Gene: Rapgef4 (Rap guanine nucleotide exchange factor 4) Rattus norvegicus
Symbol: Rapgef4
Name: Rap guanine nucleotide exchange factor 4
Description: ENCODES a protein that exhibits cAMP binding; guanyl-nucleotide exchange factor activity; protein complex binding; INVOLVED IN brain development; cellular response to nerve growth factor stimulus; ganglion development; ASSOCIATED WITH Burns; Autistic Disorder (ortholog); FOUND IN apical plasma membrane; axon; basolateral plasma membrane; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione; benzene
Type: protein-coding
RefSeq Status: MODEL
Also known as: CAMP-GEFII; cAMP-regulated guanine nucleotide exchange factor II; CAMPS; Cgef2; epac 2; Epac2; exchange factor directly activated by cAMP 2; exchange protein directly activated by cAMP 2; Rap guanine nucleotide exchange factor (GEF) 4
Orthologs:
Allele / Splice: Rapgef4Tn(sb-T2/Bart3)2.314Mcwi  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0358,632,338 - 58,925,127 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0365,122,705 - 65,409,814 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.4354,396,312 - 54,717,148 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1354,578,917 - 54,613,517 (+)NCBI
Celera356,352,070 - 56,643,335 (+)NCBI
Cytogenetic Map3q22NCBImapview
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Rapgef4
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 621886
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2016-09-06
Status: ACTIVE