CAPZB (capping actin protein of muscle Z-line subunit beta)

Gene: CAPZB (capping actin protein of muscle Z-line subunit beta) Canis lupus familiaris

Analyze

Symbol:

CAPZB

Name:

capping actin protein of muscle Z-line subunit beta

RGD ID:

12157546

Description:

ENCODES a protein that exhibits actin binding (inferred); actin filament binding (inferred); INVOLVED IN actin polymerization or depolymerization (ortholog); cell projection organization (ortholog); lamellipodium assembly (ortholog); ASSOCIATED WITH 3-Hydroxy-3-Methylglutaryl-CoA Lyase Deficiency (ortholog); Acute Coronary Syndrome (ortholog); Animal Mammary Neoplasms (ortholog); FOUND IN asymmetric synapse (ortholog); dendritic spine (ortholog); hippocampal mossy fiber to CA3 synapse (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

capping actin protein of muscle Z-line beta subunit; F-actin-capping protein subunit beta

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	79,182,668 - 79,311,529 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	79,181,851 - 79,311,518 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	75,695,344 - 75,825,750 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	79,804,060 - 79,934,792 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	79,804,081 - 79,934,830 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	76,565,507 - 76,695,821 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	77,575,195 - 77,705,390 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	78,644,515 - 78,775,092 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

3-Hydroxy-3-Methylglutaryl-CoA Lyase Deficiency (ISO)

Acute Coronary Syndrome (ISO)

Animal Mammary Neoplasms (ISO)

carcinoma (ISO)

chromosome 1p36 deletion syndrome (ISO)

congenital disorder of glycosylation Ir (ISO)

dementia (ISO)

Experimental Mammary Neoplasms (ISO)

hyperprolinemia type 2 (ISO)

Parkinson's disease 6 (ISO)

Spinal Cord Injuries (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

actin cytoskeleton organization (IEA)

actin filament capping (IEA)

actin polymerization or depolymerization (IEA,ISO)

barbed-end actin filament capping (IEA)

cell morphogenesis (IEA)

cell projection organization (IEA,ISO)

cytoskeleton organization (IEA)

lamellipodium assembly (IEA,ISO)

negative regulation of filopodium assembly (IEA)

regulation of cell morphogenesis (IEA)

regulation of lamellipodium assembly (IEA)

Cellular Component

asymmetric synapse (IEA,ISO)

brush border (IEA)

cortical cytoskeleton (IEA)

cytoplasm (IEA)

cytoskeleton (IEA)

dendritic spine (ISO)

F-actin capping protein complex (IEA)

hippocampal mossy fiber to CA3 synapse (IEA,ISO)

lamellipodium (IEA)

membrane (IEA)

neuronal cell body (ISO)

postsynaptic density (IEA,ISO)

Schaffer collateral - CA1 synapse (IEA,ISO)

sperm connecting piece (IEA)

WASH complex (IEA)

Molecular Function

actin binding (IEA)

actin filament binding (IEA)

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202	PMID:30404858	PMID:37756605

Genomics

Comparative Map Data

CAPZB
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	79,182,668 - 79,311,529 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	79,181,851 - 79,311,518 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	75,695,344 - 75,825,750 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	79,804,060 - 79,934,792 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	79,804,081 - 79,934,830 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	76,565,507 - 76,695,821 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	77,575,195 - 77,705,390 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	78,644,515 - 78,775,092 (+)	NCBI		UU_Cfam_GSD_1.0

CAPZB
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	19,338,775 - 19,485,539 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	19,338,775 - 19,485,539 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	19,665,269 - 19,812,033 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	19,537,860 - 19,684,579 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	19,411,069 - 19,491,551	NCBI
Celera	1	17,992,290 - 18,138,980 (-)	NCBI		Celera
Cytogenetic Map	1	p36.13	NCBI
HuRef	1	17,911,593 - 18,058,372 (-)	NCBI		HuRef
CHM1_1	1	19,774,569 - 19,921,335 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	19,162,310 - 19,308,992 (-)	NCBI		T2T-CHM13v2.0

