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Gene:
Prkcb ( Rattus norvegicus )
protein kinase C, beta
Description:plays a role in hexosamine biosynthesis pathway induced transcriptional regulation
Synonyms:protein kinase C beta I; Protein kinase C beta; protein kinase C beta II; protein kinase C, beta 1; Pkcb; Prkcb1;  
ArrayIDs:5750588; E01789cds_s_at; 1368240_a_at; 5728248; 6600342; 1397189_at; 6344699; 6734923; 5909597; X04139_s_at; 6360444; 6150132; 6431484; 5938560; 6394613; 6392376; K03486_s_at; GE19917; 1370585_a_at; 5661149; 6479635; 6195721; 5982077; 5709827; 5836864; 5880191; 6729155;  (details...)
Gene Type:protein-coding
 
Additional Data
Markers: D1Smu9
 
Homologs
Homo sapiens: PRKCB     See the Human gene in context in:     UCSC     NCBI MapViewer
Mus musculus: Prkcb     See the Mouse gene in context in:     UCSC     NCBI MapViewer
 
Comparative Map Data
SpeciesSymbolMap NameChr.Position
Rattus norvegicusPrkcbgenome assembly 3.11181257931 - 181599763
  Rat Celera Assembly1174676982 - 174871327
  RGSC genome assembly v3.41181117515 - 181459856
  Cytogenetic1q36
Mus musculusPrkcbMouse genome assembly build 36.17129432639 - 129777916
  Cytogenetic77 F3
Homo sapiensPRKCBhuman genome assembly1623754822 - 24139063
  Human genome assembly build 36.21623754823 - 24139063
  Cytogenetic16p11.2
 
View comparative maps:      NCBI MapViewer
 
 Genome
View:
 
Browsers:
 
Other Map Data:
Associated SSLP Map Locations
No mapping information currently available in RGD for D1Smu9
 
 Annotation
Molecular Function
Gene Ontology
protein binding,  calcium channel regulator activity,  protein kinase C activity (details...)
Biological Process
Gene Ontology
cellular calcium ion homeostasis,  response to drug,  protein amino acid phosphorylation ...  (details...)
Cellular Component
Gene Ontology
nucleus,  soluble fraction,  cytoplasm ...  (details...)
Disease
Ontology
Diabetic Nephropathies,  Diabetes Mellitus, Experimental,  Myocardial Reperfusion Injury ...  (details...)
Phenotype
Ontology
immunodeficiency (details...)
Pathway
Ontology
vascular endothelial growth factor signaling pathway,  insulin signaling pathway (details...)
 
