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Pathways
Genes search result for Rattus norvegicus
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49 records found for search term Cdc42
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
71043Cdc42cell division cycle 42ENCODES a protein that exhibits GTP binding; mitogen-activated protein kinase kinase kinase binding; apolipoprotein A-I receptor binding (ortholog); INVOLVED IN actin filament branching; actin filament organization; establishment of Golgi localization; PARTICIPATES IN Rho/Rac/Cdc425154838478154876629Rat407symbol , PhenoGen , descriptiongene, protein-coding, PROVISIONAL [RefSeq]
41142645Cdc42-ps1cell division cycle 42, pseudogene 147117381871174534Ratsymbol , PhenoGengene, pseudo, MODEL [RefSeq]
1561700Cdc42se1CDC42 small effector 1ENCODES a protein that exhibits small GTPase binding (inferred); INVOLVED IN phagocytosis (inferred); regulation of cell shape (inferred); regulation of Rho protein signal transduction (inferred); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); FOUND IN cell junction (ortholog); INTERACTS W2185494692185502519Rat93symbol , old_gene_name , PhenoGen , namegene, protein-coding, PROVISIONAL [RefSeq]
1563924Cdc42se2CDC42 small effector 2ENCODES a protein that exhibits signaling adaptor activity (ortholog); INVOLVED IN regulation of signal transduction (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; alpha-Zearalanol; bisphenol A103933726939405772Rat77symbol , old_gene_name , PhenoGen , namegene, protein-coding, VALIDATED [RefSeq]
1311131Cdc42ep1CDC42 effector protein 1INVOLVED IN positive regulation of pseudopodium assembly (ortholog); regulation of cell shape (ortholog); Rho protein signal transduction (ortholog); FOUND IN actin cytoskeleton (ortholog); cytoplasm (ortholog); plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-27112275759112283665Rat117symbol , old_gene_name , PhenoGen , namegene, protein-coding, PROVISIONAL [RefSeq]
1310253Cdc42ep2CDC42 effector protein 2ENCODES a protein that exhibits GTPase activator activity (ortholog); opioid peptide activity (ortholog); small GTPase binding (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); cellular response to type II interferon (ortholog); positive regulation of actin filament polymerization 1212631317212640231Rat124symbol , old_gene_name , PhenoGen , namegene, protein-coding, PROVISIONAL [RefSeq]
1305858Cdc42ep3CDC42 effector protein 3FOUND IN actin cytoskeleton (ortholog); plasma membrane (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine62146308121483553Rat134symbol , old_gene_name , PhenoGen , namegene, protein-coding, VALIDATED [RefSeq]
1311567Cdc42ep4CDC42 effector protein 4INVOLVED IN cellular response to type II interferon (ortholog); positive regulation of pseudopodium assembly (ortholog); regulation of cell shape (ortholog); FOUND IN actin cytoskeleton (ortholog); adherens junction (ortholog); cytoplasm (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlo109927175099298551Rat123symbol , old_gene_name , PhenoGen , namegene, protein-coding, PROVISIONAL [RefSeq]
1308382Cdc42ep5CDC42 effector protein 5ENCODES a protein that exhibits small GTPase binding (ortholog); INVOLVED IN JNK cascade (ortholog); positive regulation of actin filament polymerization (ortholog); positive regulation of pseudopodium assembly (ortholog); FOUND IN cytoplasm (ortholog); membrane (ortholog); plasma membrane (ortholog17910803679110550Rat101symbol , old_gene_name , PhenoGen , namegene, protein-coding, VALIDATED [RefSeq]
