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ONTOLOGY REPORT - ANNOTATIONS

Term:androgen receptor signaling pathway
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Accession:GO:0030521 term browser browse the term
Definition:A nuclear receptor-mediated signaling pathway initiated by an androgen binding to an intracellular receptor of the nuclear receptor protein family, and ending with regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: androgen receptor signalling pathway;   nuclear-receptor-mediated androgen receptor signaling pathway


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androgen receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Andpro androgen regulated protein IMP RGD PMID:8262963 RGD:1566559 NCBI chr 3:136,718,601...136,725,131
Ensembl chr 3:136,718,602...136,724,966 		JBrowse link
G Ar androgen receptor NOT|involved_in
acts_upstream_of_or_within		 IMP
ISO
IEA		 (PMID:19244107)
(PMID:10428808), (PMID:12799378), (PMID:17277772), (PMID:19886863), (PMID:20048160)
(PMID:15199138), (PMID:15660130)
(PMID:18761815)
GO_REF:0000107		 RGD
Ensembl		 PMID:10428808 PMID:12799378 PMID:15199138 PMID:15660130 PMID:17277772 More... GO_REF:0000107, RGD:1298681 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Cst11 cystatin 11 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 3:136,211,414...136,214,138
Ensembl chr 3:136,211,414...136,214,138 		JBrowse link
G Daxx death-domain associated protein involved_in ISO
IEA		 (PMID:15572661)
GO_REF:0000107		 RGD
Ensembl		 PMID:15572661 GO_REF:0000107 NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843 		JBrowse link
G Ddx17 DEAD-box helicase 17 involved_in ISO (PMID:24275493) RGD PMID:24275493 NCBI chr 7:111,091,127...111,109,353
Ensembl chr 7:111,089,445...111,109,193 		JBrowse link
G Ddx5 DEAD-box helicase 5 involved_in ISO (PMID:24275493) RGD PMID:24275493 NCBI chr10:91,723,508...91,732,210
Ensembl chr10:91,723,508...91,732,283 		JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 acts_upstream_of_or_within ISO MGI:3573790 (PMID:15660130) RGD PMID:15660130 NCBI chr 5:55,842,414...55,853,326
Ensembl chr 5:55,842,426...55,853,967 		JBrowse link
G Esr2 estrogen receptor 2 acts_upstream_of ISO MGI:2152217 (PMID:12370428) RGD PMID:12370428 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Fkbp4 FKBP prolyl isomerase 4 acts_upstream_of_or_within ISO MGI:3690438 (PMID:17142810) RGD PMID:17142810 NCBI chr 4:161,703,379...161,711,833
Ensembl chr 4:161,703,379...161,711,833 		JBrowse link
G Igf1 insulin-like growth factor 1 acts_upstream_of ISO MGI:2152423 (PMID:18827067) RGD PMID:18827067 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Kdm3a lysine demethylase 3A involved_in ISO
IEA		 (PMID:16603237)
GO_REF:0000107		 RGD
Ensembl		 PMID:16603237 GO_REF:0000107 NCBI chr 4:103,630,907...103,675,073
Ensembl chr 4:103,630,908...103,675,073 		JBrowse link
G Kdm4c lysine demethylase 4C involved_in ISO (PMID:17277772) RGD PMID:17277772 NCBI chr 5:88,100,710...88,306,821
Ensembl chr 5:88,100,733...88,306,818 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 involved_in ISO
IEA		 (PMID:22031296)
GO_REF:0000107		 RGD
Ensembl		 PMID:22031296 GO_REF:0000107 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Nkx3-1 NK3 homeobox 1 involved_in ISO (PMID:19886863) RGD PMID:19886863 NCBI chr15:44,473,851...44,476,443
Ensembl chr15:44,473,851...44,476,441 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISS
ISO		 GO_REF:0000024
(PMID:17510388)		 ParkinsonsUK-UCL
RGD		 PMID:17510388 GO_REF:0000024 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Pias2 protein inhibitor of activated STAT, 2 IMP RGD PMID:9920921 RGD:70792 NCBI chr18:70,608,034...70,714,295
Ensembl chr18:70,607,665...70,710,033 		JBrowse link
G Rhoa ras homolog family member A acts_upstream_of_or_within ISO (PMID:16254014) RGD PMID:16254014 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746 		JBrowse link
G Rhox13 Rhox homeobox family member 13 involved_in ISO (PMID:11980563) RGD PMID:11980563 NCBI chr  X:116,911,226...116,917,758
Ensembl chr  X:116,911,329...116,917,644 		JBrowse link
G Rwdd1 RWD domain containing 1 involved_in ISO (PMID:18761815) RGD PMID:18761815 NCBI chr20:25,949,723...25,967,147
Ensembl chr20:25,941,966...25,967,193 		JBrowse link