Capzb
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	138,920,210 - 139,019,131 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	138,920,210 - 139,019,129 (+)	Ensembl		GRCm39 Ensembl
GRCm38	4	139,192,899 - 139,291,820 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	139,192,899 - 139,291,818 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	138,748,846 - 138,847,727 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	138,465,007 - 138,563,888 (+)	NCBI		MGSCv36	mm8
Celera	4	140,979,100 - 141,078,244 (+)	NCBI		Celera
Cytogenetic Map	4	D3	NCBI
cM Map	4	70.59	NCBI

Capzb
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	156,718,619 - 156,818,623 (+)	NCBI		GRCr8
mRatBN7.2	5	151,435,600 - 151,535,409 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	151,434,871 - 151,535,409 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	154,133,022 - 154,233,265 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	155,907,343 - 156,007,613 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	155,888,276 - 155,988,134 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	157,642,742 - 157,742,487 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	157,642,751 - 157,742,478 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	161,383,315 - 161,482,718 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	157,980,877 - 158,080,682 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	157,990,915 - 158,090,719 (+)	NCBI
Celera	5	149,816,061 - 149,915,748 (+)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

Capzb
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955452	30,589 - 169,693 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955452	34,454 - 168,514 (-)	NCBI	ChiLan1.0	ChiLan1.0

CAPZB
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	207,629,992 - 207,776,614 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	206,746,732 - 206,893,412 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	18,297,434 - 18,444,011 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	19,343,400 - 19,489,072 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	19,344,154 - 19,488,133 (-)	Ensembl	panpan1.1		panPan2

Capzb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	39,769,740 - 39,884,578 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936474	5,594,152 - 5,709,315 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936474	5,594,193 - 5,656,665 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CAPZB
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	77,780,682 - 77,912,617 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	77,780,682 - 77,912,653 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	71,842,816 - 71,985,460 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CAPZB
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	113,062,077 - 113,207,983 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	113,062,192 - 113,210,430 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666033	2,951,087 - 3,096,887 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Capzb
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624764	4,473,606 - 4,601,286 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624764	4,473,880 - 4,601,260 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in CAPZB
1544 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	reproductive system	respiratory system	adipose tissue
High
Medium	5	5	22	6	6	6	6	6	12	8	10	6
Low
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005617881	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005617882	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005617884	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022413975	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022413977	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022413980	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022413985	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038463877	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038463880	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038463882	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038470915	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038470916	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038470917	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038470918	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038531786	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038531787	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038531788	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038531789	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038596039	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038596040	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038596041	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038596042	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038596043	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038660128	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038660129	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038660130	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038660131	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000035	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000045	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000373	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCAFT00000024053 ⟹ ENSCAFP00000022331

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	2	79,217,552 - 79,311,518 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00000059581 ⟹ ENSCAFP00000062190

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	2	79,181,851 - 79,307,385 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00000064262 ⟹ ENSCAFP00000048521

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	2	79,188,467 - 79,307,385 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00000071971 ⟹ ENSCAFP00000050659

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	2	79,217,552 - 79,308,562 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00000080811 ⟹ ENSCAFP00000065479

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	2	79,217,552 - 79,307,385 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00000091118 ⟹ ENSCAFP00000062799

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	2	79,181,851 - 79,311,371 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00000093862 ⟹ ENSCAFP00000058595

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	2	79,207,494 - 79,307,385 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845005897 ⟹ ENSCAFP00845004687

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	2	79,804,081 - 79,934,830 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845005906 ⟹ ENSCAFP00845004696

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	2	79,804,081 - 79,934,821 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845005918 ⟹ ENSCAFP00845004707

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	2	79,805,241 - 79,934,830 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845005929 ⟹ ENSCAFP00845004716

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	2	79,840,182 - 79,934,092 (+)	Ensembl

RefSeq Acc Id:

XM_005617884 ⟹ XP_005617941

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	2	79,182,721 - 79,311,529 (+)	NCBI
Dog10K_Boxer_Tasha	2	75,696,526 - 75,825,243 (+)	NCBI

Sequence:

show sequence

ATGCACCCCAGCAGGCGCAGCCTCCCTTTCCCCCTGAACTGTCAGCTCGTGAGGGTTGGAACTG
CTGATTATGGAGGTGCCTCGGATCAGAGTGACCAGCAGCTGGACTGTGCCTTGGACTTGATGAG
GCGCCTGCCTCCACAGCAAATCGAGAAGAACCTCAGCGACCTGATCGACCTGGTCCCCAGTCTG
TGTGAAGATCTCCTGTCTTCTGTTGACCAGCCCCTGAAAATCGCCAGAGACAAGGTGGTGGGAA
AGGATTACCTTTTGTGTGACTACAACAGAGATGGGGACTCGTACAGGTCACCATGGAGTAACAA
GTATGACCCTCCTTTGGAAGACGGGGCCATGCCTTCTGCTCGGCTGAGAAAGCTGGAGGTGGAA
GCCAACAATGCCTTTGACCAGTATCGAGACCTGTATTTTGAAGGCGGTGTCTCGTCTGTCTACC
TCTGGGACCTGGATCATGGTTTTGCTGGAGTGATCCTCATAAAGAAGGCTGGAGATGGATCCAA
GAAGATCAAGGGTTGCTGGGATTCCATCCACGTGGTGGAAGTGCAGGAGAAATCCAGCGGTCGC
ACCGCCCATTACAAGCTGACCTCCACCGTGATGCTTTGGCTGCAGACCAACAAATCCGGCTCTG
GTACCATGAACCTCGGAGGCAGCCTGACCAGACAGATGGAGAAGGACGAGACCGTGAGCGACTG
CTCCCCGCACATAGCCAACATCGGGCGCCTGGTGGAGGACATGGAAAATAAAATCAGAAGTACG
CTGAATGAGATCTACTTTGGAAAAACAAAGGACATCGTCAACGGGCTGAGGTCTGTGCAGACTT
TCGCAGACAAATCAAAGCAAGAAGCTCTTAAGAACGACCTGGTGGAGGCCTTGAAGAGAAAGCA
GCAGTGTTAGAGCCCCGCTCCGCTCGCTCCGGACACGCCACGCGCTCGGTAGAGTCCTTTCTTA
GAAAACTCGTCTTCTGCCCCCGCCCCGCCCCGCCCCCACCAGGTCCCGTAACACCGGCATCGCG
ACCGCACAGCGCCATCTCCCCAGAATAAAGCCCAGTAAACACCCCTG

hide sequence

RefSeq Acc Id:

XM_022413975 ⟹ XP_022269683

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	2	79,182,668 - 79,308,552 (+)	NCBI
Dog10K_Boxer_Tasha	2	75,696,473 - 75,822,268 (+)	NCBI

Sequence:

