Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:glioma pathway
go back to main search page
Accession:PW:0000711 term browser browse the term
Definition:Gliomas are tumors of the brain categorized by the type of cell they are associated with, their location and grade. Several pathways appear to be deregulated via amplifications, overexpression, mutations or loss.
Synonyms:related_synonym: KEGG:05214


show annotations for term's descendants           Sort by:
glioma pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 IEA KEGG hsa:05214 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759 		JBrowse link
G AKT2 AKT serine/threonine kinase 2 IEA KEGG hsa:05214 NCBI chr19:40,230,317...40,285,345
Ensembl chr19:40,230,317...40,285,536 		JBrowse link
G AKT3 AKT serine/threonine kinase 3 IEA KEGG hsa:05214 NCBI chr 1:243,488,233...243,851,079
Ensembl chr 1:243,488,233...243,851,079 		JBrowse link
G ARAF A-Raf proto-oncogene, serine/threonine kinase IEA KEGG hsa:05214 NCBI chr  X:47,561,205...47,571,908
Ensembl chr  X:47,561,205...47,571,908 		JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase IEA KEGG hsa:05214 NCBI chr 7:140,713,328...140,924,929
Ensembl chr 7:140,719,327...140,924,929 		JBrowse link
G CALM1 calmodulin 1 IEA KEGG hsa:05214 NCBI chr14:90,396,502...90,408,268
Ensembl chr14:90,396,502...90,408,268 		JBrowse link
G CALM2 calmodulin 2 IEA KEGG hsa:05214 NCBI chr 2:47,160,082...47,176,936
Ensembl chr 2:47,160,084...47,176,921 		JBrowse link
G CALM3 calmodulin 3 IEA KEGG hsa:05214 NCBI chr19:46,601,074...46,610,782
Ensembl chr19:46,601,074...46,610,782 		JBrowse link
G CALML3 calmodulin like 3 IEA KEGG hsa:05214 NCBI chr10:5,524,961...5,526,771
Ensembl chr10:5,524,961...5,526,771 		JBrowse link
G CALML5 calmodulin like 5 IEA KEGG hsa:05214 NCBI chr10:5,498,697...5,499,570
Ensembl chr10:5,498,697...5,499,570 		JBrowse link
G CALML6 calmodulin like 6 IEA KEGG hsa:05214 NCBI chr 1:1,915,260...1,917,296
Ensembl chr 1:1,915,108...1,917,296 		JBrowse link
G CAMK2A calcium/calmodulin dependent protein kinase II alpha IEA KEGG hsa:05214 NCBI chr 5:150,219,491...150,290,130
Ensembl chr 5:150,219,491...150,290,093 		JBrowse link
G CAMK2B calcium/calmodulin dependent protein kinase II beta IEA KEGG hsa:05214 NCBI chr 7:44,217,154...44,326,013
Ensembl chr 7:44,210,019...44,334,577 		JBrowse link
G CAMK2D calcium/calmodulin dependent protein kinase II delta IEA KEGG hsa:05214 NCBI chr 4:113,451,032...113,761,738
Ensembl chr 4:113,418,054...113,761,927 		JBrowse link
G CAMK2G calcium/calmodulin dependent protein kinase II gamma IEA KEGG hsa:05214 NCBI chr10:73,812,501...73,874,555
Ensembl chr10:73,812,501...73,874,591 		JBrowse link
G CCND1 cyclin D1 IEA KEGG hsa:05214 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474 		JBrowse link
G CDK4 cyclin dependent kinase 4 IEA KEGG hsa:05214 NCBI chr12:57,747,727...57,752,310
Ensembl chr12:57,747,727...57,756,013 		JBrowse link
G CDK6 cyclin dependent kinase 6 IEA KEGG hsa:05214 NCBI chr 7:92,604,921...92,836,573
Ensembl chr 7:92,604,921...92,836,573 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A IEA KEGG hsa:05214 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337 		JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A IEA KEGG hsa:05214 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301 		JBrowse link