621753Cdc42bpbCDC42 binding protein kinase betaENCODES a protein that exhibits protein serine/threonine kinase activity; small GTPase binding; ATP binding (ortholog); INVOLVED IN actin cytoskeleton organization; actomyosin structure organization; cell migration; ASSOCIATED WITH autism spectrum disorder (ortholog); Chilton-Okur-Chung neurodevelop6136154905136241259Rat156symbol , old_gene_name , PhenoGen , namegene, protein-coding, VALIDATED [RefSeq]
621406Cdc42bpaCDC42 binding protein kinase alphaENCODES a protein that exhibits ATP binding; identical protein binding; magnesium ion binding; INVOLVED IN actin cytoskeleton organization; actomyosin structure organization; cell migration; ASSOCIATED WITH COVID-19 (ortholog); FOUND IN actomyosin; cell leading edge; cell-cell junction; INTERACTS WI139421535994435681Rat161symbol , old_gene_name , PhenoGen , namegene, protein-coding, VALIDATED [RefSeq]
1307260Cdc42bpgCDC42 binding protein kinase gammaENCODES a protein that exhibits ATP binding (ortholog); magnesium ion binding (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN protein phosphorylation (ortholog); FOUND IN cell leading edge (ortholog); cytosol (ortholog); INTERACTS WITH acrylamide; alpha-Zearalanol; amphe1213037603213057764Rat93symbol , old_gene_name , PhenoGen , namegene, protein-coding, VALIDATED [RefSeq]
41095357Cdc42se1-ps1CDC42 small effector 1, pseudogene 15144646762144648633Ratsymbol , old_gene_name , PhenoGen , namegene, pseudo, MODEL [RefSeq]
2318957Cdc42se2-ps1CDC42 small effector 2, pseudogene 11100424071100427058Ratsymbol , old_gene_name , PhenoGen , namegene, pseudo, INFERRED [RefSeq]
620719Arhgef9Cdc42 guanine nucleotide exchange factor 9ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); INVOLVED IN receptor clustering; regulation of postsynaptic specialization assembly (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); developmental and epileptic encephX6392916864087267Rat118old_gene_name , namegene, protein-coding, VALIDATED [RefSeq]
1359674Arhgef6Rac/Cdc42 guanine nucleotide exchange factor 6ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); INVOLVED IN lamellipodium assembly (ortholog); PARTICIPATES IN ceramide signaling pathway; pancreatic cancer pathway; ASSOCIATED WITH autistic disorder (ortholog); intellectual disability (ortholog); LeukoencephalX140182734140302812Rat123old_gene_name , namegene, protein-coding, VALIDATED [RefSeq]
1305386Fnbp1lformin binding protein 1-likeENCODES a protein that exhibits GTPase binding (ortholog); INVOLVED IN cilium assembly (ortholog); clathrin-dependent endocytosis (ortholog); membrane invagination (ortholog); ASSOCIATED WITH basal cell carcinoma (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic vesicle (ortholog); cytosol (ort2213331871213432821Rat150old_gene_namegene, protein-coding, VALIDATED [RefSeq]
1305957Tnk2tyrosine kinase, non-receptor, 2ENCODES a protein that exhibits protein tyrosine kinase activity; epidermal growth factor receptor binding (ortholog); identical protein binding (ortholog); INVOLVED IN phosphorylation (ortholog); positive regulation of peptidyl-tyrosine phosphorylation (ortholog); regulation of clathrin-dependent e118161979581659074Rat164old_gene_namegene, protein-coding, VALIDATED [RefSeq]
735210Arhgef25Rho guanine nucleotide exchange factor 25ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); ASSOCIATED WITH prostate cancer (ortholog); FOUND IN myofibril (ortholog); plasma membrane (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine76489126064898382Rat80old_gene_namegene, protein-coding, VALIDATED [RefSeq]
621145Trip10thyroid hormone receptor interactor 10ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN epithelial to mesenchymal transition; negative regulation of cardiac muscle cell apoptotic process; positive regulation of cell growth involved in cardiac muscle cell development; PARTICIPATES IN insulin responsive fac922196952234771Rat97old_gene_namegene, protein-coding, VALIDATED [RefSeq]