show sequence

CCTTTTGGGGGGGCGCCCAGCGGGCCCCGAGGCCAACATACGGCCTGGACACGATGCACCCCAG
CAGGCGCAGCCTCCCTTTCCCCCTGAACTGTCAGCTCGTGAGGGTTGGAACTGCTGATTATGGA
GGTGCCTCGGATCAGAGTGACCAGCAGCTGGACTGTGCCTTGGACTTGATGAGGCGCCTGCCTC
CACAGCAAATCGAGAAGAACCTCAGCGACCTGATCGACCTGGTCCCCAGTCTGTGTGAAGATCT
CCTGTCTTCTGTTGACCAGCCCCTGAAAATCGCCAGAGACAAGGTGGTGGGAAAGGATTACCTT
TTGTGTGACTACAACAGAGATGGGGACTCGTACAGGTCACCATGGAGTAACAAGTATGACCCTC
CTTTGGAAGACGGGGCCATGCCTTCTGCTCGGCTGAGAAAGCTGGAGGTGGAAGCCAACAATGC
CTTTGACCAGTATCGAGACCTGTATTTTGAAGGCGGTGTCTCGTCTGTCTACCTCTGGGACCTG
GATCATGGTTTTGCTGGAGTGATCCTCATAAAGAAGGCTGGAGATGGATCCAAGAAGATCAAGG
GTTGCTGGGATTCCATCCACGTGGTGGAAGTGCAGGAGAAATCCAGCGGTCGCACCGCCCATTA
CAAGCTGACCTCCACCGTGATGCTTTGGCTGCAGACCAACAAATCCGGCTCTGGTACCATGAAC
CTCGGAGGCAGCCTGACCAGACAGATGGAGAAGGACGAGACCGTGAGCGACTGCTCCCCGCACA
TAGCCAACATCGGGCGCCTGGTGGAGGACATGGAAAATAAAATCAGAAGTACGCTGAATGAGAT
CTACTTTGGAAAAACAAAGGACATCGTCAACGGGCTGAGATCTGTTGACGTAATCCCCGACCAC
CCCAAGTTTCAGCAGCTGCAGAGGGAGCTTTCCCAAGTGCTGACCCAGCGCCAGATCCACATCC
AGCCTGATAACTAA

hide sequence

RefSeq Acc Id:

XM_038463877 ⟹ XP_038319805

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	2	75,695,344 - 75,825,750 (+)	NCBI

RefSeq Acc Id:

XM_038463880 ⟹ XP_038319808

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	2	75,695,344 - 75,825,750 (+)	NCBI

RefSeq Acc Id:

XM_038463882 ⟹ XP_038319810

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	2	75,695,344 - 75,803,492 (+)	NCBI

RefSeq Acc Id:

XM_038470915 ⟹ XP_038326843

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	2	76,566,628 - 76,695,821 (+)	NCBI

RefSeq Acc Id:

XM_038470916 ⟹ XP_038326844

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	2	76,566,681 - 76,695,821 (+)	NCBI

RefSeq Acc Id:

XM_038470917 ⟹ XP_038326845

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	2	76,565,507 - 76,692,346 (+)	NCBI

RefSeq Acc Id:

XM_038470918 ⟹ XP_038326846

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	2	76,566,624 - 76,673,615 (+)	NCBI

RefSeq Acc Id:

XM_038531786 ⟹ XP_038387714

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	2	78,645,647 - 78,775,092 (+)	NCBI

RefSeq Acc Id:

XM_038531787 ⟹ XP_038387715

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	2	78,645,700 - 78,775,092 (+)	NCBI

RefSeq Acc Id:

XM_038531788 ⟹ XP_038387716

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	2	78,644,515 - 78,771,619 (+)	NCBI

RefSeq Acc Id:

XM_038531789 ⟹ XP_038387717

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	2	78,645,643 - 78,752,845 (+)	NCBI

RefSeq Acc Id:

XM_038596039 ⟹ XP_038451967

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	2	77,576,314 - 77,705,390 (+)	NCBI

RefSeq Acc Id:

XM_038596040 ⟹ XP_038451968

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	2	77,576,367 - 77,705,390 (+)	NCBI

RefSeq Acc Id:

XM_038596041 ⟹ XP_038451969

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	2	77,582,086 - 77,701,925 (+)	NCBI

RefSeq Acc Id:

XM_038596042 ⟹ XP_038451970

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	2	77,575,195 - 77,701,925 (+)	NCBI

RefSeq Acc Id:

XM_038596043 ⟹ XP_038451971

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	2	77,576,310 - 77,683,212 (+)	NCBI

