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ONTOLOGY REPORT - ANNOTATIONS

Term:ubiquitin-like ligase-substrate adaptor activity
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Accession:GO:1990756 term browser browse the term
Definition:The binding activity of a molecule that brings together a ubiquitin-like ligase (including ubiquitin ligase and UFM1 ligase) and its substrate. Usually mediated by F-box BTB/POZ domain proteins.
Synonyms:exact_synonym: protein binding, bridging involved in substrate recognition for ubiquitination;   ubiquitin ligase substrate adaptor
 narrow_synonym: UFM1 ligase-substrate adaptor activity;   ubiquitin ligase-substrate adaptor activity


show annotations for term's descendants           Sort by:
ubiquitin-like ligase-substrate adaptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ambra1 autophagy and beclin 1 regulator 1 enables ISO
IBA		 (PMID:23524951)
(PMID:30166453), (PMID:33854232), (PMID:33854235), (PMID:33854239)
GO_REF:0000033		 RGD
GO_Central		 PMID:23524951 PMID:30166453 PMID:33854232 PMID:33854235 PMID:33854239 GO_REF:0000033 NCBI chr 3:77,700,936...77,890,221
Ensembl chr 3:77,700,936...77,890,221 		JBrowse link
G Ankrd9 ankyrin repeat domain 9 enables ISO (PMID:30293565) RGD PMID:30293565 NCBI chr 6:130,001,914...130,008,792
Ensembl chr 6:129,998,486...130,008,923 		JBrowse link
G Appbp2 amyloid beta precursor protein binding protein 2 enables ISS
ISO
IBA		 GO_REF:0000024
(PMID:26138980)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:26138980 GO_REF:0000024 GO_REF:0000033 NCBI chr10:70,057,774...70,099,877
Ensembl chr10:70,057,774...70,099,835 		JBrowse link
G Arrdc1 arrestin domain containing 1 enables ISO
ISS
IBA		 (PMID:27462458)
GO_REF:0000024
GO_REF:0000033		 RGD
UniProt
GO_Central		 PMID:27462458 GO_REF:0000024 GO_REF:0000033 NCBI chr 3:7,735,002...7,742,195
Ensembl chr 3:7,735,011...7,742,197 		JBrowse link
G Arrdc4 arrestin domain containing 4 enables ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:5804712|PMID:27462458)
(PMID:28594402)		 UniProt
Ensembl
RGD		 PMID:27462458 PMID:28594402 GO_REF:0000024 GO_REF:0000107 MGI:5804712 NCBI chr 1:122,369,355...122,383,351
Ensembl chr 1:122,369,360...122,383,290 		JBrowse link
G Axin1 axin 1 enables ISO
IEA		 (PMID:16601693)
GO_REF:0000107
(MGI:3628833|PMID:16601693)		 RGD
Ensembl		 PMID:16601693 GO_REF:0000107 MGI:3628833 NCBI chr10:15,163,477...15,215,615
Ensembl chr10:15,163,684...15,215,615 		JBrowse link
G Btrc beta-transducin repeat containing E3 ubiquitin protein ligase enables ISO (PMID:10066435), (PMID:11158290), (PMID:12820959), (PMID:22017875), (PMID:22017876), (PMID:22017877), (PMID:33110214), (PMID:36608670) RGD PMID:10066435 PMID:11158290 PMID:12820959 PMID:22017875 PMID:22017876 More... NCBI chr 1:244,210,299...244,380,126
Ensembl chr 1:244,210,314...244,376,721 		JBrowse link
G Cdc20 cell division cycle 20 enables IEA
ISO		 GO_REF:0000107
(PMID:27030811)		 Ensembl
RGD		 PMID:27030811 GO_REF:0000107 NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512 		JBrowse link
G Cdk5rap3 CDK5 regulatory subunit associated protein 3 enables ISO
ISS		 (PMID:36121123), (PMID:36543799), (PMID:37595036), (PMID:38383785), (PMID:38383789)