G Scgb2a1 secretoglobin, family 2A, member 1 involved_in ISO
IBA		 (PMID:16020486)
GO_REF:0000033		 RGD
GO_Central		 PMID:16020486 GO_REF:0000033 NCBI chr 1:206,497,848...206,501,211
Ensembl chr 1:206,497,849...206,501,211
Ensembl chr 1:206,497,849...206,501,211 		JBrowse link
G Tmf1 TATA element modulatory factor 1 involved_in ISO (PMID:10428808) RGD PMID:10428808 NCBI chr 4:129,759,952...129,785,705
Ensembl chr 4:129,763,114...129,785,629 		JBrowse link
G Ube3a ubiquitin protein ligase E3A acts_upstream_of_or_within ISO PR:P19091 (PMID:16254014) RGD PMID:16254014 NCBI chr 1:110,070,260...110,161,675
Ensembl chr 1:110,070,480...110,157,250 		JBrowse link
G Zdhhc7 zinc finger DHHC-type palmitoyltransferase 7 involved_in ISO
IEA		 (PMID:22031296)
GO_REF:0000107		 RGD
Ensembl		 PMID:22031296 GO_REF:0000107 NCBI chr19:48,139,309...48,156,673
Ensembl chr19:48,139,527...48,156,673 		JBrowse link
G Zmiz1 zinc finger, MIZ-type containing 1 involved_in ISO (PMID:14609956) RGD PMID:14609956 NCBI chr16:1,027,083...1,232,616
Ensembl chr16:1,027,325...1,232,597 		JBrowse link
negative regulation of androgen receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dab2 DAB adaptor protein 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:16267015)		 Ensembl
RGD		 PMID:16267015 GO_REF:0000107 NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476 		JBrowse link
G Esr2 estrogen receptor 2 acts_upstream_of_or_within ISO MGI:2152217 (PMID:12370428) RGD PMID:12370428 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Foxh1 forkhead box H1 involved_in ISO (PMID:16120611) RGD PMID:16120611 NCBI chr 7:108,387,969...108,391,566
Ensembl chr 7:108,387,969...108,390,049 		JBrowse link
G Foxp1 forkhead box P1 involved_in ISO (PMID:18640093) RGD PMID:18640093 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258 		JBrowse link
G Hdac1 histone deacetylase 1 involved_in ISO (PMID:15919722) RGD PMID:15919722 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111 		JBrowse link
G Heyl hes-related family bHLH transcription factor with YRPW motif-like involved_in ISO (PMID:21454491) RGD PMID:21454491 NCBI chr 5:135,508,160...135,525,152
Ensembl chr 5:135,508,160...135,525,152 		JBrowse link
G Igf1 insulin-like growth factor 1 acts_upstream_of_or_within ISO MGI:2152423 (PMID:18827067) RGD PMID:18827067 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Ncor1 nuclear receptor co-repressor 1 involved_in ISO
IEA		 (PMID:20812024)
GO_REF:0000107		 RGD
Ensembl		 PMID:20812024 GO_REF:0000107 NCBI chr10:46,999,536...47,142,294
Ensembl chr10:46,999,536...47,141,032 		JBrowse link
G Ncor2 nuclear receptor co-repressor 2 involved_in ISO (PMID:20812024) RGD PMID:20812024 NCBI chr12:31,466,418...31,628,319
Ensembl chr12:31,466,412...31,628,319 		JBrowse link
G Nodal nodal growth differentiation factor involved_in ISO (PMID:21656830) RGD PMID:21656830 NCBI chr20:29,368,436...29,376,837
Ensembl chr20:29,368,436...29,376,837 		JBrowse link
G Phb1 prohibitin 1 involved_in ISO (PMID:16964284), (PMID:18487222) RGD PMID:16964284 PMID:18487222 NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042 		JBrowse link
G Pias2 protein inhibitor of activated STAT, 2 involved_in ISO
IEA		 (PMID:11477070)
GO_REF:0000107		 RGD
Ensembl		 PMID:11477070 GO_REF:0000107 NCBI chr18:70,608,034...70,714,295
Ensembl chr18:70,607,665...70,710,033 		JBrowse link
G Pten phosphatase and tensin homolog acts_upstream_of_or_within ISO MGI:2385927|MGI:2679886 (PMID:29057879) RGD PMID:29057879 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Sfrp1 secreted frizzled-related protein 1 involved_in ISO
IEA		 (PMID:19277043)
GO_REF:0000107		 RGD
Ensembl		 PMID:19277043 GO_REF:0000107 NCBI chr16:68,575,763...68,614,180
Ensembl chr16:68,575,763...68,614,286 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO
IEA		 (PMID:17505061)
GO_REF:0000107		 RGD
Ensembl		 PMID:17505061 GO_REF:0000107 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 involved_in ISO
IEA		 (PMID:18487222)
GO_REF:0000107		 RGD
Ensembl		 PMID:18487222 GO_REF:0000107 NCBI chr 8:20,167,717...20,258,975
Ensembl chr 8:20,167,717...20,258,975 		JBrowse link
G Tcf21 transcription factor 21 involved_in ISS
ISO		 GO_REF:0000024
(PMID:15919722)		 UniProt