RefSeq Acc Id:

XM_038660128 ⟹ XP_038516056

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	2	79,805,188 - 79,934,792 (+)	NCBI

RefSeq Acc Id:

XM_038660129 ⟹ XP_038516057

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	2	79,805,241 - 79,934,792 (+)	NCBI

RefSeq Acc Id:

XM_038660130 ⟹ XP_038516058

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	2	79,804,060 - 79,931,318 (+)	NCBI

RefSeq Acc Id:

XM_038660131 ⟹ XP_038516059

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	2	79,805,184 - 79,912,585 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_005617941	(Get FASTA)	NCBI Sequence Viewer
	XP_022269683	(Get FASTA)	NCBI Sequence Viewer
	XP_038319805	(Get FASTA)	NCBI Sequence Viewer
	XP_038319808	(Get FASTA)	NCBI Sequence Viewer
	XP_038319810	(Get FASTA)	NCBI Sequence Viewer
	XP_038326843	(Get FASTA)	NCBI Sequence Viewer
	XP_038326844	(Get FASTA)	NCBI Sequence Viewer
	XP_038326845	(Get FASTA)	NCBI Sequence Viewer
	XP_038326846	(Get FASTA)	NCBI Sequence Viewer
	XP_038387714	(Get FASTA)	NCBI Sequence Viewer
	XP_038387715	(Get FASTA)	NCBI Sequence Viewer
	XP_038387716	(Get FASTA)	NCBI Sequence Viewer
	XP_038387717	(Get FASTA)	NCBI Sequence Viewer
	XP_038451967	(Get FASTA)	NCBI Sequence Viewer
	XP_038451968	(Get FASTA)	NCBI Sequence Viewer
	XP_038451969	(Get FASTA)	NCBI Sequence Viewer
	XP_038451970	(Get FASTA)	NCBI Sequence Viewer
	XP_038451971	(Get FASTA)	NCBI Sequence Viewer
	XP_038516056	(Get FASTA)	NCBI Sequence Viewer
	XP_038516057	(Get FASTA)	NCBI Sequence Viewer
	XP_038516058	(Get FASTA)	NCBI Sequence Viewer
	XP_038516059	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000022331.4
	ENSCAFP00000048521.2
	ENSCAFP00000050659.2
	ENSCAFP00000062799.2
	ENSCAFP00030012889.1
	ENSCAFP00030012961.1
	ENSCAFP00030013039.1
	ENSCAFP00030013058.1
	ENSCAFP00030013128.1
	ENSCAFP00040000351.1
	ENSCAFP00040000366.1
	ENSCAFP00040000386.1
	ENSCAFP00845004687.1
	ENSCAFP00845004696
	ENSCAFP00845004696.1
	ENSCAFP00845004707
	ENSCAFP00845004707.1
	ENSCAFP00845004716.1

RefSeq Acc Id:	XP_005617941 ⟸ XM_005617884
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0K5B7 (UniProtKB/TrEMBL), A0A8C0MPT3 (UniProtKB/TrEMBL), A0A8I3MHS5 (UniProtKB/TrEMBL), A0A8C0RUE3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MHPSRRSLPFPLNCQLVRVGTADYGGASDQSDQQLDCALDLMRRLPPQQIEKNLSDLIDLVPSL CEDLLSSVDQPLKIARDKVVGKDYLLCDYNRDGDSYRSPWSNKYDPPLEDGAMPSARLRKLEVE ANNAFDQYRDLYFEGGVSSVYLWDLDHGFAGVILIKKAGDGSKKIKGCWDSIHVVEVQEKSSGR TAHYKLTSTVMLWLQTNKSGSGTMNLGGSLTRQMEKDETVSDCSPHIANIGRLVEDMENKIRST LNEIYFGKTKDIVNGLRSVQTFADKSKQEALKNDLVEALKRKQQC hide sequence

