Ppp2ca Rat Gene (protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform)

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Keyword

Gene:
Ppp2ca ( Rattus norvegicus )
protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform
Description: catalyzes the removal of serine- and threonine- bound phosphate groups
Synonyms: protein phosphatase 2a, catalytic subunit, alpha isoform; Protein phosphatase 2 (formerly 2A) catalytic subunit alpha isoform; Pp2a1;  (details...)
ArrayIDs: GE20296; 5732343; 1388805_at; 5652051; 1379616_at; 5902543; 5964025; rc_AI009467_at; 6588379; 6170595; 6390871; 6170287; rc_AI012595_at; 1398790_at; A_44_P273990; A_44_P268427; 5827507; 5698386; 5856220; 6576250; 6666953; X16043cds_at; A_44_P273989; 5994459; A_43_P11788; 5629572; 6320802; 5652164; 6288731; 6218306; rc_AI059014_f_at; GE22108;  (details...)
Gene Type: protein-coding

Additional Data

Homologs
Homo sapiens: PPP2CA     See the Human gene in context in:     UCSC     NCBI MapViewer

Mus musculus: Ppp2ca     See the Mouse gene in context in:     UCSC     NCBI MapViewer

Comparative Map Data
Species Symbol Map Name Chr. Position
Rattus norvegicus Ppp2ca genome assembly 3.1 10 37627685 - 37647436
Rat Celera Assembly 10 35713154 - 35732937
RGSC genome assembly v3.4 10 37621256 - 37641008
Cytogenetic 10 q22
Mus musculus Ppp2ca Mouse genome assembly build 36.1 11 51912326 - 51936251
Cytogenetic 11 11 B1.3
Homo sapiens PPP2CA human genome assembly 5 133560046 - 133589849
Human genome assembly build 36.2 5 133560047 - 133589849
Cytogenetic 5 q31.1

View comparative maps:      NCBI MapViewer

Genome
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Browsers:

Annotation
Molecular Function

Gene Ontology

iron ion binding,  protein heterodimerization activity,  metal ion binding ... (details...)
Biological Process

Gene Ontology

protein amino acid dephosphorylation,  mesoderm development (details...)
Cellular Component

Gene Ontology

nucleus,  chromosome, centromeric region,  protein phosphatase type 2A complex ... (details...)
Disease

Ontology

Prostatic Neoplasms (details...)

External Links
Databases
DATABASE ID SOURCE
SMART: PP2Ac IPI
PROSITE: SER_THR_PHOSPHATASE IPI
UNIPARC: UPI0000001861 IPI
KEGG Report: rno:24672 ENTREZGENE
HomoloGene Group ID: 37660 ENTREZGENE
Germonline: 3380
Pfam: Metallophos IPI
KEGG Pathway: 04350 ENTREZGENE
KEGG Pathway: 04730 ENTREZGENE
KEGG Pathway: 04530 ENTREZGENE
KEGG Pathway: 04310 ENTREZGENE
InterPro: M-pesterase. IPI
InterPro: Ser/Thr-sp_prot-phosphatase. IPI
Ensembl Protein: ENSRNOP00000007621 IPI
IPI: IPI00200391 IPI
Entrez Gene: Ppp2ca ENTREZGENE
IMAGE_CLONE: IMAGE:7096821 IMAGE-MGC_LOAD
IMAGE_CLONE: IMAGE:7104697 IMAGE-MGC_LOAD
MGC_CLONE: MGC:91734 IMAGE-MGC_LOAD
MGC_CLONE: MGC:91735 IMAGE-MGC_LOAD
UniProt: PP2AA_RAT IPI
Ensembl Genes: ENSRNOG00000005389 IPI
RatMap: 34317 ENTREZGENE
PANTHER: T_phtase_apaH IPI
PRINTS: STPHPHTASE. IPI
Sequences
Nucleotide: BC070914 Get FASTA Search GEO Profiles
Nucleotide: BC072531 Get FASTA Search GEO Profiles
Nucleotide: M33114 Get FASTA Search GEO Profiles
Nucleotide: CH473948 Get FASTA Search GEO Profiles
Nucleotide: X14159 Get FASTA Search GEO Profiles
Nucleotide: NM_017039 Get FASTA Search GEO Profiles
Nucleotide: X16043 Get FASTA Search GEO Profiles
(View all 7 Nucleotide Accessions)
Protein: EDM04352 Get FASTA
Protein: AAH72531 Get FASTA
Protein: EDM04351 Get FASTA
Protein: AAA41904 Get FASTA
Protein: NP_058735 Get FASTA
Protein: EDM04353 Get FASTA
Protein: CAA34166 Get FASTA
Protein: P63331 Get FASTA
Protein: AAH70914 Get FASTA
Protein: CAB42983 Get FASTA
(View all 10 Protein Accessions)
Clusters
UniGene: 1271

References
Curated References
7 references in RGD related to Ppp2ca

Other References
22 other references at PubMed related to Ppp2ca

Database Information
RGD ID 3380
History

Date Current Symbol Current Name Previous Symbol Previous name Status Description Reference

30-MAR-06: Ppp2ca protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform protein phosphatase 2a, catalytic subunit, alpha isoform APPROVED Name updated 1299863

10-JUN-02: Ppp2ca Protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform APPROVED Symbol and Name status set to approved 70586