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ONTOLOGY REPORT - ANNOTATIONS

Term:cyclic nucleotide binding
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Accession:GO:0030551 term browser browse the term
Definition:Binding to a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue.


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cyclic nucleotide binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase IDA 2',3'-cAMP, 2',3'-cNADP RGD PMID:19357238 RGD:6480491 NCBI chr10:85,511,164...85,517,723
Ensembl chr10:85,511,160...85,517,720 		JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B IDA RGD PMID:9013543 RGD:61587 NCBI chr 6:27,832,128...27,850,600
Ensembl chr 6:27,838,802...27,848,653 		JBrowse link
G Kcnh1 potassium voltage-gated channel subfamily H member 1 NOT|enables ISS
ISO		 GO_REF:0000024
(MGI:5616314|PMID:19671703)		 UniProt
RGD		 PMID:19671703 GO_REF:0000024 MGI:5616314 NCBI chr13:103,722,140...104,024,762
Ensembl chr13:103,722,245...104,024,740 		JBrowse link
2',3'-cyclic GMP-AMP binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc19a1 solute carrier family 19 member 1 enables ISO (PMID:31126740), (PMID:31511694) RGD PMID:31126740 PMID:31511694 NCBI chr20:11,584,410...11,602,429
Ensembl chr20:11,584,411...11,601,972 		JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 enables IDA
ISO
IEA
IBA		 PMID:26669264
(MGI:5487473|PMID:23258412), (MGI:5700266|PMID:26300263), (MGI:5787716|PMID:26669264)
GO_REF:0000107
(PMID:23747010), (PMID:26669264), (PMID:30842659), (PMID:30842662), (PMID:35388221)
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:23258412 PMID:23747010 PMID:26300263 PMID:26669264 PMID:30842659 More... GO_REF:0000033 GO_REF:0000107 MGI:5487473 MGI:5700266 MGI:5787716, RGD:11344949 NCBI chr18:27,332,119...27,338,371
Ensembl chr18:27,332,119...27,338,335 		JBrowse link
cAMP binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bves blood vessel epicardial substance enables IBA
ISO		 GO_REF:0000033
(PMID:22354168)		 GO_Central
RGD		 PMID:22354168 GO_REF:0000033 NCBI chr20:48,819,241...48,860,282
Ensembl chr20:48,822,308...48,857,472 		JBrowse link
G Cnbd2 cyclic nucleotide binding domain containing 2 enables ISO (PMID:24339785) RGD PMID:24339785 NCBI chr 3:144,819,166...144,884,825
Ensembl chr 3:144,819,195...144,901,583 		JBrowse link
G Cnga1 cyclic nucleotide gated channel subunit alpha 1 enables IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:34699778)		 Ensembl
UniProt
RGD		 PMID:34699778 GO_REF:0000024 GO_REF:0000107 NCBI chr14:35,566,947...35,605,065
Ensembl chr14:35,567,125...35,605,065 		JBrowse link
G Cnga2 cyclic nucleotide gated channel subunit alpha 2 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr  X:149,696,999...149,715,051
Ensembl chr  X:149,696,997...149,715,051 		JBrowse link
G Cnga4 cyclic nucleotide gated channel subunit alpha 4 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 1:159,752,357...159,756,369
Ensembl chr 1:159,752,357...159,756,375 		JBrowse link
G Cngb1 cyclic nucleotide gated channel subunit beta 1 enables IEA
IDA
ISO		 GO_REF:0000107
PMID:27405959
(PMID:34699778)		 Ensembl