GO_REF:0000024		 RGD
UniProt		 PMID:36121123 PMID:36543799 PMID:37595036 PMID:38383785 PMID:38383789 GO_REF:0000024 NCBI chr10:81,894,393...81,903,581
Ensembl chr10:81,894,393...81,903,590 		JBrowse link
G Daw1 dynein assembly factor with WD repeats 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:84,435,552...84,472,632
Ensembl chr 9:84,435,552...84,472,635 		JBrowse link
G Dcaf1 DDB1 and CUL4 associated factor 1 enables ISO (PMID:23063525) RGD PMID:23063525 NCBI chr 8:107,466,229...107,540,633
Ensembl chr 8:107,474,312...107,540,627 		JBrowse link
G Dcaf12 DDB1 and CUL4 associated factor 12 enables ISO (PMID:29779948), (PMID:31267705), (PMID:34065512) RGD PMID:29779948 PMID:31267705 PMID:34065512 NCBI chr 5:56,460,418...56,482,171
Ensembl chr 5:56,461,006...56,482,456 		JBrowse link
G Dcaf13 DDB1 and CUL4 associated factor 13 enables ISO (PMID:30111536), (PMID:31492966)
(MGI:6202868|PMID:30111536), (MGI:6454628|PMID:31492966), (MGI:7432474|PMID:35178836)		 RGD PMID:30111536 PMID:31492966 PMID:35178836 MGI:6202868 MGI:6454628 MGI:7432474 NCBI chr 7:70,160,983...70,196,142
Ensembl chr 7:70,160,941...70,196,142 		JBrowse link
G Det1 DET1 partner of COP1 E3 ubiquitin ligase enables ISO
IBA		 UniProtKB:Q16531|UniProtKB:Q8NHY2 (PMID:14739464)
GO_REF:0000033		 RGD
GO_Central		 PMID:14739464 GO_REF:0000033 NCBI chr 1:132,749,736...132,765,963
Ensembl chr 1:132,749,756...132,765,923 		JBrowse link
G Fbxl19 F-box and leucine-rich repeat protein 19 enables ISO (PMID:22660580), (PMID:23512198) RGD PMID:22660580 PMID:23512198 NCBI chr 1:182,356,899...182,380,839
Ensembl chr 1:182,360,830...182,380,083 		JBrowse link
G Fbxl2 F-box and leucine-rich repeat protein 2 enables ISO (PMID:26037928)
(MGI:5488521|PMID:23542741)		 RGD PMID:23542741 PMID:26037928 MGI:5488521 NCBI chr 8:113,916,660...113,965,137
Ensembl chr 8:113,913,373...113,965,066 		JBrowse link
G Fbxo3 F-box protein 3 enables ISS
ISO		 GO_REF:0000024
(PMID:26037928)
(MGI:5488521|PMID:23542741)		 UniProt
RGD		 PMID:23542741 PMID:26037928 GO_REF:0000024 MGI:5488521 NCBI chr 3:90,417,262...90,449,557
Ensembl chr 3:90,417,297...90,449,557 		JBrowse link
G Fbxo38 F-box protein 38 enables ISO (PMID:30487606) RGD PMID:30487606 NCBI chr18:55,956,950...56,004,013
Ensembl chr18:55,956,959...56,003,961 		JBrowse link
G Fbxo4 F-box protein 4 enables ISO (PMID:29142209)
(MGI:6106241|PMID:29142209)		 RGD PMID:29142209 MGI:6106241 NCBI chr 2:53,174,798...53,187,792
Ensembl chr 2:53,174,798...53,187,792 		JBrowse link
G Fbxo42 F-box protein 42 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:153,451,162...153,509,564
Ensembl chr 5:153,451,153...153,506,342 		JBrowse link
G Fbxo45 F-box protein 45 enables ISO
IEA		 (PMID:29997255)
GO_REF:0000107		 RGD
Ensembl		 PMID:29997255 GO_REF:0000107 NCBI chr11:68,551,430...68,567,053
Ensembl chr11:68,551,122...68,566,800 		JBrowse link
G Fbxo7 F-box protein 7 enables ISO (PMID:15145941), (PMID:36646384) RGD PMID:15145941 PMID:36646384 NCBI chr 7:17,809,224...17,837,549
Ensembl chr 7:17,809,231...17,837,530 		JBrowse link
G Fbxo9 f-box protein 9 enables ISO
IEA		 (PMID:34480022)
GO_REF:0000107		 RGD
