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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of actin filament polymerization
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Accession:GO:0030833 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the assembly of actin filaments by the addition of actin monomers to a filament.
Synonyms:exact_synonym: regulation of actin polymerization


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regulation of actin filament polymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABITRAM actin binding transcription modulator involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:64,094,653...64,100,078
Ensembl chr11:64,094,721...64,109,421 		JBrowse link
G ARHGAP18 Rho GTPase activating protein 18 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:68,143,702...68,262,440
Ensembl chr 1:68,143,702...68,275,022 		JBrowse link
G ARHGAP28 Rho GTPase activating protein 28 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 7:73,023,681...73,260,093
Ensembl chr 7:73,055,118...73,257,375 		JBrowse link
G ARPC3 actin related protein 2/3 complex subunit 3 involved_in IEA InterPro GO_REF:0000002 NCBI chr26:8,267,123...8,277,779
Ensembl chr26:8,267,196...8,277,688 		JBrowse link
G ARPC5 actin related protein 2/3 complex subunit 5 involved_in IEA InterPro GO_REF:0000002 NCBI chr 7:16,976,392...16,986,015
Ensembl chr 7:16,977,555...16,985,943 		JBrowse link
G ARPC5L actin related protein 2/3 complex subunit 5 like involved_in IEA InterPro GO_REF:0000002 NCBI chr 9:58,142,001...58,149,285
Ensembl chr 9:58,142,389...58,149,236 		JBrowse link
G BAIAP2L1 BAR/IMD domain containing adaptor protein 2 like 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr 6:10,968,100...11,055,040
Ensembl chr 6:10,968,060...11,053,494 		JBrowse link
G CORO1A coronin 1A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18836449) Ensembl
MGI		 PMID:18836449 GO_REF:0000107 NCBI chr 6:18,161,850...18,167,915
Ensembl chr 6:18,160,601...18,167,818 		JBrowse link
G COTL1 coactosin like F-actin binding protein 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 5:67,872,065...67,909,536
Ensembl chr 5:67,872,314...67,908,637 		JBrowse link
G CTTN cortactin involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr18:47,932,367...47,960,732
Ensembl chr18:47,916,632...47,960,674 		JBrowse link
G CYFIP1 cytoplasmic FMR1 interacting protein 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr 3:32,096,471...32,170,107
Ensembl chr 3:32,097,037...32,187,781 		JBrowse link
G CYFIP2 cytoplasmic FMR1 interacting protein 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr 4:52,769,638...52,875,080
Ensembl chr 4:52,743,048...52,880,589 		JBrowse link
G CYRIA CYFIP related Rac1 interactor A involved_in IEA InterPro GO_REF:0000002 NCBI chr17:12,208,319...12,311,775
Ensembl chr17:12,211,494...12,270,152 		JBrowse link
G CYRIB CYFIP related Rac1 interactor B involved_in IEA InterPro GO_REF:0000002 NCBI chr13:26,942,036...27,056,547
Ensembl chr13:26,942,229...27,003,644 		JBrowse link
G DAAM2 dishevelled associated activator of morphogenesis 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:8,686,653...8,801,903
Ensembl chr12:8,748,655...8,799,059 		JBrowse link
G DBN1 drebrin 1 involved_in ISO
IEA		 RGD
TreeGrafter		 PMID:19222710 GO_REF:0000118 RGD:10395284 NCBI chr 4:35,899,969...35,913,015
Ensembl chr 4:35,889,392...35,912,507 		JBrowse link
G DBNL drebrin like involved_in IEA TreeGrafter GO_REF:0000118
G ELN elastin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14614988) Ensembl
MGI		 PMID:14614988 GO_REF:0000107 NCBI chr 6:6,299,524...6,331,425
Ensembl chr 6:6,300,727...6,331,325 		JBrowse link
G ESAM endothelial cell adhesion molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:9,658,920...9,667,134
Ensembl chr 5:9,658,937...9,667,141 		JBrowse link
G FCHSD1 FCH and double SH3 domains 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 2:36,601,969...36,612,262
Ensembl chr 2:36,602,460...36,612,199 		JBrowse link
G FCHSD2 FCH and double SH3 domains 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr21:25,082,864...25,399,754
Ensembl chr21:25,072,161...25,397,717 		JBrowse link
G FER FER tyrosine kinase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 3:2,863,804...3,295,999
Ensembl chr 3:2,867,726...3,295,999 		JBrowse link
G GBA2 glucosylceramidase beta 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:52,264,959...52,277,298
Ensembl chr11:52,265,070...52,277,213 		JBrowse link
G HAX1 HCLS1 associated protein X-1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 7:42,969,711...42,972,783
Ensembl chr 7:42,969,713...42,972,710 		JBrowse link
G HCLS1 hematopoietic cell-specific Lyn substrate 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr33:24,901,023...24,925,710
Ensembl chr33:24,901,287...24,922,923 		JBrowse link
G LATS1 large tumor suppressor kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:40,430,096...40,475,193
Ensembl chr 1:40,260,064...40,457,609 		JBrowse link
G LOC106558389 profilin-1-like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr  X:49,614,163...49,614,624 JBrowse link
G PAK3 p21 (RAC1) activated kinase 3 involved_in ISO (PMID:21177870) UniProt PMID:21177870 NCBI chr  X:84,074,146...84,335,699
Ensembl chr  X:84,074,001...84,329,951 		JBrowse link
G PAK3 p21 (RAC1) activated kinase 3 involved_in IEA Ensembl GO_REF:0000107
G PFN1 profilin 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 5:31,670,483...31,671,891
Ensembl chr 5:31,670,194...31,671,895 		JBrowse link
G PFN2 profilin 2 involved_in ISO
IEA		 RGD
TreeGrafter		 PMID:11027290 GO_REF:0000118 RGD:727303 NCBI chr23:44,686,126...44,691,801
Ensembl chr23:44,686,937...44,691,800 		JBrowse link
G PFN3 profilin 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 4:35,959,558...35,960,296 JBrowse link
G PIK3R2 phosphoinositide-3-kinase regulatory subunit 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25217619) Ensembl
MGI		 PMID:25217619 GO_REF:0000107 NCBI chr20:44,826,037...44,838,449
Ensembl chr20:44,826,339...44,836,558 		JBrowse link
G PLEKHG2 pleckstrin homology and RhoGEF domain containing G2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:113,800,620...113,811,478
Ensembl chr 1:113,800,305...113,810,683 		JBrowse link
G PPP1R9A protein phosphatase 1 regulatory subunit 9A ISO RGD PMID:15473970 RGD:10043779 NCBI chr14:20,251,791...20,563,315
Ensembl chr14:20,251,738...20,557,208 		JBrowse link
G PREX1 phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 ISO RGD PMID:18697831 RGD:2314615 NCBI chr24:35,403,078...35,503,428
Ensembl chr24:35,404,564...35,582,041 		JBrowse link
G RASA1 RAS p21 protein activator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:21,068,182...21,177,288
Ensembl chr 3:21,054,930...21,176,757 		JBrowse link
G WASHC1 WASH complex subunit 1 acts_upstream_of_or_within ISO (PMID:26965651) MGI PMID:26965651 NCBI chr27:42,102,694...42,118,850
Ensembl chr27:42,099,886...42,116,339 		JBrowse link
actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AVIL advillin involved_in IEA UniProt GO_REF:0000043 NCBI chr10:1,855,598...1,875,156
Ensembl chr10:1,856,162...1,872,303 		JBrowse link
G CAPZA1 capping actin protein of muscle Z-line subunit alpha 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr17:62,900,062...62,948,164
Ensembl chr17:62,901,422...62,948,084 		JBrowse link
G CAPZA2 capping actin protein of muscle Z-line subunit alpha 2 involved_in IEA UniProt GO_REF:0000043 NCBI chr14:55,763,586...55,824,629
Ensembl chr14:55,763,249...55,824,629 		JBrowse link
G CAPZA3 capping actin protein of muscle Z-line subunit alpha 3 involved_in IEA UniProt GO_REF:0000043 NCBI chr27:28,362,103...28,363,171
Ensembl chr27:28,362,120...28,363,019 		JBrowse link
G CAPZB capping actin protein of muscle Z-line subunit beta involved_in IEA UniProt GO_REF:0000043 NCBI chr 2:79,182,668...79,311,529
Ensembl chr 2:79,181,851...79,311,518 		JBrowse link
G GSN gelsolin involved_in IEA Ensembl
UniProt		 GO_REF:0000043 GO_REF:0000107 NCBI chr11:74,248,227...74,268,129
Ensembl chr11:74,233,457...74,268,129 		JBrowse link
G LOC612266 F-actin-capping protein subunit alpha-1-like involved_in IEA UniProt GO_REF:0000043 NCBI chr11:60,158,542...60,160,368 JBrowse link
G MYH9 myosin heavy chain 9 NOT|involved_in ISO (MGI:5619440|PMID:23325791) UniProt PMID:23325791 MGI:5619440 NCBI chr10:28,063,626...28,122,953
Ensembl chr10:28,063,624...28,122,953 		JBrowse link
G RDX radixin involved_in IEA UniProt GO_REF:0000043 NCBI chr 5:22,555,913...22,642,822
Ensembl chr 5:22,571,286...22,642,811 		JBrowse link
G SCIN scinderin involved_in ISO (PMID:19666531) UniProt PMID:19666531 NCBI chr14:27,429,476...27,477,805
Ensembl chr14:27,412,351...27,477,283 		JBrowse link
G SPTA1 spectrin alpha, erythrocytic 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr38:23,052,046...23,118,933
Ensembl chr38:23,051,563...23,118,966 		JBrowse link
G SPTAN1 spectrin alpha, non-erythrocytic 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 9:54,953,751...55,015,475
Ensembl chr 9:54,953,747...55,015,376 		JBrowse link
G SPTB spectrin beta, erythrocytic involved_in IEA UniProt GO_REF:0000043 GO_REF:0000104 NCBI chr 8:39,156,388...39,300,908
Ensembl chr 8:39,158,795...39,221,193 		JBrowse link
G SPTBN1 spectrin beta, non-erythrocytic 1 involved_in IEA UniProt GO_REF:0000043 GO_REF:0000104 NCBI chr10:55,429,989...55,571,917
Ensembl chr10:55,429,940...55,571,916 		JBrowse link
G SPTBN2 spectrin beta, non-erythrocytic 2 involved_in IEA UniProt GO_REF:0000043 GO_REF:0000104 NCBI chr18:50,631,053...50,670,428
Ensembl chr18:50,631,909...50,669,916 		JBrowse link
G SPTBN4 spectrin beta, non-erythrocytic 4 involved_in IEA UniProt GO_REF:0000043 NCBI chr 1:113,167,251...113,243,071
Ensembl chr 1:113,168,484...113,240,934 		JBrowse link
G SPTBN4 involved_in IEA UniProt GO_REF:0000043
G TPM1 tropomyosin 1 ISO RGD PMID:15779917 RGD:1600523 NCBI chr30:27,636,407...27,664,907
Ensembl chr30:27,636,283...27,664,442 		JBrowse link
G VIL1 villin 1 involved_in IEA UniProt
Ensembl		 GO_REF:0000043 GO_REF:0000107 NCBI chr37:25,065,887...25,090,238
Ensembl chr37:25,065,180...25,090,705 		JBrowse link
G VILL villin like involved_in IEA UniProt GO_REF:0000043 NCBI chr23:7,767,028...7,782,167
Ensembl chr23:7,770,290...7,782,174 		JBrowse link
barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADD1 adducin 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 3:61,356,643...61,443,851
Ensembl chr 3:61,358,162...61,474,830 		JBrowse link
G ADD2 adducin 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr10:69,056,367...69,098,775
Ensembl chr10:69,057,267...69,098,521 		JBrowse link
G ADD3 adducin 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr28:21,402,068...21,527,006
Ensembl chr28:21,403,680...21,525,063 		JBrowse link
G AVIL advillin involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr10:1,855,598...1,875,156
Ensembl chr10:1,856,162...1,872,303 		JBrowse link
G CAPG capping actin protein, gelsolin like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:39,619,429...39,640,944
Ensembl chr17:39,619,248...39,640,942 		JBrowse link
G CAPZA1 capping actin protein of muscle Z-line subunit alpha 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17656356) InterPro
MGI
TreeGrafter
UniProt		 PMID:17656356 GO_REF:0000002 GO_REF:0000104 GO_REF:0000118 NCBI chr17:62,900,062...62,948,164
Ensembl chr17:62,901,422...62,948,084 		JBrowse link
G CAPZA2 capping actin protein of muscle Z-line subunit alpha 2 involved_in IEA
IBA		 InterPro
TreeGrafter
GO_Central
UniProt		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 GO_REF:0000118 NCBI chr14:55,763,586...55,824,629
Ensembl chr14:55,763,249...55,824,629 		JBrowse link
G CAPZA3 capping actin protein of muscle Z-line subunit alpha 3 involved_in IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000104 GO_REF:0000118 NCBI chr27:28,362,103...28,363,171
Ensembl chr27:28,362,120...28,363,019 		JBrowse link
G CAPZB capping actin protein of muscle Z-line subunit beta involved_in IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000104 GO_REF:0000118 NCBI chr 2:79,182,668...79,311,529
Ensembl chr 2:79,181,851...79,311,518 		JBrowse link
G DBNL drebrin like NOT|acts_upstream_of_or_within ISO (PMID:10637315) MGI PMID:10637315
G EPS8 EGFR pathway substrate 8, signaling adaptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:30,893,884...31,070,401
Ensembl chr27:30,893,713...31,069,770 		JBrowse link
G FLII FLII actin remodeling protein involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 5:41,303,015...41,314,849
Ensembl chr 5:41,302,767...41,314,862 		JBrowse link
G GSN gelsolin involved_in IEA UniProt
TreeGrafter		 GO_REF:0000104 GO_REF:0000118 NCBI chr11:74,248,227...74,268,129
Ensembl chr11:74,233,457...74,268,129 		JBrowse link
G LOC612266 F-actin-capping protein subunit alpha-1-like involved_in IEA InterPro
TreeGrafter
UniProt		 GO_REF:0000002 GO_REF:0000104 GO_REF:0000118 NCBI chr11:60,158,542...60,160,368 JBrowse link
G RDX radixin ISO RGD PMID:2500445 RGD:8693627 NCBI chr 5:22,555,913...22,642,822
Ensembl chr 5:22,571,286...22,642,811 		JBrowse link
G SCIN scinderin involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr14:27,429,476...27,477,805
Ensembl chr14:27,412,351...27,477,283 		JBrowse link
G SVIL supervillin involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 2:16,004,160...16,234,434
Ensembl chr 2:16,004,951...16,174,218 		JBrowse link
G TLR9 toll like receptor 9 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr20:37,529,322...37,547,117
Ensembl chr20:37,542,340...37,547,114
Ensembl chr20:37,542,340...37,547,114 		JBrowse link
G TWF1 twinfilin actin binding protein 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr27:10,281,249...10,295,550
Ensembl chr27:10,246,746...10,293,543 		JBrowse link
G TWF2 twinfilin actin binding protein 2 involved_in ISO (MGI:3840765|PMID:18837697) BHF-UCL PMID:18837697 MGI:3840765 NCBI chr20:37,529,322...37,539,955
Ensembl chr20:37,529,401...37,539,957 		JBrowse link
G VIL1 villin 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr37:25,065,887...25,090,238
Ensembl chr37:25,065,180...25,090,705 		JBrowse link
G VILL villin like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr23:7,767,028...7,782,167
Ensembl chr23:7,770,290...7,782,174 		JBrowse link
negative regulation of actin filament polymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADD1 adducin 1 ISO RGD PMID:8675693 RGD:7174724 NCBI chr 3:61,356,643...61,443,851
Ensembl chr 3:61,358,162...61,474,830 		JBrowse link
G ARFGEF1 ADP ribosylation factor guanine nucleotide exchange factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr29:16,712,872...16,852,478
Ensembl chr29:16,708,820...16,852,844 		JBrowse link
G ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23716571) Ensembl
MGI		 PMID:23716571 GO_REF:0000107 NCBI chr30:36,058,932...36,109,206
Ensembl chr30:35,927,233...36,108,381 		JBrowse link
G CAPN1 calpain 1 ISO RGD PMID:25653381 RGD:13792590 NCBI chr18:51,983,266...52,010,831
Ensembl chr18:51,983,824...52,010,757 		JBrowse link
G CYRIB CYFIP related Rac1 interactor B involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:26,942,036...27,056,547
Ensembl chr13:26,942,229...27,003,644 		JBrowse link
G FHOD3 formin homology 2 domain containing 3 acts_upstream_of_or_within ISO (PMID:19706596) MGI PMID:19706596 NCBI chr 7:53,477,273...53,933,532
Ensembl chr 7:53,478,930...53,934,331 		JBrowse link
G HIP1R huntingtin interacting protein 1 related involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:6,623,583...6,639,107
Ensembl chr26:6,624,791...6,637,659 		JBrowse link
G KANK1 KN motif and ankyrin repeat domains 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:17996375) MGI
TreeGrafter
InterPro
Ensembl		 PMID:17996375 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:89,446,340...89,618,716
Ensembl chr 1:89,480,399...89,618,143 		JBrowse link
G KANK2 KN motif and ankyrin repeat domains 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr20:50,067,749...50,093,377
Ensembl chr20:50,067,760...50,091,320 		JBrowse link
G KANK3 KN motif and ankyrin repeat domains 3 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr20:52,903,376...52,916,250
Ensembl chr20:52,903,372...53,102,139 		JBrowse link
G KANK4 KN motif and ankyrin repeat domains 4 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr 5:47,771,672...47,839,768
Ensembl chr 5:47,771,547...47,837,971 		JBrowse link
G MKKS MKKS centrosomal shuttling protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23716571) Ensembl
MGI		 PMID:23716571 GO_REF:0000107 NCBI chr24:11,887,504...11,914,055
Ensembl chr24:11,898,236...11,913,740 		JBrowse link
G MYADM myeloid associated differentiation marker involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:103,315,606...103,322,329 JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 ISO RGD PMID:17662049 RGD:7240703 NCBI chr 9:12,166,124...12,219,553
Ensembl chr 9:12,166,775...12,219,778 		JBrowse link
G PFN1 profilin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:31,670,483...31,671,891
Ensembl chr 5:31,670,194...31,671,895 		JBrowse link
G PFN2 profilin 2 involved_in ISO (PMID:7758455) UniProt PMID:7758455 NCBI chr23:44,686,126...44,691,801
Ensembl chr23:44,686,937...44,691,800 		JBrowse link
G PRKCD protein kinase C delta involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr20:36,723,491...36,751,982
Ensembl chr20:36,723,809...36,752,191 		JBrowse link
G SLIT2 slit guidance ligand 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:88,964,707...89,311,817
Ensembl chr 3:88,966,232...89,312,955 		JBrowse link
G SSH1 slingshot protein phosphatase 1 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr26:18,074,229...18,136,001
Ensembl chr26:18,074,075...18,131,185 		JBrowse link
G SSH2 slingshot protein phosphatase 2 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr 9:43,726,726...43,907,199
Ensembl chr 9:43,731,635...43,907,220 		JBrowse link
G SSH3 slingshot protein phosphatase 3 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr18:50,126,646...50,134,799
Ensembl chr18:50,126,663...50,134,729 		JBrowse link
G TLR2 toll like receptor 2 involved_in ISO (MGI:5307186|PMID:22198949) ARUK-UCL PMID:22198949 MGI:5307186 NCBI chr15:51,454,557...51,465,429
Ensembl chr15:51,454,695...51,465,241 		JBrowse link
G TLR9 toll like receptor 9 involved_in IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr20:37,529,322...37,547,117
Ensembl chr20:37,542,340...37,547,114
Ensembl chr20:37,542,340...37,547,114 		JBrowse link
G TWF1 twinfilin actin binding protein 1 involved_in IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr27:10,281,249...10,295,550
Ensembl chr27:10,246,746...10,293,543 		JBrowse link
G TWF2 twinfilin actin binding protein 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr20:37,529,322...37,539,955
Ensembl chr20:37,529,401...37,539,957 		JBrowse link
negative regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CARMIL1 capping protein regulator and myosin 1 linker 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr35:23,268,438...23,581,794
Ensembl chr35:23,268,723...23,581,403 		JBrowse link
G CARMIL2 capping protein regulator and myosin 1 linker 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:81,792,683...81,804,274
Ensembl chr 5:81,792,155...81,804,152 		JBrowse link
G CRACD capping protein inhibiting regulator of actin dynamics involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118
G PAICS phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr13:48,296,232...48,682,650 JBrowse link
G WASHC2C WASH complex subunit 2C involved_in ISO (PMID:20498093) UniProt PMID:20498093 NCBI chr28:1,867,680...1,923,273 JBrowse link
pointed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASB15 ankyrin repeat and SOCS box containing 15 involved_in IEA InterPro GO_REF:0000002 NCBI chr14:11,931,538...11,995,790
Ensembl chr14:11,919,034...11,989,939 		JBrowse link
G LMOD1 leiomodin 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr 7:1,025,022...1,059,254 JBrowse link
G LMOD2 leiomodin 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr14:11,916,842...11,924,616
Ensembl chr14:11,917,878...11,924,438 		JBrowse link
G LMOD3 leiomodin 3 involved_in IEA InterPro GO_REF:0000002 NCBI chr20:22,612,916...22,629,207
Ensembl chr20:22,612,946...22,629,214 		JBrowse link
G TMOD1 tropomodulin 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr11:54,853,205...54,914,236
Ensembl chr11:54,853,204...54,912,773 		JBrowse link
G TMOD2 tropomodulin 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr30:17,425,216...17,501,484
Ensembl chr30:17,455,987...17,592,580 		JBrowse link
G TMOD3 tropomodulin 3 involved_in IEA InterPro GO_REF:0000002 NCBI chr30:17,509,533...17,594,355
Ensembl chr30:17,455,987...17,592,580 		JBrowse link
G TMOD4 tropomodulin 4 involved_in IEA InterPro GO_REF:0000002 NCBI chr17:60,234,061...60,238,950
Ensembl chr17:60,234,096...60,238,864 		JBrowse link
positive regulation of actin filament polymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTR3 actin related protein 3 ISO RGD PMID:18256280 RGD:2306202 NCBI chr19:35,097,968...35,133,330
Ensembl chr19:35,098,639...35,169,724 		JBrowse link
G ALOX15 arachidonate 15-lipoxygenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:31,883,544...31,891,357
Ensembl chr 5:31,882,501...32,038,119 		JBrowse link
G ARF6 ADP ribosylation factor 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:26,445,407...26,449,430
Ensembl chr 8:26,445,647...26,525,530 		JBrowse link
G ARPC2 actin related protein 2/3 complex subunit 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18836449) Ensembl
MGI		 PMID:18836449 GO_REF:0000107 NCBI chr37:24,914,389...24,935,998
Ensembl chr37:24,914,642...24,935,824 		JBrowse link
G BAG4 BAG cochaperone 4 involved_in ISO (MGI:5292318|PMID:21712384) UniProt PMID:21712384 MGI:5292318 NCBI chr16:27,270,947...27,304,178
Ensembl chr16:27,273,848...27,303,786 		JBrowse link
G BAIAP2 BAR/IMD domain containing adaptor protein 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 9:923,519...992,254
Ensembl chr 9:923,493...981,923 		JBrowse link
G BAIAP2L1 BAR/IMD domain containing adaptor protein 2 like 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:10,968,100...11,055,040
Ensembl chr 6:10,968,060...11,053,494 		JBrowse link
G BAIAP2L2 BAR/IMD domain containing adaptor protein 2 like 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr10:26,560,328...26,587,654
Ensembl chr10:26,560,494...26,574,052 		JBrowse link
G BIN1 bridging integrator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:23,503,934...23,534,407
Ensembl chr19:23,375,363...23,534,303 		JBrowse link
G C30H15orf62 chromosome 30 C15orf62 homolog involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr30:7,904,715...7,909,042
Ensembl chr30:7,907,101...7,907,628 		JBrowse link
G CARMIL1 capping protein regulator and myosin 1 linker 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr35:23,268,438...23,581,794
Ensembl chr35:23,268,723...23,581,403 		JBrowse link
G CCL21 C-C motif chemokine ligand 21 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:51,375,107...51,375,790 JBrowse link
G CCL24 C-C motif chemokine ligand 24 involved_in ISO (PMID:19525930) BHF-UCL PMID:19525930 NCBI chr 6:7,166,165...7,179,606
Ensembl chr 6:7,166,479...7,180,051 		JBrowse link
G CCL26 C-C motif chemokine ligand 26 involved_in ISO (PMID:19525930) BHF-UCL PMID:19525930 NCBI chr 6:7,151,352...7,154,509
Ensembl chr 6:7,151,212...7,154,726 		JBrowse link
G CDC42EP1 CDC42 effector protein 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr10:27,016,415...27,020,700
Ensembl chr10:27,017,077...27,019,582 		JBrowse link
G CDC42EP2 CDC42 effector protein 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr18:51,854,975...51,863,594
Ensembl chr18:51,857,367...51,858,011 		JBrowse link
G CDC42EP3 CDC42 effector protein 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:29,949,452...29,973,008
Ensembl chr17:29,950,210...29,973,008 		JBrowse link
G CDC42EP4 CDC42 effector protein 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 9:6,888,183...6,909,986
Ensembl chr 9:6,907,205...6,964,626 		JBrowse link
G CDC42EP5 CDC42 effector protein 5 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:102,838,163...102,842,586
Ensembl chr 1:102,842,052...102,842,513 		JBrowse link
G CRACD capping protein inhibiting regulator of actin dynamics involved_in IEA Ensembl GO_REF:0000107
G CSF3 colony stimulating factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:22,529,643...22,532,326
Ensembl chr 9:22,530,698...22,533,108 		JBrowse link
G CTTN cortactin involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:47,932,367...47,960,732
Ensembl chr18:47,916,632...47,960,674 		JBrowse link
G DLG1 discs large MAGUK scaffold protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15699074) Ensembl
MGI		 PMID:15699074 GO_REF:0000107 NCBI chr33:30,016,323...30,253,180
Ensembl chr33:30,016,600...30,253,547 		JBrowse link
G EVL Enah/Vasp-like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 8:68,352,717...68,461,684
Ensembl chr 8:68,352,853...68,484,269 		JBrowse link
G FCHSD1 FCH and double SH3 domains 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:36,601,969...36,612,262
Ensembl chr 2:36,602,460...36,612,199 		JBrowse link
G FCHSD2 FCH and double SH3 domains 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:25,082,864...25,399,754
Ensembl chr21:25,072,161...25,397,717 		JBrowse link
G FER FER tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:2,863,804...3,295,999
Ensembl chr 3:2,867,726...3,295,999 		JBrowse link
G FMN1 formin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14647292) Ensembl
MGI		 PMID:14647292 GO_REF:0000107 NCBI chr30:1,782,726...2,215,449
Ensembl chr30:1,815,512...2,184,909 		JBrowse link
G GRB2 growth factor receptor bound protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17923684) Ensembl
MGI		 PMID:17923684 GO_REF:0000107 NCBI chr 9:5,108,128...5,182,091
Ensembl chr 9:5,117,164...5,180,296 		JBrowse link
G GRID2IP Grid2 interacting protein involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:11,834,841...11,860,326
Ensembl chr 6:11,835,961...11,870,109 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO RGD PMID:17662049 RGD:7240703 NCBI chr20:50,818,715...50,827,914
Ensembl chr20:50,818,715...50,827,914 		JBrowse link
G KIRREL1 kirre like nephrin family adhesion molecule 1 acts_upstream_of_or_within ISO (PMID:17923684) MGI PMID:17923684 NCBI chr38:23,530,930...23,593,957
Ensembl chr38:23,530,885...23,594,236 		JBrowse link
G LMOD1 leiomodin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:1,025,022...1,059,254 JBrowse link
G LMOD2 leiomodin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:11,916,842...11,924,616
Ensembl chr14:11,917,878...11,924,438 		JBrowse link
G LOC119876109 vasodilator-stimulated phosphoprotein-like involved_in IEA TreeGrafter GO_REF:0000118
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 acts_upstream_of_or_within ISO (PMID:12941696), (PMID:25224220) MGI PMID:12941696 PMID:25224220 NCBI chr 2:43,918,210...43,996,817
Ensembl chr 2:43,917,604...43,995,209 		JBrowse link
G MLST8 MTOR associated protein, LST8 homolog involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15467718) Ensembl
MGI		 PMID:15467718 GO_REF:0000107 NCBI chr 6:38,759,713...38,765,556
Ensembl chr 6:38,762,103...38,765,488 		JBrowse link
G MTOR mechanistic target of rapamycin kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15467718) Ensembl
MGI		 PMID:15467718 GO_REF:0000107 NCBI chr 2:84,818,893...84,939,283
Ensembl chr 2:84,787,708...84,939,114 		JBrowse link
G MYO1C myosin IC ISO RGD PMID:22918957 RGD:11073622 NCBI chr 9:45,635,295...45,658,226
Ensembl chr 9:45,636,208...45,658,035 		JBrowse link
G NCK1 NCK adaptor protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17923684) Ensembl
MGI
UniProt		 PMID:17923684 GO_REF:0000104 GO_REF:0000107 NCBI chr23:33,297,660...33,374,025
Ensembl chr23:33,297,756...33,372,534 		JBrowse link
G NCK2 NCK adaptor protein 2 involved_in IEA Ensembl
UniProt		 GO_REF:0000104 GO_REF:0000107 NCBI chr10:37,584,351...37,734,388
Ensembl chr10:37,585,565...37,732,994 		JBrowse link
G NCKAP1 NCK associated protein 1 involved_in ISO (MGI:5897521|PMID:27927633) BHF-UCL PMID:27927633 MGI:5897521 NCBI chr36:25,965,243...26,054,775
Ensembl chr36:25,965,938...26,054,760 		JBrowse link
G NCKAP1L NCK associated protein 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:805,274...858,901
Ensembl chr27:805,310...843,439 		JBrowse link
G NPHS1 NPHS1 adhesion molecule, nephrin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:116,794,891...116,814,418
Ensembl chr 1:116,794,433...116,813,546 		JBrowse link
G PFN1 profilin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:31,670,483...31,671,891
Ensembl chr 5:31,670,194...31,671,895 		JBrowse link
G PFN2 profilin 2 involved_in
acts_upstream_of_or_within		 ISO (PMID:23153535)
(PMID:17541406)		 UniProt
MGI		 PMID:17541406 PMID:23153535 NCBI chr23:44,686,126...44,691,801
Ensembl chr23:44,686,937...44,691,800 		JBrowse link
G PRKCE protein kinase C epsilon involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:47,976,929...48,464,614
Ensembl chr10:47,976,768...48,535,296 		JBrowse link
G PTK2B protein tyrosine kinase 2 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:30,137,546...30,264,221
Ensembl chr25:30,138,209...30,264,133 		JBrowse link
G PYCARD PYD and CARD domain containing involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:17,049,352...17,051,348
Ensembl chr 6:17,049,705...17,051,240 		JBrowse link
G RAC1 Rac family small GTPase 1 acts_upstream_of_or_within ISO (PMID:12853475) MGI PMID:12853475 NCBI chr 6:11,726,259...11,758,532
Ensembl chr 6:11,655,494...11,757,216 		JBrowse link
G RHOA ras homolog family member A ISO RGD PMID:17369454 RGD:1642965 NCBI chr20:39,824,552...39,888,089
Ensembl chr20:39,824,575...39,887,215 		JBrowse link
G RICTOR RPTOR independent companion of MTOR complex 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15467718) Ensembl
MGI		 PMID:15467718 GO_REF:0000107 NCBI chr 4:69,903,393...70,013,168
Ensembl chr 4:69,936,379...70,010,566 		JBrowse link
G SNX9 sorting nexin 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:47,346,214...47,457,417
Ensembl chr 1:47,343,668...47,455,937 		JBrowse link
G TENM1 teneurin transmembrane protein 1 involved_in ISO (MGI:5465054|PMID:22698694) UniProt PMID:22698694 MGI:5465054 NCBI chr  X:95,766,173...96,565,995
Ensembl chr  X:95,769,881...96,550,190 		JBrowse link
G VASP vasodilator stimulated phosphoprotein involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:110,050,154...110,063,125
Ensembl chr 1:110,050,154...110,062,827 		JBrowse link
positive regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARPC2 actin related protein 2/3 complex subunit 2 ISO RGD PMID:15252126 RGD:2306210 NCBI chr37:24,914,389...24,935,998
Ensembl chr37:24,914,642...24,935,824 		JBrowse link
G CFL1 cofilin 1 ISO RGD PMID:23704350 RGD:11570555 NCBI chr18:51,404,649...51,408,240
Ensembl chr18:51,401,659...51,408,212 		JBrowse link
regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKRD44 ankyrin repeat domain 44 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr37:6,500,741...6,756,505
Ensembl chr37:6,541,554...6,753,028 		JBrowse link
G ANKRD52 ankyrin repeat domain 52 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr10:562,510...574,641
Ensembl chr10:546,964...574,744 		JBrowse link
G ASB10 ankyrin repeat and SOCS box containing 10 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr16:15,220,042...15,230,702
Ensembl chr16:15,220,507...15,230,134 		JBrowse link
G ASB12 ankyrin repeat and SOCS box containing 12 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr  X:49,459,926...49,465,761
Ensembl chr  X:49,462,751...49,469,686 		JBrowse link
G ASB15 ankyrin repeat and SOCS box containing 15 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr14:11,931,538...11,995,790
Ensembl chr14:11,919,034...11,989,939 		JBrowse link
G ASB7 ankyrin repeat and SOCS box containing 7 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 3:40,365,515...40,415,345
Ensembl chr 3:40,320,391...40,414,671 		JBrowse link
G MTPN myotrophin involved_in ISS
IBA
IEA		 UniProt
GO_Central
TreeGrafter		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000118 NCBI chr16:12,316,487...12,369,148
Ensembl chr16:12,316,336...12,369,387 		JBrowse link
G TNNI3K TNNI3 interacting kinase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:71,825,853...72,107,832
Ensembl chr 6:71,815,734...72,119,476 		JBrowse link
sequestering of actin monomers term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GSN gelsolin involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:74,248,227...74,268,129
Ensembl chr11:74,233,457...74,268,129 		JBrowse link
G LOC100683370 thymosin beta-4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:21,127,694...21,128,346 JBrowse link
G LOC102152706 thymosin beta-4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 9:44,833,651...44,833,834 JBrowse link
G LOC119871020 thymosin beta-15A-like involved_in IEA TreeGrafter GO_REF:0000118
G LOC119881789 profilin-4 involved_in IEA TreeGrafter GO_REF:0000118
G PFN4 profilin family member 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:18,571,201...18,579,593
Ensembl chr17:18,573,445...18,578,818 		JBrowse link
G SCIN scinderin involved_in ISO (PMID:19666531) UniProt PMID:19666531 NCBI chr14:27,429,476...27,477,805
Ensembl chr14:27,412,351...27,477,283 		JBrowse link
G TLR9 toll like receptor 9 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr20:37,529,322...37,547,117
Ensembl chr20:37,542,340...37,547,114
Ensembl chr20:37,542,340...37,547,114 		JBrowse link
G TMSB10 thymosin beta 10 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:40,048,823...40,049,508
Ensembl chr17:40,048,828...40,049,470 		JBrowse link
G TMSB4X thymosin beta 4 X-linked involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr  X:9,434,351...9,436,436 JBrowse link
G TWF1 twinfilin actin binding protein 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr27:10,281,249...10,295,550
Ensembl chr27:10,246,746...10,293,543 		JBrowse link
G TWF2 twinfilin actin binding protein 2 involved_in ISO (MGI:3840765|PMID:18837697) BHF-UCL PMID:18837697 MGI:3840765 NCBI chr20:37,529,322...37,539,955
Ensembl chr20:37,529,401...37,539,957 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17924
    cellular process 16926
      regulation of cellular process 11579
        regulation of cellular component organization 2760
          regulation of protein-containing complex assembly 470
            regulation of protein polymerization 222
              regulation of actin filament polymerization 158
                negative regulation of actin filament polymerization + 81
                positive regulation of actin filament polymerization + 58
                regulation of barbed-end actin filament capping + 15
Path 2
Term Annotations click to browse term
  biological_process 17924
    cellular process 16926
      cellular component organization or biogenesis 6958
        cellular component organization 6720
          organelle organization 3764
            cytoskeleton organization 1592
              actin cytoskeleton organization 769
                actin filament organization 494
                  actin polymerization or depolymerization 221
                    regulation of actin polymerization or depolymerization 178
                      regulation of actin filament polymerization 158
                        negative regulation of actin filament polymerization + 81
                        positive regulation of actin filament polymerization + 58
                        regulation of barbed-end actin filament capping + 15
paths to the root