RGD		 PMID:34699778 PMID:27405959 GO_REF:0000107, RGD:401966869 NCBI chr19:9,726,595...9,791,111
Ensembl chr19:9,726,595...9,791,173 		JBrowse link
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 enables ISS
ISO		 GO_REF:0000024
(MGI:5520040|PMID:22006928)
(PMID:28086084)		 UniProt
RGD		 PMID:22006928 PMID:28086084 GO_REF:0000024 MGI:5520040 NCBI chr 2:49,495,771...49,899,983
Ensembl chr 2:49,495,771...49,899,774 		JBrowse link
G Hcn2 hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 7:9,969,801...9,988,839
Ensembl chr 7:9,970,368...9,988,841 		JBrowse link
G Hcn3 hyperpolarization-activated cyclic nucleotide-gated potassium channel 3 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:174,551,861...174,567,459
Ensembl chr 2:174,551,680...174,565,966 		JBrowse link
G Hcn4 hyperpolarization activated cyclic nucleotide-gated potassium channel 4 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 8:59,222,206...59,259,626
Ensembl chr 8:59,221,653...59,259,639 		JBrowse link
G Pde10a phosphodiesterase 10A enables ISO (PMID:19689430) RGD PMID:19689430 NCBI chr 1:51,765,743...52,218,086
Ensembl chr 1:51,770,132...52,216,563 		JBrowse link
G Pde1c phosphodiesterase 1C IDA RGD PMID:7568196 RGD:68318 NCBI chr 4:85,300,858...85,777,948
Ensembl chr 4:85,300,858...85,863,219 		JBrowse link
G Pde2a phosphodiesterase 2A enables IEA
ISO		 GO_REF:0000107
(MGI:5294304|PMID:15210692)
(PMID:15938621)		 Ensembl
RGD		 PMID:15210692 PMID:15938621 GO_REF:0000107 MGI:5294304 NCBI chr 1:155,823,590...155,915,434
Ensembl chr 1:155,813,180...155,915,434 		JBrowse link
G Pde4a phosphodiesterase 4A enables ISO
IEA		 UniProtKB:P06776|UniProtKB:P22434 (PMID:8413254)
GO_REF:0000107		 RGD
Ensembl		 PMID:8413254 GO_REF:0000107 NCBI chr 8:19,690,816...19,753,538
Ensembl chr 8:19,703,290...19,751,961 		JBrowse link
G Pde4b phosphodiesterase 4B enables ISO
IEA		 UniProtKB:P06776|UniProtKB:P22434 (PMID:8413254)
GO_REF:0000107		 RGD
Ensembl		 PMID:8413254 GO_REF:0000107 NCBI chr 5:116,799,819...117,369,155
Ensembl chr 5:116,799,971...117,367,696 		JBrowse link
G Pde4d phosphodiesterase 4D enables IEA
ISO		 GO_REF:0000107
(PMID:15938621), (PMID:20819076), (PMID:9371713)		 Ensembl
RGD		 PMID:9371713 PMID:15938621 PMID:20819076 GO_REF:0000107 NCBI chr 2:40,014,933...41,529,190
Ensembl chr 2:40,019,933...41,525,884 		JBrowse link
G Popdc2 popeye domain containing 2 enables IBA
ISO		 GO_REF:0000033
(PMID:22354168)		 GO_Central
RGD		 PMID:22354168 GO_REF:0000033 NCBI chr11:62,351,843...62,398,688
Ensembl chr11:62,374,759...62,390,756 		JBrowse link
G Popdc3 popeye domain containing 3 enables ISO
IBA		 (MGI:5424322|PMID:22354168)
GO_REF:0000033		 RGD
GO_Central		 PMID:22354168 GO_REF:0000033 MGI:5424322 NCBI chr20:48,772,397...48,800,677
Ensembl chr20:48,772,462...48,800,593 		JBrowse link
G Prkar1a protein kinase cAMP-dependent type I regulatory subunit alpha enables IDA
IBA
IEA		 GO_REF:0000033
GO_REF:0000043		 GO_Central
UniProt
RGD		 PMID:11907174 GO_REF:0000033 GO_REF:0000043, RGD:2312572 NCBI chr10:94,621,042...94,639,534
Ensembl chr10:94,620,039...94,639,041 		JBrowse link
G Prkar1b protein kinase cAMP-dependent type I regulatory subunit beta enables IDA
IBA
