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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:phenazopyridine
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Accession:CHEBI:71416 term browser browse the term
Definition:A diaminopyridine that is 2,6-diaminopyridine substituted at position 3 by a phenylazo group. A local anesthetic that has topical analgesic effect on mucosa lining of the urinary tract. Its use is limited by problems with toxicity (primarily blood disorders) and potential carcinogenicity.
Synonyms:exact_synonym: 3-(phenyldiazenyl)pyridine-2,6-diamine
 related_synonym: 2,6-Diamino-3-(phenylazo)pyridine;   2,6-Diamino-3-phenylazopyridine;   3-(Phenylazo)-2,6-pyridinediamine;   Formula=C11H11N5;   InChI=1S/C11H11N5/c12-10-7-6-9(11(13)14-10)16-15-8-4-2-1-3-5-8/h1-7H,(H4,12,13,14);   InChIKey=QPFYXYFORQJZEC-UHFFFAOYSA-N;   SMILES=Nc1ccc(N=Nc2ccccc2)c(N)n1;   fenazopiridina;   phenazopyridinum
 alt_id: CHEBI:8057
 xref: Beilstein:184497;   CAS:94-78-0;   DrugBank:DB01438;   HMDB:HMDB0015506;   KEGG:C07429;   KEGG:D08346;   LINCS:LSM-3705
 xref_mesh: MESH:D010621
 xref: PMID:19300288;   PMID:19744778;   PMID:20196783;   PMID:20467292;   PMID:20636989;   PMID:20976818;   PMID:21147318;   PMID:21376167;   PMID:21681956;   PMID:21789523;   PMID:21856805;   PMID:22110938;   PMID:22987905;   PMID:23030327;   PMID:28166217;   Patent:US2009247628;   Patent:WO2008033466;   Patent:WO2010071878;   Reaxys:184497;   Wikipedia:Phenazopyridine
 cyclic_relationship: is_conjugate_base_of CHEBI:71420


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phenazopyridine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb4 ATP binding cassette subfamily B member 4 decreases activity ISO Phenazopyridine results in decreased activity of ABCB4 protein CTD PMID:28437613 NCBI chr 4:22,133,984...22,192,687
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Utrn utrophin increases expression ISO Phenazopyridine results in increased expression of UTRN mRNA CTD PMID:22028826 NCBI chr 1:6,451,809...6,970,040
Ensembl chr 1:6,451,810...6,970,040
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19781
    role 19726
      biological role 19726
        aetiopathogenetic role 18980
          carcinogenic agent 18364
            phenazopyridine 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19781
    subatomic particle 19779
      composite particle 19779
        hadron 19779
          baryon 19779
            nucleon 19779
              atomic nucleus 19779
                atom 19779
                  main group element atom 19669
                    main group molecular entity 19669
                      s-block molecular entity 19434
                        hydrogen molecular entity 19429
                          hydrides 18757
                            inorganic hydride 17455
                              pnictogen hydride 17431
                                nitrogen hydride 17278
                                  azane 17010
                                    ammonia 17009
                                      organic amino compound 17008
                                        aromatic amine 13681
                                          aminopyridine 365
                                            diaminopyridine 6
                                              phenazopyridine 2
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