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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Xylometazoline
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Accession:CHEBI:10082 term browser browse the term
Definition:An alkylbenzene that has formula C16H24N2.
Synonyms:related_synonym: Formula=C16H24N2;   InChI=1S/C16H24N2/c1-11-8-13(16(3,4)5)9-12(2)14(11)10-15-17-6-7-18-15/h8-9H,6-7,10H2,1-5H3,(H,17,18);   InChIKey=HUCJFAOMUPXHDK-UHFFFAOYSA-N;   SMILES=Cc1cc(cc(C)c1CC1=NCCN1)C(C)(C)C;   otrivine;   rhinoxilin;   xylometazoline HCl;   xylometazoline hydrochloride
 xref: CAS:526-36-3;   Drug_Central:3658;   HMDB:HMDB0015640;   KEGG:C07913;   KEGG:D08684;   LINCS:LSM-5262
 xref_mesh: MESH:C009695


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Xylometazoline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra1a adrenoceptor alpha 1A affects binding
multiple interactions		 ISO xylometazoline binds to ADRA1A protein
xylometazoline inhibits the reaction [ADRA1A protein binds to Prazosin]		 CTD PMID:20030735 NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500 		JBrowse link
G Adra1b adrenoceptor alpha 1B affects binding
multiple interactions		 ISO xylometazoline binds to ADRA1B protein
xylometazoline inhibits the reaction [ADRA1B protein binds to Prazosin]		 CTD PMID:20030735 NCBI chr10:28,255,025...28,373,418
Ensembl chr10:28,255,025...28,312,919 		JBrowse link
G Adra1d adrenoceptor alpha 1D affects binding
multiple interactions		 ISO xylometazoline binds to ADRA1D protein
xylometazoline inhibits the reaction [ADRA1D protein binds to Prazosin]		 CTD PMID:20030735 NCBI chr 3:118,793,356...118,809,354
Ensembl chr 3:118,793,346...118,809,354 		JBrowse link
G Adra2a adrenoceptor alpha 2A affects binding
multiple interactions		 ISO xylometazoline binds to ADRA2A protein
xylometazoline inhibits the reaction [ADRA2A protein binds to 2-methoxyidazoxan]		 CTD PMID:20030735 NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365 		JBrowse link
G Adra2b adrenoceptor alpha 2B multiple interactions ISO [xylometazoline binds to and results in increased activity of ADRA2B protein] which results in increased abundance of Calcium; xylometazoline binds to and results in increased activity of ADRA2B protein; xylometazoline inhibits the reaction [ADRA2B protein binds to 2-methoxyidazoxan] CTD PMID:20030735 NCBI chr 3:114,585,174...114,589,220
Ensembl chr 3:114,585,169...114,589,355 		JBrowse link
G Adra2c adrenoceptor alpha 2C affects binding
multiple interactions		 ISO xylometazoline binds to ADRA2C protein
xylometazoline inhibits the reaction [ADRA2C protein binds to 2-methoxyidazoxan]		 CTD PMID:20030735 NCBI chr14:75,470,884...75,472,846
Ensembl chr14:75,471,143...75,472,846 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO xylometazoline inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19848
    role 19824
      chemical role 19460
        environmental contaminant 18857
          benzene 5798
            alkylbenzene 3515
              Xylometazoline 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 19848
    subatomic particle 19846
      composite particle 19846
        hadron 19846
          baryon 19846
            nucleon 19846
              atomic nucleus 19846
                atom 19846
                  main group element atom 19796
                    main group molecular entity 19796
                      s-block molecular entity 19629
                        hydrogen molecular entity 19616
                          hydrides 19122
                            organic hydride 18693
                              organic fundamental parent 18693
                                hydrocarbon 18438
                                  cyclic hydrocarbon 17231
                                    monocyclic hydrocarbon 6146
                                      annulene 5798
                                        aromatic annulene 5798
                                          benzene 5798
                                            alkylbenzene 3515
                                              Xylometazoline 7
paths to the root