RGD		 PMID:15919722 GO_REF:0000024 NCBI chr 1:22,701,353...22,704,212
Ensembl chr 1:22,701,353...22,704,202 		JBrowse link
G Zbtb7a zinc finger and BTB domain containing 7a involved_in ISO
ISS
IEA		 (PMID:20812024)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:20812024 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:8,561,015...8,578,243
Ensembl chr 7:8,563,779...8,576,539 		JBrowse link
regulation of androgen receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddx5 DEAD-box helicase 5 involved_in ISO (PMID:18829551) RGD PMID:18829551 NCBI chr10:91,723,508...91,732,210
Ensembl chr10:91,723,508...91,732,283 		JBrowse link
G Ep300 E1A binding protein p300 involved_in ISO (PMID:18487222) RGD PMID:18487222 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Foxp1 forkhead box P1 acts_upstream_of_or_within_positive_effect ISO MGI:109583|MGI:1919421 (PMID:29057879) RGD PMID:29057879 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258 		JBrowse link
G Kdm5d lysine demethylase 5D involved_in ISO (PMID:27185910) RGD PMID:27185910 NCBI chr  Y:527,069...624,019
Ensembl chr  Y:530,401...624,018 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISO
ISS		 (PMID:11477070)
GO_REF:0000024		 RGD
ParkinsonsUK-UCL		 PMID:11477070 GO_REF:0000024 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Pias2 protein inhibitor of activated STAT, 2 acts_upstream_of_or_within IDA PMID:9920921 MGI PMID:9920921 RGD:70792 NCBI chr18:70,608,034...70,714,295
Ensembl chr18:70,607,665...70,710,033 		JBrowse link
G Prmt2 protein arginine methyltransferase 2 involved_in ISO (PMID:17587566) RGD PMID:17587566 NCBI chr20:12,394,748...12,420,643
Ensembl chr20:12,394,798...12,420,643 		JBrowse link
G Rnf14 ring finger protein 14 involved_in ISO (PMID:19345326) RGD PMID:19345326 NCBI chr18:30,131,627...30,155,686
Ensembl chr18:30,131,691...30,155,685 		JBrowse link
G Rnf6 ring finger protein 6 involved_in ISO (PMID:19345326) RGD PMID:19345326 NCBI chr12:8,816,797...8,826,870
Ensembl chr12:8,816,833...8,826,847 		JBrowse link
G Safb2 scaffold attachment factor B2 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:5695073 (PMID:26092125)		 GO_Central
RGD		 PMID:26092125 GO_REF:0000033 NCBI chr 9:1,395,852...1,417,010
Ensembl chr 9:1,387,107...1,417,038 		JBrowse link
G Shq1 SHQ1, H/ACA ribonucleoprotein assembly factor acts_upstream_of_or_within_positive_effect ISO MGI:109583|MGI:1914004 (PMID:29057879) RGD PMID:29057879 NCBI chr 4:133,213,357...133,305,586
Ensembl chr 4:133,213,361...133,305,586 		JBrowse link
G Trim68 tripartite motif containing 68 involved_in ISO (PMID:18451177) RGD PMID:18451177 NCBI chr 1:157,114,044...157,127,494
Ensembl chr 1:157,114,044...157,127,477 		JBrowse link
G Usp26 ubiquitin specific peptidase 26 involved_in ISO (PMID:20501646) RGD PMID:20501646 NCBI chr  X:131,317,200...131,363,964
Ensembl chr  X:131,319,194...131,363,970 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20052
    cellular process 19130
      signal transduction 7170
        hormone-mediated signaling pathway 215
          steroid hormone receptor signaling pathway 136
            nuclear receptor-mediated steroid hormone signaling pathway 123
              androgen receptor signaling pathway 48
                negative regulation of androgen receptor signaling pathway 18
                positive regulation of androgen receptor signaling pathway 0
                regulation of androgen receptor signaling pathway + 29
Path 2
Term Annotations click to browse term
  biological_process 20052
    biological regulation 13542
      regulation of biological process 13122
        regulation of cellular process 12758
          signal transduction 7170
            intracellular signal transduction 3066
              intracellular receptor signaling pathway 391
                nuclear receptor-mediated signaling pathway 188
                  nuclear receptor-mediated steroid hormone signaling pathway 123
                    androgen receptor signaling pathway 48
                      negative regulation of androgen receptor signaling pathway 18
                      positive regulation of androgen receptor signaling pathway 0
                      regulation of androgen receptor signaling pathway + 29
paths to the root