Gene: Pak3 (p21 protein (Cdc42/Rac)-activated kinase 3)  Rattus norvegicus

Symbol: Pak3
Name: p21 protein (Cdc42/Rac)-activated kinase 3
Description: ENCODES a protein that exhibits GTPase binding; protein kinase activity; MAP kinase kinase activity (ortholog); INVOLVED IN activation of MAPK activity (ortholog); axonogenesis (ortholog); dendrite development (ortholog); PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; renal cell cancer pathway; T cell receptor signaling pathway; ASSOCIATED WITH Mental Retardation, X-Linked (ortholog); Mental Retardation, X-Linked 30 (ortholog); FOUND IN cytoplasm (inferred); INTERACTS WITH C60 fullerene; chlorpyrifos; Delta(9)-tetrahydrocannabinol
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: beta-PAK; beta-PAK; p21 (CDKN1A)-activated kinase 3; p21-activated kinase 3; p21/Cdc42/Rac1-activated kinase 3 (yeast Ste20-related); p65-PAK; PAK-3; serine/threonine-protein kinase PAK 3
Orthologs: Homo sapiens : PAK3 (p21 protein (Cdc42/Rac)-activated kinase 3)  HGNC
Mus musculus : Pak3 (p21 protein (Cdc42/Rac)-activated kinase 3)  MGI
Latest Assembly: RGSC Genome Assembly v3.4
Position:
MapChrPositionStrandSource
Rat Cytogenetic MapXq14 NCBI
RGSC Genome Assembly v5.0X113,372,070 - 113,489,867+NCBI
RGSC Genome Assembly v3.4X34,734,814 - 34,842,093-NCBI
Rat Celera AssemblyX106,660,352 - 106,767,478+NCBI
Genome Assembly 3.1X34,788,282 - 34,895,562-NCBI
Model

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Pak3
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Ensembl Gene
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RGD Object Information
RGD ID: 3251
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2013-04-16
Status: ACTIVE