1306093Arhgap31Rho GTPase activating protein 31ENCODES a protein that exhibits GTPase activator activity (ortholog); SH3 domain binding (ortholog); INVOLVED IN small GTPase-mediated signal transduction (ortholog); ASSOCIATED WITH Adams-Oliver syndrome (ortholog); Adams-Oliver Syndrome 1 (ortholog); cerebral palsy (ortholog); FOUND IN lamellipodi117554417675657087Rat98old_gene_namegene, protein-coding, PROVISIONAL [RefSeq]
3250Pak1p21 (RAC1) activated kinase 1ENCODES a protein that exhibits protein kinase activity; protein kinase binding; protein serine/threonine kinase activity; INVOLVED IN cellular response to insulin stimulus; cerebellum development; establishment of cell polarity; PARTICIPATES IN adenosine signaling pathway; ephrin - ephrin receptor 1161522399161637623Rat339old_gene_namegene, protein-coding, VALIDATED [RefSeq]
61953Pak2p21 (RAC1) activated kinase 2ENCODES a protein that exhibits identical protein binding (ortholog); protein kinase activity (ortholog); protein kinase binding (ortholog); INVOLVED IN cardiac muscle hypertrophy; cellular response to transforming growth factor beta stimulus; adherens junction assembly (ortholog); PARTICIPATES IN v118221289682273803Rat210old_gene_namegene, protein-coding, VALIDATED [RefSeq]
3251Pak3p21 (RAC1) activated kinase 3ENCODES a protein that exhibits GTPase binding; protein kinase activity; protein serine/threonine kinase activity; INVOLVED IN positive regulation of dendritic spine morphogenesis; positive regulation of DNA biosynthetic process; positive regulation of fibroblast migration; PARTICIPATES IN epidermalX111912967112171037Rat176old_gene_namegene, protein-coding, VALIDATED [RefSeq]
1307705Pak4p21 (RAC1) activated kinase 4ENCODES a protein that exhibits protein kinase activity (ortholog); protein serine kinase activity (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN dendritic spine development (ortholog); negative regulation of endothelial cell apoptotic process (ortholog); negative regul19297743793016721Rat129old_gene_namegene, protein-coding, PROVISIONAL [RefSeq]
1312009Pak5p21 (RAC1) activated kinase 5ENCODES a protein that exhibits protein serine/threonine kinase activity (ortholog); INVOLVED IN learning (ortholog); locomotory behavior (ortholog); memory (ortholog); PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; renal cell carcinoma pathway; T cell receptor signaling pathw3143848404144156674Rat83old_gene_namegene, protein-coding, VALIDATED [RefSeq]
1306213Pak6p21 (RAC1) activated kinase 6ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); nucleotide binding (inferred); INVOLVED IN learning (ortholog); locomotory behavior (ortholog); memory (ortholog); PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; renal cell carcinoma pathway; T3126092576126128320Rat116old_gene_namegene, protein-coding, VALIDATED [RefSeq]
629617Dock9dedicator of cytokinesis 9ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); small GTPase binding (ortholog); INVOLVED IN positive regulation of GTPase activity (ortholog); FOUND IN endomembrane system (inferred); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-15105018341105289799Rat123old_gene_namegene, protein-coding, VALIDATED [RefSeq]
1597791Ccdc160coiled-coil domain containing 160ASSOCIATED WITH genetic disease (ortholog); INTERACTS WITH bisphenol A; gentamycin; 17beta-hydroxy-5alpha-androstan-3-one (ortholog)X137389066137399452Rat24old_gene_namegene, protein-coding, VALIDATED [RefSeq]