 External Links
Databases
DATABASEIDSOURCE
SMART:S_TKcIPI
SMART:S_TK_XIPI
SMART:C2IPI
SMART:C1IPI
PROSITE:ZF_DAG_PE_2IPI
PROSITE:ZF_DAG_PE_1IPI
PROSITE:PROTEIN_KINASE_STIPI
PROSITE:PROTEIN_KINASE_DOMIPI
PROSITE:PROTEIN_KINASE_ATPIPI
PROSITE:C2IPI
PROSITE:AGC_KINASE_CTERIPI
UNIPARC:UPI0000025B6BIPI
UNIPARC:UPI00000210CDIPI
KEGG Report:rno:25023ENTREZGENE
HomoloGene Group ID:56424ENTREZGENE
Germonline:3396
Pfam:Pkinase_CIPI
Pfam:PkinaseIPI
Pfam:C2IPI
Pfam:C1_1IPI
KEGG Pathway:04310ENTREZGENE
KEGG Pathway:04270ENTREZGENE
KEGG Pathway:04370ENTREZGENE
KEGG Pathway:04530ENTREZGENE
KEGG Pathway:04070ENTREZGENE
KEGG Pathway:05200ENTREZGENE
KEGG Pathway:05223ENTREZGENE
KEGG Pathway:04650ENTREZGENE
KEGG Pathway:04916ENTREZGENE
KEGG Pathway:04010ENTREZGENE
KEGG Pathway:04720ENTREZGENE
KEGG Pathway:04730ENTREZGENE
KEGG Pathway:04670ENTREZGENE
KEGG Pathway:04912ENTREZGENE
KEGG Pathway:05214ENTREZGENE
KEGG Pathway:04540ENTREZGENE
KEGG Pathway:04510ENTREZGENE
KEGG Pathway:04666ENTREZGENE
KEGG Pathway:04012ENTREZGENE
KEGG Pathway:04062ENTREZGENE
KEGG Pathway:04020ENTREZGENE
KEGG Pathway:04662ENTREZGENE
InterPro:Ser/Thr_prot_kinase_dom.IPI
InterPro:Ser/Thr_prot_kinase_AS.IPI
InterPro:Se/Thr_prot_kinase-like_dom.IPI
InterPro:Protein_kinase_C_a/b/g.IPI
InterPro:Protein_kinase_ATP_BS.IPI
InterPro:Prot_kinase_cat_dom.IPI
InterPro:Prot_Kinase_C-like_PE/DAG_bd.IPI
InterPro:Pkinase_C.IPI
InterPro:PKC.IPI
InterPro:Kinase-like_dom.IPI
InterPro:DAG/PE_bd.IPI
InterPro:C2_region.IPI
InterPro:C2_membr_targeting.IPI
InterPro:C2_Ca/lipid-bd_reg_CaLB.IPI
InterPro:C2_Ca-dep.IPI
InterPro:AGC-kinase_C.IPI
Ensembl Protein:ENSRNOP00000016442IPI
Ensembl Protein:ENSRNOP00000016417IPI
IPI:IPI00230864IPI
IPI:IPI00189278IPI
Entrez Gene:PrkcbENTREZGENE
PIRSF:PKC_alphaIPI
Ensembl Genes:ENSRNOG00000012061IPI
UniProt:KPCB_RATIPI
UniProt:Q6LDV0_RATIPI
UniProt:KPCB_RATIPI
RatMap:36403ENTREZGENE
Superfamily-SCOP:Kinase_likeIPI
Superfamily-SCOP:C2_CaLBIPI
PANTHER:PKCIPI
BIND:134040
PRINTS:DAGPEDOMAIN.IPI
PRINTS:C2DOMAIN.IPI
Sequences
Nucleotide:X04440Get FASTASearch GEO Profiles
Nucleotide:X04139Get FASTASearch GEO Profiles
Nucleotide:M19007Get FASTASearch GEO Profiles
Nucleotide:M15522Get FASTASearch GEO Profiles
Nucleotide:M13706Get FASTASearch GEO Profiles
Nucleotide:K03486Get FASTASearch GEO Profiles
Nucleotide:K03485Get FASTASearch GEO Profiles
Nucleotide:X04439Get FASTASearch GEO Profiles
Nucleotide:U62762Get FASTASearch GEO Profiles
Nucleotide:M16829Get FASTASearch GEO Profiles
Nucleotide:CH473956Get FASTASearch GEO Profiles
Nucleotide:XM_001079542Get FASTASearch GEO Profiles
Nucleotide:NM_012713Get FASTASearch GEO Profiles
(View all 13 Nucleotide Accessions)
Protein:Q6LDV0Get FASTA
Protein:P68403Get FASTA
Protein:CAA28036Get FASTA
Protein:CAA27756Get FASTA
Protein:AAA41868Get FASTA
Protein:AAA41876Get FASTA
Protein:AAA41875Get FASTA
Protein:AAA41865Get FASTA
Protein:AAA41864Get FASTA
Protein:CAA28035Get FASTA
Protein:AAA41869Get FASTA
Protein:EDM17557Get FASTA
Protein:EDM17556Get FASTA
Protein:EDM17555Get FASTA
Protein:EDM17554Get FASTA
Protein:XP_001079542Get FASTA
Protein:NP_036845Get FASTA
(View all 17 Protein Accessions)
Clusters
UniGene:91118
 
 References
Curated References
42 references in RGD related to Prkcb
Other References
63 other references at PubMed related to Prkcb
 
 Database Information
RGD ID3396
History
Date Current Symbol Current Name Previous Symbol Previous name Status Description Reference
24-OCT-08: Prkcb protein kinase C, beta Prkcb1 protein kinase C, beta 1 APPROVED Nomenclature updated to reflect human and mouse nomenclature 1299863
09-APR-03: Prkcb1 protein kinase C, beta 1 Protein kinase C beta APPROVED Name updated 629478
10-JUN-02: Prkcb1 Protein kinase C beta APPROVED Symbol and Name status set to approved 70586

       

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