CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: diaminopyridine
Accession: CHEBI:51598
browse the term
Definition: Compounds containing a pyridine skeleton substituted by two amino groups.
Synonyms: related_synonym: diaminopyridines
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Alk
ALK receptor tyrosine kinase
multiple interactions
ISO
2,4-diaminopyridine analog binds to and results in decreased activity of ALK protein
CTD
PMID:22564207
NCBI chr 6:22,879,653...23,599,636
Ensembl chr 6:22,880,625...23,598,034
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Nanog
Nanog homeobox
decreases expression
ISO
Chir 98014 results in decreased expression of NANOG mRNA
CTD
PMID:22723015
NCBI chr 4:155,943,737...155,951,116
Ensembl chr 4:155,943,737...155,951,116
G
Otx2
orthodenticle homeobox 2
decreases expression
ISO
Chir 98014 results in decreased expression of OTX2 mRNA
CTD
PMID:22723015
NCBI chr15:21,942,233...21,953,034
Ensembl chr15:21,943,191...21,953,416
G
Pax6
paired box 6
decreases expression
ISO
Chir 98014 results in decreased expression of PAX6 mRNA
CTD
PMID:22723015
NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Abcb4
ATP binding cassette subfamily B member 4
decreases activity
ISO
Phenazopyridine results in decreased activity of ABCB4 protein
CTD
PMID:28437613
NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
G
Utrn
utrophin
increases expression
ISO
Phenazopyridine results in increased expression of UTRN mRNA
CTD
PMID:22028826
NCBI chr 1:6,720,854...7,224,313
Ensembl chr 1:6,722,594...7,224,313
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