2059Adrb1adrenoceptor beta 1ENCODES a protein that exhibits amine binding; beta1-adrenergic receptor activity; alpha-2A adrenergic receptor binding (ortholog); INVOLVED IN G protein-coupled receptor signaling pathway; glycogen catabolic process; inhibitory postsynaptic potential; PARTICIPATES IN Rho/Rac/Cdc421265777103265780114Rat424descriptiongene, protein-coding, VALIDATED [RefSeq]
619814Baiap2BAR/IMD domain containing adaptor protein 2ENCODES a protein that exhibits PDZ domain binding; scaffold protein binding; transcription coregulator binding; INVOLVED IN cellular response to epidermal growth factor stimulus; cellular response to L-glutamate; neuron differentiation; PARTICIPATES IN insulin responsive facilitative sugar transpor10105721371105788549Rat236descriptiongene, protein-coding, PROVISIONAL [RefSeq]
1310332Cyfip1cytoplasmic FMR1 interacting protein 1ENCODES a protein that exhibits RNA 7-methylguanosine cap binding; small GTPase binding (ortholog); translation repressor activity (ortholog); INVOLVED IN cellular response to insulin stimulus; negative regulation of synaptic vesicle recycling; positive regulation of axon extension; PARTICIPATES IN 1115842754115935163Rat150descriptiongene, protein-coding, PROVISIONAL [RefSeq]
68416Dlc1DLC1 Rho GTPase activating proteinENCODES a protein that exhibits GTPase activator activity; phospholipase binding; phospholipase C activator activity; INVOLVED IN cellular response to insulin stimulus; actin cytoskeleton organization (ortholog); focal adhesion assembly (ortholog); PARTICIPATES IN Rho/Rac/Cdc42166195417762374819Rat213descriptiongene, protein-coding, VALIDATED [RefSeq]
13830868Dock8m1Ztmdedicator of cytokinesis 8;mutant 1, ZtmASSOCIATED WITH type 1 diabetes mellitusRat1descriptiongene, allele
2535Ednraendothelin receptor type AENCODES a protein that exhibits endothelin receptor activity; INVOLVED IN cellular response to mechanical stimulus; fibroblast proliferation; glomerular filtration; PARTICIPATES IN endothelin signaling pathway; inflammatory response pathway; Rho/Rac/Cdc42 mediat194713736047207961Rat506descriptiongene, protein-coding, VALIDATED [RefSeq]
1560614Flnafilamin AENCODES a protein that exhibits protein-containing complex binding; SMAD binding; actin filament binding (ortholog); INVOLVED IN cerebral cortex development; establishment of Sertoli cell barrier; formation of radial glial scaffolds; PARTICIPATES IN calcium signaling pathway via the calcium-sensing X157159051157185559Rat459descriptiongene, protein-coding, VALIDATED [RefSeq]
2943JunJun proto-oncogene, AP-1 transcription factor subunitENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor activity; double-stranded DNA binding; INVOLVED IN angiogenesis; cellular response to hypoxia; cellular response to potassium ion starvation; PARTICIPATES IN Rho5115009900115012993Rat1797descriptiongene, protein-coding, VALIDATED [RefSeq]
62056Limk2LIM domain kinase 2ENCODES a protein that exhibits protein serine/threonine kinase activity; protein kinase activity (ortholog); INVOLVED IN protein phosphorylation; astral microtubule organization (ortholog); cornea development in camera-type eye (ortholog); PARTICIPATES IN Rho/Rac/Cdc42148238425682509755Rat158descriptiongene, protein-coding, VALIDATED [RefSeq]
1307040Map2k4mitogen activated protein kinase kinase 4ENCODES a protein that exhibits JUN kinase kinase activity; MAP kinase kinase activity; molecular adaptor activity (ortholog); INVOLVED IN cell growth involved in cardiac muscle cell development; cellular response to sorbitol; JNK cascade; PARTICIPATES IN c-Jun N-terminal kinases MAPK signaling path105084234850947063Rat261descriptiongene, protein-coding, VALIDATED [RefSeq]
