Gene: Hcn4 (hyperpolarization activated cyclic nucleotide-gated potassium channel 4) Rattus norvegicus
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Symbol: Hcn4
Name: hyperpolarization activated cyclic nucleotide-gated potassium channel 4
Description: ENCODES a protein that exhibits identical protein binding (ortholog); intracellular cAMP activated cation channel activity (ortholog); voltage-gated potassium channel activity (ortholog); INVOLVED IN cellular response to aldosterone; response to cisplatin; cation transport (ortholog); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; ASSOCIATED WITH Hypertrophy, Left Ventricular; Arrhythmias, Cardiac (ortholog); arrhythmogenic right ventricular cardiomyopathy (ortholog); FOUND IN basolateral plasma membrane; neuron projection; neuronal cell body; INTERACTS WITH 6-propyl-2-thiouracil; amiodarone; ammonium chloride
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: hyperpolarization-activated cyclic nucleotide-gated potassium channel 4 (HCN4); hyperpolarization-activated, cyclic nucleotide-gated K+ 4; hyperpolarization-activated, cyclic nucleotide-gated potassium channel 4 (HCN4); potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0863,599,907 - 63,637,327 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0863,367,893 - 63,405,313 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.4862,629,828 - 62,667,248 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1862,648,881 - 62,686,299 (+)NCBI
Celera858,680,131 - 58,717,545 (+)NCBI
Cytogenetic Map8q24NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Hcn4
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
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RGD Object Information
RGD ID: 71065
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2017-05-30
Status: ACTIVE