Ensembl		 PMID:34480022 GO_REF:0000107 NCBI chr 8:78,958,482...78,984,015
Ensembl chr 8:78,958,483...78,983,949 		JBrowse link
G Fbxw11 F-box and WD repeat domain containing 11 enables ISO (PMID:10321728), (PMID:10644755), (PMID:22017875), (PMID:22017876), (PMID:36608670) RGD PMID:10321728 PMID:10644755 PMID:22017875 PMID:22017876 PMID:36608670 NCBI chr10:17,232,735...17,330,574
Ensembl chr10:17,227,181...17,330,571 		JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 enables ISS
ISO		 GO_REF:0000024
(PMID:34741373)
(PMID:15150404)		 UniProt
RGD		 PMID:15150404 PMID:34741373 GO_REF:0000024 NCBI chr 2:170,149,706...170,311,536
Ensembl chr 2:170,149,694...170,309,941 		JBrowse link
G Fem1a fem-1 homolog A enables ISS
ISO		 GO_REF:0000024
(PMID:29779948), (PMID:33398168), (PMID:33398170)		 UniProt
RGD		 PMID:29779948 PMID:33398168 PMID:33398170 GO_REF:0000024 NCBI chr 9:1,091,695...1,093,901
Ensembl chr 9:1,090,527...1,100,628 		JBrowse link
G Fem1b fem-1 homolog B enables ISS
ISO		 GO_REF:0000024
(PMID:24076122), (PMID:29779948), (PMID:33398168), (PMID:33398170)
(MGI:6790336|PMID:34562363)		 UniProt
RGD		 PMID:24076122 PMID:29779948 PMID:33398168 PMID:33398170 PMID:34562363 GO_REF:0000024 MGI:6790336 NCBI chr 8:63,265,301...63,278,577
Ensembl chr 8:63,265,301...63,278,577 		JBrowse link
G Fem1c fem-1 homolog C enables ISO (PMID:26138980), (PMID:29775578), (PMID:29779948), (PMID:33398170) RGD PMID:26138980 PMID:29775578 PMID:29779948 PMID:33398170 NCBI chr18:39,232,900...39,258,692
Ensembl chr18:39,232,900...39,258,692 		JBrowse link
G Fzr1 fizzy and cell division cycle 20 related 1 enables ISO (PMID:14701726) RGD PMID:14701726 NCBI chr 7:8,332,029...8,343,953
Ensembl chr 7:8,332,029...8,343,952 		JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 enables ISO (PMID:21600962) RGD PMID:21600962 NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424 		JBrowse link
G Kbtbd2 kelch repeat and BTB domain containing 2 enables ISO (PMID:27708159) RGD PMID:27708159 NCBI chr 4:86,027,947...86,050,266
Ensembl chr 4:86,027,947...86,050,211 		JBrowse link
G Kctd17 potassium channel tetramerization domain containing 17 enables ISO (PMID:25270598) RGD PMID:25270598 NCBI chr 7:109,979,060...110,009,091
Ensembl chr 7:109,979,060...110,008,927 		JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 enables ISO
IEA		 (PMID:15572695)
GO_REF:0000107		 RGD
Ensembl		 PMID:15572695 GO_REF:0000107 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862 		JBrowse link
G Klhdc1 kelch domain containing 1 enables ISO (PMID:32200094) RGD PMID:32200094 NCBI chr 6:87,670,182...87,765,431
Ensembl chr 6:87,712,772...87,765,424 		JBrowse link
G Klhdc10 kelch domain containing 10 enables IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:29779948), (PMID:33909987)		 Ensembl
UniProt
RGD		 PMID:29779948 PMID:33909987 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:59,021,300...59,079,118
Ensembl chr 4:59,021,310...59,074,941 		JBrowse link
G Klhdc2 kelch domain containing 2 enables ISO
ISS		 (PMID:26138980), (PMID:29775578), (PMID:29779948), (PMID:30526872)
GO_REF:0000024		 RGD
UniProt		 PMID:26138980 PMID:29775578 PMID:29779948 PMID:30526872 GO_REF:0000024 NCBI chr 6:87,777,183...87,791,609
