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ONTOLOGY REPORT - ANNOTATIONS

Term:mitotic G1/S transition checkpoint signaling
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Accession:GO:0044819 term browser browse the term
Definition:A cell cycle checkpoint that detects and negatively regulates progression from G1 to S phase as part of a mitotic cell cycle.
Synonyms:exact_synonym: mitotic G1/S transition checkpoint

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mitotic G1/S transition checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLK3 polo like kinase 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr20:87,989,573...87,995,396
Ensembl chr20:87,989,574...87,994,478 		JBrowse link
G PLK5 polo like kinase 5 (inactive) involved_in IEA TreeGrafter GO_REF:0000118 Ensembl chr 6:1,303,105...1,309,523 JBrowse link
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASP2 caspase 2 involved_in ISO (PMID:21726810) UniProt PMID:21726810 NCBI chr21:112,172,614...112,189,574
Ensembl chr21:112,172,733...112,188,744 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:35,445,668...35,454,334
Ensembl chr17:35,445,223...35,454,342 		JBrowse link
G CRADD CASP2 and RIPK1 domain containing adaptor with death domain involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:89,066,952...89,246,177 JBrowse link
G E2F7 E2F transcription factor 7 involved_in ISO (PMID:22802528) UniProt PMID:22802528 NCBI chr11:72,598,220...72,642,366
Ensembl chr11:72,599,353...72,641,420 		JBrowse link
G MDM2 MDM2 proto-oncogene involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:64,434,203...64,465,490
Ensembl chr11:64,434,261...64,469,890 		JBrowse link
G MUC1 mucin 1, cell surface associated involved_in ISO (PMID:15710329) BHF-UCL PMID:15710329 NCBI chr20:8,641,701...8,646,739
Ensembl chr20:8,642,842...8,646,962 		JBrowse link
G PCBP4 poly(rC) binding protein 4 involved_in ISO (PMID:10891498) UniProt PMID:10891498 NCBI chr22:13,326,069...13,336,474
Ensembl chr22:13,325,551...13,329,903 		JBrowse link
G PIDD1 p53-induced death domain protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:602,594...609,388
Ensembl chr 1:602,721...607,893 		JBrowse link
G PML PML nuclear body scaffold involved_in ISO (MGI:3580934|PMID:15626733) UniProt PMID:15626733 MGI:3580934 NCBI chr26:9,441,998...9,494,949
Ensembl chr26:9,451,112...9,494,931 		JBrowse link
G PPP2R5C protein phosphatase 2 regulatory subunit B'gamma involved_in ISO (PMID:17245430) UniProt PMID:17245430 NCBI chr24:79,703,316...79,875,379
Ensembl chr24:79,703,312...79,875,389 		JBrowse link
G PRAP1 proline rich acidic protein 1 involved_in ISO (PMID:23235459) UniProt PMID:23235459 NCBI chr26:53,195,600...53,201,846 JBrowse link
G RBM38 RNA binding motif protein 38 involved_in ISO (PMID:17050675) UniProt PMID:17050675 NCBI chr 2:6,709,975...6,727,534
Ensembl chr 2:6,711,458...6,727,353 		JBrowse link
G RPL26 ribosomal protein L26 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:7,733,652...7,740,384
Ensembl chr16:7,732,921...7,740,325 		JBrowse link
G TP53 tumor protein p53 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16107883) Ensembl
MGI		 PMID:16107883 GO_REF:0000107 NCBI chr16:7,047,686...7,065,567
Ensembl chr16:7,045,146...7,066,223 		JBrowse link
mitotic G1 DNA damage checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCND1 cyclin D1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:4,909,616...4,922,272
Ensembl chr 1:4,907,353...4,922,357 		JBrowse link
G DGKZ diacylglycerol kinase zeta involved_in ISO (PMID:16286473) UniProt PMID:16286473 NCBI chr 1:18,949,360...18,997,957
Ensembl chr 1:18,948,425...18,982,354 		JBrowse link
G FBXO31 F-box protein 31 involved_in ISO (PMID:19412162) UniProt PMID:19412162 NCBI chr 5:72,696,868...72,752,480
Ensembl chr 5:72,701,136...72,752,989 		JBrowse link
G GIGYF2 GRB10 interacting GYF protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19744960) Ensembl
MGI		 PMID:19744960 GO_REF:0000107 NCBI chr10:118,720,668...118,883,299
Ensembl chr10:118,720,690...118,874,162 		JBrowse link
G PRKDC protein kinase, DNA-activated, catalytic subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:43,915,226...44,119,547
Ensembl chr 8:43,914,636...44,119,541 		JBrowse link
G RFWD3 ring finger and WD repeat domain 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:53,045,408...53,092,214
Ensembl chr 5:53,045,465...53,092,494 		JBrowse link
G RPA2 replication protein A2 involved_in ISO (PMID:21731742) UniProt PMID:21731742 NCBI chr20:104,882,739...104,904,612 JBrowse link
G RPA2 replication protein A2 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr20:104,883,027...104,904,951 JBrowse link
G RPS27L ribosomal protein S27 like involved_in ISO (PMID:18056458) UniProt PMID:18056458 NCBI chr26:20,385,684...20,389,351 JBrowse link
G SDE2 SDE2 telomere maintenance homolog involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:3,779,561...3,793,496
Ensembl chr25:3,779,560...3,795,893 		JBrowse link
G TP53 tumor protein p53 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16107883) Ensembl
MGI		 PMID:16107883 GO_REF:0000107 NCBI chr16:7,047,686...7,065,567
Ensembl chr16:7,045,146...7,066,223 		JBrowse link
G TREX1 three prime repair exonuclease 1 acts_upstream_of_or_within ISO (PMID:23993650)
(PMID:18045533)		 MGI PMID:18045533 PMID:23993650 NCBI chr22:9,869,502...9,871,659 JBrowse link
G WAC WW domain containing adaptor with coiled-coil involved_in ISO (PMID:21329877) UniProt PMID:21329877 NCBI chr 9:28,131,774...28,222,501
Ensembl chr 9:28,131,769...28,219,134 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16925
    cellular process 15870
      cell cycle process 1306
        mitotic cell cycle process 756
          mitotic cell cycle checkpoint signaling 142
            mitotic G1/S transition checkpoint signaling 28
              mitotic G1 DNA damage checkpoint signaling + 26
Path 2
Term Annotations click to browse term
  biological_process 16925
    biological regulation 11599
      regulation of biological process 11243
        regulation of cellular process 10711
          regulation of cell cycle 1042
            regulation of cell cycle process 734
              negative regulation of cell cycle process 298
                negative regulation of cell cycle phase transition 249
                  cell cycle checkpoint signaling 184
                    mitotic cell cycle checkpoint signaling 142
                      mitotic G1/S transition checkpoint signaling 28
                        mitotic G1 DNA damage checkpoint signaling + 26
paths to the root