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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:TRAM-34
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Accession:CHEBI:34990 term browser browse the term
Definition:An organochlorine compound that has formula C22H17ClN2.
Synonyms:related_synonym: 1-[(2-Chlorophenyl)diphenylmethyl]-1H-pyrazole;   Formula=C22H17ClN2;   InChI=1S/C22H17ClN2/c23-21-15-8-7-14-20(21)22(25-17-9-16-24-25,18-10-3-1-4-11-18)19-12-5-2-6-13-19/h1-17H;   InChIKey=KBFUQFVFYYBHBT-UHFFFAOYSA-N;   SMILES=Clc1ccccc1C(c1ccccc1)(c1ccccc1)n1cccn1
 xref: KEGG:C13784
 xref_mesh: MESH:C411671



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TRAM-34 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle multiple interactions EXP TRAM 34 inhibits the reaction [Paraquat results in increased expression of ACTA2 protein] CTD PMID:30036685 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Esr1 estrogen receptor 1 decreases expression ISO TRAM 34 results in decreased expression of ESR1 mRNA CTD PMID:20050851 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 decreases activity ISO TRAM 34 results in decreased activity of KCNN4 protein CTD PMID:20050851 NCBI chr 1:79,956,380...79,974,354
Ensembl chr 1:79,959,322...79,974,340
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO TRAM 34 binds to and results in increased activity of NR1I2 protein CTD PMID:20869355 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO TRAM 34 binds to and results in increased activity of NR1I3 protein alternative form CTD PMID:20869355 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link
G Pgr progesterone receptor increases expression ISO TRAM 34 results in increased expression of PGR mRNA CTD PMID:20050851 NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19890
    chemical entity 19867
      molecular entity 19867
        main group molecular entity 19806
          p-block molecular entity 19806
            halogen molecular entity 18683
              chlorine molecular entity 18480
                organochlorine compound 18321
                  TRAM-34 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19890
    subatomic particle 19867
      composite particle 19888
        hadron 19888
          baryon 19888
            nucleon 19867
              atomic nucleus 19888
                atom 19888
                  main group element atom 19806
                    p-block element atom 19806
                      p-block molecular entity 19806
                        carbon group molecular entity 19766
                          organic molecular entity 19743
                            heteroorganic entity 19502
                              organohalogen compound 18520
                                organochlorine compound 18321
                                  TRAM-34 6
paths to the root