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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:19-Nor-17alpha-pregn-5(10)-en-20-yne-3alpha,17beta-diol
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Accession:CHEBI:34186 term browser browse the term
Definition:A 17-hydroxy steroid that has formula C20H28O2.
Synonyms:related_synonym: 17alpha-Ethynylestr-5(10)-ene-3alpha,17beta-diol;   Formula=C20H28O2;   InChI=1S/C20H28O2/c1-3-20(22)11-9-18-17-6-4-13-12-14(21)5-7-15(13)16(17)8-10-19(18,20)2/h1,14,16-18,21-22H,4-12H2,2H3/t14-,16-,17-,18+,19+,20+/m1/s1;   InChIKey=XSQAQKNJHGGMRV-KXMHTTHWSA-N;   SMILES=C[C@]12CC[C@H]3[C@@H](CCC4=C3CC[C@@H](O)C4)[C@@H]1CC[C@@]2(O)C#C
 xref: CAS:21466-08-0;   KEGG:C14652
 xref_mesh: MESH:C002029


show annotations for term's descendants           Sort by:
19-Nor-17alpha-pregn-5(10)-en-20-yne-3alpha,17beta-diol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCNA2 cyclin A2 decreases expression ISO 17alpha-ethynylestr-5(10)-ene-3alpha,17beta-diol results in decreased expression of CCNA2 protein CTD PMID:16019103 NCBI chr 4:121,816,444...121,823,883
Ensembl chr 4:121,816,444...121,823,883 		JBrowse link
G CCNE1 cyclin E1 decreases expression ISO 17alpha-ethynylestr-5(10)-ene-3alpha,17beta-diol results in decreased expression of CCNE1 protein CTD PMID:16019103 NCBI chr19:29,811,991...29,824,312
Ensembl chr19:29,811,991...29,824,312 		JBrowse link
G CDK2 cyclin dependent kinase 2 multiple interactions ISO 17alpha-ethynylestr-5(10)-ene-3alpha,17beta-diol results in decreased expression of and results in decreased activity of CDK2 protein CTD PMID:16019103 NCBI chr12:55,966,830...55,972,789
Ensembl chr12:55,966,781...55,972,789 		JBrowse link
G CDK4 cyclin dependent kinase 4 decreases expression ISO 17alpha-ethynylestr-5(10)-ene-3alpha,17beta-diol results in decreased expression of CDK4 protein CTD PMID:16019103 NCBI chr12:57,747,727...57,752,310
Ensembl chr12:57,747,727...57,756,013 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A increases expression ISO 17alpha-ethynylestr-5(10)-ene-3alpha,17beta-diol results in increased expression of CDKN1A protein CTD PMID:16019103 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337 		JBrowse link
G TP53 tumor protein p53 increases expression ISO 17alpha-ethynylestr-5(10)-ene-3alpha,17beta-diol results in increased expression of TP53 protein CTD PMID:16019103 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26040
    chemical entity 26019
      molecular entity 25997
        polyatomic entity 25882
          heteroatomic molecular entity 25533
            hydroxides 24053
              organic hydroxy compound 22062
                hydroxy steroid 15536
                  17-hydroxy steroid 15138
                    19-Nor-17alpha-pregn-5(10)-en-20-yne-3alpha,17beta-diol 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 26040
    subatomic particle 26015
      composite particle 26015
        hadron 26015
          baryon 26015
            nucleon 26015
              atomic nucleus 26015
                atom 26015
                  main group element atom 25840
                    p-block element atom 25840
                      carbon group element atom 25437
                        carbon atom 25395
                          organic molecular entity 25395
                            organic molecule 25223
                              organic cyclic compound 24277
                                organic polycyclic compound 18790
                                  steroid 15858
                                    hydroxy steroid 15536
                                      17-hydroxy steroid 15138
                                        19-Nor-17alpha-pregn-5(10)-en-20-yne-3alpha,17beta-diol 6
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