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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3396 Species: Rattus norvegicus RGD Object: Gene Symbol: Prkcb Name: protein kinase C, beta

Acc ID: CHEBI:28834 Term: deoxycholic acid Definition: A dihydroxy-5beta-cholanic acid that has formula C24H40O4. CasRN: 83-44-3 Chemical ID: MESH:D003840

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	ISO	RGD:731404	6480464	CTD	Aspirin inhibits the reaction [Deoxycholic Acid results in increased expression of PRKCB protein] benzyloxycarbonyl-isoleucyl-glutamyl(O-tert-butyl)-alanyl-leucinal inhibits the reaction [Deoxycholic Acid results in increased expression of PRKCB protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Deoxycholic Acid results in increased expression of PRKCB protein] lactacystin inhibits the reaction [Deoxycholic Acid results in increased expression of PRKCB protein]	PMID:17644113
increases expression	ISO	RGD:731404	6480464	CTD	Deoxycholic Acid results in increased expression of PRKCB protein	PMID:17644113