Ensembl chr 6:87,777,183...87,804,187 		JBrowse link
G Klhdc3 kelch domain containing 3 enables ISO
ISS
IEA		 (PMID:26138980), (PMID:29779948)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:26138980 PMID:29779948 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:14,302,345...14,308,736
Ensembl chr 9:14,302,354...14,308,736 		JBrowse link
G Klhl15 kelch-like family member 15 enables ISS
ISO		 GO_REF:0000024
(PMID:27561354), (PMID:35219381)		 UniProt
RGD		 PMID:27561354 PMID:35219381 GO_REF:0000024 NCBI chr  X:58,994,726...59,050,207
Ensembl chr  X:58,995,461...59,046,069 		JBrowse link
G Klhl2 kelch-like family member 2 enables IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:23838290)		 Ensembl
UniProt
RGD		 PMID:23838290 GO_REF:0000024 GO_REF:0000107 NCBI chr16:24,860,744...24,973,348
Ensembl chr16:24,860,667...24,973,341 		JBrowse link
G Klhl22 kelch-like family member 22 enables ISO (PMID:29769719), (PMID:33109719), (PMID:36394357) RGD PMID:29769719 PMID:33109719 PMID:36394357 NCBI chr11:83,190,891...83,231,746
Ensembl chr11:83,190,891...83,231,770 		JBrowse link
G Klhl25 kelch-like family member 25 enables ISS
ISO		 GO_REF:0000024
(MGI:6765767|PMID:34491895)
(PMID:22578813), (PMID:27664236), (PMID:34491895)		 UniProt
RGD		 PMID:22578813 PMID:27664236 PMID:34491895 GO_REF:0000024 MGI:6765767 NCBI chr 1:129,724,894...129,750,142
Ensembl chr 1:129,722,026...129,750,227 		JBrowse link
G Klhl3 kelch-like family member 3 enables IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:23387299), (PMID:23453970), (PMID:23576762), (PMID:35179207)		 Ensembl
UniProt
RGD		 PMID:23387299 PMID:23453970 PMID:23576762 PMID:35179207 GO_REF:0000024 GO_REF:0000107 NCBI chr17:6,523,089...6,645,971
Ensembl chr17:6,521,912...6,642,154 		JBrowse link
G LOC100909936 putative PRAME family member 24-like enables ISO (PMID:26138980) RGD PMID:26138980 NCBI chr14:14,420,434...14,423,091
Ensembl chr14:14,420,441...14,423,091
Ensembl chr14:14,420,441...14,423,091 		JBrowse link
G Pcmtd1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 enables ISO (PMID:35486881) RGD PMID:35486881 NCBI chr 5:12,284,711...12,355,680
Ensembl chr 5:12,284,711...12,354,899 		JBrowse link
G Pdcd6 programmed cell death 6 enables ISS
ISO		 GO_REF:0000024
(PMID:27716508)		 UniProt
RGD		 PMID:27716508 GO_REF:0000024 NCBI chr 1:28,966,518...28,982,188
Ensembl chr 1:28,966,518...28,982,189 		JBrowse link
G Pef1 penta-EF hand domain containing 1 enables ISS
ISO
IEA		 GO_REF:0000024
(PMID:27716508)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:27716508 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:142,451,791...142,475,061
Ensembl chr 5:142,451,778...142,475,067 		JBrowse link
G Pnkp polynucleotide kinase 3'-phosphatase enables ISO (MGI:5780352|PMID:26774286) RGD PMID:26774286 MGI:5780352 NCBI chr 1:95,341,465...95,346,921
Ensembl chr 1:95,341,620...95,346,920 		JBrowse link
G Pramef27 PRAME family member 27 enables ISO (PMID:26138980) RGD PMID:26138980 NCBI chr 5:155,752,765...155,759,663
Ensembl chr 5:155,756,015...155,759,663 		JBrowse link
G Pramex1 PRAME like, X-linked 1 enables ISO (PMID:21822215), (PMID:26138980) RGD PMID:21822215 PMID:26138980 NCBI chr  X:98,567,994...98,574,654
Ensembl chr  X:98,569,415...98,572,096 		JBrowse link
G Sh3bgrl1 SH3 domain binding glutamate rich protein like 1 enables ISO (PMID:34331014) RGD PMID:34331014 NCBI chr  X:74,167,029...74,263,783
Ensembl chr  X:74,166,871...74,263,783 		JBrowse link
G Skp1 S-phase kinase-associated protein 1 enables IEA
ISO		 GO_REF:0000107
(PMID:12820959)		 Ensembl
RGD		 PMID:12820959 GO_REF:0000107 NCBI chr10:36,401,987...36,417,066
Ensembl chr10:36,402,153...36,417,388 		JBrowse link
G Skp2 S-phase kinase associated protein 2 enables ISO (PMID:22464731)
(MGI:5438910|PMID:22464731)		 RGD PMID:22464731 MGI:5438910 NCBI chr 2:58,161,226...58,189,293
Ensembl chr 2:58,161,229...58,189,338 		JBrowse link
G Smad7 SMAD family member 7 enables ISO
IEA		 (PMID:11278251)
GO_REF:0000107		 RGD
Ensembl		 PMID:11278251 GO_REF:0000107 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765 		JBrowse link
G Spsb1 splA/ryanodine receptor domain and SOCS box containing 1 enables ISO UniProtKB:P35228|UniProtKB:Q15369|UniProtKB:Q93034 (PMID:21199876) RGD PMID:21199876 NCBI chr 5:160,358,292...160,418,541
Ensembl chr 5:160,358,308...160,418,468 		JBrowse link
G Spsb2 splA/ryanodine receptor domain and SOCS box containing 2 enables ISS
ISO
IEA		 GO_REF:0000024
UniProtKB:P35228|UniProtKB:Q15369|UniProtKB:Q93034 (PMID:21199876)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:21199876 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:157,613,404...157,615,293
Ensembl chr 4:157,613,401...157,615,284 		JBrowse link
G Spsb4 splA/ryanodine receptor domain and SOCS box containing 4 enables ISO UniProtKB:P35228|UniProtKB:Q15369|UniProtKB:Q93034 (PMID:21199876) RGD PMID:21199876 NCBI chr 8:97,536,519...97,609,757
Ensembl chr 8:97,536,520...97,609,787 		JBrowse link
G Suv39h2 SUV39H2 histone lysine methyltransferase enables ISO (PMID:30111536) RGD PMID:30111536 NCBI chr17:74,756,290...74,775,332
Ensembl chr17:74,756,306...74,775,332 		JBrowse link
G Trpc4ap transient receptor potential cation channel, subfamily C, member 4 associated protein enables ISO (PMID:29779948) RGD PMID:29779948 NCBI chr 3:144,122,003...144,192,986
Ensembl chr 3:144,122,003...144,192,986 		JBrowse link
G Vhl von Hippel-Lindau tumor suppressor enables ISO
ISS		 (PMID:24899725), (PMID:34290272)
GO_REF:0000024		 RGD
UniProt		 PMID:24899725 PMID:34290272 GO_REF:0000024 NCBI chr 4:146,772,483...146,779,376
Ensembl chr 4:146,772,468...146,779,377 		JBrowse link
G Wdr77 WD repeat domain 77 enables ISO (MGI:7334688|PMID:35197566) RGD PMID:35197566 MGI:7334688 NCBI chr 2:193,435,465...193,445,534
Ensembl chr 2:193,435,468...193,445,520 		JBrowse link
G Zswim8 zinc finger, SWIM-type containing 8 enables ISO (PMID:33184234), (PMID:33184237) RGD PMID:33184234 PMID:33184237 NCBI chr15:3,573,780...3,589,501
Ensembl chr15:3,573,780...3,589,487 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20487
    molecular adaptor activity 1140
      protein-macromolecule adaptor activity 984
        enzyme-substrate adaptor activity 73
          ubiquitin-like ligase-substrate adaptor activity 61
paths to the root