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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:tiquizium bromide
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Accession:CHEBI:32232 term browser browse the term
Definition:A organic bromide salt of tiquizium. It is an antispasmodic drug used for the treatment of convulsion and hypermobility in gastritis, gastric ulcer, duodenal ulcer, enteritis, irritable bowel syndrome, gallbladder disease, biliary tract disease and urolithiasis.
Synonyms:exact_synonym: (5R,9aR)-3-[di(thiophen-2-yl)methylidene]-5-methyloctahydro-2H-quinolizinium bromide
 related_synonym: (5R,9aR)-3-[di(thiophen-2-yl)methylidene]-5-methyloctahydro-2H-quinolizin-5-ium bromide;   3-(di(2-thienyl)methylene)-5-methyldecahydroquinolizinium bromide;   3-(di-2-thienylmethylene)-5-methyl-trans-quinolizidinium bromide;   Advaston;   Aspora;   Breiful;   Formula=C19H24NS2.Br;   Gastirol;   HSR 902;   InChI=1S/C19H24NS2.BrH/c1-20-11-3-2-6-16(20)10-9-15(14-20)19(17-7-4-12-21-17)18-8-5-13-22-18;/h4-5,7-8,12-13,16H,2-3,6,9-11,14H2,1H3;1H/q+1;/p-1/t16-,20-;/m1./s1;   InChIKey=VKBNGRDAHSELMQ-KYSFMIDTSA-M;   SMILES=C(=C1C[N@+]2(C)[C@@](CC1)(CCCC2)[H])(C3=CC=CS3)C4=CC=CS4.[Br-];   Thiameron;   Thiaton;   Thiwan;   Tiapaston;   bromure de tiquizium;   bromuro de tiquizio;   tiquizii bromidum;   trans-3-(di-2-thienylmethylene)octahydro-5-methyl-2H-quinolizinium bromide
 xref: CAS:71731-58-3;   Drug_Central:2678;   KEGG:D01875
 xref_mesh: MESH:C030950
 xref: PMID:10475017;   PMID:11855677;   PMID:2881461;   PMID:2895053;   PMID:2895054;   PMID:3656779;   PMID:4090525;   PMID:6120131;   PMID:6277751;   PMID:6631675;   PMID:6677720;   PMID:7262709;   PMID:7302972;   PMID:8839659


show annotations for term's descendants           Sort by:
tiquizium bromide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO thiaton results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Mpo myeloperoxidase multiple interactions EXP thiaton inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:11855677 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP thiaton inhibits the reaction [Indomethacin results in increased activity of NOS2 protein] CTD PMID:11855677 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19832
    role 19808
      application 19651
        pharmaceutical 19492
          drug 19492
            anti-ulcer drug 1188
              tiquizium bromide 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19832
    subatomic particle 19830
      composite particle 19830
        hadron 19830
          baryon 19830
            nucleon 19830
              atomic nucleus 19830
                atom 19830
                  main group element atom 19780
                    main group molecular entity 19780
                      s-block molecular entity 19618
                        hydrogen molecular entity 19605
                          hydrides 19104
                            inorganic hydride 18115
                              pnictogen hydride 18104
                                nitrogen hydride 18011
                                  ammonium 8309
                                    ammonium ion derivative 8304
                                      ammonium compound 5193
                                        organoammonium salt 655
                                          quaternary ammonium salt 537
                                            tiquizium bromide 3
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