Accession:CHEBI:46837 term browser browse the term
Definition:A pyridinedicarboxylic acid carrying two carboxy groups at positions 2 and 6.
Synonyms:related_synonym: 2,6-Dipicolinic acid;   2,6-dicarboxypyridine;   2,6-pyridinedicarboxylic acid;   Formula=C7H5NO4;   InChI=1S/C7H5NO4/c9-6(10)4-2-1-3-5(8-4)7(11)12/h1-3H,(H,9,10)(H,11,12);   InChIKey=WJJMNDUMQPNECX-UHFFFAOYSA-N;   PYRIDINE-2,6-DICARBOXYLIC ACID;   SMILES=OC(=O)c1cccc(n1)C(O)=O
 alt_id: CHEBI:36171;   CHEBI:44858
 xref: Beilstein:131629;   CAS:499-83-2;   DrugBank:DB04267;   Gmelin:50798;   HMDB:HMDB0033161
 xref_mesh: MESH:C004860
 xref: PDBeChem:PDC;   PMID:23396907;   PMID:24123749;   Patent:US5298478;   Reaxys:131629;   Wikipedia:Dipicolinic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:46835


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dipicolinic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Glud1 glutamate dehydrogenase 1 multiple interactions
decreases activity		 ISO dipicolinic acid inhibits the reaction [[GLUD1 protein co-treated with Ketoglutaric Acids co-treated with NADP co-treated with Aminooxyacetic Acid] affects the reaction [Carbon Tetrachloride affects the abundance of Ammonia]]
dipicolinic acid results in decreased activity of GLUD1 protein		 CTD PMID:26639393 NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957 		JBrowse link
G Mapt microtubule-associated protein tau multiple interactions ISO dipicolinic acid promotes the reaction [MAPT protein binds to MAPT protein] CTD PMID:31678113 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19838
    role 19814
      application 19658
        NMR chemical shift reference compound 17961
          pyridine 51
            pyridinedicarboxylic acid 30
              dipicolinic acid 2
                (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid 0
                2,3,4,5-tetrahydrodipicolinic acid + 0
                3-(2-deoxy-5-O-phosphonoribofuranosyl)pyridine-2,6-dicarboxylic acid 0
                dihydrodipicolinic acid + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19838
    subatomic particle 19836
      composite particle 19836
        hadron 19836
          baryon 19836
            nucleon 19836
              atomic nucleus 19836
                atom 19836
                  main group element atom 19786
                    p-block element atom 19786
                      carbon group element atom 19734
                        carbon atom 19731
                          organic molecular entity 19731
                            organic molecule 19684
                              organic cyclic compound 19496
                                organic heterocyclic compound 18874
                                  organic heteromonocyclic compound 17801
                                    pyridines 11521
                                      pyridine 51
                                        pyridinedicarboxylic acid 30
                                          dipicolinic acid 2
                                            (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid 0
                                            2,3,4,5-tetrahydrodipicolinic acid + 0
                                            3-(2-deoxy-5-O-phosphonoribofuranosyl)pyridine-2,6-dicarboxylic acid 0
                                            dihydrodipicolinic acid + 0
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