RefSeq Acc Id:	XP_022269683 ⟸ XM_022413975
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0K5B2 (UniProtKB/TrEMBL), A0A8C0PK87 (UniProtKB/TrEMBL)
- Sequence:	show sequence MHPSRRSLPFPLNCQLVRVGTADYGGASDQSDQQLDCALDLMRRLPPQQIEKNLSDLIDLVPSL CEDLLSSVDQPLKIARDKVVGKDYLLCDYNRDGDSYRSPWSNKYDPPLEDGAMPSARLRKLEVE ANNAFDQYRDLYFEGGVSSVYLWDLDHGFAGVILIKKAGDGSKKIKGCWDSIHVVEVQEKSSGR TAHYKLTSTVMLWLQTNKSGSGTMNLGGSLTRQMEKDETVSDCSPHIANIGRLVEDMENKIRST LNEIYFGKTKDIVNGLRSVDVIPDHPKFQQLQRELSQVLTQRQIHIQPDN hide sequence

RefSeq Acc Id:

ENSCAFP00000058595 ⟸ ENSCAFT00000093862

RefSeq Acc Id:

ENSCAFP00000048521 ⟸ ENSCAFT00000064262

RefSeq Acc Id:

ENSCAFP00000062190 ⟸ ENSCAFT00000059581

RefSeq Acc Id:

ENSCAFP00000022331 ⟸ ENSCAFT00000024053

RefSeq Acc Id:

ENSCAFP00000065479 ⟸ ENSCAFT00000080811

RefSeq Acc Id:

ENSCAFP00000050659 ⟸ ENSCAFT00000071971

RefSeq Acc Id:

ENSCAFP00000062799 ⟸ ENSCAFT00000091118

RefSeq Acc Id:	XP_038326845 ⟸ XM_038470917
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038326846 ⟸ XM_038470918
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038326843 ⟸ XM_038470915
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038326844 ⟸ XM_038470916
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038451970 ⟸ XM_038596042
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038451971 ⟸ XM_038596043
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038451967 ⟸ XM_038596039
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038451968 ⟸ XM_038596040
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038451969 ⟸ XM_038596041
- Peptide Label:	isoform X5

RefSeq Acc Id:	XP_038516058 ⟸ XM_038660130
- Peptide Label:	isoform X3
- UniProtKB:	A0A8C0MN92 (UniProtKB/TrEMBL), A0A8I3MPZ8 (UniProtKB/TrEMBL), A0A8C0PK87 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038516059 ⟸ XM_038660131
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038516056 ⟸ XM_038660128
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0K5B2 (UniProtKB/TrEMBL), A0A8C0PK87 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038516057 ⟸ XM_038660129
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0K5B7 (UniProtKB/TrEMBL), A0A8C0MPT3 (UniProtKB/TrEMBL), A0A8I3MHS5 (UniProtKB/TrEMBL), A0A8C0RUE3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038319805 ⟸ XM_038463877
- Peptide Label:	isoform X6
- UniProtKB:	A0A8P0TEJ4 (UniProtKB/TrEMBL), A0A8C0PK87 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038319808 ⟸ XM_038463880
- Peptide Label:	isoform X7
- UniProtKB:	A0A8P0NYJ3 (UniProtKB/TrEMBL), A0A8C0RUE3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038319810 ⟸ XM_038463882
- Peptide Label:	isoform X8

RefSeq Acc Id:	XP_038387716 ⟸ XM_038531788
- Peptide Label:	isoform X3
- UniProtKB:	A0A8C0MN92 (UniProtKB/TrEMBL), A0A8C0PK87 (UniProtKB/TrEMBL), A0A8I3MPZ8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038387717 ⟸ XM_038531789
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038387714 ⟸ XM_038531786
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0K5B2 (UniProtKB/TrEMBL), A0A8C0PK87 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038387715 ⟸ XM_038531787
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0K5B7 (UniProtKB/TrEMBL), A0A8C0MPT3 (UniProtKB/TrEMBL), A0A8C0RUE3 (UniProtKB/TrEMBL), A0A8I3MHS5 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCAFP00845004696 ⟸ ENSCAFT00845005906

