GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ppp2ca | multiple interactions | ISO | Ppp2ca (Mus musculus) | 6480464 | CTD | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of PPP2CA mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of PPP2CA gene; Folic Acid deficiency promotes the reaction [Streptozocin results in decreased methylation of PPP2CA protein]; Folic Acid inhibits the reaction [Streptozocin results in decreased methylation of PPP2CA protein] | PMID:20938992 PMID:22206623 PMID:28422052 | |
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