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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:quaternary ammonium salt
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Accession:CHEBI:35273 term browser browse the term
Definition:Derivatives of ammonium compounds, (NH4(+))Y(-), in which all four of the hydrogens bonded to nitrogen have been replaced with univalent (usually organyl) groups.
Synonyms:exact_synonym: quaternary ammonium compounds
 related_synonym: quaternary ammonium compound;   quaternary ammonium salts
 alt_id: CHEBI:26468;   CHEBI:35268

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1,1-dimethyl-4-phenylpiperazinium iodide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrna2 cholinergic receptor nicotinic alpha 2 subunit multiple interactions ISO Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNB4 protein binds to CHRNA2 protein] CTD PMID:9454827 NCBI chr15:42,808,897...42,825,179
Ensembl chr15:42,808,897...42,825,179 		JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit multiple interactions ISO Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNB4 protein binds to CHRNA3 protein] CTD PMID:9454827 NCBI chr 8:59,594,007...59,607,122
Ensembl chr 8:59,592,403...59,607,275 		JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions ISO Dimethylphenylpiperazinium Iodide inhibits the reaction [epibatidine binds to [CHRNA4 protein binds to CHRNB2 protein]]; Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]; Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNB4 protein binds to CHRNA4 protein] CTD PMID:9454827 PMID:14645658 NCBI chr 3:176,533,182...176,547,965
Ensembl chr 3:176,527,516...176,548,208 		JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit multiple interactions
increases response to substance
increases activity		 ISO Dimethylphenylpiperazinium Iodide inhibits the reaction [Bungarotoxins binds to CHRNA7 protein]
CHRNA7 protein mutant form results in increased susceptibility to Dimethylphenylpiperazinium Iodide
Dimethylphenylpiperazinium Iodide results in increased activity of CHRNA7 protein		 CTD PMID:10082212 PMID:10216184 NCBI chr 1:123,897,341...124,039,263
Ensembl chr 1:123,899,657...124,039,196 		JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions ISO Dimethylphenylpiperazinium Iodide inhibits the reaction [epibatidine binds to [CHRNA4 protein binds to CHRNB2 protein]]; Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNA4 protein binds to CHRNB2 protein] CTD PMID:14645658 NCBI chr 2:189,088,570...189,096,785
Ensembl chr 2:189,088,570...189,096,785 		JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit multiple interactions ISO Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNB4 protein binds to CHRNA2 protein]; Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNB4 protein binds to CHRNA3 protein]; Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNB4 protein binds to CHRNA4 protein] CTD PMID:9454827 NCBI chr 8:59,610,489...59,629,073
Ensembl chr 8:59,609,693...59,629,133 		JBrowse link
G Tnf tumor necrosis factor increases activity EXP TNF results in increased activity of Dimethylphenylpiperazinium Iodide CTD PMID:15086448 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
ambenonium chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein affects cleavage EXP Ambenonium Chloride affects the cleavage of APP protein CTD PMID:11099780 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858 		JBrowse link
benzalkonium chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aacs acetoacetyl-CoA synthetase increases expression ISO Benzalkonium Compounds results in increased expression of AACS mRNA CTD PMID:31199489 NCBI chr12:36,512,393...36,555,694
Ensembl chr12:36,512,393...36,555,694 		JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 decreases expression ISO Benzalkonium Compounds results in decreased expression of ABCA1 mRNA CTD PMID:26919959 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015 		JBrowse link
G Abca12 ATP binding cassette subfamily A member 12 increases expression ISO Benzalkonium Compounds results in increased expression of ABCA12 mRNA CTD PMID:25377654 NCBI chr 9:78,521,477...78,693,421
Ensembl chr 9:78,522,464...78,693,028 		JBrowse link
G Abca6 ATP binding cassette subfamily A member 6 decreases expression ISO Benzalkonium Compounds results in decreased expression of ABCA6 mRNA CTD PMID:20713136 NCBI chr10:98,477,716...98,546,699
Ensembl chr10:98,478,067...98,544,447 		JBrowse link
G Acod1 aconitate decarboxylase 1 increases expression ISO Benzalkonium Compounds results in increased expression of ACOD1 mRNA CTD PMID:30171875 NCBI chr15:93,612,968...93,622,322
Ensembl chr15:93,612,971...93,622,358 		JBrowse link
G Acp6 acid phosphatase 6, lysophosphatidic increases expression ISO Benzalkonium Compounds results in increased expression of ACP6 mRNA CTD PMID:31199489 NCBI chr 2:199,284,177...199,305,793
Ensembl chr 2:199,283,909...199,305,799 		JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 increases expression ISO Benzalkonium Compounds results in increased expression of ACSL4 mRNA CTD PMID:31199489 NCBI chr  X:113,596,247...113,660,024
Ensembl chr  X:113,596,239...113,659,944 		JBrowse link
G Ada adenosine deaminase increases expression ISO Benzalkonium Compounds results in increased expression of ADA mRNA CTD PMID:30171875 NCBI chr 3:160,115,840...160,139,947
Ensembl chr 3:160,115,842...160,139,947 		JBrowse link
G Adh1 alcohol dehydrogenase 1 (class I) decreases expression ISO Benzalkonium Compounds results in decreased expression of ADH1 mRNA CTD PMID:31199489 NCBI chr 2:243,550,655...243,562,243
Ensembl chr 2:243,550,627...243,687,857 		JBrowse link
G Adora1 adenosine A1 receptor decreases expression ISO Benzalkonium Compounds results in decreased expression of ADORA1 mRNA CTD PMID:30171875 NCBI chr13:51,042,111...51,076,913
Ensembl chr13:51,042,248...51,076,852 		JBrowse link
G Adra2a adrenoceptor alpha 2A multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of ADRA2A mRNA CTD PMID:30171875 NCBI chr 1:274,766,283...274,769,083
Ensembl chr 1:274,766,283...274,769,081 		JBrowse link
G Agtr2 angiotensin II receptor, type 2 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of AGTR2 mRNA CTD PMID:30171875 NCBI chr  X:119,389,480...119,393,845
Ensembl chr  X:119,390,013...119,393,842 		JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases expression ISO Benzalkonium Compounds results in increased expression of AKR1B10 mRNA CTD PMID:30806763 NCBI chr 4:61,813,265...61,830,371
Ensembl chr 4:61,771,970...61,828,657 		JBrowse link
G Alb albumin decreases expression ISO Benzalkonium Compounds results in decreased expression of ALB mRNA CTD PMID:31199489 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863 		JBrowse link
G Apoa1 apolipoprotein A1 decreases expression ISO Benzalkonium Compounds results in decreased expression of APOA1 mRNA CTD PMID:31199489 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875 		JBrowse link
G Apoa2 apolipoprotein A2 decreases expression ISO Benzalkonium Compounds results in decreased expression of APOA2 mRNA CTD PMID:31199489 NCBI chr13:89,596,872...89,598,805
Ensembl chr13:89,597,138...89,598,802 		JBrowse link
G Apoc1 apolipoprotein C1 decreases expression ISO Benzalkonium Compounds results in decreased expression of APOC1 mRNA CTD PMID:31199489 NCBI chr 1:80,606,638...80,609,921
Ensembl chr 1:80,606,638...80,609,921 		JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) increases expression ISO Benzalkonium Compounds results in increased expression of AQP3 mRNA CTD PMID:30171875 NCBI chr 5:57,423,735...57,429,252
Ensembl chr 5:57,423,734...57,429,245 		JBrowse link
G Areg amphiregulin increases expression ISO Benzalkonium Compounds results in increased expression of AREG mRNA CTD PMID:30171875 NCBI chr14:18,521,921...18,531,179
Ensembl chr14:18,521,930...18,531,179 		JBrowse link
G Arg2 arginase 2 increases expression ISO Benzalkonium Compounds results in increased expression of ARG2 mRNA CTD PMID:30171875 NCBI chr 6:102,311,097...102,338,406
Ensembl chr 6:102,311,116...102,338,520 		JBrowse link
G Art3 ADP-ribosyltransferase 3 decreases expression ISO Benzalkonium Compounds results in decreased expression of ART3 mRNA CTD PMID:31199489 NCBI chr14:17,143,037...17,225,389
Ensembl chr14:17,143,040...17,225,389 		JBrowse link
G Atf4 activating transcription factor 4 decreases expression ISO Benzalkonium Compounds results in decreased expression of ATF4 mRNA CTD PMID:28236482 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772 		JBrowse link
G Atp5f1e ATP synthase F1 subunit epsilon decreases expression ISO Benzalkonium Compounds results in decreased expression of ATP5E mRNA CTD PMID:31199489 NCBI chr 3:172,563,105...172,566,007
Ensembl chr 3:172,563,105...172,566,010 		JBrowse link
G Atp5mg ATP synthase membrane subunit g decreases expression ISO Benzalkonium Compounds results in decreased expression of ATP5L mRNA CTD PMID:31199489 NCBI chr 8:49,220,441...49,227,273
Ensembl chr 8:49,220,443...49,227,273 		JBrowse link
G B3galt4 Beta-1,3-galactosyltransferase 4 affects response to substance ISO B3GALT4 SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr20:5,446,104...5,447,679
Ensembl chr20:5,446,104...5,447,673 		JBrowse link
G Bambi BMP and activin membrane-bound inhibitor increases expression ISO Benzalkonium Compounds results in increased expression of BAMBI mRNA CTD PMID:20146380 NCBI chr17:56,905,419...56,909,675
Ensembl chr17:56,905,112...56,909,992 		JBrowse link
G Bcl3 BCL3, transcription coactivator increases expression ISO Benzalkonium Compounds results in increased expression of BCL3 mRNA CTD PMID:30171875 NCBI chr 1:80,730,758...80,745,273
Ensembl chr 1:80,730,499...80,744,831 		JBrowse link
G Btc betacellulin decreases expression ISO Benzalkonium Compounds results in decreased expression of BTC mRNA CTD PMID:30171875 NCBI chr14:18,231,854...18,270,621
Ensembl chr14:18,231,860...18,272,484 		JBrowse link
G C1s complement C1s multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of C1S2 mRNA CTD PMID:30171875 NCBI chr 4:157,143,592...157,155,592
Ensembl chr 4:157,143,592...157,155,609 		JBrowse link
G C3 complement C3 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of C3 mRNA CTD PMID:30171875 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167 		JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions		 ISO Benzalkonium Compounds analog results in increased cleavage of CASP3 protein
benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [Benzalkonium Compounds analog results in increased cleavage of CASP3 protein]		 CTD PMID:31982400 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204 		JBrowse link
G Casp8 caspase 8 decreases expression ISO Benzalkonium Compounds results in decreased expression of CASP8 mRNA CTD PMID:28236482 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106 		JBrowse link
G Ccl11 C-C motif chemokine ligand 11 increases expression ISO Benzalkonium Compounds results in increased expression of CCL11 protein CTD PMID:30517752 NCBI chr10:69,434,965...69,439,566
Ensembl chr10:69,434,941...69,439,575 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression
increases secretion		 ISO Benzalkonium Compounds results in increased expression of CCL2 mRNA; Benzalkonium Compounds results in increased expression of CCL2 protein
Benzalkonium Compounds results in increased secretion of CCL2 protein		 CTD PMID:30171875 PMID:30517752 PMID:31707104 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 increases expression ISO Benzalkonium Compounds results in increased expression of CCL20 mRNA CTD PMID:30806763 NCBI chr 9:88,918,359...88,921,017
Ensembl chr 9:88,918,433...88,921,001 		JBrowse link
G Ccl24 C-C motif chemokine ligand 24 decreases expression ISO Benzalkonium Compounds results in decreased expression of CCL24 mRNA CTD PMID:30171875 NCBI chr12:24,131,529...24,152,626
Ensembl chr12:24,148,567...24,152,625 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression
multiple interactions		 ISO Benzalkonium Compounds results in increased expression of CCL3 protein
[IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of CCL3 protein		 CTD PMID:30517752 PMID:31158415 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 decreases expression
multiple interactions
increases expression		 ISO Benzalkonium Compounds results in decreased expression of CCL4 mRNA; Benzalkonium Compounds results in decreased expression of CCL4 protein
[IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of CCL4 protein
Benzalkonium Compounds results in increased expression of CCL4 protein		 CTD PMID:18353026 PMID:20713136 PMID:30517752 PMID:31158415 NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression ISO Benzalkonium Compounds results in increased expression of CCL5 protein CTD PMID:30517752 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315 		JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases expression ISO Benzalkonium Compounds results in increased expression of CCL7 mRNA; Benzalkonium Compounds results in increased expression of CCL7 protein CTD PMID:30171875 PMID:30517752 NCBI chr10:69,423,083...69,424,933
Ensembl chr10:69,423,086...69,424,979 		JBrowse link
G Ccn2 cellular communication network factor 2 decreases expression ISO Benzalkonium Compounds results in decreased expression of CCN2 mRNA CTD PMID:25377654 NCBI chr 1:21,851,657...21,854,773
Ensembl chr 1:21,851,660...21,854,773 		JBrowse link
G Ccn3 cellular communication network factor 3 increases expression ISO Benzalkonium Compounds results in increased expression of CCN3 mRNA CTD PMID:30171875 NCBI chr 7:94,375,134...94,382,154
Ensembl chr 7:94,375,020...94,383,024 		JBrowse link
G Ccr4 C-C motif chemokine receptor 4 decreases expression ISO Benzalkonium Compounds results in decreased expression of CCR4 mRNA CTD PMID:30171875 NCBI chr 8:122,530,152...122,535,959
Ensembl chr 8:122,530,624...122,532,070 		JBrowse link
G Ccr5 C-C motif chemokine receptor 5 increases expression ISO Benzalkonium Compounds results in increased expression of CCR5 mRNA CTD PMID:30171875 NCBI chr 8:133,192,398...133,215,599
Ensembl chr 8:133,197,032...133,215,614 		JBrowse link
G Cd177 CD177 molecule multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CD177 mRNA CTD PMID:30171875 NCBI chr 1:82,964,683...82,987,306
Ensembl chr 1:82,964,683...82,987,253 		JBrowse link
G Cd274 CD274 molecule multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CD274 mRNA CTD PMID:30171875 NCBI chr 1:247,519,890...247,539,659
Ensembl chr 1:247,519,939...247,537,943 		JBrowse link
G Cd300c2 CD300C molecule 2 increases expression ISO Benzalkonium Compounds results in increased expression of CD300C2 mRNA CTD PMID:30171875 NCBI chr10:104,997,205...104,999,942
Ensembl chr10:104,975,877...105,051,965 		JBrowse link
G Cfap61 cilia and flagella associated protein 61 increases expression ISO Benzalkonium Compounds results in increased expression of CFAP61 mRNA CTD PMID:31199489 NCBI chr 3:140,141,768...140,421,840 JBrowse link
G Cfd complement factor D decreases expression ISO Benzalkonium Compounds results in decreased expression of CFD mRNA CTD PMID:30171875 NCBI chr 7:12,634,216...12,635,939
Ensembl chr 7:12,634,216...12,635,943 		JBrowse link
G Chi3l1 chitinase 3 like 1 increases expression ISO Benzalkonium Compounds results in increased expression of CHIL1 mRNA CTD PMID:30171875 NCBI chr13:51,022,844...51,030,797
Ensembl chr13:51,022,681...51,030,802 		JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit decreases expression ISO Benzalkonium Compounds results in decreased expression of CHRNB4 mRNA CTD PMID:30171875 NCBI chr 8:59,610,489...59,629,073
Ensembl chr 8:59,609,693...59,629,133 		JBrowse link
G Clcf1 cardiotrophin-like cytokine factor 1 increases expression ISO Benzalkonium Compounds results in increased expression of CLCF1 mRNA CTD PMID:30171875 NCBI chr 1:219,468,866...219,472,445
Ensembl chr 1:219,468,675...219,472,654 		JBrowse link
G Cnfn cornifelin increases expression ISO Benzalkonium Compounds results in increased expression of CNFN mRNA; Benzalkonium Compounds results in increased expression of CNFN protein CTD PMID:25377654 NCBI chr 1:82,234,032...82,236,602
Ensembl chr 1:82,234,032...82,236,179 		JBrowse link
G Csf1 colony stimulating factor 1 increases expression ISO Benzalkonium Compounds results in increased expression of CSF1 protein CTD PMID:30517752 NCBI chr 2:210,522,370...210,550,546
Ensembl chr 2:210,522,375...210,550,560 		JBrowse link
G Csf2 colony stimulating factor 2 increases expression ISO Benzalkonium Compounds results in increased expression of CSF2 protein CTD PMID:30517752 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070 		JBrowse link
G Csf3 colony stimulating factor 3 increases expression ISO Benzalkonium Compounds results in increased expression of CSF3 protein CTD PMID:30517752 NCBI chr10:86,616,785...86,619,160
Ensembl chr10:86,616,785...86,619,157 		JBrowse link
G Ctps1 CTP synthase 1 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CTPS mRNA CTD PMID:30171875 NCBI chr 5:139,475,934...139,505,065
Ensembl chr 5:139,475,934...139,505,065 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression
multiple interactions		 ISO Benzalkonium Compounds results in increased expression of CXCL10 mRNA; Benzalkonium Compounds results in increased expression of CXCL10 protein
[IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of CXCL10 protein		 CTD PMID:23445166 PMID:30517752 PMID:31158415 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression
multiple interactions		 ISO Benzalkonium Compounds results in increased expression of CXCL2 mRNA; Benzalkonium Compounds results in increased expression of CXCL2 protein
[IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of CXCL2 protein		 CTD PMID:30171875 PMID:30517752 PMID:31158415 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions
increases expression		 ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CXCL3 mRNA
Benzalkonium Compounds results in increased expression of CXCL1 protein; Benzalkonium Compounds results in increased expression of CXCL3 mRNA		 CTD PMID:30171875 PMID:30517752 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595 		JBrowse link
G Cxcr1 C-X-C motif chemokine receptor 1 increases expression ISO Benzalkonium Compounds results in increased expression of CXCR1 mRNA CTD PMID:30806763 NCBI chr 9:81,466,430...81,469,299
Ensembl chr 9:81,466,332...81,469,274 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression ISO Benzalkonium Compounds results in increased expression of CXCR4 mRNA CTD PMID:20713136 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases expression
increases expression		 ISO Benzalkonium Compounds results in decreased expression of CYP1A1 mRNA
Benzalkonium Compounds results in increased expression of CYP1A1 mRNA		 CTD PMID:20713136 PMID:30806763 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147 		JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 decreases expression ISO Benzalkonium Compounds results in decreased expression of CYP27A1 mRNA CTD PMID:20713136 NCBI chr 9:81,968,285...81,998,213
Ensembl chr 9:81,968,332...81,998,169 		JBrowse link
G Cyp51 cytochrome P450, family 51 increases expression ISO Benzalkonium Compounds results in increased expression of CYP51 mRNA CTD PMID:31199489 NCBI chr 4:27,175,564...27,194,018
Ensembl chr 4:27,175,243...27,194,018 		JBrowse link
G Dhcr24 24-dehydrocholesterol reductase increases expression ISO Benzalkonium Compounds results in increased expression of DHCR24 mRNA CTD PMID:31199489 NCBI chr 5:126,164,708...126,188,926
Ensembl chr 5:126,164,674...126,191,206 		JBrowse link
G Dhcr7 7-dehydrocholesterol reductase decreases activity
increases expression		 ISO Benzalkonium Compounds results in decreased activity of DHCR7 protein
Benzalkonium Compounds results in increased expression of DHCR7 mRNA		 CTD PMID:26919959 NCBI chr 1:217,018,916...217,034,890
Ensembl chr 1:217,018,916...217,034,904 		JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases activity ISO Benzalkonium Compounds results in decreased activity of DIO1 protein CTD PMID:30561685 NCBI chr 5:126,894,837...126,911,532
Ensembl chr 5:126,895,286...126,911,520 		JBrowse link
G Dio2 iodothyronine deiodinase 2 decreases activity ISO Benzalkonium Compounds results in decreased activity of DIO2 protein CTD PMID:30561685 NCBI chr 6:114,475,156...114,489,443
Ensembl chr 6:114,476,142...114,476,723 		JBrowse link
G Dio3 iodothyronine deiodinase 3 decreases activity ISO Benzalkonium Compounds results in decreased activity of DIO3 protein CTD PMID:30561685 NCBI chr 6:134,627,278...134,629,139
Ensembl chr 6:134,627,278...134,629,138 		JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 decreases expression ISO Benzalkonium Compounds results in decreased expression of DLK1 mRNA CTD PMID:31199489 NCBI chr 6:133,576,513...133,583,751
Ensembl chr 6:133,552,821...133,583,751 		JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO Benzalkonium Compounds results in increased expression of DUSP1 mRNA CTD PMID:30806763 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418 		JBrowse link
G Ebp EBP, cholestenol delta-isomerase increases expression ISO Benzalkonium Compounds results in increased expression of EBP mRNA CTD PMID:26919959 NCBI chr  X:15,049,394...15,055,782
Ensembl chr  X:15,049,462...15,055,781 		JBrowse link
G Egf epidermal growth factor decreases expression ISO Benzalkonium Compounds results in decreased expression of EGF mRNA CTD PMID:30171875 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Egr1 early growth response 1 increases expression ISO Benzalkonium Compounds results in increased expression of EGR1 mRNA CTD PMID:25377654 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429 		JBrowse link
G Elf3 E74 like ETS transcription factor 3 increases expression ISO Benzalkonium Compounds results in increased expression of ELF3 mRNA CTD PMID:30171875 NCBI chr13:52,083,873...52,088,798
Ensembl chr13:52,083,859...52,088,780 		JBrowse link
G Elovl1 ELOVL fatty acid elongase 1 increases expression ISO Benzalkonium Compounds results in increased expression of ELOVL1 mRNA CTD PMID:29155129 NCBI chr 5:137,255,868...137,260,486
Ensembl chr 5:137,255,908...137,260,483 		JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 increases expression ISO Benzalkonium Compounds results in increased expression of ELOVL6 mRNA CTD PMID:31199489 NCBI chr 2:234,187,490...234,296,124
Ensembl chr 2:234,189,105...234,296,145
Ensembl chr 2:234,189,105...234,296,145 		JBrowse link
G Endou endonuclease, poly(U)-specific increases expression ISO Benzalkonium Compounds results in increased expression of ENDOU mRNA CTD PMID:30171875 NCBI chr 7:139,202,342...139,223,022
Ensembl chr 7:139,201,054...139,223,116 		JBrowse link
G Eno1 enolase 1 decreases expression ISO Benzalkonium Compounds results in decreased expression of ENO1 mRNA CTD PMID:31199489 NCBI chr 5:167,288,223...167,299,610
Ensembl chr 5:167,288,223...167,299,609 		JBrowse link
G Etnk1 ethanolamine kinase 1 increases expression ISO Benzalkonium Compounds results in increased expression of ETNK1 mRNA CTD PMID:31199489 NCBI chr 4:177,402,904...177,447,047
Ensembl chr 4:177,402,904...177,447,028 		JBrowse link
G Exo1 exonuclease 1 increases expression ISO Benzalkonium Compounds results in increased expression of EXO1 mRNA CTD PMID:30171875 NCBI chr13:93,936,989...93,962,749
Ensembl chr13:93,939,022...93,960,342 		JBrowse link
G Ezr ezrin increases expression ISO Benzalkonium Compounds results in increased expression of EZR mRNA; Benzalkonium Compounds results in increased expression of EZR protein CTD PMID:29893927 NCBI chr 1:47,287,872...47,331,412
Ensembl chr 1:47,287,874...47,331,412 		JBrowse link
G Fam83a family with sequence similarity 83, member A increases expression ISO Benzalkonium Compounds results in increased expression of FAM83A mRNA CTD PMID:30171875 NCBI chr 7:97,855,773...97,880,227
Ensembl chr 7:97,855,636...97,881,955 		JBrowse link
G Fgf2 fibroblast growth factor 2 affects response to substance ISO FGF2 SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27206134 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681 		JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase increases expression ISO Benzalkonium Compounds results in increased expression of FGR mRNA CTD PMID:30171875 NCBI chr 5:151,172,189...151,199,746
Ensembl chr 5:151,172,206...151,199,745 		JBrowse link
G Flg filaggrin increases expression ISO Benzalkonium Compounds results in increased expression of FLG mRNA CTD PMID:30171875 NCBI chr 2:193,565,401...193,574,297 JBrowse link
G Foxc1 forkhead box C1 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of FOXC1 mRNA CTD PMID:30171875 NCBI chr17:33,947,501...33,951,484
Ensembl chr17:33,947,506...33,951,484 		JBrowse link
G Foxn1 forkhead box N1 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of FOXN1 mRNA CTD PMID:30171875 NCBI chr10:65,621,142...65,634,666
Ensembl chr10:65,621,257...65,634,666 		JBrowse link
G Foxp3 forkhead box P3 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of FOXP3 mRNA CTD PMID:30171875 NCBI chr  X:15,753,175...15,768,648
Ensembl chr  X:15,753,175...15,768,522 		JBrowse link
G Gata3 GATA binding protein 3 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of GATA3 mRNA CTD PMID:30171875 NCBI chr17:72,419,752...72,452,043
Ensembl chr17:72,429,618...72,450,681 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO Benzalkonium Compounds results in increased expression of GCLC mRNA CTD PMID:30806763 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Benzalkonium Compounds results in increased expression of GCLM mRNA CTD PMID:30806763 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874 		JBrowse link
G Gpx2 glutathione peroxidase 2 increases expression ISO Benzalkonium Compounds results in increased expression of GPX2 mRNA CTD PMID:30171875 NCBI chr 6:99,839,960...99,843,245
Ensembl chr 6:99,839,960...99,843,245 		JBrowse link
G Hbegf heparin-binding EGF-like growth factor increases expression ISO Benzalkonium Compounds results in increased expression of HBEGF mRNA CTD PMID:30171875 NCBI chr18:29,330,302...29,340,185
Ensembl chr18:29,329,764...29,340,403 		JBrowse link
G Hck HCK proto-oncogene, Src family tyrosine kinase multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of HCK mRNA CTD PMID:30171875 NCBI chr 3:148,579,917...148,623,026
Ensembl chr 3:148,579,920...148,623,033 		JBrowse link
G Hgf hepatocyte growth factor multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of HGF mRNA CTD PMID:30171875 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression ISO Benzalkonium Compounds results in increased expression of HIF1A mRNA CTD PMID:30171875 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase increases expression ISO Benzalkonium Compounds results in increased expression of HMGCR mRNA CTD PMID:26919959 PMID:31199489 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654 		JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 increases expression ISO Benzalkonium Compounds results in increased expression of HMGCS2 mRNA CTD PMID:31199489 NCBI chr 2:200,452,623...200,480,785
Ensembl chr 2:200,452,624...200,479,423 		JBrowse link
G Hoxa7 homeobox A7 decreases expression ISO Benzalkonium Compounds results in decreased expression of HOXA7 mRNA CTD PMID:30171875 NCBI chr 4:82,184,299...82,187,890
Ensembl chr 4:82,183,196...82,186,190 		JBrowse link
G Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 increases expression ISO Benzalkonium Compounds results in increased expression of HSD17B7 mRNA CTD PMID:31199489 NCBI chr13:88,288,116...88,308,019
Ensembl chr13:88,288,046...88,307,988 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 decreases expression ISO Benzalkonium Compounds results in decreased expression of HSPA5 mRNA CTD PMID:28236482 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762 		JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO Benzalkonium Compounds results in increased expression of ICAM1 mRNA; Benzalkonium Compounds results in increased expression of ICAM1 protein CTD PMID:21742781 PMID:30806763 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059 		JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 increases expression ISO Benzalkonium Compounds results in increased expression of IDI1 mRNA CTD PMID:31199489 NCBI chr17:57,976,266...57,984,036
Ensembl chr17:57,976,268...57,984,036 		JBrowse link
G Ifng interferon gamma increases expression ISO Benzalkonium Compounds results in increased expression of IFNG protein CTD PMID:30517752 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419 		JBrowse link
G Il10 interleukin 10 multiple interactions
increases expression		 ISO Benzalkonium Compounds results in increased expression of and results in decreased secretion of IL10 protein
[IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in decreased expression of IL10 protein
Benzalkonium Compounds results in increased expression of IL10 protein		 CTD PMID:29953848 PMID:30517752 PMID:31158415 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392 		JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 increases expression ISO Benzalkonium Compounds results in increased expression of IL13RA2 mRNA CTD PMID:30171875 NCBI chr  X:118,443,955...118,514,716
Ensembl chr  X:118,443,823...118,513,061 		JBrowse link
G Il15 interleukin 15 increases expression ISO Benzalkonium Compounds results in increased expression of IL15 protein CTD PMID:30517752 NCBI chr19:23,542,606...23,624,366
Ensembl chr19:23,542,889...23,554,594 		JBrowse link
G Il17f interleukin 17F increases expression ISO Benzalkonium Compounds results in increased expression of IL17F mRNA CTD PMID:23445166 NCBI chr 9:26,885,702...26,897,219
Ensembl chr 9:26,885,708...26,897,219 		JBrowse link
G Il18 interleukin 18 increases expression ISO Benzalkonium Compounds results in increased expression of IL18 protein
Benzalkonium Compounds results in increased expression of IL18 mRNA		 CTD PMID:30517752 PMID:30806763 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299 		JBrowse link
G Il1a interleukin 1 alpha increases secretion
multiple interactions
increases expression		 ISO Benzalkonium Compounds results in increased secretion of IL1A protein
[IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of IL1A protein
Benzalkonium Compounds results in increased expression of IL1A protein
Benzalkonium Compounds results in increased expression of IL1A mRNA; Benzalkonium Compounds results in increased expression of IL1A protein		 CTD PMID:8006454 PMID:12781210 PMID:25290854 PMID:30240708 PMID:30517752 PMID:31158415 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086 		JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions		 ISO Benzalkonium Compounds results in increased expression of IL1B protein
[IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of IL1B protein		 CTD PMID:29953848 PMID:30517752 PMID:31158415 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726 		JBrowse link
G Il1f10 interleukin 1 family member 10 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of IL1F10 mRNA CTD PMID:30171875 NCBI chr 3:1,408,560...1,416,601
Ensembl chr 3:1,413,671...1,416,599 		JBrowse link
G Il23a interleukin 23 subunit alpha increases expression ISO Benzalkonium Compounds results in increased expression of IL23A mRNA CTD PMID:30171875 NCBI chr 7:2,710,609...2,712,723
Ensembl chr 7:2,710,609...2,712,723 		JBrowse link
G Il27 interleukin 27 increases expression ISO Benzalkonium Compounds results in increased expression of IL27 protein CTD PMID:30517752 NCBI chr 1:198,003,615...198,010,112
Ensembl chr 1:198,003,683...198,008,893 		JBrowse link
G Il3 interleukin 3 increases expression ISO Benzalkonium Compounds results in increased expression of IL3 protein CTD PMID:30517752 NCBI chr10:39,620,535...39,622,973
Ensembl chr10:39,620,563...39,622,973 		JBrowse link
G Il31 interleukin 31 increases expression ISO Benzalkonium Compounds results in increased expression of IL31 protein CTD PMID:30517752 NCBI chr12:38,527,575...38,538,086 JBrowse link
G Il31ra interleukin 31 receptor A decreases expression ISO Benzalkonium Compounds results in decreased expression of IL31RA mRNA CTD PMID:30171875 NCBI chr 2:44,333,347...44,408,005
Ensembl chr 2:44,336,006...44,394,709 		JBrowse link
G Il34 interleukin 34 decreases expression ISO Benzalkonium Compounds results in decreased expression of IL34 mRNA CTD PMID:30171875 NCBI chr19:40,855,537...40,905,007
Ensembl chr19:40,855,433...40,904,121 		JBrowse link
G Il36a interleukin 36, alpha increases expression ISO Benzalkonium Compounds results in increased expression of IL36A mRNA CTD PMID:30171875 NCBI chr 3:1,330,790...1,335,811
Ensembl chr 3:1,331,226...1,335,775 		JBrowse link
G Il36b interleukin 36, beta increases expression ISO Benzalkonium Compounds results in increased expression of IL36B mRNA CTD PMID:30171875 NCBI chr 3:1,366,123...1,464,851
Ensembl chr 3:1,366,119...1,371,626 		JBrowse link
G Il36g interleukin 36, gamma increases expression ISO Benzalkonium Compounds results in increased expression of IL36G mRNA CTD PMID:30171875 NCBI chr 3:1,285,658...1,291,836
Ensembl chr 3:1,285,664...1,291,865 		JBrowse link
G Il4 interleukin 4 increases expression
multiple interactions		 ISO Benzalkonium Compounds results in increased expression of IL4 protein
[IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in decreased expression of IL4 protein		 CTD PMID:30517752 PMID:31158415 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531 		JBrowse link
G Il5 interleukin 5 increases expression ISO Benzalkonium Compounds results in increased expression of IL5 protein CTD PMID:30517752 NCBI chr10:39,066,716...39,069,587
Ensembl chr10:39,066,716...39,069,587 		JBrowse link
G Il6 interleukin 6 increases secretion
multiple interactions
affects response to substance
increases expression		 ISO Benzalkonium Compounds results in increased secretion of IL6 protein
[IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of ADRA2A mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of AGTR2 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of C1S2 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of C3 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CD177 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CD274 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CTPS mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CXCL3 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of CXCL5 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of FOXC1 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of FOXN1 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of FOXP3 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of GATA3 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of GSDMA3 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of HCK mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of HGF mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of IGHA mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of IL1F10 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRT2 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP14 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP16-3 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP19-2 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP19-5 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP19-9B mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP6-1 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP6-2 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of LTB mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MMP25 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MMP9 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MRGPRA2B mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MSX2 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MYLK3 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of NRG2 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of PDCD1 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of PROKR2 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of PTX3 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of REG1 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of REG3G mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of RYR1 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of SAA3 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of SERPINB13 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of SIGLECE mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of SOX21 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of SRMS mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of ST14 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TFAP2B mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TNFRSF13C mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TNFRSF26 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TNFSF8 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TSLP mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of VTCN1 mRNA; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of IL6 protein
Benzalkonium Compounds results in increased expression of IL6 mRNA; Benzalkonium Compounds results in increased expression of IL6 protein
Benzalkonium Compounds results in increased expression of and results in increased secretion of IL6 protein		 CTD PMID:17763283 PMID:28214551 PMID:29953848 PMID:30171875 PMID:30517752 PMID:31158415 PMID:31707104 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807 		JBrowse link
G Il6r interleukin 6 receptor multiple interactions
increases response to substance		 ISO [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in decreased expression of IL10 protein; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in decreased expression of IL4 protein; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of CCL3 protein; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of CCL4 protein; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of CXCL10 protein; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of CXCL2 protein; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of IL1A protein; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of IL1B protein; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of IL22 protein; [IL6RA gene mutant form results in increased susceptibility to Benzalkonium Compounds] which results in increased expression of IL6 protein CTD PMID:31158415 NCBI chr 2:189,196,180...189,255,987
Ensembl chr 2:189,205,701...189,254,628 		JBrowse link
G Il7r interleukin 7 receptor increases expression ISO Benzalkonium Compounds results in increased expression of IL7R mRNA CTD PMID:20713136
G Inhba inhibin subunit beta A increases expression ISO Benzalkonium Compounds results in increased expression of INHBA mRNA CTD PMID:30171875 NCBI chr17:51,894,869...51,919,998
Ensembl chr17:51,898,217...51,912,496 		JBrowse link
G Insig1 insulin induced gene 1 increases expression ISO Benzalkonium Compounds results in increased expression of INSIG1 mRNA CTD PMID:31199489 NCBI chr 4:342,302...350,515
Ensembl chr 4:342,302...350,515 		JBrowse link
G Isl1 ISL LIM homeobox 1 decreases expression ISO Benzalkonium Compounds results in decreased expression of ISL1 mRNA CTD PMID:30171875 NCBI chr 2:48,488,911...48,501,217
Ensembl chr 2:48,487,736...48,501,436 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Benzalkonium Compounds results in decreased activity of KCNH2 protein CTD PMID:24052561 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253 		JBrowse link
G Kdm8 lysine demethylase 8 decreases expression ISO Benzalkonium Compounds results in decreased expression of KDM8 mRNA CTD PMID:31199489 NCBI chr 1:196,838,460...196,854,192
Ensembl chr 1:196,839,321...196,854,180 		JBrowse link
G Klk8 kallikrein related-peptidase 8 increases expression ISO Benzalkonium Compounds results in increased expression of KLK8 mRNA CTD PMID:30171875 NCBI chr 1:99,735,168...99,742,011
Ensembl chr 1:99,734,993...99,742,009 		JBrowse link
G Krt2 keratin 2 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRT2 mRNA CTD PMID:30171875 NCBI chr 7:143,412,858...143,420,463
Ensembl chr 7:143,412,858...143,420,027 		JBrowse link
G Krtap14 keratin associated protein 14 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP14 mRNA CTD PMID:30171875 NCBI chr11:28,776,761...28,777,603
Ensembl chr11:28,776,761...28,777,603 		JBrowse link
G Lce3e late cornified envelope 3E increases expression ISO Benzalkonium Compounds results in increased expression of LCE3C mRNA CTD PMID:30171875 NCBI chr 2:193,275,472...193,276,006
Ensembl chr 2:193,275,507...193,275,803 		JBrowse link
G Ldha lactate dehydrogenase A decreases expression ISO Benzalkonium Compounds results in decreased expression of LDHA mRNA CTD PMID:31199489 NCBI chr 1:102,900,288...102,909,713
Ensembl chr 1:102,900,286...102,909,707 		JBrowse link
G Ldlr low density lipoprotein receptor increases expression ISO Benzalkonium Compounds results in increased expression of LDLR mRNA CTD PMID:31199489 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903 		JBrowse link
G Lif LIF, interleukin 6 family cytokine increases expression ISO Benzalkonium Compounds results in increased expression of LIF protein CTD PMID:30517752 NCBI chr14:84,482,652...84,500,574
Ensembl chr14:84,482,674...84,500,642 		JBrowse link
G LOC102551406 keratin-associated protein 20-2-like multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP6-1 mRNA; [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of KRTAP6-2 mRNA CTD PMID:30171875 NCBI chr11:29,062,404...29,062,650
Ensembl chr11:29,062,404...29,062,586 		JBrowse link
G LOC102552326 late cornified envelope protein 5A-like decreases expression ISO Benzalkonium Compounds results in decreased expression of LCE1M mRNA CTD PMID:30171875 NCBI chr 2:192,959,220...192,961,921
Ensembl chr 2:192,959,887...192,960,294 		JBrowse link
G Loxl1 lysyl oxidase-like 1 decreases expression ISO Benzalkonium Compounds results in decreased expression of LOXL1 mRNA CTD PMID:31199489 NCBI chr 8:63,067,757...63,092,124
Ensembl chr 8:63,067,300...63,092,009 		JBrowse link
G Lst1 leukocyte specific transcript 1 increases expression ISO Benzalkonium Compounds results in increased expression of LST1 mRNA CTD PMID:30171875 NCBI chr20:5,175,213...5,179,352
Ensembl chr20:5,176,016...5,179,263 		JBrowse link
G Ltb lymphotoxin beta multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of LTB mRNA CTD PMID:30171875 NCBI chr20:5,184,631...5,186,476
Ensembl chr20:5,184,515...5,186,503
Ensembl chr20:5,184,515...5,186,503 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 increases phosphorylation ISO Benzalkonium Compounds results in increased phosphorylation of MAPK14 protein CTD PMID:15737199 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137 		JBrowse link
G Mesp2 mesoderm posterior bHLH transcription factor 2 decreases expression ISO Benzalkonium Compounds results in decreased expression of MESP2 mRNA CTD PMID:30171875 NCBI chr 1:141,550,633...141,553,239
Ensembl chr 1:141,550,633...141,553,230 		JBrowse link
G Mif macrophage migration inhibitory factor increases secretion ISO Benzalkonium Compounds results in increased secretion of MIF protein CTD PMID:31707104 NCBI chr20:13,715,219...13,732,980
Ensembl chr20:13,732,198...13,732,859 		JBrowse link
G Mmp10 matrix metallopeptidase 10 increases expression ISO Benzalkonium Compounds results in increased expression of MMP10 mRNA CTD PMID:30806763 NCBI chr 8:5,734,348...5,742,243
Ensembl chr 8:5,734,348...5,742,243 		JBrowse link
G Mmp12 matrix metallopeptidase 12 increases expression ISO Benzalkonium Compounds results in increased expression of MMP12 mRNA CTD PMID:30171875 NCBI chr 8:5,594,717...5,616,494
Ensembl chr 8:5,606,592...5,616,493 		JBrowse link
G Mmp25 matrix metallopeptidase 25 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MMP25 mRNA CTD PMID:30171875 NCBI chr10:12,962,214...12,966,377 JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MMP9 mRNA CTD PMID:30171875 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520 		JBrowse link
G Msmo1 methylsterol monooxygenase 1 increases expression ISO Benzalkonium Compounds results in increased expression of MSMO1 mRNA CTD PMID:31199489 NCBI chr16:26,859,441...26,875,880
Ensembl chr16:26,859,397...26,875,973 		JBrowse link
G Msx2 msh homeobox 2 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MSX2 mRNA CTD PMID:30171875 NCBI chr17:11,683,862...11,689,527
Ensembl chr17:11,683,862...11,689,527 		JBrowse link
G Mt2A metallothionein 2A decreases expression ISO Benzalkonium Compounds results in decreased expression of MT2 mRNA CTD PMID:31199489 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740 		JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase decreases expression ISO Benzalkonium Compounds results in decreased expression of MTHFD2 mRNA CTD PMID:31199489 NCBI chr 4:115,004,433...115,015,965
Ensembl chr 4:115,004,448...115,015,965 		JBrowse link
G Mylk3 myosin light chain kinase 3 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of MYLK3 mRNA CTD PMID:30171875 NCBI chr19:27,388,163...27,442,451
Ensembl chr19:27,404,712...27,441,536 		JBrowse link
G Ndufa4 NDUFA4, mitochondrial complex associated decreases expression ISO Benzalkonium Compounds results in decreased expression of NDUFA4 mRNA CTD PMID:31199489 NCBI chr 4:38,233,680...38,240,848
Ensembl chr 4:38,233,680...38,240,848 		JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 increases expression ISO Benzalkonium Compounds results in increased expression of NR4A2 mRNA CTD PMID:25377654 NCBI chr 3:43,111,258...43,128,391
Ensembl chr 3:43,111,240...43,119,159 		JBrowse link
G Nrg2 neuregulin 2 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of NRG2 mRNA CTD PMID:30171875 NCBI chr18:28,835,391...29,015,552
Ensembl chr18:28,835,417...29,015,552 		JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 affects response to substance ISO NTRK3 SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27206134 NCBI chr 1:139,890,537...140,262,503
Ensembl chr 1:139,890,560...140,262,503 		JBrowse link
G Ocln occludin decreases expression ISO Benzalkonium Compounds results in decreased expression of OCLN protein CTD PMID:29514330 NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218 		JBrowse link
G Odc1 ornithine decarboxylase 1 decreases expression ISO Benzalkonium Compounds results in decreased expression of ODC1 mRNA CTD PMID:31199489 NCBI chr 6:42,852,529...42,859,142
Ensembl chr 6:42,852,683...42,859,927 		JBrowse link
G Odf3l2 outer dense fiber of sperm tails 3-like 2 decreases expression ISO Benzalkonium Compounds results in decreased expression of ODF3L2 mRNA CTD PMID:30171875 NCBI chr 7:12,941,994...12,946,981
Ensembl chr 7:12,941,994...12,946,981 		JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 increases expression ISO Benzalkonium Compounds results in increased expression of OLR1 mRNA CTD PMID:30171875 NCBI chr 4:163,239,853...163,261,937
Ensembl chr 4:163,239,849...163,261,958 		JBrowse link
G Orm1 orosomucoid 1 decreases expression ISO Benzalkonium Compounds results in decreased expression of ORM1 mRNA CTD PMID:30171875 NCBI chr 5:79,179,668...79,182,820
Ensembl chr 5:79,179,417...79,182,820 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions		 ISO Benzalkonium Compounds analog results in increased cleavage of PARP1 protein
benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [Benzalkonium Compounds analog results in increased cleavage of PARP1 protein]		 CTD PMID:31982400 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716 		JBrowse link
G Pbk PDZ binding kinase increases expression ISO Benzalkonium Compounds results in increased expression of PBK mRNA CTD PMID:30171875 NCBI chr15:42,489,253...42,500,377
Ensembl chr15:42,489,377...42,500,395 		JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 decreases expression ISO Benzalkonium Compounds results in decreased expression of PCSK9 mRNA CTD PMID:31199489 NCBI chr 5:126,031,368...126,053,726
Ensembl chr 5:126,031,368...126,053,726 		JBrowse link
G Pdcd1 programmed cell death 1 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of PDCD1 mRNA CTD PMID:30171875 NCBI chr 9:101,305,742...101,319,937
Ensembl chr 9:101,307,764...101,319,845
Ensembl chr 9:101,307,764...101,319,845 		JBrowse link
G Pfdn6 prefoldin subunit 6 affects response to substance ISO PFDN6 SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr20:5,455,974...5,457,448
Ensembl chr20:5,455,974...5,457,444 		JBrowse link
G Pglyrp3 peptidoglycan recognition protein 3 increases expression ISO Benzalkonium Compounds results in increased expression of PGLYRP3 mRNA CTD PMID:30171875 NCBI chr 2:191,903,626...192,264,872
Ensembl chr 2:192,253,629...192,264,840 		JBrowse link
G Pgp phosphoglycolate phosphatase increases expression ISO Benzalkonium Compounds results in increased expression of PGP mRNA CTD PMID:31199489 NCBI chr10:13,836,105...13,838,731
Ensembl chr10:13,836,128...13,838,765 		JBrowse link
G Pla2g5 phospholipase A2, group V decreases expression ISO Benzalkonium Compounds results in decreased expression of PLA2G5 mRNA CTD PMID:30171875 NCBI chr 5:157,247,601...157,268,968
Ensembl chr 5:157,247,781...157,268,903 		JBrowse link
G Plcxd3 phosphatidylinositol-specific phospholipase C, X domain containing 3 increases expression ISO Benzalkonium Compounds results in increased expression of PLCXD3 mRNA CTD PMID:31199489 NCBI chr 2:54,191,538...54,360,780
Ensembl chr 2:54,191,538...54,360,780 		JBrowse link
G Pnpla2 patatin-like phospholipase domain containing 2 decreases expression ISO Benzalkonium Compounds results in decreased expression of PNPLA2 mRNA CTD PMID:31199489 NCBI chr 1:214,434,638...214,439,720
Ensembl chr 1:214,434,626...214,439,720
Ensembl chr 1:214,434,626...214,439,720 		JBrowse link
G Polr1d RNA polymerase I and III subunit D decreases expression ISO Benzalkonium Compounds results in decreased expression of POLR1D mRNA CTD PMID:31199489 NCBI chr12:9,693,828...9,727,416
Ensembl chr12:9,693,779...9,727,489 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases expression ISO Benzalkonium Compounds results in decreased expression of PPARA mRNA CTD PMID:31199489 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752 		JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 increases expression ISO Benzalkonium Compounds results in increased expression of PRKAA2 mRNA CTD PMID:31199489 NCBI chr 5:124,568,845...124,642,569
Ensembl chr 5:124,574,079...124,642,569 		JBrowse link
G Prkag2 protein kinase AMP-activated non-catalytic subunit gamma 2 increases expression ISO Benzalkonium Compounds results in increased expression of PRKAG2 mRNA CTD PMID:31199489 NCBI chr 4:6,559,153...6,799,888
Ensembl chr 4:6,559,545...6,799,632 		JBrowse link
G Prokr2 prokineticin receptor 2 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of PROKR2 mRNA CTD PMID:30171875 NCBI chr 3:125,006,180...125,021,020
Ensembl chr 3:125,009,260...125,017,377 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO Benzalkonium Compounds results in increased expression of PTGS2 mRNA CTD PMID:30806763 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335 		JBrowse link
G Ptx3 pentraxin 3 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of PTX3 mRNA CTD PMID:30171875 NCBI chr 2:158,097,843...158,103,653
Ensembl chr 2:158,097,843...158,103,653 		JBrowse link
G Reg1a regenerating family member 1 alpha multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of REG1 mRNA CTD PMID:30171875 NCBI chr 4:109,497,962...109,500,626
Ensembl chr 4:109,497,962...109,501,082 		JBrowse link
G Reg3g regenerating family member 3 gamma multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of REG3G mRNA CTD PMID:30171875 NCBI chr 4:109,529,679...109,532,234
Ensembl chr 4:109,529,679...109,532,234 		JBrowse link
G Rgl2 ral guanine nucleotide dissociation stimulator-like 2 affects response to substance ISO RGL2 SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr20:5,458,509...5,466,853
Ensembl chr20:5,458,509...5,466,265 		JBrowse link
G Rps18 ribosomal protein S18 affects response to substance ISO RPS18 SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr20:5,441,875...5,445,553
Ensembl chr20:5,441,876...5,445,553 		JBrowse link
G RT1-DOa RT1 class II, locus DOa affects response to substance ISO HLA-DOA SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr20:3,889,106...3,892,360
Ensembl chr20:3,889,370...3,892,449 		JBrowse link
G RT1-DOb RT1 class II, locus DOb affects response to substance ISO HLA-DOB SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr20:4,020,273...4,026,398
Ensembl chr20:4,020,317...4,026,346 		JBrowse link
G RT1-Ha RT1 class II, locus Ha affects response to substance ISO HLA-DPA1 SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr20:3,875,478...3,885,140
Ensembl chr20:3,875,706...3,881,461 		JBrowse link
G Ryr1 ryanodine receptor 1 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of RYR1 mRNA CTD PMID:30171875 NCBI chr 1:87,959,596...88,066,252
Ensembl chr 1:87,959,712...88,066,101 		JBrowse link
G Scd stearoyl-CoA desaturase increases expression
decreases expression		 ISO Benzalkonium Compounds results in increased expression of SCD mRNA
Benzalkonium Compounds results in decreased expression of SCD1 mRNA		 CTD PMID:29155129 PMID:31199489 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729 		JBrowse link
G Serpinb13 serpin family B member 13 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of SERPINB13 mRNA CTD PMID:30171875 NCBI chr13:27,032,048...27,062,620
Ensembl chr13:27,032,048...27,062,620 		JBrowse link
G Serpine1 serpin family E member 1 increases expression ISO Benzalkonium Compounds results in increased expression of SERPINE1 mRNA CTD PMID:30171875 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482 		JBrowse link
G Sesn2 sestrin 2 decreases expression ISO Benzalkonium Compounds results in decreased expression of SESN2 mRNA CTD PMID:31199489 NCBI chr 5:150,684,891...150,703,846
Ensembl chr 5:150,684,133...150,704,117 		JBrowse link
G Sfn stratifin increases expression ISO Benzalkonium Compounds results in increased expression of SFN mRNA CTD PMID:30171875 NCBI chr 5:151,823,422...151,824,937
Ensembl chr 5:151,823,887...151,824,633 		JBrowse link
G Sfrp4 secreted frizzled-related protein 4 decreases expression ISO Benzalkonium Compounds results in decreased expression of SFRP4 mRNA CTD PMID:30171875 NCBI chr17:47,383,983...47,394,065
Ensembl chr17:47,297,489...47,394,328 		JBrowse link
G Siglec8 sialic acid binding Ig-like lectin 8 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of SIGLECE mRNA CTD PMID:30171875 NCBI chr 1:99,576,946...99,587,441
Ensembl chr 1:99,578,372...99,587,205 		JBrowse link
G Slc16a1 solute carrier family 16 member 1 increases expression ISO Benzalkonium Compounds results in increased expression of SLC16A1 mRNA CTD PMID:31199489 NCBI chr 2:207,108,552...207,129,352
Ensembl chr 2:207,108,552...207,128,554 		JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO Benzalkonium Compounds results in increased expression of SLC7A11 mRNA CTD PMID:30806763 NCBI chr 2:139,453,774...139,528,479
Ensembl chr 2:139,453,774...139,528,162 		JBrowse link
G Sox21 SRY-box transcription factor 21 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of SOX21 mRNA CTD PMID:30171875 NCBI chr15:103,438,674...103,441,405
Ensembl chr15:103,440,212...103,441,030 		JBrowse link
G Sprr1a small proline-rich protein 1A increases expression ISO Benzalkonium Compounds results in increased expression of SPRR1A mRNA CTD PMID:30171875 NCBI chr 2:192,669,143...192,671,059
Ensembl chr 2:192,669,143...192,671,059 		JBrowse link
G Sprr1b small proline-rich protein 1B increases expression ISO Benzalkonium Compounds results in increased expression of SPRR1B mRNA CTD PMID:30171875 NCBI chr 2:192,622,972...192,624,848
Ensembl chr 2:192,623,244...192,623,681 		JBrowse link
G Sprr2f small proline rich protein 2F increases expression ISO Benzalkonium Compounds results in increased expression of SPRR2F mRNA CTD PMID:30171875 NCBI chr 2:192,604,978...192,605,208 JBrowse link
G Sqle squalene epoxidase increases expression ISO Benzalkonium Compounds results in increased expression of SQLE mRNA CTD PMID:31199489 NCBI chr 7:99,609,929...99,624,803
Ensembl chr 7:99,609,191...99,624,732 		JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 increases expression ISO Benzalkonium Compounds results in increased expression of SREBF2 mRNA CTD PMID:26919959 NCBI chr 7:123,381,082...123,438,605
Ensembl chr 7:123,381,077...123,438,603 		JBrowse link
G Srms src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of SRMS mRNA CTD PMID:30171875 NCBI chr 3:176,709,742...176,716,146
Ensembl chr 3:176,709,743...176,716,146 		JBrowse link
G St14 ST14 transmembrane serine protease matriptase multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of ST14 mRNA CTD PMID:30171875 NCBI chr 8:32,240,113...32,280,813
Ensembl chr 8:32,240,133...32,280,869 		JBrowse link
G Tapbp TAP binding protein affects response to substance ISO TAPBP SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr20:5,468,056...5,476,007
Ensembl chr20:5,468,078...5,476,193 		JBrowse link
G Tfap2b transcription factor AP-2 beta multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TFAP2B mRNA CTD PMID:30171875 NCBI chr 9:25,410,669...25,440,568
Ensembl chr 9:25,410,669...25,440,411 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression ISO Benzalkonium Compounds results in increased expression of TGFB1 protein CTD PMID:30517752 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199 		JBrowse link
G Tgm3 transglutaminase 3 increases expression ISO Benzalkonium Compounds results in increased expression of TGM3 mRNA CTD PMID:30171875 NCBI chr 3:122,544,783...122,580,836
Ensembl chr 3:122,544,788...122,580,905 		JBrowse link
G Tgm7 transglutaminase 7 decreases expression ISO Benzalkonium Compounds results in decreased expression of TGM7 mRNA CTD PMID:30171875 NCBI chr 3:113,041,577...113,130,128
Ensembl chr 3:113,041,777...113,057,791 		JBrowse link
G Thbs1 thrombospondin 1 increases expression ISO Benzalkonium Compounds results in increased expression of THBS1 mRNA CTD PMID:30171875 NCBI chr 3:109,862,120...109,873,466
Ensembl chr 3:109,862,117...109,873,466 		JBrowse link
G Tlr1 toll-like receptor 1 increases expression ISO Benzalkonium Compounds results in increased expression of TLR1 mRNA CTD PMID:30171875 NCBI chr14:45,062,662...45,065,014
Ensembl chr14:45,062,662...45,081,991 		JBrowse link
G Tlr4 toll-like receptor 4 increases activity ISO Benzalkonium Compounds results in increased activity of TLR4 protein CTD PMID:29514330 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052 		JBrowse link
G Tmprss11b transmembrane serine protease 11B increases expression ISO Benzalkonium Compounds results in increased expression of TMPRSS11B mRNA CTD PMID:30171875 NCBI chr14:24,103,768...24,125,260
Ensembl chr14:24,103,954...24,123,253 		JBrowse link
G Tnf tumor necrosis factor decreases secretion
increases expression		 ISO Benzalkonium Compounds results in decreased secretion of TNF protein
Benzalkonium Compounds results in increased expression of TNF mRNA; Benzalkonium Compounds results in increased expression of TNF protein		 CTD PMID:29953848 PMID:30171875 PMID:30517752 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
G Tnfaip6 TNF alpha induced protein 6 increases expression ISO Benzalkonium Compounds results in increased expression of TNFAIP6 mRNA CTD PMID:30171875 NCBI chr 3:37,545,238...37,564,704
Ensembl chr 3:37,545,238...37,564,699 		JBrowse link
G Tnfrsf13c TNF receptor superfamily member 13C multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TNFRSF13C mRNA CTD PMID:30171875 NCBI chr 7:123,453,799...123,456,289
Ensembl chr 7:123,453,788...123,456,268 		JBrowse link
G Tnfrsf9 TNF receptor superfamily member 9 increases expression ISO Benzalkonium Compounds results in increased expression of TNFRSF9 mRNA CTD PMID:30171875 NCBI chr 5:168,009,245...168,035,813
Ensembl chr 5:168,009,393...168,035,810 		JBrowse link
G Tnfsf8 TNF superfamily member 8 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TNFSF8 mRNA CTD PMID:30171875 NCBI chr 5:79,664,779...79,691,547
Ensembl chr 5:79,664,765...79,691,258 		JBrowse link
G Tp53 tumor protein p53 decreases expression ISO Benzalkonium Compounds results in decreased expression of TP53 mRNA CTD PMID:28236482 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449 		JBrowse link
G Tpi1 triosephosphate isomerase 1 decreases expression ISO Benzalkonium Compounds results in decreased expression of TPI1 mRNA CTD PMID:31199489 NCBI chr 4:157,328,375...157,331,905
Ensembl chr 4:157,328,379...157,331,905
Ensembl chr 9:157,328,379...157,331,905 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 increases expression ISO Benzalkonium Compounds results in increased expression of TREM2 mRNA CTD PMID:30171875 NCBI chr 9:14,611,541...14,618,076
Ensembl chr 9:14,611,561...14,618,013 		JBrowse link
G Tslp thymic stromal lymphopoietin multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TSLP mRNA CTD PMID:30171875 NCBI chr18:25,613,601...25,618,066
Ensembl chr18:25,613,831...25,617,361 		JBrowse link
G Upk3b uroplakin 3B decreases expression ISO Benzalkonium Compounds results in decreased expression of UPK3B mRNA CTD PMID:30171875 NCBI chr12:23,676,169...23,682,395
Ensembl chr12:23,676,152...23,682,381 		JBrowse link
G Uqcrq ubiquinol-cytochrome c reductase, complex III subunit VII decreases expression ISO Benzalkonium Compounds results in decreased expression of UQCRQ mRNA CTD PMID:31199489 NCBI chr10:38,779,132...38,782,489
Ensembl chr10:38,779,132...38,782,419 		JBrowse link
G Vegfd vascular endothelial growth factor D increases expression ISO Benzalkonium Compounds results in increased expression of VEGFD mRNA CTD PMID:20146380 NCBI chr  X:31,816,480...31,852,239
Ensembl chr  X:31,816,436...31,851,715 		JBrowse link
G Vtcn1 V-set domain containing T cell activation inhibitor 1 multiple interactions ISO [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of VTCN1 mRNA CTD PMID:30171875 NCBI chr 2:203,200,435...203,274,264
Ensembl chr 2:203,200,427...203,276,142 		JBrowse link
G Wdr46 WD repeat domain 46 affects response to substance ISO WDR46 SNP affects the susceptibility to Benzalkonium Compounds CTD PMID:27258892 NCBI chr20:5,447,860...5,455,632
Ensembl chr20:5,447,860...5,455,632 		JBrowse link
G Xbp1 X-box binding protein 1 decreases expression ISO Benzalkonium Compounds results in decreased expression of XBP1 mRNA alternative form CTD PMID:28236482 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145 		JBrowse link
G Xcl1 X-C motif chemokine ligand 1 decreases expression ISO Benzalkonium Compounds results in decreased expression of XCL1 mRNA CTD PMID:30171875 NCBI chr13:83,199,402...83,202,845
Ensembl chr13:83,199,264...83,202,864 		JBrowse link
benzethonium chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl2 C-C motif chemokine ligand 2 decreases expression ISO Benzethonium results in decreased expression of CCL2 protein CTD PMID:20116850 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 decreases expression ISO Benzethonium results in decreased expression of CCL3 protein CTD PMID:20116850 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 decreases expression ISO Benzethonium results in decreased expression of CCL4 protein CTD PMID:20116850 NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 decreases expression ISO Benzethonium results in decreased expression of CCL5 protein CTD PMID:20116850 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315 		JBrowse link
G Ifng interferon gamma multiple interactions ISO [Benzethonium co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA CTD PMID:29594315 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419 		JBrowse link
G Il1b interleukin 1 beta decreases expression ISO Benzethonium results in decreased expression of IL1B mRNA CTD PMID:29594315 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726 		JBrowse link
G Il2 interleukin 2 multiple interactions ISO [Benzethonium co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA CTD PMID:29594315 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854 		JBrowse link
G Il6r interleukin 6 receptor decreases expression ISO Benzethonium results in decreased expression of IL6R protein modified form CTD PMID:20116850 NCBI chr 2:189,196,180...189,255,987
Ensembl chr 2:189,205,701...189,254,628 		JBrowse link
G Kcna3 potassium voltage-gated channel subfamily A member 3 decreases activity
multiple interactions		 ISO Benzethonium results in decreased activity of KCNA3 protein
[Benzethonium results in decreased activity of KCNA3 protein] which results in decreased import of Thallium		 CTD PMID:21362439 NCBI chr 2:209,766,767...209,768,344
Ensembl chr 2:209,766,512...209,769,711 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions
decreases activity		 ISO [Benzethonium results in decreased activity of KCNH2 protein] which results in decreased import of Thallium CTD PMID:21362439 PMID:23313619 PMID:24052561 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Benzethonium inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261 		JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression ISO Benzethonium results in decreased expression of VEGFA protein CTD PMID:20116850 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681 		JBrowse link
bretylium tosylate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Bretylium Tosylate inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261 		JBrowse link
butylscopolamine bromide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Butylscopolammonium Bromide inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261 		JBrowse link
chlormequat chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions ISO Chlormequat promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein] CTD PMID:25684042 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464 		JBrowse link
G Bglap bone gamma-carboxyglutamate protein decreases expression EXP Chlormequat results in decreased expression of BGLAP protein CTD PMID:28214531 NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases expression EXP Chlormequat results in decreased expression of CYP11A1 protein CTD PMID:29447956 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 increases expression ISO Chlormequat results in increased expression of CYP7A1 protein CTD PMID:32194361 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431 		JBrowse link
G Gh1 growth hormone 1 increases expression EXP Chlormequat results in increased expression of GH1 protein CTD PMID:31704167 PMID:32622971 NCBI chr10:94,486,204...94,488,181
Ensembl chr10:94,486,205...94,488,180 		JBrowse link
G Ghr growth hormone receptor decreases expression EXP Chlormequat results in decreased expression of GHR mRNA CTD PMID:28214531 NCBI chr 2:53,149,225...53,413,954
Ensembl chr 2:53,150,370...53,413,638 		JBrowse link
G Ghrh growth hormone releasing hormone increases expression EXP Chlormequat results in increased expression of GHRH protein CTD PMID:32622971 NCBI chr 3:153,449,124...153,468,794
Ensembl chr 3:153,449,125...153,468,794 		JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 increases expression EXP Chlormequat results in increased expression of GNRH1 protein CTD PMID:29447956 NCBI chr15:44,441,856...44,446,064
Ensembl chr15:44,442,555...44,442,875
Ensembl chr15:44,442,555...44,442,875 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases expression EXP Chlormequat results in decreased expression of HSD3B1 protein CTD PMID:29447956
G Igf1 insulin-like growth factor 1 affects expression
increases expression		 EXP Chlormequat affects the expression of IGF1 protein
Chlormequat results in increased expression of IGF1 protein		 CTD PMID:28214531 PMID:31704167 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609 		JBrowse link
G Lhb luteinizing hormone subunit beta increases expression EXP Chlormequat results in increased expression of LHB protein CTD PMID:29447956 NCBI chr 1:101,409,992...101,413,725
Ensembl chr 1:101,410,019...101,413,724 		JBrowse link
G Star steroidogenic acute regulatory protein decreases expression EXP Chlormequat results in decreased expression of STAR protein CTD PMID:29447956 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847 		JBrowse link
G Tnfsf11 TNF superfamily member 11 affects expression EXP Chlormequat affects the expression of TNFSF11 mRNA CTD PMID:28214531 NCBI chr15:60,482,527...60,512,704
Ensembl chr15:60,482,527...60,512,704 		JBrowse link
colesevelam hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crp C-reactive protein decreases expression ISO Colesevelam Hydrochloride results in decreased expression of CRP protein CTD PMID:16616026 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions
increases expression		 ISO Colesevelam Hydrochloride promotes the reaction [Simvastatin results in increased expression of HMGCR mRNA]
Colesevelam Hydrochloride results in increased expression of HMGCR mRNA		 CTD PMID:22120639 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654 		JBrowse link
G Ldlr low density lipoprotein receptor increases expression ISO Colesevelam Hydrochloride results in increased expression of LDLR mRNA CTD PMID:22120639 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903 		JBrowse link
ecothiopate iodide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity ISO Echothiophate Iodide results in decreased activity of ACHE protein CTD PMID:16978018 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753 		JBrowse link
G Alb albumin affects binding ISO Echothiophate Iodide binds to ALB protein CTD PMID:15525694 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863 		JBrowse link
G Bche butyrylcholinesterase decreases activity
multiple interactions		 ISO Echothiophate Iodide results in decreased activity of BCHE protein
Echothiophate Iodide inhibits the reaction [BCHE protein results in increased hydrolysis of Butyrylthiocholine]		 CTD PMID:7377577 PMID:16213467 PMID:17698511 PMID:21802514 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395 		JBrowse link
G Nceh1 neutral cholesterol ester hydrolase 1 decreases activity ISO Echothiophate Iodide results in decreased activity of NCEH1 protein CTD PMID:16978018 NCBI chr 2:112,868,834...112,932,622
Ensembl chr 2:112,868,707...112,934,953 		JBrowse link
Hexamethonium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Avp arginine vasopressin multiple interactions EXP Hexamethonium promotes the reaction [Dexamethasone results in increased activity of AVP protein] CTD PMID:3346065 NCBI chr 3:123,117,482...123,119,460
Ensembl chr 3:123,117,492...123,119,460 		JBrowse link
G Bdkrb2 bradykinin receptor B2 affects response to substance ISO BDKRB2 affects the susceptibility to Hexamethonium CTD PMID:10614985 NCBI chr 6:129,399,468...129,429,676
Ensembl chr 6:129,399,468...129,429,676 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions ISO Hexamethonium affects the reaction [Nicotine results in increased expression of BIRC5 protein] CTD PMID:16601104 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 multiple interactions ISO Hexamethonium inhibits the reaction [Nicotine results in decreased expression of CDK4 protein] CTD PMID:15231866 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418 		JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit multiple interactions EXP Hexamethonium results in decreased activity of [CHRNA3 protein binds to CHRNB4 protein] CTD PMID:9687574 NCBI chr 8:59,594,007...59,607,122
Ensembl chr 8:59,592,403...59,607,275 		JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions ISO Hexamethonium inhibits the reaction [epibatidine binds to [CHRNA4 protein binds to CHRNB2 protein]]; Hexamethonium results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein]
Hexamethonium inhibits the reaction [Nicotine results in increased expression of CHRNA4 protein]		 CTD PMID:7756618 PMID:14645658 NCBI chr 3:176,533,182...176,547,965
Ensembl chr 3:176,527,516...176,548,208 		JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions ISO Hexamethonium inhibits the reaction [epibatidine binds to [CHRNA4 protein binds to CHRNB2 protein]]; Hexamethonium results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein]
Hexamethonium inhibits the reaction [Nicotine results in increased expression of CHRNB2 protein]		 CTD PMID:7756618 PMID:14645658 NCBI chr 2:189,088,570...189,096,785
Ensembl chr 2:189,088,570...189,096,785 		JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit multiple interactions EXP Hexamethonium results in decreased activity of [CHRNA3 protein binds to CHRNB4 protein] CTD PMID:9687574 NCBI chr 8:59,610,489...59,629,073
Ensembl chr 8:59,609,693...59,629,133 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP Hexamethonium inhibits the reaction [Hydrochloric Acid results in increased expression of FOS protein] CTD PMID:12588467 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO Hexamethonium inhibits the reaction [Nicotine results in decreased phosphorylation of MAPK1 protein]; Hexamethonium inhibits the reaction [Nicotine results in increased phosphorylation of MAPK1 protein] CTD PMID:18448488 PMID:20106947 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO Hexamethonium inhibits the reaction [Nicotine results in decreased phosphorylation of MAPK3 protein]; Hexamethonium inhibits the reaction [Nicotine results in increased phosphorylation of MAPK3 protein] CTD PMID:18448488 PMID:20106947 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975 		JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions EXP Hexamethonium inhibits the reaction [[Nicotine co-treated with Butylhydroxybutylnitrosamine] results in increased expression of MKI67 protein] CTD PMID:29501575 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454 		JBrowse link
G Npy neuropeptide Y multiple interactions EXP Hexamethonium inhibits the reaction [Nicotine results in increased expression of NPY mRNA] CTD PMID:2233698 NCBI chr 4:79,557,856...79,565,059
Ensembl chr 4:79,557,854...79,565,097
Ensembl chr 4:79,557,854...79,565,097 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO
EXP		 Hexamethonium inhibits the reaction [Nicotine results in increased phosphorylation of STAT3 protein]
Hexamethonium inhibits the reaction [[Nicotine co-treated with Butylhydroxybutylnitrosamine] results in increased expression of STAT3 protein modified form]		 CTD PMID:18448488 PMID:20106947 PMID:29501575 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233 		JBrowse link
G Xiap X-linked inhibitor of apoptosis multiple interactions ISO Hexamethonium affects the reaction [Nicotine results in increased expression of XIAP protein] CTD PMID:16601104 NCBI chr  X:128,409,425...128,455,786
Ensembl chr  X:128,409,472...128,453,000 		JBrowse link
methacholine chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions
increases response to substance		 ISO Cyclosporine inhibits the reaction [[AHR protein results in increased susceptibility to Antigens] which results in increased susceptibility to Methacholine Chloride]
[AHR protein results in increased susceptibility to Antigens] which results in increased susceptibility to Methacholine Chloride; AHR protein results in increased susceptibility to Methacholine Chloride		 CTD PMID:27869817 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 multiple interactions ISO BMPR2 protein affects the susceptibility to [Methacholine Chloride co-treated with Antigens, Dermatophagoides] CTD PMID:22427841 NCBI chr 9:66,568,074...66,683,019
Ensembl chr 9:66,568,074...66,676,494 		JBrowse link
G C3 complement C3 multiple interactions ISO C3 protein affects the susceptibility to [Ozone co-treated with Methacholine Chloride] CTD PMID:14701711 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167 		JBrowse link
G Cacna1e calcium voltage-gated channel subunit alpha1 E multiple interactions EXP 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid affects the reaction [Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]]; 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]]; Atropine inhibits the reaction [Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]]; Calcium inhibits the reaction [Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]]; Heparin affects the reaction [Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]]; Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]; Ro 31-8425 inhibits the reaction [Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]] CTD PMID:12663092 NCBI chr13:71,899,445...72,534,992
Ensembl chr13:71,906,702...72,367,980 		JBrowse link
G Cftr CF transmembrane conductance regulator multiple interactions ISO 3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone inhibits the reaction [Methacholine Chloride promotes the reaction [CFTR protein results in increased export of Chlorides]]; Methacholine Chloride promotes the reaction [CFTR protein results in increased export of Chlorides] CTD PMID:20675434 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676 		JBrowse link
G Cpe carboxypeptidase E increases response to substance ISO CPE gene mutant form results in increased susceptibility to Methacholine Chloride CTD PMID:16002559 NCBI chr16:26,906,716...27,014,811
Ensembl chr16:26,906,716...27,014,813 		JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 multiple interactions ISO Ozone promotes the reaction [CXCR2 protein affects the susceptibility to Methacholine Chloride] CTD PMID:15361358 NCBI chr 9:81,427,275...81,435,065
Ensembl chr 9:81,427,730...81,434,102 		JBrowse link
G Fcer2 Fc fragment of IgE receptor II increases expression ISO Methacholine Chloride results in increased expression of FCER2 protein CTD PMID:15801332 NCBI chr12:2,233,772...2,245,324
Ensembl chr12:2,233,778...2,245,324 		JBrowse link
G Grk3 G protein-coupled receptor kinase 3 affects response to substance ISO GRK3 mutant form affects the susceptibility to Methacholine Chloride CTD PMID:10198406 NCBI chr12:49,626,871...49,750,389
Ensembl chr12:49,626,871...49,746,272 		JBrowse link
G Il1rn interleukin 1 receptor antagonist multiple interactions
increases expression		 ISO IL1RN protein results in decreased susceptibility to [Ozone co-treated with Methacholine Chloride]
Methacholine Chloride results in increased expression of IL1RN protein		 CTD PMID:14754758 PMID:15801332 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614 		JBrowse link
G Lep leptin increases response to substance ISO LEP gene mutant form results in increased susceptibility to Methacholine Chloride CTD PMID:12794034 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO NOS2 protein affects the reaction [2-chloroethyl ethyl sulfide affects the susceptibility to Methacholine Chloride] CTD PMID:22446026 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190 		JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions
decreases response to substance		 ISO N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [NOS3 gene mutant form results in decreased susceptibility to Methacholine Chloride] CTD PMID:22421449 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO NR1I2 protein affects the susceptibility to [5-alpha-Dihydroprogesterone co-treated with Methacholine Chloride] CTD PMID:17159084 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [hydroquinone results in increased expression of TNF protein] which results in increased susceptibility to Methacholine Chloride; Chlorpromazine inhibits the reaction [[hydroquinone results in increased expression of TNF protein] which results in increased susceptibility to Methacholine Chloride]; Cromolyn Sodium inhibits the reaction [[hydroquinone results in increased expression of TNF protein] which results in increased susceptibility to Methacholine Chloride] CTD PMID:22414385 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A increases response to substance ISO TNFRSF1A protein results in increased susceptibility to Methacholine Chloride CTD PMID:21070800 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633 		JBrowse link
G Trpc3 transient receptor potential cation channel, subfamily C, member 3 increases activity ISO Methacholine Chloride results in increased activity of TRPC3 protein CTD PMID:16522635 NCBI chr 2:123,329,954...123,467,574
Ensembl chr 2:123,329,875...123,407,496 		JBrowse link
methyltrioctylammonium chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dio1 iodothyronine deiodinase 1 decreases activity ISO trioctylmethylammonium results in decreased activity of DIO1 protein CTD PMID:30561685 NCBI chr 5:126,894,837...126,911,532
Ensembl chr 5:126,895,286...126,911,520 		JBrowse link
G Dio2 iodothyronine deiodinase 2 decreases activity ISO trioctylmethylammonium results in decreased activity of DIO2 protein CTD PMID:30561685 NCBI chr 6:114,475,156...114,489,443
Ensembl chr 6:114,476,142...114,476,723 		JBrowse link
G Dio3 iodothyronine deiodinase 3 decreases activity ISO trioctylmethylammonium results in decreased activity of DIO3 protein CTD PMID:30561685 NCBI chr 6:134,627,278...134,629,139
Ensembl chr 6:134,627,278...134,629,138 		JBrowse link
tiotropium bromide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrm1 cholinergic receptor, muscarinic 1 affects binding ISO Tiotropium Bromide binds to CHRM1 protein CTD PMID:21870878 NCBI chr 1:224,869,087...224,885,101
Ensembl chr 1:224,882,439...224,884,205 		JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 affects binding ISO Tiotropium Bromide binds to CHRM2 protein CTD PMID:21870878 NCBI chr 4:64,089,028...64,091,090
Ensembl chr 4:64,088,900...64,091,090 		JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 affects binding ISO Tiotropium Bromide binds to CHRM3 protein CTD PMID:21870878 NCBI chr17:63,990,599...64,463,222
Ensembl chr17:63,990,599...63,994,169 		JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 affects binding ISO Tiotropium Bromide binds to CHRM4 protein CTD PMID:21870878 NCBI chr 3:80,833,272...80,841,165
Ensembl chr 3:80,833,272...80,841,006 		JBrowse link
G Chrm5 cholinergic receptor, muscarinic 5 affects binding ISO Tiotropium Bromide binds to CHRM5 protein CTD PMID:21870878 NCBI chr 3:103,966,451...104,018,815
Ensembl chr 3:103,966,451...104,018,861 		JBrowse link
G Edn1 endothelin 1 multiple interactions ISO Tiotropium Bromide inhibits the reaction [Oxotremorine results in increased expression of EDN1 mRNA] CTD PMID:22796455 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324 		JBrowse link
G Pon1 paraoxonase 1 decreases activity ISO Tiotropium Bromide results in decreased activity of PON1 protein CTD PMID:31581362 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372 		JBrowse link
G Tnf tumor necrosis factor decreases secretion ISO Tiotropium Bromide results in decreased secretion of TNF protein CTD PMID:21352583 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
tiquizium bromide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO thiaton results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253 		JBrowse link
G Mpo myeloperoxidase multiple interactions EXP thiaton inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:11855677 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP thiaton inhibits the reaction [Indomethacin results in increased activity of NOS2 protein] CTD PMID:11855677 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190 		JBrowse link
trospium chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
increases transport		 ISO valspodar inhibits the reaction [ABCB1 protein results in increased transport of trospium chloride] CTD PMID:25466967 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515 		JBrowse link
G Slc22a1 solute carrier family 22 member 1 decreases activity
increases metabolic processing		 ISO trospium chloride results in decreased activity of SLC22A1 protein
SLC22A1 protein results in increased metabolism of trospium chloride		 CTD PMID:25466967 NCBI chr 1:48,273,639...48,300,645
Ensembl chr 1:48,273,611...48,300,655 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 decreases activity ISO trospium chloride results in decreased activity of SLC22A2 protein CTD PMID:25466967 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261 		JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 increases metabolic processing
decreases activity		 ISO SLCO1A2 protein results in increased metabolism of trospium chloride
trospium chloride results in decreased activity of SLCO1A2 protein; trospium chloride results in decreased activity of SLCO1A2 protein alternative form		 CTD PMID:25466967 NCBI chr 4:175,969,549...176,026,227
Ensembl chr 4:175,969,549...176,026,163 		JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 decreases activity ISO trospium chloride results in decreased activity of SLCO1B3 protein CTD PMID:25466967 NCBI chr 4:175,814,118...175,881,775
Ensembl chr 4:175,814,118...175,881,768 		JBrowse link
vecuronium bromide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 multiple interactions ISO Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of ABCA1 mRNA]; Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of ABCA1 protein] CTD PMID:30036686 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015 		JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 multiple interactions ISO Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of ABCG1 mRNA]; Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of ABCG1 protein] CTD PMID:30036686 NCBI chr20:9,743,269...9,842,735
Ensembl chr20:9,743,269...9,840,489 		JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 multiple interactions ISO Vecuronium Bromide inhibits the reaction [N-Methylscopolamine binds to CHRM1 protein] CTD PMID:9846649 NCBI chr 1:224,869,087...224,885,101
Ensembl chr 1:224,882,439...224,884,205 		JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 multiple interactions ISO Vecuronium Bromide inhibits the reaction [N-Methylscopolamine binds to CHRM2 protein] CTD PMID:9846649 NCBI chr 4:64,089,028...64,091,090
Ensembl chr 4:64,088,900...64,091,090 		JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 multiple interactions ISO Vecuronium Bromide inhibits the reaction [N-Methylscopolamine binds to CHRM3 protein] CTD PMID:9846649 NCBI chr17:63,990,599...64,463,222
Ensembl chr17:63,990,599...63,994,169 		JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 multiple interactions ISO Vecuronium Bromide inhibits the reaction [N-Methylscopolamine binds to CHRM4 protein] CTD PMID:9846649 NCBI chr 3:80,833,272...80,841,165
Ensembl chr 3:80,833,272...80,841,006 		JBrowse link
G Chrm5 cholinergic receptor, muscarinic 5 multiple interactions ISO Vecuronium Bromide inhibits the reaction [N-Methylscopolamine binds to CHRM5 protein] CTD PMID:9846649 NCBI chr 3:103,966,451...104,018,815
Ensembl chr 3:103,966,451...104,018,861 		JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit multiple interactions ISO Vecuronium Bromide inhibits the reaction [Acetylcholine results in increased activity of [CHRNA3 protein binds to CHRNB2 protein]]; Vecuronium Bromide inhibits the reaction [Acetylcholine results in increased activity of [CHRNA3 protein binds to CHRNB4 protein]] CTD PMID:16931985 NCBI chr 8:59,594,007...59,607,122
Ensembl chr 8:59,592,403...59,607,275 		JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions ISO Vecuronium Bromide inhibits the reaction [Acetylcholine results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]]; Vecuronium Bromide inhibits the reaction [epibatidine binds to [CHRNA4 protein binds to CHRNB2 protein]]; Vecuronium Bromide results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein] CTD PMID:14645658 PMID:16931985 NCBI chr 3:176,533,182...176,547,965
Ensembl chr 3:176,527,516...176,548,208 		JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit multiple interactions ISO Vecuronium Bromide inhibits the reaction [Acetylcholine results in increased activity of CHRNA7 protein] CTD PMID:16931985 NCBI chr 1:123,897,341...124,039,263
Ensembl chr 1:123,899,657...124,039,196 		JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions ISO Vecuronium Bromide inhibits the reaction [Acetylcholine results in increased activity of [CHRNA3 protein binds to CHRNB2 protein]]; Vecuronium Bromide inhibits the reaction [Acetylcholine results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]]; Vecuronium Bromide inhibits the reaction [epibatidine binds to [CHRNA4 protein binds to CHRNB2 protein]]; Vecuronium Bromide results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein] CTD PMID:14645658 PMID:16931985 NCBI chr 2:189,088,570...189,096,785
Ensembl chr 2:189,088,570...189,096,785 		JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit multiple interactions ISO Vecuronium Bromide inhibits the reaction [Acetylcholine results in increased activity of [CHRNA3 protein binds to CHRNB4 protein]] CTD PMID:16931985 NCBI chr 8:59,610,489...59,629,073
Ensembl chr 8:59,609,693...59,629,133 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions ISO Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of CYP11A1 mRNA]; Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of CYP11A1 protein] CTD PMID:31846720 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 multiple interactions ISO Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of CYP19A1 mRNA]; Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of CYP19A1 protein] CTD PMID:30959089 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408 		JBrowse link
G Egr1 early growth response 1 multiple interactions ISO Vecuronium Bromide inhibits the reaction [Nicotine results in increased expression of EGR1 mRNA]; Vecuronium Bromide inhibits the reaction [Nicotine results in increased expression of EGR1 protein] CTD PMID:29486207 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429 		JBrowse link
G Elk1 ETS transcription factor ELK1 multiple interactions ISO Vecuronium Bromide inhibits the reaction [Nicotine results in increased phosphorylation of ELK1 protein] CTD PMID:29486207 NCBI chr  X:1,287,875...1,304,822
Ensembl chr  X:1,297,099...1,304,822 		JBrowse link
G Hdac4 histone deacetylase 4 multiple interactions ISO Vecuronium Bromide inhibits the reaction [Nicotine results in increased expression of HDAC4 mRNA]; Vecuronium Bromide inhibits the reaction [Nicotine results in increased expression of HDAC4 protein] CTD PMID:31846720 NCBI chr 9:99,052,945...99,299,715
Ensembl chr 9:99,057,089...99,299,715 		JBrowse link
G Hexb hexosaminidase subunit beta increases secretion ISO Vecuronium Bromide results in increased secretion of HEXB protein CTD PMID:19758318 NCBI chr 2:27,983,925...28,003,260
Ensembl chr 2:27,984,117...28,003,186 		JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 increases expression
multiple interactions		 ISO Vecuronium Bromide results in increased expression of HSD11B2 mRNA; Vecuronium Bromide results in increased expression of HSD11B2 protein
Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of HSD11B2 mRNA]; Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of HSD11B2 protein]		 CTD PMID:29486207 NCBI chr19:37,476,083...37,481,326
Ensembl chr19:37,476,095...37,481,307 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO Vecuronium Bromide inhibits the reaction [Nicotine results in increased phosphorylation of MAPK1 protein] CTD PMID:29486207 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO Vecuronium Bromide inhibits the reaction [Nicotine results in increased phosphorylation of MAPK3 protein] CTD PMID:29486207 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975 		JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 multiple interactions ISO Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of NR1H2 mRNA]; Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of NR1H2 protein] CTD PMID:30036686 NCBI chr 1:100,554,577...100,559,896
Ensembl chr 1:100,554,544...100,559,942 		JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 multiple interactions ISO Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of NR1H3 mRNA]; Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of NR1H3 protein] CTD PMID:30036686 NCBI chr 3:80,004,130...80,014,197
Ensembl chr 3:80,004,130...80,012,750 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 multiple interactions ISO Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of SCARB1 mRNA]; Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of SCARB1 protein] CTD PMID:30036686 NCBI chr12:36,694,952...36,761,445
Ensembl chr12:36,694,960...36,761,455 		JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions ISO Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of STAR mRNA]; Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of STAR protein] CTD PMID:31846720 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19773
    chemical entity 19773
      molecular entity 19771
        ion 15935
          organic ion 8447
            organic cation 7303
              quaternary ammonium ion 5090
                quaternary ammonium salt 306
                  (11)C-choline chloride 0
                  (1R,2S,1'R,2'S)-doxacurium chloride + 0
                  (1S,2R,1'S,2'R)-doxacurium chloride + 0
                  (R)-oleoylcarnitine hydrochloride 0
                  1,1'-hexadecane-1,16-diylbis(1-methylpyrrolidinium) dibromide 0
                  1,1-dimethyl-4-phenylpiperazinium iodide 7
                  2,4-D choline 0
                  4-DAMP methiodide 0
                  DOSPA trifluoroacetate 0
                  Diponium bromide 0
                  FM 1-43 dye 0
                  FM 4-64 dye 0
                  Hexamethonium 15
                  Polidronium chloride 0
                  Trimethylcetylammonium pentachlorophenate 0
                  Yo-Pro-1 0
                  acetyl-beta-methylthiocholine iodide 0
                  acetylcholine bromide 0
                  acetylcholine chloride 0
                  aclidinium bromide 0
                  ambenonium chloride 1
                  anisotropine methylbromide 0
                  atracurium besylate + 0
                  benzalkonium chloride 233
                  benzethonium chloride 12
                  benzododecinium bromide 0
                  benzododecinium chloride 0
                  bethanechol chloride + 0
                  bretylium tosylate 1
                  butropium bromide 0
                  butylscopolamine bromide 1
                  carpronium chloride 0
                  cetyltrimethylammonium bromide 0
                  cetyltrimethylammonium chloride 0
                  chlormequat chloride 13
                  choline chloride 0
                  cisatracurium besylate 0
                  clidinium bromide 0
                  colesevelam + 3
                  decamethoxine 0
                  decyltrimethylammonium bromide 0
                  demecarium bromide 0
                  dimethylindole red 0
                  diphemanil methylsulfate 0
                  dodecyltrimethylammonium bromide 0
                  doxacurium chloride 0
                  ecothiopate iodide 4
                  edrophonium chloride 0
                  ethyl green 0
                  ethyltrimethylammonium iodide 0
                  fluoromethylcholine (18F) 0
                  glycopyrronium bromide + 0
                  hexafluronium 0
                  iodine green 0
                  ipratropium chloride 0
                  mepiquat chloride 0
                  meso-doxacurium chloride + 0
                  methacholine chloride 17
                  methyl green 0
                  methyltrioctylammonium chloride 3
                  octyltrimethylammonium bromide 0
                  penotonium bromide 0
                  pentamethonium bromide 0
                  poly(2-methacrylolyloxyethyltrimethylammonium chloride) macromolecule + 0
                  poly(diallyldimethylammonium chloride) macromolecule + 0
                  poly[3-(3'-N,N,N-triethylamino-1-propyloxy)-4-methylthiophene-2,5-diyl hydrochloride] macromolecule + 0
                  propyromazine bromide 0
                  quaternium-15 0
                  quaternium-52 0
                  rocuronium bromide 0
                  scopolamine methobromide 0
                  sodium green 0
                  tetrabutylammonium salt + 0
                  tetraethylammonium chloride 0
                  tetramethylammonium bromide 0
                  tetrapropylammonium bromide 0
                  tetrapropylammonium perruthenate 0
                  tiotropium bromide 8
                  tiquizium bromide 3
                  trimethylphenylammonium hydroxide 0
                  trospium chloride 5
                  umeclidinium bromide + 0
                  vecuronium bromide 25
Path 2
Term Annotations click to browse term
  CHEBI ontology 19773
    subatomic particle 19771
      composite particle 19771
        hadron 19771
          baryon 19771
            nucleon 19771
              atomic nucleus 19771
                atom 19771
                  main group element atom 19665
                    main group molecular entity 19665
                      s-block molecular entity 19430
                        hydrogen molecular entity 19424
                          hydrides 18758
                            inorganic hydride 17457
                              pnictogen hydride 17432
                                nitrogen hydride 17277
                                  ammonium 8210
                                    ammonium ion derivative 8206
                                      ammonium compound 5076
                                        organoammonium salt 423
                                          quaternary ammonium salt 306
                                            (11)C-choline chloride 0
                                            (1R,2S,1'R,2'S)-doxacurium chloride + 0
                                            (1S,2R,1'S,2'R)-doxacurium chloride + 0
                                            (R)-oleoylcarnitine hydrochloride 0
                                            1,1'-hexadecane-1,16-diylbis(1-methylpyrrolidinium) dibromide 0
                                            1,1-dimethyl-4-phenylpiperazinium iodide 7
                                            2,4-D choline 0
                                            4-DAMP methiodide 0
                                            DOSPA trifluoroacetate 0
                                            Diponium bromide 0
                                            FM 1-43 dye 0
                                            FM 4-64 dye 0
                                            Hexamethonium 15
                                            Polidronium chloride 0
                                            Trimethylcetylammonium pentachlorophenate 0
                                            Yo-Pro-1 0
                                            acetyl-beta-methylthiocholine iodide 0
                                            acetylcholine bromide 0
                                            acetylcholine chloride 0
                                            aclidinium bromide 0
                                            ambenonium chloride 1
                                            anisotropine methylbromide 0
                                            atracurium besylate + 0
                                            benzalkonium chloride 233
                                            benzethonium chloride 12
                                            benzododecinium bromide 0
                                            benzododecinium chloride 0
                                            bethanechol chloride + 0
                                            bretylium tosylate 1
                                            butropium bromide 0
                                            butylscopolamine bromide 1
                                            carpronium chloride 0
                                            cetyltrimethylammonium bromide 0
                                            cetyltrimethylammonium chloride 0
                                            chlormequat chloride 13
                                            choline chloride 0
                                            cisatracurium besylate 0
                                            clidinium bromide 0
                                            colesevelam + 3
                                            decamethoxine 0
                                            decyltrimethylammonium bromide 0
                                            demecarium bromide 0
                                            dimethylindole red 0
                                            diphemanil methylsulfate 0
                                            dodecyltrimethylammonium bromide 0
                                            doxacurium chloride 0
                                            ecothiopate iodide 4
                                            edrophonium chloride 0
                                            ethyl green 0
                                            ethyltrimethylammonium iodide 0
                                            fluoromethylcholine (18F) 0
                                            glycopyrronium bromide + 0
                                            hexafluronium 0
                                            iodine green 0
                                            ipratropium chloride 0
                                            mepiquat chloride 0
                                            meso-doxacurium chloride + 0
                                            methacholine chloride 17
                                            methyl green 0
                                            methyltrioctylammonium chloride 3
                                            octyltrimethylammonium bromide 0
                                            penotonium bromide 0
                                            pentamethonium bromide 0
                                            poly(2-methacrylolyloxyethyltrimethylammonium chloride) macromolecule + 0
                                            poly(diallyldimethylammonium chloride) macromolecule + 0
                                            poly[3-(3'-N,N,N-triethylamino-1-propyloxy)-4-methylthiophene-2,5-diyl hydrochloride] macromolecule + 0
                                            propyromazine bromide 0
                                            quaternium-15 0
                                            quaternium-52 0
                                            rocuronium bromide 0
                                            scopolamine methobromide 0
                                            sodium green 0
                                            tetrabutylammonium salt + 0
                                            tetraethylammonium chloride 0
                                            tetramethylammonium bromide 0
                                            tetrapropylammonium bromide 0
                                            tetrapropylammonium perruthenate 0
                                            tiotropium bromide 8
                                            tiquizium bromide 3
                                            trimethylphenylammonium hydroxide 0
                                            trospium chloride 5
                                            umeclidinium bromide + 0
                                            vecuronium bromide 25
paths to the root