RefSeq Acc Id:

ENSCAFP00845004687 ⟸ ENSCAFT00845005897

RefSeq Acc Id:

ENSCAFP00845004707 ⟸ ENSCAFT00845005918

RefSeq Acc Id:

ENSCAFP00845004716 ⟸ ENSCAFT00845005929

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000015152	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030007943	UniProtKB/TrEMBL
	ENSCAFG00040000184	UniProtKB/TrEMBL
	ENSCAFG00845003322	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000024053.5	UniProtKB/TrEMBL
	ENSCAFT00000064262.2	UniProtKB/TrEMBL
	ENSCAFT00000071971.2	UniProtKB/TrEMBL
	ENSCAFT00000091118.2	UniProtKB/TrEMBL
	ENSCAFT00030014774.1	UniProtKB/TrEMBL
	ENSCAFT00030014853.1	UniProtKB/TrEMBL
	ENSCAFT00030014945.1	UniProtKB/TrEMBL
	ENSCAFT00030014971.1	UniProtKB/TrEMBL
	ENSCAFT00030015061.1	UniProtKB/TrEMBL
	ENSCAFT00040000432.1	UniProtKB/TrEMBL
	ENSCAFT00040000448.1	UniProtKB/TrEMBL
	ENSCAFT00040000472.1	UniProtKB/TrEMBL
	ENSCAFT00845005897.1	UniProtKB/TrEMBL
	ENSCAFT00845005906	ENTREZGENE
	ENSCAFT00845005906.1	UniProtKB/TrEMBL
	ENSCAFT00845005918	ENTREZGENE
	ENSCAFT00845005918.1	UniProtKB/TrEMBL
	ENSCAFT00845005929.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.58.570	UniProtKB/TrEMBL
	3.90.1150.210	UniProtKB/TrEMBL
	Capz alpha-1 subunit	UniProtKB/TrEMBL
InterPro	CapZ_alpha/beta	UniProtKB/TrEMBL
	CapZ_alpha/beta_2	UniProtKB/TrEMBL
	CAPZB	UniProtKB/TrEMBL
	CAPZB_N	UniProtKB/TrEMBL
	F-actin_capping_bsu_CS	UniProtKB/TrEMBL
KEGG Report	cfa:478209	UniProtKB/TrEMBL
NCBI Gene	CAPZB	ENTREZGENE
PANTHER	F-ACTIN-CAPPING PROTEIN SUBUNIT BETA	UniProtKB/TrEMBL
	PTHR10619	UniProtKB/TrEMBL
Pfam	F_actin_cap_B	UniProtKB/TrEMBL
PRINTS	FACTINCAPB	UniProtKB/TrEMBL
PROSITE	F_ACTIN_CAPPING_BETA	UniProtKB/TrEMBL
Superfamily-SCOP	SSF90096	UniProtKB/TrEMBL
UniProt	A0A8C0K5B2	ENTREZGENE
	A0A8C0K5B7	ENTREZGENE
	A0A8C0MKB1_CANLF	UniProtKB/TrEMBL
	A0A8C0MN92	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0MNF6_CANLF	UniProtKB/TrEMBL
	A0A8C0MPT3	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0PK87	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0PLZ1_CANLF	UniProtKB/TrEMBL
	A0A8C0RUE3	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3MHS5	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3MPZ8	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3MQR3_CANLF	UniProtKB/TrEMBL
	A0A8I3MSE7_CANLF	UniProtKB/TrEMBL
	A0A8P0NYJ3	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0TEJ4	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:52114	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2018-05-01	CAPZB	capping actin protein of muscle Z-line subunit beta		capping actin protein of muscle Z-line beta subunit	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD