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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:glycyrol
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Accession:CHEBI:80832 term browser browse the term
Definition:A member of the class of coumestans that is coumestan substituted by hydroxy groups at positions 1 and 9, a methoxy group at position 3 and a prenyl group at position 2 respectively.
Synonyms:exact_synonym: 3,9-dihydroxy-1-methoxy-2-(3-methylbut-2-en-1-yl)-6H-[1]benzofuro[3,2-c][1]benzopyran-6-one
 related_synonym: 1,9-Dihydroxy-3-methoxy-2-prenylcoumestan;   Formula=C21H18O6;   InChI=1S/C21H18O6/c1-10(2)4-6-12-14(23)9-16-18(19(12)25-3)20-17(21(24)27-16)13-7-5-11(22)8-15(13)26-20/h4-5,7-9,22-23H,6H2,1-3H3;   InChIKey=LWESBHWAOZORCQ-UHFFFAOYSA-N;   Neoglycyrol;   SMILES=COc1c(CC=C(C)C)c(O)cc2oc(=O)c3c4ccc(O)cc4oc3c12
 xref: CAS:23013-84-5;   HMDB:HMDB0033882;   KEGG:C16968;   KNApSAcK:C00009777;   LIPID_MAPS_instance:LMPK12090044
 xref_mesh: MESH:C531349
 xref: PMID:25445757;   PMID:25614969


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glycyrol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1b interleukin 1 beta multiple interactions ISO glycyrol inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA] CTD PMID:18666753 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO glycyrol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA] CTD PMID:18666753 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
increases expression		 ISO glycyrol inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased degradation of NFKBIA protein]
glycyrol results in increased expression of NFKBIA protein		 CTD PMID:18666753 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO glycyrol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA] CTD PMID:18666753 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO glycyrol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] CTD PMID:18666753 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    role 19784
      application 19627
        pharmaceutical 19468
          drug 19468
            antineoplastic agent 17749
              glycyrol 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    p-block element atom 19756
                      carbon group element atom 19705
                        carbon atom 19702
                          organic molecular entity 19702
                            heteroorganic entity 19460
                              organochalcogen compound 19224
                                organooxygen compound 19141
                                  ester 17332
                                    carboxylic ester 16714
                                      lactone 13224
                                        delta-lactone 3942
                                          coumestan 1782
                                            glycyrol 5
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