IEA		 GO_REF:0000033
GO_REF:0000043		 GO_Central
UniProt
RGD		 PMID:11907174 GO_REF:0000033 GO_REF:0000043, RGD:2312572 NCBI chr12:15,492,233...15,624,942
Ensembl chr12:15,511,801...15,624,942 		JBrowse link
G Prkar2a protein kinase cAMP-dependent type II regulatory subunit alpha enables IDA
IBA
IEA		 GO_REF:0000033
GO_REF:0000043		 GO_Central
UniProt
RGD		 PMID:11907174 GO_REF:0000033 GO_REF:0000043, RGD:2312572 NCBI chr 8:109,393,189...109,458,832
Ensembl chr 8:109,395,833...109,455,628 		JBrowse link
G Prkar2b protein kinase cAMP-dependent type II regulatory subunit beta enables IDA
IBA
IEA		 GO_REF:0000033
GO_REF:0000043		 GO_Central
UniProt
RGD		 PMID:14625280 PMID:11907174 GO_REF:0000033 GO_REF:0000043, RGD:2312570, RGD:2312572 NCBI chr 6:48,563,659...48,653,933
Ensembl chr 6:48,563,662...48,653,933 		JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 enables
NOT|enables		 ISO
ISS		 (PMID:10801446)
GO_REF:0000024
(PMID:10548487), (PMID:10608844), (PMID:11359771)		 RGD
UniProt		 PMID:10548487 PMID:10608844 PMID:10801446 PMID:11359771 GO_REF:0000024 NCBI chr 2:164,207,513...164,322,157
Ensembl chr 2:164,207,513...164,244,247 		JBrowse link
G Rapgef3 Rap guanine nucleotide exchange factor 3 IPI RGD PMID:16244178 RGD:9850088 NCBI chr 7:128,875,772...128,898,203
Ensembl chr 7:128,875,773...128,898,521 		JBrowse link
G Rapgef4 Rap guanine nucleotide exchange factor 4 enables IDA
ISO
ISS
IEA		 (MGI:4412439|PMID:18660803)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:18660803 PMID:9856955 GO_REF:0000024 GO_REF:0000107 MGI:4412439, RGD:632397 NCBI chr 3:56,809,388...57,101,332
Ensembl chr 3:56,809,270...57,102,316 		JBrowse link
cGMP binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cnga1 cyclic nucleotide gated channel subunit alpha 1 enables IDA
ISO
IBA
IEA		 (PMID:34699778)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:34699778 PMID:18048449 GO_REF:0000033 GO_REF:0000107, RGD:6902904 NCBI chr14:35,566,947...35,605,065
Ensembl chr14:35,567,125...35,605,065 		JBrowse link
G Cnga2 cyclic nucleotide gated channel subunit alpha 2 enables IDA
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:18048449 PMID:22786723 GO_REF:0000033, RGD:6902904, RGD:7241219 NCBI chr  X:149,696,999...149,715,051
Ensembl chr  X:149,696,997...149,715,051 		JBrowse link
G Cnga3 cyclic nucleotide gated channel subunit alpha 3 enables NAS
ISO
IBA
IDA		 (PMID:24164424), (PMID:37463923)
GO_REF:0000033		 RGD
GO_Central		 PMID:24164424 PMID:37463923 PMID:10984544 PMID:11387380 GO_REF:0000033, RGD:70699, RGD:1600869 NCBI chr 9:39,447,534...39,494,044
Ensembl chr 9:39,448,034...39,493,183 		JBrowse link
G Cnga4 cyclic nucleotide gated channel subunit alpha 4 enables IDA
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:22786723 GO_REF:0000033, RGD:7241219 NCBI chr 1:159,752,357...159,756,369
Ensembl chr 1:159,752,357...159,756,375 		JBrowse link
G Cngb1 cyclic nucleotide gated channel subunit beta 1 enables IBA
IDA
ISO		 GO_REF:0000033
PMID:27405959
(PMID:24164424), (PMID:34699778)		 GO_Central
RGD		 PMID:24164424 PMID:34699778 PMID:27405959 GO_REF:0000033, RGD:401966869 NCBI chr19:9,726,595...9,791,111
Ensembl chr19:9,726,595...9,791,173 		JBrowse link
G Cngb3 cyclic nucleotide gated channel subunit beta 3 enables IBA
ISO		 GO_REF:0000033
(PMID:24164424), (PMID:37463923)		 GO_Central
RGD		 PMID:24164424 PMID:37463923 GO_REF:0000033 NCBI chr 5:32,746,988...32,995,121
Ensembl chr 5:32,746,988...32,995,121 		JBrowse link
G Pde10a phosphodiesterase 10A enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 1:51,765,743...52,218,086
Ensembl chr 1:51,770,132...52,216,563 		JBrowse link
G Pde11a phosphodiesterase 11A enables ISO
IEA		 (PMID:19689430)
GO_REF:0000107		 RGD
Ensembl		 PMID:19689430 GO_REF:0000107 NCBI chr 3:60,913,562...61,297,154
Ensembl chr 3:60,913,562...61,297,158 		JBrowse link
G Pde2a phosphodiesterase 2A enables ISO
IEA		 (PMID:15938621), (PMID:17329248), (PMID:19689430), (PMID:19828435)
(MGI:5294304|PMID:15210692), (MGI:5294310|PMID:12271124)
GO_REF:0000107		 RGD
Ensembl		 PMID:12271124 PMID:15210692 PMID:15938621 PMID:17329248 PMID:19689430 More... GO_REF:0000107 MGI:5294304 MGI:5294310 NCBI chr 1:155,823,590...155,915,434
Ensembl chr 1:155,813,180...155,915,434 		JBrowse link
G Pde5a phosphodiesterase 5A enables IEA
ISO		 GO_REF:0000107
(PMID:12554648), (PMID:18534985)		 Ensembl
RGD		 PMID:12554648 PMID:18534985 GO_REF:0000107 NCBI chr 2:210,858,515...211,003,480
Ensembl chr 2:210,858,063...210,999,701 		JBrowse link
G Pde6g phosphodiesterase 6G enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:105,721,502...105,726,150
Ensembl chr10:105,721,682...105,726,719 		JBrowse link
G Pde6h phosphodiesterase 6H enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:169,857,793...169,872,969
Ensembl chr 4:169,857,812...169,872,969 		JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 enables ISO (MGI:1890119|PMID:10671526) RGD PMID:10671526 MGI:1890119 NCBI chr 1:228,409,605...229,638,794
Ensembl chr 1:228,408,947...229,639,080 		JBrowse link
G Prkg2 protein kinase cGMP-dependent 2 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr14:10,559,882...10,668,479
Ensembl chr14:10,559,882...10,666,888 		JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 NOT|enables ISO (PMID:10608844), (PMID:11359771) RGD PMID:10608844 PMID:11359771 NCBI chr 2:164,207,513...164,322,157
Ensembl chr 2:164,207,513...164,244,247 		JBrowse link
cyclic-di-GMP binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sting1 stimulator of interferon response cGAMP interactor 1 enables ISO
IBA
IEA		 (PMID:22705373), (PMID:29694889)
GO_REF:0000033
GO_REF:0000107
(MGI:5487515|PMID:21947006), (MGI:5700266|PMID:26300263)		 RGD
GO_Central
Ensembl		 PMID:21947006 PMID:22705373 PMID:26300263 PMID:29694889 GO_REF:0000033 GO_REF:0000107 MGI:5487515 MGI:5700266 NCBI chr18:27,332,119...27,338,371
Ensembl chr18:27,332,119...27,338,335 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20486
    binding 17536
      small molecule binding 6115
        heterocyclic compound binding 2406
          nucleotide binding 2259
            cyclic nucleotide binding 38
              cAMP binding 25
              cGMP binding 15
              cyclic GMP-AMP binding + 2
              cyclic-di-AMP binding 0
              cyclic-di-GMP binding 1
paths to the root