Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

Ontology Browser
Term:
Parent Terms Term With Siblings Child Terms
aldosterone signaling pathway   
altered sex steroids signaling pathway +    
altered transcription factor mediated signaling pathway +    
altered transcription pathway via transcription factor mediated signaling +    
androgen signaling pathway +     
Androgens are C19 steroids that constitutes the male sex hormones. They are also the precursors of female sex hormones, the estrogens. Testosterone and its more potent metabolite, dihydrotestosterone bind to androgen receptors to then translocate to the nucleus and activate the transcription of target genes. Many regulators, both activators and repressors, have been identified. Upregulation of receptor activity has been implicated in prostate cancer.
View Interactive Diagram
basic helix-loop-helix signaling pathway +    
bile acid signaling pathway  
cortisol signaling pathway +    
estrogen signaling pathway +    
forkhead signaling pathway +   
hypoxia inducible factor pathway +     
nuclear factor kappa B signaling pathway +    
nuclear factor of activated T-cells signaling pathway  
nuclear factor, erythroid 2 like 2 signaling pathway +    
p53 signaling pathway +     
peroxisome proliferator-activated receptor signaling pathway +  
retinoic acid signaling pathway   
sterol regulatory element-binding protein signaling pathway   
vitamin D signaling pathway 

Synonyms
Related Synonyms: PID:200105
Definition Sources: PMID:17163421, PMID:18657355

paths to the root