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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2-ylidene)acetamide
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Accession:CHEBI:94513 term browser browse the term
Definition:A thiadiazole that has formula C5H8N4O3S2.
Synonyms:related_synonym: Formula=C5H8N4O3S2;   InChI=1S/C5H8N4O3S2/c1-3(10)7-4-9(2)8-5(13-4)14(6,11)12/h1-2H3,(H2,6,11,12);   InChIKey=FLOSMHQXBMRNHR-UHFFFAOYSA-N;   N-Methylacetazolamide;   SMILES=CC(=O)N=C1N(N=C(S1)S(=O)(=O)N)C;   metazolamide;   methenamide;   neptazane;   neptazaneat
 xref: CAS:554-57-4;   Drug_Central:1741;   LINCS:LSM-5311
 xref_mesh: MESH:D008704


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N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2-ylidene)acetamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Car1 carbonic anhydrase 1 multiple interactions ISO Methazolamide binds to and results in decreased activity of CA1 protein CTD PMID:17826101 NCBI chr 3:14,831,274...14,873,425
Ensembl chr 3:14,831,276...14,873,428 		JBrowse link
G Car2 carbonic anhydrase 2 multiple interactions
decreases activity		 ISO Methazolamide binds to and results in decreased activity of CA2 protein
Methazolamide results in decreased activity of CA2 protein		 CTD PMID:16858005 PMID:17826101 NCBI chr 3:14,951,329...14,965,830
Ensembl chr 3:14,951,333...14,965,830 		JBrowse link
G Car3 carbonic anhydrase 3 multiple interactions ISO Methazolamide binds to and results in decreased activity of CA3 protein CTD PMID:17826101 NCBI chr 3:14,928,598...14,937,441
Ensembl chr 3:14,928,572...14,937,583 		JBrowse link
G Clu clusterin affects expression ISO Methazolamide affects the expression of CLU protein CTD PMID:12388792 NCBI chr14:66,206,093...66,218,992
Ensembl chr14:66,205,932...66,218,996 		JBrowse link
G Gal galanin and GMAP prepropeptide affects expression ISO Methazolamide affects the expression of GAL protein CTD PMID:12388792 NCBI chr19:3,459,915...3,464,544
Ensembl chr19:3,459,915...3,464,544 		JBrowse link
G Gap43 growth associated protein 43 affects expression ISO Methazolamide affects the expression of GAP43 protein CTD PMID:12388792 NCBI chr16:42,068,915...42,161,014
Ensembl chr16:42,068,805...42,161,014 		JBrowse link
G Ret ret proto-oncogene affects expression ISO Methazolamide affects the expression of RET protein CTD PMID:12388792 NCBI chr 6:118,128,709...118,174,705
Ensembl chr 6:118,128,706...118,174,679 		JBrowse link
G Timp1 tissue inhibitor of metalloproteinase 1 affects expression ISO Methazolamide affects the expression of TIMP1 protein CTD PMID:12388792 NCBI chr  X:20,736,524...20,740,972
Ensembl chr  X:20,736,405...20,740,974 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22298
    chemical entity 22279
      atom 22292
        nonmetal atom 22103
          sulfur atom 18740
            sulfur molecular entity 18727
              organosulfur compound 18196
                sulfonamide 5325
                  N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2-ylidene)acetamide 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 22298
    subatomic particle 22274
      composite particle 22292
        hadron 22292
          baryon 22292
            nucleon 22274
              atomic nucleus 22292
                atom 22292
                  main group element atom 22153
                    p-block element atom 22153
                      chalcogen 21511
                        oxygen atom 21489
                          oxygen molecular entity 21473
                            hydroxides 20843
                              oxoacid 20141
                                chalcogen oxoacid 14406
                                  sulfur oxoacid 14192
                                    sulfonic acid 12027
                                      sulfonic acid derivative 12050
                                        sulfonamide 5325
                                          N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2-ylidene)acetamide 8
paths to the root