Gene: Prex1 (phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1) Rattus norvegicus
Analyze
Symbol: Prex1
Name: phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
Description: ENCODES a protein that exhibits phospholipid binding (ortholog); INVOLVED IN positive regulation of cell migration; regulation of actin filament polymerization; regulation of dendrite development; PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; Rho/Rac/Cdc42 mediated signaling pathway; chemokine mediated signaling pathway; ASSOCIATED WITH Lymphatic Metastasis (ortholog); Prostatic Neoplasms (ortholog); FOUND IN dendritic shaft; growth cone; perinuclear region of cytoplasm; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; bis(2-chloroethyl) sulfide; bisphenol A
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC311647; phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein; RGD1306534; similar to P-Rex1
Orthologs:
Allele / Splice: Prex1em2Mcwi  
Genetic Models: SS-Prex1em2Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03163,329,580 - 163,477,822 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03169,494,331 - 169,575,981 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43157,693,897 - 157,863,943 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13157,599,463 - 157,770,600 (-)NCBI
Celera3153,891,483 - 154,040,542 (-)NCBICelera
Cytogenetic Map3q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Prex1
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1306534
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE