PRKCD (protein kinase C delta) - Rat Genome Database

Name: PRKCD
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: PRKCD (protein kinase C delta) Canis lupus familiaris

Analyze

Symbol:

PRKCD

Name:

protein kinase C delta

RGD ID:

12313139

Description:

ENCODES a protein that exhibits diacylglycerol-dependent serine/threonine kinase activity (ortholog); diacylglycerol-dependent, calcium-independent serine/threonine kinase activity (ortholog); protein kinase binding (ortholog); INVOLVED IN apoptotic process (ortholog); B cell proliferation (ortholog); cellular response to angiotensin (ortholog); PARTICIPATES IN ceramide signaling pathway; eicosanoid signaling pathway; endothelin signaling pathway; ASSOCIATED WITH autoimmune lymphoproliferative syndrome type 3 (ortholog); brain ischemia (ortholog); Burns (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); endolysosome (ortholog)

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

nPKC-delta; protein kinase C delta type; tyrosine-protein kinase PRKCD

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PRKCD (protein kinase C delta)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Prkcd (protein kinase C, delta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Prkcd (protein kinase C, delta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Prkcd (protein kinase C delta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PRKCD (protein kinase C delta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Prkcd (protein kinase C delta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PRKCD (protein kinase C delta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PRKCD (protein kinase C delta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Prkcd (protein kinase C delta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	36,723,491 - 36,751,982 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	36,723,809 - 36,752,191 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	36,660,459 - 36,673,894 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	37,001,697 - 37,030,998 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	37,001,704 - 37,031,073 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	36,438,983 - 36,452,419 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	36,800,686 - 36,814,133 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	37,015,742 - 37,029,186 (-)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autoimmune lymphoproliferative syndrome type 3 (ISO)

brain ischemia (ISO)

Burns (ISO)

Cardiomegaly (ISO)

Chemical and Drug Induced Liver Injury (ISO)

Experimental Diabetes Mellitus (ISO)

Experimental Liver Cirrhosis (ISO)

Fever (ISO)

genetic disease (ISO)

hyperinsulinism (ISO)

hypertension (ISO)

Hypothermia (ISO)

Insulin Resistance (ISO)

Intestinal Neoplasms (ISO)

Left Ventricular Hypertrophy (ISO)

metabolic dysfunction-associated steatotic liver disease (ISO)

muscular disease (ISO)

Myocardial Ischemia (ISO)

Myocardial Reperfusion Injury (ISO)

obesity (ISO)

Parkinsonism (ISO)

portal hypertension (ISO)

restrictive cardiomyopathy (ISO)

Right Ventricular Hypertrophy (ISO)

steatotic liver disease (ISO)

Stroke (ISO)

toxic encephalopathy (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

apoptotic process (IEA,ISS)

B cell proliferation (IEA,ISO)

cell chemotaxis (IEA)

cellular response to angiotensin (IEA,ISS)

cellular response to glucose starvation (ISO)

cellular response to hydrogen peroxide (IEA)

cellular response to hydroperoxide (IEA)

cellular response to insulin stimulus (ISO)

cellular response to oxidative stress (ISO)

cellular response to UV (IEA,ISS)

cellular senescence (IEA)

collagen metabolic process (ISO)

D-aspartate import across plasma membrane (ISO)

defense response to bacterium (IEA,ISS)

DNA damage response (IEA)

immunoglobulin mediated immune response (IEA,ISO)

intracellular signal transduction (IBA,IEA,ISO)

negative regulation of actin filament polymerization (IEA,ISS)

negative regulation of filopodium assembly (IEA,ISS)

negative regulation of glial cell apoptotic process (IEA,ISS)

negative regulation of insulin receptor signaling pathway (IEA)

negative regulation of peptidyl-tyrosine phosphorylation (IEA)

negative regulation of platelet aggregation (IEA,ISS)

neutrophil activation (IEA)

positive regulation of apoptotic process (ISO)

positive regulation of apoptotic signaling pathway (IEA,ISO)

positive regulation of ceramide biosynthetic process (IEA)

positive regulation of glucose import (ISO)

positive regulation of glucosylceramide catabolic process (IEA)

positive regulation of MAP kinase activity (ISO)

positive regulation of MAPK cascade (ISO)

positive regulation of protein dephosphorylation (IEA)

positive regulation of protein import into nucleus (IEA)

positive regulation of sphingomyelin catabolic process (IEA)

positive regulation of superoxide anion generation (IEA,ISS)

post-translational protein modification (IEA)

protein autophosphorylation (ISO)

protein phosphorylation (ISO)

regulation of actin cytoskeleton organization (IEA)

regulation of ceramide biosynthetic process (IEA,ISS)

regulation of phosphorylation (ISO)

response to amino acid (ISO)

response to ethanol (ISO)

response to glucose (ISO)

response to hydrogen peroxide (ISO)

response to hypoxia (ISO)

response to mechanical stimulus (ISO)

response to organic cyclic compound (ISO)

response to organonitrogen compound (ISO)

response to oxidative stress (ISO)

response to xenobiotic stimulus (ISO)

termination of signal transduction (IEA)

Cellular Component

cell-cell junction (IEA)

cytoplasm (IEA,ISS)

cytosol (IEA,ISS)

endolysosome (IEA,ISS)

endomembrane system (IEA)

endoplasmic reticulum (IEA,ISS)

membrane (IEA)

mitochondrion (IEA,ISS)

nuclear matrix (IEA)

nucleus (IEA,ISS)

perinuclear region of cytoplasm (IEA)

plasma membrane (IEA,ISS)

postsynaptic cytosol (ISO)

Molecular Function

ATP binding (IEA)

diacylglycerol-dependent serine/threonine kinase activity (IEA,ISS)

diacylglycerol-dependent, calcium-independent serine/threonine kinase activity (ISO)

enzyme activator activity (IEA)

enzyme binding (IEA)

insulin receptor substrate binding (IEA)

kinase activity (IEA)

metal ion binding (IEA)

non-membrane spanning protein tyrosine kinase activity (IEA)

nucleotide binding (IEA)

protein binding (ISO)

protein kinase activity (IEA)

protein kinase binding (IEA,ISO)

protein serine kinase activity (IEA,ISS)

protein serine/threonine kinase activity (IBA,IEA,ISS)

protein tyrosine kinase activity (IEA)

TIR domain binding (ISO)

transferase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

ceramide signaling pathway (ISO)

eicosanoid signaling pathway (ISO)

endothelin signaling pathway (ISO)

Hedgehog signaling pathway (ISO)

insulin-like growth factor signaling pathway (ISO)

interleukin-6 signaling pathway (ISO)

p53 signaling pathway (ISO)

platelet-derived growth factor signaling pathway (ISO)

protein kinase C (PKC) signaling pathway (ISO)

syndecan signaling pathway (ISO)

the extracellular signal-regulated Raf/Mek/Erk signaling pathway (ISO)

type II interferon signaling pathway (ISO)

vascular endothelial growth factor signaling pathway (ISO)

References

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

PRKCD
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	36,723,491 - 36,751,982 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	36,723,809 - 36,752,191 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	36,660,459 - 36,673,894 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	37,001,697 - 37,030,998 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	37,001,704 - 37,031,073 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	36,438,983 - 36,452,419 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	36,800,686 - 36,814,133 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	37,015,742 - 37,029,186 (-)	NCBI		UU_Cfam_GSD_1.0

PRKCD
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	53,161,209 - 53,192,717 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	53,156,009 - 53,192,717 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	53,195,225 - 53,226,733 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	53,170,263 - 53,201,773 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	3	53,170,262 - 53,201,771	NCBI
Celera	3	53,162,239 - 53,193,756 (+)	NCBI		Celera
Cytogenetic Map	3	p21.1	NCBI
HuRef	3	53,210,511 - 53,276,026 (+)	NCBI		HuRef
CHM1_1	3	53,146,796 - 53,178,291 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	3	53,194,119 - 53,225,596 (+)	NCBI		T2T-CHM13v2.0

Prkcd
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	30,317,310 - 30,348,637 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	30,317,311 - 30,348,167 (-)	Ensembl		GRCm39 Ensembl
GRCm38	14	30,595,353 - 30,626,414 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	30,595,354 - 30,626,210 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	14	31,408,555 - 31,423,498 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	14	29,424,378 - 29,447,560 (-)	NCBI		MGSCv36	mm8
Celera	14	26,853,019 - 26,867,962 (-)	NCBI		Celera
Cytogenetic Map	14	B	NCBI
cM Map	14	18.82	NCBI

Prkcd
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	5,775,681 - 5,806,122 (-)	NCBI		GRCr8
mRatBN7.2	16	5,769,217 - 5,799,380 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	5,769,215 - 5,799,352 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	16	5,781,205 - 5,811,322 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	6,926,659 - 6,956,775 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	5,779,783 - 5,809,932 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	6,655,131 - 6,675,746 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	6,655,120 - 6,675,746 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	6,588,990 - 6,608,725 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	5,954,218 - 5,975,743 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	16	5,954,214 - 5,975,741 (-)	NCBI
Celera	16	9,398,816 - 9,419,806 (+)	NCBI		Celera
Cytogenetic Map	16	p16	NCBI

Prkcd
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955430	3,124,738 - 3,153,274 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955430	3,125,066 - 3,151,857 (+)	NCBI	ChiLan1.0	ChiLan1.0

PRKCD
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	53,157,598 - 53,189,084 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	53,162,376 - 53,193,855 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	53,104,137 - 53,135,588 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	54,330,328 - 54,357,910 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	54,330,328 - 54,357,910 (+)	Ensembl	panpan1.1		panPan2

Prkcd
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	170,754,028 - 170,788,044 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936473	3,892,366 - 3,923,515 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936473	3,892,625 - 3,923,467 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PRKCD
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	35,290,610 - 35,323,356 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	35,290,835 - 35,323,245 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	38,361,707 - 38,390,508 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PRKCD
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	22	14,561,401 - 14,592,877 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	22	14,565,282 - 14,592,873 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666041	152,302,998 - 152,334,406 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Prkcd
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624822	4,033,130 - 4,059,555 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624822	4,035,819 - 4,062,907 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in PRKCD
230 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	reproductive system	respiratory system	adipose tissue
High
Medium	4		15		6		6		8	8	10	2
Low	1	5	7	6		6		1	4			4
Below cutoff								5

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001008716	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005632338	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005632339	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022406253	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038426494	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038426495	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038426496	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038426497	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000020	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY825360	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000235	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000058	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000291	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000020	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCAFT00000013836 ⟹ ENSCAFP00000012799

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	20	36,723,809 - 36,752,191 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00000061719 ⟹ ENSCAFP00000046558

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	20	36,723,809 - 36,752,191 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00000081996 ⟹ ENSCAFP00000043544

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	20	36,726,571 - 36,752,191 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00845050861 ⟹ ENSCAFP00845039871

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	20	37,001,704 - 37,031,073 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00845050941 ⟹ ENSCAFP00845039935

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	20	37,001,704 - 37,031,073 (-)	Ensembl

RefSeq Acc Id:

NM_001008716 ⟹ NP_001008716

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	20	36,724,062 - 36,737,498 (-)	NCBI
Dog10K_Boxer_Tasha	20	36,660,459 - 36,673,894 (-)	NCBI
ROS_Cfam_1.0	20	37,002,268 - 37,015,695 (-)	NCBI
UMICH_Zoey_3.1	20	36,438,983 - 36,452,419 (-)	NCBI
UNSW_CanFamBas_1.0	20	36,800,686 - 36,814,133 (-)	NCBI
UU_Cfam_GSD_1.0	20	37,015,742 - 37,029,186 (-)	NCBI

Sequence:

show sequence

ATGGCGCCGTTCCTGCGCATCGCCTTCACCTCCTATGAGCTGGGCTCCCTGCAGGCCGCCGATG
AGGCCAGCCAGCCCTTCTGTGCCGTGAAGATGAAGGAGGCACTCAGCACAGAGCGCGGGAAGAC
GCTGGTGCAGAAGAAGCCCACCATGTACCCTGAGTGGAAGTCCACATTCGACGCCCACATCTAC
GAGGGCCGAGTCATCCAGATCGTGCTGATGCGGGCAGCTGAAGAGCCGATGTCCGAGGTGACGG
TGGGCGTGTCGGTGCTGGCCGAGCGCTGCAAGAAGAACAACNAAAAGGCCGAGTTCTGGCTGGA
CCTGCAACCCCAGGCCAAGGTGTTGATGTCTGTGCAGTATTTTCTGGAAGACATAGATTGCAGA
CAGTCTATGCATGGTGAAGACGAGGCCAAGTTACCAACAATGAACCGCCGTGGAGCCATCAAAC
AGGCCAAAATCCACTACATCAAGAACCACGAGTTTATTGCCACCTTCTTCGGACAGCCTACTTT
CTGTTCTGTGTGCAAAGACTTTGTTTGGGGTCTCAACAAGCAAGGCTACAAATGCAGGCAATGC
AACGCTGCCATCCACAAGAAATGCATCGACAAGATCATCGGCCGGTGCACGGGCACCGCAGCCA
ACAGCCGGGACACCATATTCCAGAAAGAACGTTTCAACATCGACATGCCGCACCGATTCAAGGT
TTACAACTACATGAGCCCCACCTTCTGTGACCACTGTGGCAGTCTGCTCTGGGGGCTGGTGAAG
CAGGGATTAAAATGTGAAGACTGTGGCATGAATGTACACCATAAGTGCCAGAAGAAAGTGGCCA
ACCTCTGTGGCATTAACCAGAAGCTCTTGGCTGAGGCATTGAACCAAGTGACCCAGAGATCCTC
CCGGAAGTCAGAAACAGAGTCTGTTGGAATCTACCAGAATTTTGAGAGAAAGCCAGGAGTCTCT
GGAGACATTGCCCCAGGTGAAGACAACGGGACGTACGGCAAGATCTGGGAGGGCAGCACCAGGT
GCAACATTGACAACTTCATCTTCCACAAGGTCCTGGGCAAAGGCAGCTTTGGGAAGGTGCTGCT
TGTAGAGCTGAAGGGCAAGAAGGAGTTCTTTGCTATCAAGGCTCTTAAGAAGGACGTGGTTCTG
ATCGACGATGACGTGGAGTGCACCATGGTGGAGAAGCGGGTGCTGGCGCTCGCCTGGGAGAATC
CCTTTCTCACCCACCTGTTCTGCACATTTCAGACCAAGGACCACCTGTTCTTCGTGATGGAGTT
CCTCAATGGTGGGGACCTCATGTACCACATCCAGGACAAAGGCCGCTTCGAGCTCTATCGGGCC
ACGTTTTATGCAGCTGAGATAGTCTGTGGATTGCAGTTTCTGCACAACAAAGGGATCATTTACA
GGGACCTCAAGCTGGACAATGTGATGCTGGACCAGGATGGCCACATCAAGATTGCTGACTTTGG
GATGTGCAAGGAGAACATATTTGGGGAGAAACAGGCTAGCACCTTCTGTGGCACCCCTGACTAT
ATTGCCCCCGAGATCCTGCAGGGCCTAAAGTACTCCTTCTCTGTGGACTGGTGGTCCTTTGGAG
TCCTTCTCTACGAGATGCTCATTGGTCAGTCCCCCTTCCACGGTGACGATGAGGACGAACTCTT
CGAGTCCATCCGTGTGGACACGCCACATTATCCCCGCTGGATCACCAAGGAGTCCAAGGACATC
CTGGAGAAGCTGCTTGAAAGAGATACAACCAAGAGGCTGGGAGTGACGGGCAACATCAAAATCC
ACCCGTTCTTCAAGACCATTAACTGGACCCTGCTGGAGAAACGGGCTGTGGAGCCGCCCTTCAA
GCCCAAAGTGAAGTCCCCTGGAGACTACAGTAACTTTGACCAGGAGTTCCTGAACGAGAAGGCA
CGCCTCTCCTACACCGATAAGAACCTCATCGACTCCATGGACCAAACAGCATTCGCTGGCTTCT
CCTTTGTGAACCCCAAATTTGAGAGATTCCTGGAAAAGTGA

hide sequence

RefSeq Acc Id:

XM_038426494 ⟹ XP_038282422

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	20	37,001,697 - 37,030,995 (-)	NCBI

RefSeq Acc Id:

XM_038426495 ⟹ XP_038282423

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	20	37,001,697 - 37,030,995 (-)	NCBI

RefSeq Acc Id:

XM_038426496 ⟹ XP_038282424

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	20	37,002,262 - 37,030,998 (-)	NCBI

RefSeq Acc Id:

XM_038426497 ⟹ XP_038282425

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	20	37,001,697 - 37,014,951 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001008716	(Get FASTA)	NCBI Sequence Viewer
	XP_038282422	(Get FASTA)	NCBI Sequence Viewer
	XP_038282423	(Get FASTA)	NCBI Sequence Viewer
	XP_038282424	(Get FASTA)	NCBI Sequence Viewer
	XP_038282425	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAV80465	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000012799.4
	ENSCAFP00000043544.2
	ENSCAFP00000046558.1
	ENSCAFP00000067871.1
	ENSCAFP00030042291.1
	ENSCAFP00030042294.1
	ENSCAFP00040030692.1
	ENSCAFP00040030801.1
	ENSCAFP00845039871
	ENSCAFP00845039871.1
	ENSCAFP00845039935.1
GenBank Protein	Q5PU49	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001008716 ⟸ NM_001008716

- UniProtKB:

Q5PU49 (UniProtKB/Swiss-Prot), A0A8C0PZJ7 (UniProtKB/TrEMBL), A0A8C0T441 (UniProtKB/TrEMBL), A0A8I3Q187 (UniProtKB/TrEMBL), A0A8P0NWP8 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAPFLRIAFTSYELGSLQAADEASQPFCAVKMKEALSTERGKTLVQKKPTMYPEWKSTFDAHIY
EGRVIQIVLMRAAEEPMSEVTVGVSVLAERCKKNNXKAEFWLDLQPQAKVLMSVQYFLEDIDCR
QSMHGEDEAKLPTMNRRGAIKQAKIHYIKNHEFIATFFGQPTFCSVCKDFVWGLNKQGYKCRQC
NAAIHKKCIDKIIGRCTGTAANSRDTIFQKERFNIDMPHRFKVYNYMSPTFCDHCGSLLWGLVK
QGLKCEDCGMNVHHKCQKKVANLCGINQKLLAEALNQVTQRSSRKSETESVGIYQNFERKPGVS
GDIAPGEDNGTYGKIWEGSTRCNIDNFIFHKVLGKGSFGKVLLVELKGKKEFFAIKALKKDVVL
IDDDVECTMVEKRVLALAWENPFLTHLFCTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFELYRA
TFYAAEIVCGLQFLHNKGIIYRDLKLDNVMLDQDGHIKIADFGMCKENIFGEKQASTFCGTPDY
IAPEILQGLKYSFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWITKESKDI
LEKLLERDTTKRLGVTGNIKIHPFFKTINWTLLEKRAVEPPFKPKVKSPGDYSNFDQEFLNEKA
RLSYTDKNLIDSMDQTAFAGFSFVNPKFERFLEK

hide sequence

RefSeq Acc Id:

ENSCAFP00000043544 ⟸ ENSCAFT00000081996

RefSeq Acc Id:

ENSCAFP00000012799 ⟸ ENSCAFT00000013836

RefSeq Acc Id:

ENSCAFP00000046558 ⟸ ENSCAFT00000061719

RefSeq Acc Id:	XP_038282423 ⟸ XM_038426495
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0PZJ7 (UniProtKB/TrEMBL), A0A8C0T441 (UniProtKB/TrEMBL), A0A8I3Q187 (UniProtKB/TrEMBL), A0A8P0NWP8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038282422 ⟸ XM_038426494
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0QVC9 (UniProtKB/TrEMBL), A0A8C0RU27 (UniProtKB/TrEMBL), A0A8I3PZJ7 (UniProtKB/TrEMBL), A0A8C0PZJ7 (UniProtKB/TrEMBL), A0A8C0T441 (UniProtKB/TrEMBL), A0A8I3Q187 (UniProtKB/TrEMBL), A0A8P0NWP8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038282425 ⟸ XM_038426497
- Peptide Label:	isoform X4
- UniProtKB:	A0A8C0PZJ7 (UniProtKB/TrEMBL), A0A8C0T441 (UniProtKB/TrEMBL), A0A8I3Q187 (UniProtKB/TrEMBL), A0A8P0NWP8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038282424 ⟸ XM_038426496
- Peptide Label:	isoform X3
- UniProtKB:	A0A8P0PGP6 (UniProtKB/TrEMBL), A0A8P0NU01 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCAFP00845039871 ⟸ ENSCAFT00845050861

RefSeq Acc Id:

ENSCAFP00845039935 ⟸ ENSCAFT00845050941

Protein Domains

AGC-kinase C-terminal C2 Phorbol-ester/DAG-type Protein kinase

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000008689	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030026134	UniProtKB/TrEMBL
	ENSCAFG00040019047	UniProtKB/TrEMBL
	ENSCAFG00845028762	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000013836.5	UniProtKB/TrEMBL
	ENSCAFT00000061719.2	UniProtKB/TrEMBL
	ENSCAFT00000081996.2	UniProtKB/TrEMBL
	ENSCAFT00000094117.1	UniProtKB/TrEMBL
	ENSCAFT00030048332.1	UniProtKB/TrEMBL
	ENSCAFT00030048335.1	UniProtKB/TrEMBL
	ENSCAFT00040035251.1	UniProtKB/TrEMBL
	ENSCAFT00040035374.1	UniProtKB/TrEMBL
	ENSCAFT00845050861	ENTREZGENE
	ENSCAFT00845050861.1	UniProtKB/TrEMBL
	ENSCAFT00845050941.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.150	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	3.30.60.20	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Transferase(Phosphotransferase) domain 1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	AGC-kinase_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	C1-like_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	C2_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	C2_domain_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	DAG/PE-bd	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Kinase-like_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PE/DAG-bd	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PKC_delta	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Pkinase_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Prot_kin_PKC_delta	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Prot_kinase_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Protein_kinase_ATP_BS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ser/Thr_kinase_AS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	cfa:494005	UniProtKB/Swiss-Prot
NCBI Gene	PRKCD	ENTREZGENE
PANTHER	PROTEIN KINASE C DELTA TYPE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SERINE/THREONINE-PROTEIN KINASE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	C1_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PKC_C2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Pkinase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Pkinase_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PIRSF	PKC_delta	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Protein_kin_C_delta	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS	DAGPEDOMAIN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	AGC_KINASE_CTER	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PROTEIN_KINASE_ATP	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PROTEIN_KINASE_DOM	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PROTEIN_KINASE_ST	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PS50004	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ZF_DAG_PE_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ZF_DAG_PE_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	S_TK_X	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	S_TKc	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SM00109	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF49562	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF56112	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF57889	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8C0PZJ7	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0QVC9	ENTREZGENE
	A0A8C0RU27	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0T441	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3PZJ7	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3Q187	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0NU01	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0NWP8	ENTREZGENE
	A0A8P0PGP6	ENTREZGENE, UniProtKB/TrEMBL
	KPCD_CANLF	UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary	A0A8P0NWP8	UniProtKB/TrEMBL
VGNC ID	VGNC:44979	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - PID (archival)

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - PID (archival)