621506Mapk8mitogen-activated protein kinase 8ENCODES a protein that exhibits JUN kinase activity; kinesin binding; enzyme binding (ortholog); INVOLVED IN cellular response to amyloid-beta; cellular response to interleukin-1; cellular response to oxygen-glucose deprivation; PARTICIPATES IN c-Jun N-terminal kinases MAPK signaling pathway; inflam1686451718728225Rat1586descriptiongene, protein-coding, REVIEWED [RefSeq]
619809Ntn1netrin 1INVOLVED IN Cdc42 protein signal transduction; positive regulation of axon extension; positive regulation of cell motility; ASSOCIATED WITH Oxygen-Induced Retinopathy; Alzheimer's disease (ortholog); brain edema (ortholog); FOUND IN basement membrane (ortholog);105339885253597595Rat173descriptiongene, protein-coding, VALIDATED [RefSeq]
1310790Plekhg4pleckstrin homology and RhoGEF domain containing G4ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; Rho/Rac/Cdc42 mediated signaling pathway; ASSOCIATED WITH spinocerebellar195016172250176491Rat78descriptiongene, protein-coding, VALIDATED [RefSeq]
68415Ppp5cprotein phosphatase 5, catalytic subunitENCODES a protein that exhibits G-protein alpha-subunit binding; heat shock protein binding; Hsp70 protein binding; INVOLVED IN cellular response to cadmium ion; cellular response to hydrogen peroxide; negative regulation of apoptotic process; PARTICIPATES IN Rho/Rac/Cdc4218681829786842505Rat197descriptiongene, protein-coding, PROVISIONAL [RefSeq]
1306534Prex1phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1ENCODES a protein that exhibits phospholipid binding (ortholog); INVOLVED IN positive regulation of cell migration; regulation of actin filament polymerization; regulation of dendrite development; PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; R3175724939175875764Rat158descriptiongene, protein-coding, PROVISIONAL [RefSeq]
628758Ptk2bprotein tyrosine kinase 2 betaENCODES a protein that exhibits 3-phosphoinositide-dependent protein kinase binding; calcium/calmodulin-dependent protein kinase activity; enzyme binding; INVOLVED IN actin filament organization; activation of GTPase activity; activation of Janus kinase activity; PARTICIPATES IN Jak-Stat signaling p154453627544656754Rat446descriptiongene, protein-coding, PROVISIONAL [RefSeq]
619755Rac1Rac family small GTPase 1ENCODES a protein that exhibits ATPase binding; GTP binding; GTPase activity; INVOLVED IN actin cytoskeleton organization; actin filament organization; bone resorption; PARTICIPATES IN Rho/Rac/Cdc42 mediated signaling pathway; Arf family mediated signaling pathw121615041116170864Rat639descriptiongene, protein-coding, PROVISIONAL [RefSeq]
621626Rhoqras homolog family member QENCODES a protein that exhibits GBD domain binding (ortholog); GTPase activity (ortholog); profilin binding (ortholog); INVOLVED IN cellular response to insulin stimulus (ortholog); cortical actin cytoskeleton organization (ortholog); GTP metabolic process (ortholog); PARTICIPATES IN insulin respons61336849913403929Rat167descriptiongene, protein-coding, VALIDATED [RefSeq]
1311558Shtn1shootin 1ENCODES a protein that exhibits actin filament binding; cell adhesion molecule binding; identical protein binding (ortholog); INVOLVED IN actin filament bundle retrograde transport; axonogenesis; Cdc42 protein signal transduction; FOUND IN axonal growth cone; fi1268108095268211947Rat152descriptiongene, protein-coding, VALIDATED [RefSeq]
1586598Sorbs1sorbin and SH3 domain containing 1ENCODES a protein that exhibits insulin receptor binding; ubiquitin protein ligase binding; protein kinase binding (ortholog); INVOLVED IN response to activity; response to insulin; response to L-glutamate; PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport 1249057324249279703Rat240descriptiongene, protein-coding, VALIDATED [RefSeq]