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->8)-alpha-Neu5Ac-(2->3)-[beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)]-beta-D-Gal-(1->4)-yl group - Ontology Report - Rat Genome Database

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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:->8)-alpha-Neu5Ac-(2->3)-[beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)]-beta-D-Gal-(1->4)-yl group
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Accession:CHEBI:142514 term browser browse the term
Definition:An organic group forming part of, and a proposed epitope within, ganglioside GM1. The ->8) linkage to Neu5Ac may represent an additional alpha2->8-linked sialic acid residue, while the -(1->4)-yl may represent -(1->4)-glucosyl.
Synonyms:exact_synonym: ->8)-5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranonosyl-(2->3)-[beta-D-galactopyranosyl-(1->3)-2-acetamido-2-deoxy-beta-D-galactopyranosyl-(1->4)]-beta-D-galactopyranosyl-(1->4)-glycosyl
 related_synonym: ->8)-5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulosyl-(2->3)-[beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosyl-(1->4)]-beta-D-galactosyl-(1->4)-yl;   Formula=C31H50N2O22;   Galbeta1-3GalNAcbeta1-4(R'-NeuAcalpha2-3)Galbeta1-4-R\";   R'-alpha-Neu5Ac-(2->3)-[beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)]-beta-D-Gal-(1->4)-R\";   SMILES=*[C@H]1[C@@H]([C@H]([C@H]([C@H](O1)CO)O[C@H]2[C@@H]([C@H]([C@H]([C@H](O2)CO)O)O[C@H]3[C@@H]([C@H]([C@H]([C@H](O3)CO)O)O)O)NC(C)=O)O[C@@]4(C[C@@H]([C@H]([C@](O4)([H])[C@H](O)[C@@H](CO)*)NC(C)=O)O)C(=O)O)O
 xref: PMID:7691279

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ganglioside GM1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD14 CD14 molecule multiple interactions ISO CD14 protein affects the reaction [G(M1) Ganglioside results in increased secretion of Nitric Oxide] CTD PMID:16651628 NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A increases expression ISO G(M1) Ganglioside results in increased expression of CDKN1A protein CTD PMID:15654767 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,397 		JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B decreases expression ISO G(M1) Ganglioside results in decreased expression of CDKN1B protein CTD PMID:15654767 NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,685,498...12,722,369 		JBrowse link
G NPC1 NPC intracellular cholesterol transporter 1 affects localization ISO NPC1 affects the localization of G(M1) Ganglioside CTD PMID:12183525 NCBI chr18:23,506,184...23,586,506
Ensembl chr18:23,506,184...23,586,506 		JBrowse link
G NTRK1 neurotrophic receptor tyrosine kinase 1 multiple interactions ISO G(M1) Ganglioside inhibits the reaction [Methylmercury Compounds results in decreased phosphorylation of NTRK1 protein]; G(M1) Ganglioside inhibits the reaction [staurosporine aglycone results in decreased phosphorylation of NTRK1 protein] CTD PMID:25545984 NCBI chr 1:156,815,750...156,881,850
Ensembl chr 1:156,815,636...156,881,850 		JBrowse link
G PLD1 phospholipase D1 multiple interactions ISO PLD1 protein affects the reaction [dinitrophenyl-bovine serum albumin affects the localization of G(M1) Ganglioside] CTD PMID:19794068 NCBI chr 3:171,600,404...171,810,483
Ensembl chr 3:171,600,404...171,810,950 		JBrowse link
G PLD2 phospholipase D2 multiple interactions ISO PLD2 protein affects the reaction [dinitrophenyl-bovine serum albumin affects the localization of G(M1) Ganglioside] CTD PMID:19794068 NCBI chr17:4,807,152...4,823,430
Ensembl chr17:4,807,152...4,823,434 		JBrowse link
G SLC18A2 solute carrier family 18 member A2 increases expression ISO G(M1) Ganglioside results in increased expression of SLC18A2 mRNA CTD PMID:14552908 NCBI chr10:117,241,114...117,279,430
Ensembl chr10:117,241,093...117,279,430 		JBrowse link
G SLC6A3 solute carrier family 6 member 3 increases expression ISO G(M1) Ganglioside results in increased expression of SLC6A3 mRNA CTD PMID:14552908 NCBI chr 5:1,392,794...1,445,440
Ensembl chr 5:1,392,794...1,445,440 		JBrowse link
G TH tyrosine hydroxylase increases activity ISO G(M1) Ganglioside results in increased activity of TH protein CTD PMID:14552908 NCBI chr11:2,163,929...2,171,815
Ensembl chr11:2,163,929...2,171,815 		JBrowse link
G TLR4 toll like receptor 4 decreases expression ISO G(M1) Ganglioside results in decreased expression of TLR4 protein CTD PMID:16651628 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26827
    chemical entity 26807
      group 26676
        organic group 23959
          ->8)-alpha-Neu5Ac-(2->3)-[beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)]-beta-D-Gal-(1->4)-yl group 11
            ganglioside GM1 + 11
Path 2
Term Annotations click to browse term
  CHEBI ontology 26827
    subatomic particle 26803
      composite particle 26803
        hadron 26803
          baryon 26803
            nucleon 26803
              atomic nucleus 26803
                atom 26803
                  group 26676
                    organic group 23959
                      ->8)-alpha-Neu5Ac-(2->3)-[beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)]-beta-D-Gal-(1->4)-yl group 11
                        ganglioside GM1 + 11
paths to the root