FBXO31 (F-box protein 31) - Rat Genome Database

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Gene: FBXO31 (F-box protein 31) Chlorocebus sabaeus
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Symbol: FBXO31
Name: F-box protein 31
RGD ID: 18455175
Description: ENCODES a protein that exhibits cyclin binding (ortholog); INVOLVED IN anaphase-promoting complex-dependent catabolic process (ortholog); DNA damage response (ortholog); mitotic G1 DNA damage checkpoint signaling (ortholog); ASSOCIATED WITH 16Q24.3 Microdeletion Syndrome (ortholog); autosomal recessive intellectual developmental disorder 45 (ortholog); congenital nongoitrous hypothyroidism 2 (ortholog); FOUND IN centrosome (ortholog); neuronal cell body (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: F-box only protein 31
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1572,696,868 - 72,752,480 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl572,701,136 - 72,752,989 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660472,944,370 - 3,001,044 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
FBXO31
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1572,696,868 - 72,752,480 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl572,701,136 - 72,752,989 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660472,944,370 - 3,001,044 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
FBXO31
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381687,326,987 - 87,392,121 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1687,326,987 - 87,392,142 (-)EnsemblGRCh38hg38GRCh38
GRCh371687,360,593 - 87,425,727 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361685,920,443 - 85,974,864 (-)NCBINCBI36Build 36hg18NCBI36
Build 341685,920,444 - 85,974,864NCBI
Celera1671,659,646 - 71,722,476 (-)NCBICelera
Cytogenetic Map16q24.2NCBI
HuRef1673,106,044 - 73,168,796 (-)NCBIHuRef
CHM1_11688,774,754 - 88,837,518 (-)NCBICHM1_1
T2T-CHM13v2.01693,397,874 - 93,463,013 (-)NCBIT2T-CHM13v2.0
Fbxo31
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398122,276,182 - 122,305,607 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8122,276,179 - 122,305,545 (-)EnsemblGRCm39 Ensembl
GRCm388121,549,443 - 121,578,864 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8121,549,440 - 121,578,806 (-)EnsemblGRCm38mm10GRCm38
MGSCv378124,075,879 - 124,102,706 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368124,437,993 - 124,464,843 (-)NCBIMGSCv36mm8
Celera8125,773,510 - 125,800,328 (-)NCBICelera
Cytogenetic Map8E1NCBI
cM Map870.65NCBI
Fbxo31
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81966,533,437 - 66,564,674 (-)NCBIGRCr8
mRatBN7.21949,624,813 - 49,656,052 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1949,627,686 - 49,656,010 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1956,418,500 - 56,446,780 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01957,102,655 - 57,130,983 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01959,317,009 - 59,345,307 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01953,487,610 - 53,625,673 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1953,487,613 - 53,625,673 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01964,224,819 - 64,363,108 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41951,836,918 - 51,837,223 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1948,874,360 - 48,902,812 (-)NCBICelera
Cytogenetic Map19q12NCBI
Fbxo31
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555411,811,010 - 1,828,724 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555411,811,010 - 1,828,734 (-)NCBIChiLan1.0ChiLan1.0
FBXO31
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21897,087,090 - 97,139,973 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan116103,000,732 - 103,056,347 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01667,997,481 - 68,053,081 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11687,322,364 - 87,377,104 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1687,322,364 - 87,377,104 (-)Ensemblpanpan1.1panPan2
FBXO31
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1565,703,591 - 65,734,956 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl565,703,575 - 65,731,056 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha565,701,948 - 65,746,369 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0565,912,307 - 65,956,714 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1565,936,368 - 65,980,668 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0565,768,645 - 65,813,053 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0566,182,624 - 66,227,196 (+)NCBIUU_Cfam_GSD_1.0
Fbxo31
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934926,048,159 - 26,078,443 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366411,801,548 - 1,830,440 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366411,801,539 - 1,831,988 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FBXO31
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl61,949,276 - 1,995,462 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.161,949,254 - 1,995,459 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.262,037,200 - 2,081,398 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Fbxo31
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247463,043,600 - 3,078,223 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247463,034,458 - 3,078,230 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 35 49
Low 1 20 11
Below cutoff

Sequence


RefSeq Acc Id: ENSCSAT00000001165   ⟹   ENSCSAP00000014905
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl572,701,136 - 72,752,989 (-)Ensembl
RefSeq Acc Id: XM_007994290   ⟹   XP_007992481
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1572,699,170 - 72,752,480 (-)NCBI
Vero_WHO_p1.0NW_0236660472,944,374 - 3,001,044 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007994291   ⟹   XP_007992482
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1572,696,868 - 72,752,480 (-)NCBI
Vero_WHO_p1.0NW_0236660472,944,377 - 3,001,044 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007994292   ⟹   XP_007992483
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1572,699,170 - 72,752,480 (-)NCBI
Vero_WHO_p1.0NW_0236660472,944,375 - 3,001,044 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007994293   ⟹   XP_007992484
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1572,702,985 - 72,752,480 (-)NCBI
Vero_WHO_p1.0NW_0236660472,944,374 - 2,994,557 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038008183   ⟹   XP_037864111
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660472,944,370 - 2,995,133 (+)NCBI
RefSeq Acc Id: XM_038008184   ⟹   XP_037864112
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660472,944,370 - 2,996,670 (+)NCBI
RefSeq Acc Id: XP_007992482   ⟸   XM_007994291
- Peptide Label: isoform X3
- UniProtKB: A0A0D9S216 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007992483   ⟸   XM_007994292
- Peptide Label: isoform X4
- UniProtKB: A0A0D9S216 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007992481   ⟸   XM_007994290
- Peptide Label: isoform X1
- UniProtKB: A0A0D9S216 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007992484   ⟸   XM_007994293
- Peptide Label: isoform X5
RefSeq Acc Id: ENSCSAP00000014905   ⟸   ENSCSAT00000001165
RefSeq Acc Id: XP_037864112   ⟸   XM_038008184
- Peptide Label: isoform X2
- UniProtKB: A0A0D9S216 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037864111   ⟸   XM_038008183
- Peptide Label: isoform X2
- UniProtKB: A0A0D9S216 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000003136 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000001165.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1280.50 UniProtKB/TrEMBL
InterPro F-box-like_dom_sf UniProtKB/TrEMBL
  F-box_dom UniProtKB/TrEMBL
  FBXO31/39 UniProtKB/TrEMBL
KEGG Report csab:103233425 UniProtKB/TrEMBL
NCBI Gene FBXO31 ENTREZGENE
PANTHER F-BOX ONLY PROTEIN 31 UniProtKB/TrEMBL
  PTHR10706 UniProtKB/TrEMBL
Pfam Cyclin_D1_bind UniProtKB/TrEMBL
  F-box-like UniProtKB/TrEMBL
PROSITE FBOX UniProtKB/TrEMBL
SMART FBOX UniProtKB/TrEMBL
Superfamily-SCOP SSF81383 UniProtKB/TrEMBL
UniProt A0A0D9S216 ENTREZGENE, UniProtKB/TrEMBL