G E2F1 E2F transcription factor 1 IEA KEGG hsa:05214 NCBI chr20:33,675,477...33,686,385
Ensembl chr20:33,675,477...33,686,385 		JBrowse link
G E2F2 E2F transcription factor 2 IEA KEGG hsa:05214 NCBI chr 1:23,505,212...23,531,233
Ensembl chr 1:23,506,438...23,531,233 		JBrowse link
G E2F3 E2F transcription factor 3 IEA KEGG hsa:05214 NCBI chr 6:20,401,879...20,493,714
Ensembl chr 6:20,401,879...20,493,714 		JBrowse link
G EGF epidermal growth factor IEA KEGG hsa:05214 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766 		JBrowse link
G EGFR epidermal growth factor receptor IEA KEGG hsa:05214 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G GRB2 growth factor receptor bound protein 2 IEA KEGG hsa:05214 NCBI chr17:75,318,076...75,405,678
Ensembl chr17:75,318,076...75,405,709 		JBrowse link
G HRAS HRas proto-oncogene, GTPase IEA KEGG hsa:05214 NCBI chr11:532,242...535,576
Ensembl chr11:532,242...537,321 		JBrowse link
G IGF1 insulin like growth factor 1 IEA KEGG hsa:05214 NCBI chr12:102,395,874...102,481,839
Ensembl chr12:102,395,874...102,481,744 		JBrowse link
G IGF1R insulin like growth factor 1 receptor IEA KEGG hsa:05214 NCBI chr15:98,648,539...98,964,530
Ensembl chr15:98,648,539...98,964,530 		JBrowse link
G KRAS KRAS proto-oncogene, GTPase IEA KEGG hsa:05214 NCBI chr12:25,205,246...25,250,929
Ensembl chr12:25,205,246...25,250,936 		JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 IEA KEGG hsa:05214 NCBI chr15:66,386,912...66,491,544
Ensembl chr15:66,386,837...66,491,656 		JBrowse link
G MAP2K2 mitogen-activated protein kinase kinase 2 IEA KEGG hsa:05214 NCBI chr19:4,090,321...4,124,122
Ensembl chr19:4,090,321...4,124,122 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 IEA KEGG hsa:05214 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 IEA KEGG hsa:05214 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MDM2 MDM2 proto-oncogene IEA KEGG hsa:05214 NCBI chr12:68,808,172...68,850,686
Ensembl chr12:68,808,177...68,845,544 		JBrowse link
G MTOR mechanistic target of rapamycin kinase IEA KEGG hsa:05214 NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556 		JBrowse link
G NRAS NRAS proto-oncogene, GTPase IEA KEGG hsa:05214 NCBI chr 1:114,704,469...114,716,771
Ensembl chr 1:114,704,469...114,716,771 		JBrowse link
G PDGFA platelet derived growth factor subunit A IEA KEGG hsa:05214 NCBI chr 7:497,258...520,700
Ensembl chr 7:497,258...520,296 		JBrowse link
G PDGFB platelet derived growth factor subunit B IEA KEGG hsa:05214 NCBI chr22:39,223,359...39,244,982
Ensembl chr22:39,223,359...39,244,982 		JBrowse link
G PDGFRA platelet derived growth factor receptor alpha IEA KEGG hsa:05214 NCBI chr 4:54,229,293...54,298,245
Ensembl chr 4:54,229,280...54,298,245 		JBrowse link
G PDGFRB platelet derived growth factor receptor beta IEA KEGG hsa:05214 NCBI chr 5:150,113,839...150,155,845
Ensembl chr 5:150,113,839...150,155,872 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha IEA KEGG hsa:05214 NCBI chr 3:179,148,126...179,240,093
Ensembl chr 3:179,148,114...179,240,093 		JBrowse link
G PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta IEA KEGG hsa:05214 NCBI chr 3:138,652,698...138,834,928
Ensembl chr 3:138,652,698...138,834,928 		JBrowse link
G PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta IEA KEGG hsa:05214 NCBI chr 1:9,627,258...9,729,114
Ensembl chr 1:9,629,889...9,729,114 		JBrowse link
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma IEA KEGG hsa:05214 NCBI chr 7:106,865,282...106,908,980
Ensembl chr 7:106,865,278...106,908,980 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 IEA KEGG hsa:05214 NCBI chr 5:68,215,756...68,301,821
Ensembl chr 5:68,215,740...68,301,821 		JBrowse link
G PIK3R2 phosphoinositide-3-kinase regulatory subunit 2 IEA KEGG hsa:05214 NCBI chr19:18,153,163...18,170,532
Ensembl chr19:18,153,163...18,170,532 		JBrowse link
G PIK3R3 phosphoinositide-3-kinase regulatory subunit 3 IEA KEGG hsa:05214 NCBI chr 1:46,040,140...46,174,901
Ensembl chr 1:46,040,140...46,133,036 		JBrowse link
G PIK3R5 phosphoinositide-3-kinase regulatory subunit 5 IEA KEGG hsa:05214 NCBI chr17:8,878,916...8,965,707
Ensembl chr17:8,878,911...8,965,712 		JBrowse link
G PLCG1 phospholipase C gamma 1 IEA KEGG hsa:05214 NCBI chr20:41,137,543...41,177,626
Ensembl chr20:41,136,960...41,196,801 		JBrowse link
G PLCG2 phospholipase C gamma 2 IEA KEGG hsa:05214 NCBI chr16:81,779,291...81,962,685
Ensembl chr16:81,779,279...81,962,685 		JBrowse link
G PRKCA protein kinase C alpha IEA KEGG hsa:05214 NCBI chr17:66,302,613...66,810,743
Ensembl chr17:66,302,613...66,810,743 		JBrowse link
G PRKCB protein kinase C beta IEA KEGG hsa:05214 NCBI chr16:23,835,983...24,220,611
Ensembl chr16:23,835,983...24,220,611 		JBrowse link
G PRKCG protein kinase C gamma IEA KEGG hsa:05214 NCBI chr19:53,881,094...53,907,652
Ensembl chr19:53,879,190...53,907,652 		JBrowse link
G PTEN phosphatase and tensin homolog IEA KEGG hsa:05214 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930 		JBrowse link
G RAF1 Raf-1 proto-oncogene, serine/threonine kinase IEA KEGG hsa:05214 NCBI chr 3:12,583,601...12,664,117
Ensembl chr 3:12,582,101...12,664,201 		JBrowse link
G RB1 RB transcriptional corepressor 1 IEA KEGG hsa:05214 NCBI chr13:48,303,751...48,481,890
Ensembl chr13:48,303,744...48,599,436 		JBrowse link
G SHC1 SHC adaptor protein 1 IEA KEGG hsa:05214 NCBI chr 1:154,962,298...154,974,376
Ensembl chr 1:154,962,298...154,974,395 		JBrowse link
G SHC2 SHC adaptor protein 2 IEA KEGG hsa:05214 NCBI chr19:416,589...461,033
Ensembl chr19:416,589...461,033 		JBrowse link
G SHC3 SHC adaptor protein 3 IEA KEGG hsa:05214 NCBI chr 9:89,005,771...89,178,818
Ensembl chr 9:89,005,771...89,178,818 		JBrowse link
G SHC4 SHC adaptor protein 4 IEA KEGG hsa:05214 NCBI chr15:48,823,741...48,963,919
Ensembl chr15:48,823,741...48,963,919 		JBrowse link
G SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 IEA KEGG hsa:05214 NCBI chr 2:38,981,549...39,124,868
Ensembl chr 2:38,962,206...39,124,345 		JBrowse link
G SOS2 SOS Ras/Rho guanine nucleotide exchange factor 2 IEA KEGG hsa:05214 NCBI chr14:50,117,130...50,231,882
Ensembl chr14:50,117,130...50,231,578 		JBrowse link
G TGFA transforming growth factor alpha IEA KEGG hsa:05214 NCBI chr 2:70,447,284...70,553,826
Ensembl chr 2:70,447,284...70,554,193 		JBrowse link
G TP53 tumor protein p53 IEA KEGG hsa:05214 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 5956
    disease pathway 2076
      cancer pathway 389
        nervous system and nerve tissue cancer pathway 65
          glioma pathway 65
paths to the root